2,3-Diphenylpropionic acids as potent VLA-4 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 1, 2005, Pages 217-220

  Hoshina, Yoichiro ^a   Ikegami, Satoru ^a   Okuyama, Akihiko ^a   Fukui, Hideto ^a   Inoguchi, Kiyoshi ^a   Maruyama, Tatsuya ^a   Fujimoto, Kyoko ^a   Matsumura, Yuzuru ^a   Aoyama, Akinori ^a   Harada, Tatsuhiro ^a   Tanaka, Hiroshi ^b   Nakamura, Tsutomu ^a  

^a KAKEN PHARMACEUTICAL CO LTD   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

2,3 Diphenylpropionic acid; VCAM 1; VLA 4

Indexed keywords

PROPIONIC ACID DERIVATIVE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 1; VERY LATE ACTIVATION ANTIGEN 1 ANTAGONIST;

ANIMAL CELL; ARTICLE; CELL ADHESION; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; INTEGRIN ALPHA4BETA1; PROPIONIC ACIDS;

EID: 9744263215     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.09.089     Document Type: Article

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