Hyperphosphorylation of extracellular regulated kinase 2 (ERK2) and inhibition of JNK2 phosphorylation are associated with increased S-phase during transformation of Syrian hamster embryo cells by Malachite Green

Cell Biology International

Volumn 28, Issue 12, 2004, Pages 875-883

  Bose, Bipasha ^a   Gour, Rekha R ^b   Motiwale, Leena ^a   Gupta, Sanjay ^a   Rao, K V K ^a  

^a CANCER RESEARCH INSTITUTE   (India)

^b Adv Ctr Treatm Res Educ C

Author keywords

Cell cycle; Extracellular regulated kinases; JUN N terminal kinases; Malachite Green (MG); p38 Kinase; Transformation

Indexed keywords

MALACHITE GREEN; MITOGEN ACTIVATED PROTEIN KINASE 1;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; MALIGNANT TRANSFORMATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SYRIAN HAMSTER; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; CARCINOGENS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CRICETINAE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-1; MESOCRICETUS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 9; NEOPLASMS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; ROSANILINE DYES; S PHASE; UP-REGULATION;

CRICETINAE; MAMMALIA; MESOCRICETUS AURATUS; SIPROETA STELENES;

EID: 9644270180     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2004.09.001     Document Type: Article

References (48)

1. D.W. Abbott, and J.T. Holt Mitogen activated protein kinase kinase activation is essential for progression through G2/M checkpoint arrest in cells exposed to ionising radiation J Biol Chem 274 1999 2732 2742
2. J.L. Allen, J.E. Gofus, and J.R. Metmertz Determination of Malachite Green residues in eggs, fry and adult muscle tissue of rainbow trout (Oncorhynchus mykiss) J AOAC Int 77 1994 553 557
3. R.V. Bhat, and P. Mathur Changing scenario of food colours in India Curr Sci 74 1998 198 202
4. A. Brunet, D. Roux, P. Leonard, S. Dowd, S. Keyse, and J. Pouyssegur Nuclear translocation of p42/44 mitogen activated protein kinase is required for growth factor induced gene expression and cell cycle entry EMBO J 18 1999 664 674
5. v integrin, p38 mitogen activated protein kinase and urokinase plasminogen activator are functionally linked in invasive breast cancer cells J Biol Chem 276 2001 47901 47905
6. E.A. Collisson, A. De, H. Suzuki, S.S. Gambhir, and M.S. Kolodney Treatment of metastatic melanoma with orally available inhibitor of Ras-Raf MAP kinase cascade Cancer Res 63 2003 5669 5673
7. S. Cowley, H. Paterson, P. Kemp, and C.J. Marshall Activation of MAP kinase kinase is necessary and sufficient for PC 12 differentiation and for transformation of NIH 3T3 cells Cell 77 1994 841 852
8. R.J. Davis Signal transduction by the JNK group of MAP kinases Cell 103 2000 239 252
9. D.T. Denhardt Signal transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling Biochem J 318 1996 729 747
10. B. Derijard, M. Hibi, I.H. Wu, T. Barrett, B. Su, and T. Deng JNK 1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-JUN activation domain Cell 76 1994 1025 1037
11. J.D. Han, L. Lee, L. Bibbs, and R.J. Ulevitch A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells Science 265 1994 808 811
12. D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
13. F. Hochholdinger, G. Baier, A. Nogalo, B. Baur, H.H. Grunicke, and F. Uberall Novel membrane targeted ERK-1 and ERK-2 chimeras that act as dominant negative, isotype specific mitogen activated protein kinase inhibitors of Ras-Raf mediated transcriptional activation of c fos in NIH 3T3 cells Mol Cell Biol 19 1999 8052 8065
14. M. Hocker, R.J. Henihan, S. Rosenwicz, E.O. Riecken, Z. Zhang, and T. Koh Gastrin and phorbol 12-myristate 13 acetate regulate the human histidine decarboxylase promoter through Raf dependent activation of extracellular signal regulated kinase related signalling pathways in gastric cancer cells J Biol Chem 272 1997 27015 27024
15. C. Huang, W.Y. Ma, M.R. Young, N.H. Colburn, and Z. Zong Shortage of mitogen activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells Proc Natl Acad Sci U S A 95 1998 156 161
16. T. Hunter Oncoprotein networks Cell 88 1997 333 346
17. R. Johnson, A.M. Gardner, K.M. Diener, C.A. Large Carter, J. Gleamy, and M.B. Jarpe Signal transduction pathways regulated by mitogen activated/extracellular response kinase kinase kinase induce cell death J Biol Chem 271 1996 3229 3237
18. R. Johnson, B. Spiegelman, D. Hanahan, and R. Wisdom Cellular transformation and malignancy induced by ras require c jun Mol Cell Biol 16 1996 4504 4511
19. C. Kahan, K. Seuwen, S. Meloche, and J. Pouyssegur Coordinated biphasic activation of p44 mitogen activated protein kinase and S6 kinase by growth factors in hamster fibroblasts J Biol Chem 267 1992 13369 13375
20. T. Kakunaga H.H. Hiall J.D. Watson J.A. Wilson The origin of human cancer 1977 Cold Spring Harbor New York 1537 1548
21. T. Kakunaga Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens Proc Natl Acad Sci U S A 75 1978 1334 1338
