메뉴 건너뛰기




Volumn 26, Issue 6, 2004, Pages 633-637

Association between patient age and gabapentin serum concentration-to-dose ratio: A preliminary multivariate analysis

Author keywords

Age influence; Antiepileptic drugs; Concentration to dose ratio; Dosage influence; Epilepsy; Gabapentin; Therapeutic drug monitoring

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN;

EID: 9644276759     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200412000-00008     Document Type: Article
Times cited : (36)

References (18)
  • 1
    • 0035191623 scopus 로고    scopus 로고
    • Gabapentin: A unique anti-epileptic agent
    • Dougherty JA, Rhoney DH. Gabapentin: a unique anti-epileptic agent. Neurol Res. 2001;23:821-829.
    • (2001) Neurol Res , vol.23 , pp. 821-829
    • Dougherty, J.A.1    Rhoney, D.H.2
  • 2
    • 0008209120 scopus 로고
    • Pediatric clinical pharmacology of antiepileptic drugs: An especial consideration
    • Pippenger CE, Penry JK, Kutt H, eds. New York: Raven Press
    • Pippenger CE. Pediatric clinical pharmacology of antiepileptic drugs: an especial consideration. In: Pippenger CE, Penry JK, Kutt H, eds. Antiepileptic Drugs: Quantitative Analysis and Interpretation. New York: Raven Press; 1978:315-319.
    • (1978) Antiepileptic Drugs: Quantitative Analysis and Interpretation , pp. 315-319
    • Pippenger, C.E.1
  • 3
    • 0027454448 scopus 로고
    • Gabapentin. A review of its pharmacological properties and of its potential in epilepsy
    • Goa KL, Sorkin EM. Gabapentin. A review of its pharmacological properties and of its potential in epilepsy. Drugs. 1993;46:409-427.
    • (1993) Drugs , vol.46 , pp. 409-427
    • Goa, K.L.1    Sorkin, E.M.2
  • 4
    • 0029057902 scopus 로고
    • Gabapentin
    • McLean MJ. Gabapentin. Epilepsia. 1995;36(Suppl 2):73-86.
    • (1995) Epilepsia , vol.36 , Issue.2 SUPPL. , pp. 73-86
    • McLean, M.J.1
  • 5
    • 0033334320 scopus 로고    scopus 로고
    • Gabapentin does not affect antipyrine clearance
    • Allen E, Tsanaclis LM, Wroe SJ, et al. Gabapentin does not affect antipyrine clearance. J Clin Pharmacol. 1999;39:934-935.
    • (1999) J Clin Pharmacol , vol.39 , pp. 934-935
    • Allen, E.1    Tsanaclis, L.M.2    Wroe, S.J.3
  • 6
    • 0028133317 scopus 로고
    • Pharmacokinetics of gabapentin in subjects with various degrees of renal function
    • Blum RA, Comstock TJ, Sica DA, et al. Pharmacokinetics of gabapentin in subjects with various degrees of renal function. Clin Pharmacol Ther. 1994;56:154-159.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 154-159
    • Blum, R.A.1    Comstock, T.J.2    Sica, D.A.3
  • 8
    • 0027402753 scopus 로고
    • A saturable transport mechanism in the intestinal absoprtion of gabapentin is the underlying cause of lack of proportionality between increasing dose and drug levels in plasma
    • Stewart BH, Kugler AR, Thompson PR, et al. A saturable transport mechanism in the intestinal absoprtion of gabapentin is the underlying cause of lack of proportionality between increasing dose and drug levels in plasma. Pharm Res. 1993;10:276-281.
    • (1993) Pharm Res , vol.10 , pp. 276-281
    • Stewart, B.H.1    Kugler, A.R.2    Thompson, P.R.3
  • 9
    • 0030776298 scopus 로고    scopus 로고
    • Gabapentin monotherapy, II: A 26-week, double blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory compfex partial or secondarily generalized seizures
    • The US Gabapentin Study Group 82/83
    • Beydoun A, Fischer J, Labar DR, et al. Gabapentin monotherapy, II: a 26-week, double blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory compfex partial or secondarily generalized seizures. The US Gabapentin Study Group 82/83. Neurology. 1997;49:746-752.
    • (1997) Neurology , vol.49 , pp. 746-752
    • Beydoun, A.1    Fischer, J.2    Labar, D.R.3
