Serum procalcitonin and cerebrospinal fluid cytokines level in children with meningitis

Mediators of Inflammation

Volumn 13, Issue 4, 2004, Pages 269-273

  Taskin, Erdal ^a   Turgut, Mehmet ^a   Kilic, Mehmet ^a   Akbulut, Handan ^a   Aygun, A Denizmen ^a  

^a FIRAT UNIVERSITY   (Turkey)

Author keywords

Children; Interleukin 6; Interleukin 8; Meningitis; Procalcitonin; Tumor necrosis factor alpha

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; PROCALCITONIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL MENINGITIS; CEREBROSPINAL FLUID LEVEL; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; EARLY DIAGNOSIS; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; VIRUS MENINGITIS;

CALCITONIN; CHILD; CHILD, PRESCHOOL; CYTOKINES; DIAGNOSIS, DIFFERENTIAL; EARLY DIAGNOSIS; FEMALE; HUMANS; INFANT; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MENINGITIS, BACTERIAL; MENINGITIS, VIRAL; PROTEIN PRECURSORS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS);

EID: 9644281402     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629350400003084     Document Type: Article

References (31)

1. Baraff LJ, Lee SI, Schriger DL. Outcomes of bacterial meningitis in children: a meta-analysis. Pediatr Infect Dis J 1993; 12: 389-394.
2. Lindquist L, Linne T, Hansson LO, Kalin M, Axelsson G. Value of cerebrospinal fluid analysis in the differential diagnosis of meningitis: a study 710 patients with suspected central nervous system infection. Eur J Clin Microbiol Infect Dis 1988; 7: 374-380.
3. Katz SL. Viral infections of the central nervous. In: Gershon AA, Hotez PJ, eds. Krugman's Infectious Disease Children, St Louis, MO: C.V. Mosby, 1998: 650-666.
4. Marton KI, Gean AD. The spinal tap: a new look at an old test. Ann Intern Med 1986; 104: 840-848.
5. Rotbart HA. Viral meningitis and aseptic menegitis syndrome. In: Scheld WN, Whitley RJ, Durack DT, eds. Infections of the Central Nervous System, 2nd edn, Philadelphia, PA: Lippincott-Raven, 1997: 23-46.
6. Cassady KA, Whitley RJ. Pathogenesis and pathophisysiology of viral infections of the central nervous system. In: Scheld WN, Whitley RJ, Durack DT, eds. Infections of the Central Nervous System, 2nd edn, Philadelphia, PA: Lippincott-Raven, 1997: 7-22.
7. Jacops JW, Lund PK, Potts JT Jr, Bell NH, Habener JF. Procalcitonin is a glycoprotein. J Biol Chem 1981; 256: 2803-2807.
8. Oberhoffer M, Stonans I, Russwurm S, et al. Procalcitonin expression in human peripheral blood mononuclear cells and its modulation by lipopolysaccharides and sepsis-related cytokines in vitro. J Lab Clin Med 1999; 134: 49-55.
9. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-518.
10. Meisner M. PCT-procalcitonin: A New and Innovative Parameter in Diagnosis of Infections, Berlin: BRAHMS Diagnostica, 1996: 14-60.
11. Huber W, Schweigart U, Bottermann P. Failure of PCT to indicate severe fungal infection in two immunodeficient patients. Infection 1997; 25: 377-378.
12. Akalin H, Akdis AC, Mistik R, Helvaci S, Kilicturgay K. Cerebrospinal fluid interleukin-1 beta/interleukin-1 receptor antagonist balance and tumor necrosis factor-alpha concentrations in tuberculous, viral and acute bacterial meningitis. Scand J Infect Dis 1994; 26: 667-674.
13. Mustafa MM, Ramilo O, Saez-Liorens X, Mertsola J, Mc Cracken GH Jr. Role of tumor necrosis factor alpha (cachectin) in experimental and clinical bacterial meningitis. Pediatr Infect Dis J 1989; 8: 907-908.