22. M. Kawada, S. Yamagoe, Y. Murakami, K. Suzuki, S. Mizuno, and Y. Uehara Induction of p27 kip1 degradation and anchorage independence by Ras through the MAP kinase signalling pathway Oncogene 15 1997 629 637
23. E. Kiyokawa, S. Takai, M. Tanaka, T. Iwase, M. Suzuki, and Y.Y. Xing Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors Cancer Res 54 1994 3645 3650
24. J.M. Kyriakis, P. Banerjee, E. Nikolakaki, T. Dai, E.A. Rubie, and M.F. Ahamad The stress activated protein kinase subfamily of c JUN kinases Nature 369 1994 156 160
25. J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur Cyclin D1 overexpression is regulated positively by the p42/44 MAPK and negatively by the p38/HOG MAPK pathway J Biol Chem 271 1996 20608 20616
26. D.M. Mahudawala, A.A. Redkar, A. Wagh, B. Gladstone, and K.V.K. Rao Malignant transformation of Syrian hamster embryo (SHE) cells in culture by Malachite Green: an agent of environmental importance Indian J Exp Biol 37 1999 904 918
27. D.M. Mahudawala, A. Redkar, and K.V.K. Rao The malignant transformation of Syrian hamster embryo (SHE) cells in primary culture by Malachite Green: the transformation is associated with enhanced vimentin phosphorylation, PCNA expression and Brdu incorporation Cell Mol Biol Lett 5 2000 75 89
28. S.J. Mansour, W.T. Matten, A.S. Herman, J.M. Candia, S. Rong, and K. Fukasawa Transformation of mammalian cells by constitutively active MAP kinase kinase Science 265 1994 966 970
29. S. Meloche, G. Pages, and J. Pouyssegur Functional expression and growth factor activation of an epitope tagged p44 mitogen activated protein kinase p44 MAPK Mol Biol Cell 3 1992 63 71
30. K. Nakamura, T. Shirai, S. Morishita, S. Uchida, K. Saekin-Miura, and F. Makishima p38 mitogen activated protein kinase functionally contributes to chondrogenesis by growth/differentiation factor 5 in ATDC 5 cells Exp Cell Res 250 1999 351 363
31. K. Ono, and H. Jiahuai The p38 signal transduction pathway activation and function Cell Signal 12 2000 1 13
32. A. Panandiker, C. Fernandes, and K.V.K. Rao The cytotoxic properties of malachite green are associated with the increased demethylase, arylhydrocarbon hydroxylase and lipid peroxidation in primary culture of Syrian hamster embryo cells Cancer Lett 67 1992 91 101
33. A. Panandiker, G.B. Maru, and K.V.K. Rao Dose response effect of malachite green on free radical formation, lipid peroxidation and DNA damage in Syrian hamster embryo cells and their modulation by antioxidants Carcinogenesis 15 1994 2445 2448
34. K.V.K. Rao Comparative cytotoxic effects of the non permitted food colouring agents metanil yellow, orange II, rhodamine B and malachite green on hamster dermal and C3H/10T1/2 fibroblasts Bombay Hospital J 32 1989 61 65
35. K.V.K. Rao Inhibition of DNA synthesis in primary rat hepatocyte cultures by malachite green; a new liver tumor promoter Toxicol Lett 81 1995 107 113
36. K.V.K. Rao, D.M. Mahudawala, and A. Redkar Malignant transformation of Syrian hamster embryo (SHE) cells in primary culture by malachite green: transformation is associated with abrogation of G2/M checkpoint control Cell Biol Int 22 1998 581 589
37. M.J. Robinson, and M.H. Cobb Mitogen activated protein kinase pathways Curr Opin Cell Biol 9 1997 180 186
38. K. Satyamoorthy, Gang Li, M.R. Gerrero, M.S. Boose, P. Volpe, and B.C. Weber Constitutive mitogen activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation Cancer Res 63 2003 756 759
39. B. Salh, A. Marotta, R. Wagey, M. Sayed, and S. Pelech Dysregulation of phosphatidylinositol 3 kinase and downstream effectors in human breast cancer Int J Cancer 98 2002 148 154
40. R.E. Shackelford, W.K. Kaufman, and R.S. Paules Cell cycle checkpoint mechanisms and geno toxic stress Environ Health Perspect 107 1999 5 23
41. R.E. Shackelford, W.K. Kaufmann, and R.S. Paules Oxidative stress and cell cycle checkpoint function Free Radic Biol Med 28 2000 1387 1404
42. M. Sundarrajan, S. Gupta, and K.V.K. Rao Overexpression of cyclin D1 is associated with the decondensation of chromatin during DEN-induced sequential hepatocarcinogenesis Cell Biol Int 26 2002 699 706
43. S.E.F. Tran, T.H.E. Homstrom, M. Ahonem, K. Veli-Matti, and J.E. Eriksson MAPK/ERK overrides the apoptotic signalling from Fas, TNF and TRAIL receptors J Biol Chem 276 2001 16484 16490
44. R. Triesman Regulation of transcription by MAP kinase cascades Curr Opin Cell Biol 8 1996 205 215
45. C. Wang, D. Thor, D.H. Moore, O.Y. Zha, R. Kerschman, and R. Stern The overexpression of RHAMM, a hyaluronate binding protein that regulates ras signalling, correlates with overexpression of mitogen activated protein kinase and is a significant parameter in breast cancer progression Clin Cancer Res 4 1998 567 576
46. WHO, World Health Organisation. Technical report series No. 309, Geneva; 1965.
47. Windholz M, Budhavani S, Blumetti RF, Otterbein ES. In: The Merck index. 10th ed. Rahway NJ; 1983. p. 813.
48. J. