Damage to the hippocampal formation does not disrupt representational flexibility as measured by a novelty transfer test

Behavioral Neuroscience

Volumn 118, Issue 6, 2004, Pages 1427-1432

  Driscoll, Ira ^a,c   Sutherland, Robert J ^a,c   Prusky, Glen T ^a,c   Rudy, Jerry W ^b  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BRAIN FUNCTION; BRAIN INJURY; CONTROLLED STUDY; DECISION MAKING; FEMALE; HIPPOCAMPUS; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; LEARNING; NONHUMAN; RAT; SPATIAL ORIENTATION; TASK PERFORMANCE; TRAINING; VISUAL DISCRIMINATION;

ANIMALS; BEHAVIOR, ANIMAL; DISCRIMINATION LEARNING; EXCITATORY AMINO ACID AGONISTS; EXPLORATORY BEHAVIOR; FEMALE; HIPPOCAMPUS; N-METHYLASPARTATE; RATS; RATS, INBRED F344; SPACE PERCEPTION; TRANSFER (PSYCHOLOGY);

EID: 9644272692     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.118.6.1427     Document Type: Article

References (22)

1. Dusek, J. A., & Eichenbaum, H. (1997). The hippocampus and memory for orderly stimulus relations. Proceedings of the National Academy of Sciences, USA, 94, 7109-7114.
2. Eichenbaum, H. (1992). The hippocampal system and declarative memory in animals. Journal of Cognitive Neuroscience, 4, 217-231.
3. Eichenbaum, H., Mathews, P., & Cohen, N. J. (1989). Further studies of hippocampal representation during odor discrimination learning. Behavioral Neuroscience, 103, 1207-1216.
4. Frank, M. J., Rudy, J. W., & O'Reilly, R. C. (2003). Transitivity, flexibility, conjunctive representations and the hippocampus: II. A computational analysis. Hippocampus, 13, 299-312.
5. Hirsch, R. (1974). The hippocampus and contextual retrieval of information from memory. A theory. Behavioral Biology, 12, 421-444.
6. McNaughton, B. L., & Morris, R. G. M. (1987). Hippocampal synaptic enhancement and information storage within a distributed memory system. Trends in Neurosciences, 10, 408-415.
7. Mishkin, M., Malamut, B., & Bachevalier, J. (1984). Memories and habits: Two neural systems. In G. Lynch, J. L. McGaugh, & N. Weinberger (Eds.), Biology of memory (pp. 65-77). New York: Academic Press.
8. Morris, R. G. M. (1981). Spatial localization does not require the presence of local cues. Learning and Motivation, 12, 239-260.
9. Morris, R. G. M., Garrud, P., Rawlins, J. N. P., & O'Keefe, J. (1982, June 24). Place navigation impaired in rats with hippocampal lesions. Nature, 297, 681-683.
10. O'Keefe, J., & Nadel, L. (1978). The hippocampus as a cognitive map. Oxford, England: Clarendon Press.
11. O'Reilly, R. C., & Rudy, J. W. (2001). Conjunctive representations in learning and memory: Principles of cortical and hippocampal function. Psychological Review, 108, 311-345.
12. Paxinos, G., & Watson, C. (1982). The rat brain in stereotaxic coordinates. New York: Academic Press.
13. Prusky, G. T., West, P. W. R., & Douglas, R. M. (2000). Behavioral assessment of visual acuity in mice and rats. Vision Research, 40, 2201-2209.
14. Rudy, J. W., Huff, N., & Matus-Amat, P. (in press). Understanding contextual fear conditioning: Insights from a two process model. Neuroscience & Biobehavioral Reviews.
15. Rudy, J. W., & O'Reilly, R. C. (2001). Conjunctive representations, the hippocampus, and contextual fear conditioning. Cognitive, Affective, and Behavioral Neuroscience, 1, 66-82.
16. Rudy, J. W., & Sutherland, R. J. (1994). The memory coherence problem, configurai associations and the hippocampal system. In D. Schacter & E. Tulving (Eds.), Memory systems (pp. 119-147). Cambridge, MA: MIT Press.
17. Rudy, J. W., & Sutherland, R. J. (1995). Configural association theory and the hippocampal formation: An appraisal and reconfiguration. Hippocampus, 5, 375-389.
18. Squire, L. R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychological Review, 99, 195-231.
19. Sutherland, R. J., Kolb, B., & Whishaw, I. Q. (1982). Spatial mapping: Definitive disruption by hippocampal or frontal cortical damage in rat. Neuroscience Letters, 31, 271-276.
20. Sutherland, R. J., & Rudy, J. W. (1989). Configural association theory: The role of the hippocampal formation in learning, memory, and amnesia. Psychobiology, 17, 129-144.
21. Tyler, T. J., & DiScenna, P. (1986). The hippocampus memory indexing theory. Behavioral Neuroscience, 100, 147-152.
22. Van Elzakker, M., O'Reilly, R. C., & Rudy, J. W. (2003). Transitivity, flexibility, conjunctive representations, and the hippocampus: I. An empirical analysis. Hippocampus, 13, 292-298.