Intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-ones and its application to the synthesis of secondary aryl amines

Synlett

Volumn , Issue 14, 2004, Pages 2497-2500

  Fuwa, Haruhiko ^a   Kobayashi, Toshitake ^a,b   Tokitoh, Takashi ^a   Torii, Yukiko ^a   Natsugari, Hideaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Amines; Heterocycles; Medicinal chemistry; Nucleophilic aromatic substitutions; Tandem reactions

Indexed keywords

AROMATIC AMINE; QUINAZOLIN 4 ONE DERIVATIVE; QUINAZOLINONE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; SUBSTITUTION REACTION;

EID: 9644307860     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-834805     Document Type: Article

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