Iodine-123-α-methyl tyrosine in gliomas: Correlation with cellular density and proliferative activity

Journal of Nuclear Medicine

Volumn 38, Issue 10, 1997, Pages 1551-1555

  Kuwert, Torsten ^a   Probst Cousin, Stefan ^a   Woesler, Burkhard ^a   Morgenroth, Carlo ^a   Lerch, Hartmut ^a   Matheja, Peter ^a   Palkovic, Stefan ^a   Schäfers, Michael ^a   Wassmann, Hansdetlef ^a   Gullotta, Filippo ^a   Schober, Otmar ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Cellular density; Gliomas; Iodine 123 methyl tyrosine; Radionuclide imaging; SPECT

Indexed keywords

IODINE 123; KI 67 ANTIGEN; METIROSINE; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; AMINO ACID TRANSPORT; ARTICLE; CELL DENSITY; CELL PROLIFERATION; CLINICAL ARTICLE; FEMALE; GLIOMA; HUMAN; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MALE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ASTROCYTOMA; BRAIN; BRAIN NEOPLASMS; CELL DIVISION; FEMALE; GLIOBLASTOMA; HUMANS; IODINE RADIOISOTOPES; MALE; METHYLTYROSINES; MIDDLE AGED; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 9844228506     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Herholz K. Tracers for clinical evaluation of gliomas: a neurologist's view. In: Mazoyer BM, Heiss WD, Comar D, et al., eds. PET studies on amino acid metabolism and protein synthesis. Dordrecht, The Netherlands: Kluwer Academic Publishers; 1993:203-214.
2. Conti PS. Introduction to imaging brain tumor metabolism with positron emission tomography. Cancer Invest 1995;13:244-259.
3. Leeds NE, Jackson EF. Current imaging techniques for the evaluation of brain neoplasms. Curr Opin Oncol 1994;6:254-261.
4. 123I]iodo-α-methyl tyrosine and SPECT. J Nucl Med 1989;30:110-112.
5. 124IMT and first clinical results. J Nucl Med 1990;31:281-286.
6. 123I]iodo-α-methyl tyrosine: competition with natural L-amino acids. J Nucl Med 1991;32:1225-1228.
7. Kawai K, Fujibayashi Y, Saji H, et al. A strategy for the study of cerebral amino acid transport using iodine-123-labeled amino acid radiopharmaceutical: 3-iodo-alpha-methyl-L-tyrosine. J Nucl Med 1991;32:819-824.
8. 11C-labeled L-methionine and D-methionine. J Nucl Med 1985;26:98-99.
9. 11C)-methionine in brain tumors studied with positron emission tomography. Acta Radiol 1987;28:225-229.
10. Ishiwata K, Kubota K, Murakami M, et al. Re-evaluation of amino acid PET studies: can the protein synthesis rates in brain and tumor tissues be measured in vivo? J Nucl Med 1993;34:1936-1943.
11. Kleihues P, Burger PC, Scheithauer BW. The new WHO classification of brain tumors. Brain Pathol 1993;3:255-268.
12. Cattoretti G, Becker MHG, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992;168:357-363.
13. Morimura T, Kitz K, Budka H. In situ analysis of cell kinetics in brain tumors. Acta Neuropathol 1989;77:276-282.
14. Kuwert T, Morgenroth C, Woesler B, et al. Uptake of iodine-123-α-methyl tyrosine by primary brain tumors and non-neoplastic brain lesions. Eur J Nucl Med 1996;23:1345-1353.
15. Kuwert T, Morgenroth C, Woesler B, et al. Influence of size of regions of interest on the measurement of uptake of iodine-123-̈-methyl tyrosine by brain tumors. Nucl Med Commun 1996;17:609-615.
16. Kuikka JT, Tenhunen-Eskelinen M, Jurvelin J, Kiliänen H. Physical performance of the Siemens Multi SPECT 3 gamma camera. Nucl Med Commun 1993;14:490-497.
17. Chang LT. A method of for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci 1978;2:2780-2789.
18. Bortz J. Lehrbuch der Statistik, 2nd Ed. Berlin: Springer; 1985.
19. Schober O, Meyer G-J, Duden C, et al. Uptake of amino acids in brain tumours using positron emission tomography as an indicator for assessing metabolic activity and malignancy. Fortsch Röntgenstr 1987;147:503-509.
20. Derlon JM, Bourdet C, Bustany P, et al. Carbon-11-L-methionine uptake in gliomas. Neurosurgery 1989;25:720-728.
21. Ogawa T, Shishido F, Kanno I, et al. Cerebral glioma: evaluation with methionine PET. Radiology 1993;186:45-53.
22. Burger PC. The grading of astrocytomas and oligodendrogliomas. In: Fields WS, ed. Brain tumors: a review of histologic classification. New York: Springer, 1989:171-180.
23. Herholz K, Pietrzyk U, Voges J, et al. Correlation of glucose consumption and tumor cell density in astrocytomas. A stereotactic PET study. J Neurosurg 1993;79:853-858.
24. 18FDG-PET in intracranial meningiomas versus grading, proliferation index, cellular density and cytogenetical analysis. Nuklearmedizin 1994;33:144-149.
25. Isselbacher KJ. Increased uptake of amino acids and 2-deoxy-D-glucose by virus-transformed cells in culture. Proc Natl Acad Sci USA 1972;69:585-589.
26. Saier MH Jr, Daniels GA, Boerner P, Lin J. Neutral amino acid transport systems in animal cells: potential targets of oncogene action and regulators of cellular growth. J Membr Biol 1988;104:1-20.
27. Leskinen-Kallio S, Ruotsalainen U, Nagren K, Teräs M, Joensuu H. Uptake of carbon-11-methionine and fluorodeoxyglucose in non-Hodgkin's lymphoma: a PET study. J Nucl Med 1991;32:1211-1218.
28. Miyazawa H, Arai T, Lio M, Hara T. PET imaging of non-small-cell lung carcinoma with carbon-11-methionine: relationship between radioactivity uptake and flow-cytometric parameters. J Nucl Med 1993;34:1886-1891.
29. 11C-methionine in breast cancer studied by PET. An association with the size of S-phase fraction. Br J Cancer 1991;64:1121-1124.
30. Lantos PL, Vandenberg SR, Kleihues P. Astrocytic tumours. In: Graham DJ, Lantos PL, eds. Greenfield's neuropathology, 6th Ed. London: Arnold; 1997:600-627.
31. Kuwert T, Sures T, Herzog H, et al. On the influence of spatial resolution and of the size and the form of regions of interest on the measurement of regional cerebral metabolic rates by positron emission tomography. J Neural Transm 1992;37(suppl): 53-66.
32. Kubota R, Kubota K, Yamada S, et al. Methionine uptake by tumor tissue: a microautoradiographic comparison with FDG. J Nucl Med 1995;36:484-492.
33. Oriuchi N, Tamura M, Shibazaki T, et al. Clinical evaluation of thallium-201 SPECT in supratentorial gliomas: relationship to histological grade, prognosis and proliferative activities. J Nucl Med 1993;34:2085-2089.
34. Ishibashi M, Taguchi A, Sugita Y, et al. Thallium-201 in brain tumors: relationship between tumor cell activity in astrocytic tumor and proliferation cell nuclear antigen. J Nucl Med 1995;36:2201-2206.
35. Takekawa H, Itoh K, Abe S, et al. Thallium-201 uptake, histopathological differentiation and Na-K ATPase in lung adenocarcinoma. J Nucl Med 1996;37:955-958.
36. Tonami N. Thallium-201 SPECT in lhe evaluation of gliomas. J Nucl Med 1993;34: 2089-2090.