Effect of dexamethasone on perioperative renal function impairment during cardiac surgery with cardiopulmonary bypass

British Journal of Anaesthesia

Volumn 93, Issue 6, 2004, Pages 793-798

  Loef, B G ^a   Henning, R H ^a   Epema, A H ^a   Rietman, G W ^a   van Oeveren, W ^a   Navis, G J ^a   Ebels, T ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Complications, renal damage; Heart, cardiopulmonary bypass; Markers, renal; Steroid, dexamethasone

Indexed keywords

ACETYLGLUCOSAMINIDASE; ALBUMIN; BIOCHEMICAL MARKER; CEFUROXIME; CREATININE; DEXAMETHASONE; DIAZEPAM; DOPAMINE; GLUCOSE; HEPARIN; INSULIN; LOCAL ANESTHETIC AGENT; MIDAZOLAM; PANCURONIUM; PLACEBO; SODIUM; SUFENTANIL;

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY SURGERY; CREATININE CLEARANCE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; FEMALE; FREE WATER CLEARANCE; GLOMERULUS FILTRATION; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; GLUCOSURIA; HEART SURGERY; HEPARINIZATION; HUMAN; INTENSIVE CARE UNIT; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE DAMAGE; KIDNEY TUBULE FUNCTION; MALE; MICROALBUMINURIA; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTECTION; RANDOMIZED CONTROLLED TRIAL; SKIN INCISION; SODIUM EXCRETION; STATISTICAL SIGNIFICANCE; SURGICAL RISK; TIME;

EID: 9744258712     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeh266     Document Type: Article

References (24)

1. Mangano CM, Diamondstone LS, Ramsay JG, Aggarwal A, Herskowitz A, Mangano DT. Renal dysfunction after myocardial revascularization: risk factors, adverse outcomes, and hospital resource utilization. Ann Intern Med 1998; 128: 194-203
2. Loef BG, Epema AH, Navis G, Ebels T, van Oeveren W, Henning RH. Off-pump coronary revascularization attenuates transient renal damage compared with on-pump coronary revascularization. Chest 2002; 121: 1190-4
3. Ramsay JG. The respiratory, renal, and hepatic systems: effect of cardiac surgery and cardiopulmonary bypass. In: Mora CT, ed. Cardiopulmonary Bypass. New York, NY: Springer-Verlag, 1995; 147-68
4. Asimakopoulos G, Smith PLC, Ratnatunga CP, Taylor KM. Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass. Ann Thorac Surg 1999; 68: 1107-15
5. Boyle EM, Pohlman TH, Johnson MC, Verrier MC. Endothelial cell injury in cardiovascular surgery: the systemic inflammatory response. Ann Thorac Surg 1997; 63: 277-84
6. Jansen NJG, van Oeveren W, van den Broek L, et al. Inhibition by dexamethasone of the reperfusion phenomena in cardiopulmonary bypass. J Thorac Cardiovasc Surg 1991; 102: 515-25
7. Kaul TK, Fields BL. Leucocyte activation during cardiopulmonary bypass: limitations of the inhibitory mechanisms and strategies. J Cardiovasc Surg (Torino) 2000; 41: 849-62
8. Lockwood TD, Bosmann HB. The use of urinary N-acetyl-β-glucosaminidase in human renal toxicology: II. Partial biochemical characterization and excretion in humans and release from the isolated perfused rat kidney. Toxicol Appl Pharmacol 1979; 49 323-36
9. Westhuyzen J, McGiffin DC, McCarty J, Fleming SJ. Tubular nephrotoxicity after cardiac surgery utilising cardiopulmonary bypass. Clin Chim Acta 1994; 228: 123-32
10. Ip-Yam PC, Murphy S, Baines M, Fox MA, Desmond MJ, Innes PA. Renal function and proteinuria after cardiopulmonary bypass: the effects of temperature and mannitol. Anesth Analg 1994; 78: 842-7
11. Boldt J, Brenner T, Lehmann A, Suttner SW, Kumle B, Isgro F. Is kidney function altered by the duration of cardiopulmonary bypass? Ann Thorac Surg 2003; 75: 906-12
12. Nonoyama A, Katsuda H, Nakahashi M, Uchiyama S, Kubo S. Studies on the massive administration of corticosteroid during open heart surgery. Its effect to renal function. Jpn Circ J 1970; 34: 711-24
13. Gu YJ, Schoen P, Tigchelaar I, et al. Increased neutrophil priming and sensitization before commencing cardiopulmonary bypass in cardiac surgical patients. Ann Thorac Surg 2002: 74 1173-9
14. Tang ATM, Alexiou C, Hsu J, Sheppard SV, Haw MP, Ohri SK. Leukodepletion reduces renal injury in coronary revascularization: a prospective randomized study. Ann Thorac Surg 2002; 74: 372-7
15. Chaney MA, Nikolov MP, Blakeman BP, Bakhos M, Slogoff S. Hemodynamic effects of methylprednisolone in patients undergoing cardiac operation and early extubation. Ann Thorac Surg 1999; 67: 1006-11
16. Chaney MA, Nikolov MP, Blakeman B, Bakhos M, Slogoff S. Pulmonary effects of methylprednisolone in patients undergoing coronary artery bypass grafting and early tracheal extubation. Anesth Analg 1998; 87: 27-33
17. Chaney MA. Corticosteroids and cardiopulmonary bypass. A review of clinical investigations. Chest 2002; 121: 921-31
18. Chaney MA, Darazo-Arvizu RA, Nikolov MP, Blakeman BP, Bakhos M. Methylprednisolone does not benefit patients undergoing coronary artery bypass grafting and early tracheal extubation. J Thorac Cardiovasc Surg 2001; 121: 561-69
19. Tassani P, Richter JA, Baranky A, et al. Does high-dose methylprednisolone in aprotinine-treated patients attenuate the systemic inflammatory response during coronary artery bypass grafting procedures? J Cardiothorac Vasc Anesth 1999; 13: 165-72
20. El Azab SR, Rosseel PMJ, de Lange J, et al. Dexamethasone decreases the pro- to anti-inflammatory cytokine ratio during cardiac surgery. Br J Anaesth 2002; 88: 496-501
21. Mayumi H, Zhang QW, Nakashima A, et al. Synergistic immunosupression caused by high-dose methylprednisolone and cardiopulmonary bypass. Ann Thorac Surg 1997; 63: 129-37
22. Niazi Z, Flodin P, Joyce L, Smith J, Mauer H, Lillehei RC. Effects of glucocorticosteroids in patients undergoing coronary artery bypass surgery. Chest 1979; 76: 262-8
23. McCowen KC, Malhotra A, Bistrian BR. Stress-induced hyperglycemia. Crit Care Clin 2001; 17: 107-24
24. Van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345: 1359-67