14. Glimaker M, Kragsbjerg P, Forsgren M, Olcen P. Tumor necrosis factor-alpha (TNF-alpha) in cerebrospinal fluid from patients with meningitis of different etiologies: High levels of TNF-alpha indicate bacterial meningitis. J Infect Dis 1993; 167: 882-889.
15. Kepa L, Adamek B, Stolarz W. Diagnostic value of tumor necrosis factor-alpha (TNF-alpha) determination in cerebrospinal fluid (CSF) in the course of neural infections. Neurol Neuruchir Pol 1998; 32: 533-542
16. Ceyhan M, Kanra G, Ecevit Z, et al. Tumor necrosis factor-alpha and interleukin-1 beta levels in children with bacterial, tuberculous and aseptic meningitis. Turk J Pediatr 1997; 39: 177-184.
17. Gendrel D, Raymond J, Assicot M, et al. Measurement of procalcitonin levels in children with bacterial or viral meningitis. Clin Infect Dis 1997; 24: 1240-1242.
18. Schwarz S, Bertram M, Schwab S, Andrassy K, Hacke W. Serum procalcitonin levels in bacterial and abacterial meningitis. Crit Care Med 2000; 28: 1828-1832.
19. Monneret G, Labaune JM, Isaac C, Bienvenu F, Putet G, Bienvenu J. Procalcitonin and C-reactive protein levels in neonatal infections. Acta Paediatr 1997; 86: 209-212.
20. Viailon A, Zeni F, Lambert C, et al. High sensitivity and specificity of serum procalcitonin levels in adults with bacterial meningitis. Clin Infect Dis 1999; 28: 1313-136.
21. Gendrel D, Bobuon C. Procalcitonin, a marker of bacterial infection. Infection 1997; 25: 133-134.
22. Moller B, Mogensen SC, Wendelboe P, Bendtzen K, Petersen CM. Bioactive and inactive forms of tumor necrosis factor-alpha in spinal fluid from patients with meningitis. J Infect Dis 1991; 163: 886-889.
23. Waage A, Halstensen A, Shalaby R, Brandtzaeg P, Kierulf P, Espevik T. Local production of tumor necrosis factor-alpha, interleukin-1 and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response. J Exp Med 1989; 170: 1859-1867.
24. Houssiau FA, Bukasa K, Sindic CJ, Van Damme J, Van Snick J. Elevated levels of the 26K human hybridoma growth factor (Interleukin 6) in cerebrospinal fluid of patients with acute infection of central nervous system. Clin Exp Immunol 1988; 71: 320-323.
25. Torre D, Zeroli C, Ferraro G, et al. Cerebrospinal fluid levels of IL-6 in patients with acute infections of the central nervous system. Scand J Infect Dis 1992; 24: 787-791.
26. Rusconi F, Parizzi F, Garlaschi L, et al. Interleukin 6 activity in infants and children with bacterial meningitis. The Collaborative Study on Meningitis. Pediatr Infect Dis J 1991; 10: 117-112.
27. Azuma H, Tsuda N, Sasaki K, Okuno A. Clinical significance of cytokine measurement for detection of meningitis. J Pediatr 1997; 131: 463-465.
28. Mastroianni CM, Paoletti F, Rivosecchi RM, et al. Cerebrospinal fluid interleukin 8 in children with purulent bacterial and tuberculous meningitis. Pediatr Infect Dis J 1994; 13: 1008-1010.
29. Ostergard C, Benfield TL, Sellebjerg F, Kronborg G, Lohse N, Lundgren JD. Interleukin-8 in cerebrospinal fluid from patients with septic and aseptic meningitis. Eur J Clin Microbiol Infect Dis 1996; 15: 166-169.
30. Seki T, Joh K, Oh-ishi T. Augmented production of interleukin-8 in cerebrospinal fluid in bacterial meningitis. Immunology 1993; 80: 333-335.
31. Tsai ML, Chen WC, Wang YC, Hung KL. Cerebrospinal fluid interleukin-6, interleukin-8, and tumor necrosis factor-alpha in children with central nervous system infections. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1996; 37: 16-21.