N 4-alkyloxycarbonyl derivatives of cytosine: Physicochemical characterisation, and cytosine regeneration rates and release from alginic acid gels

European Journal of Pharmaceutical Sciences

Volumn 23, Issue 4-5, 2004, Pages 337-345

  Petersson, Karsten ^a   Pedersen, Brian Thoning ^a   Stærk, Dan ^a   Krogfelt, Karen A ^b   Larsen, Claus ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

Cytosine; Helicobacter pylori; Hydrolysis; Lipophilicity; N alkyloxycarbonyl derivatives; Prodrug; Release; Solubility; Ulcus

Indexed keywords

ALGINIC ACID; CYTOSINE DERIVATIVE; N 4 ADAMANTYLOXYCARBONYLCYTOSINE; N 4 BENZYLOXYCARBONYLCYTOSINE; N 4 BUTYLOXYCARBONYLCYTOSINE; N 4 ETHYLOXYCARBONYLCYTOSINE; N 4 HEXYLOXYCARBONYLCYTOSINE; N 4 ISOBUTYLOXYCARBONYLCYTOSINE; N 4 METHYLCARBONYLCYTOSINE; N 4 NEOPENTYLOXYCARBONYLCYTOSINE; N 4 OCTYLOXYCARBONYLCYTOSINE; PEPSIN A; UNCLASSIFIED DRUG; URACIL; CYTOSINE; DRUG DERIVATIVE; GLUCURONIC ACID; HEXURONIC ACID;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG DEGRADATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG SYNTHESIS; HELICOBACTER PYLORI; HYDROLYSIS; NONHUMAN; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STOMACH; SWINE; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; GEL;

ALGINATES; ANIMALS; CHEMISTRY, PHYSICAL; CYTOSINE; DELAYED-ACTION PREPARATIONS; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; SWINE;

EID: 9644270221     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2004.08.007     Document Type: Article

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