  • 10
    • 0030870483 scopus 로고    scopus 로고
    • Gabapentin monotherapy, I: An 8-day, double blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures
    • The US Gabapentin Study Group 88/89
    • Bergey GK, Morris HH, Rosenfeld W, et al. Gabapentin monotherapy, I: An 8-day, double blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 88/89. Neurology. 1997;49:739-745.
    • (1997) Neurology , vol.49 , pp. 739-745
    • Bergey, G.K.1    Morris, H.H.2    Rosenfeld, W.3
  • 11
    • 0035031375 scopus 로고    scopus 로고
    • Single-dose gabapentin pharmacokinetics and safety in healthy infants and children
    • Haig GM, Bockbrader HN, Wesche DL, et al. Single-dose gabapentin pharmacokinetics and safety in healthy infants and children. J Clin Pharmacol. 2001;41:507-514.
    • (2001) J Clin Pharmacol , vol.41 , pp. 507-514
    • Haig, G.M.1    Bockbrader, H.N.2    Wesche, D.L.3
  • 12
    • 0035653968 scopus 로고    scopus 로고
    • Population pharmacokinetics of gabapentin in infants and children
    • Quellet D, Bockbrader HN, Wesche DL, et al. Population pharmacokinetics of gabapentin in infants and children. Epilepsy Res. 2001;47:229-241.
    • (2001) Epilepsy Res , vol.47 , pp. 229-241
    • Quellet, D.1    Bockbrader, H.N.2    Wesche, D.L.3
  • 13
    • 12244311179 scopus 로고    scopus 로고
    • Plasma gabapentin concentrations in children with epilepsy: Influence of age, relationship with dosage, and preliminary observations on correlation with clinical response
    • Gatti G, Ferrari AR, Guerrini R, et al. Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response. Ther Drug Monit. 2003;25:54-60.
    • (2003) Ther Drug Monit , vol.25 , pp. 54-60
    • Gatti, G.1    Ferrari, A.R.2    Guerrini, R.3
  • 14
    • 0032958091 scopus 로고    scopus 로고
    • Effects of age and gender on single-dose pharmacokinetics of gabapentin
    • Boyd RA, Turck D, Abel RB, et al. Effects of age and gender on single-dose pharmacokinetics of gabapentin. Epilepsia. 1999;40:474-479.
    • (1999) Epilepsia , vol.40 , pp. 474-479
    • Boyd, R.A.1    Turck, D.2    Abel, R.B.3
  • 15
    • 0023206481 scopus 로고
    • Analysis of taurine in blood plasma of epileptic patients using an improved isocratic HPLC method for amino acids
    • Eslami M, Stuart JD, Dean RW. Analysis of taurine in blood plasma of epileptic patients using an improved isocratic HPLC method for amino acids. J Liq Chromatogr. 1987;10:977-995.
    • (1987) J Liq Chromatogr , vol.10 , pp. 977-995
    • Eslami, M.1    Stuart, J.D.2    Dean, R.W.3
  • 16
    • 0026006513 scopus 로고
    • Relationship between platelet and brain GABA-transaminase inhibition by single and multiple doses of vigabatrin in rats
    • Valdizàn EM, Armijo JA. Relationship between platelet and brain GABA-transaminase inhibition by single and multiple doses of vigabatrin in rats. Epilepsia. 1991;32:735-742.
    • (1991) Epilepsia , vol.32 , pp. 735-742
    • Valdizàn, E.M.1    Armijo, J.A.2
  • 17
    • 0023475125 scopus 로고
    • Lamotrigine a new anticonvulsant: Pharmacokinetics in normal humans
    • Cohen AF, Land GS, Breimer DD, et al. Lamotrigine a new anticonvulsant: pharmacokinetics in normal humans. Clin Pharmacol Ther. 1987;42:535-541.
    • (1987) Clin Pharmacol Ther. , vol.42 , pp. 535-541
    • Cohen, A.F.1    Land, G.S.2    Breimer, D.D.3
  • 18
    • 0029871541 scopus 로고    scopus 로고
    • Three-year efficacy and tolerability of add-on lamotrigine in treatment-resistant epileptic children
    • Herranz JL, Arteaga R, Armijo JA. Three-year efficacy and tolerability of add-on lamotrigine in treatment-resistant epileptic children. Clin Drug Invest. 1996;11:214-223.
    • (1996) Clin Drug Invest , vol.11 , pp. 214-223
    • Herranz, J.L.1    Arteaga, R.2    Armijo, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.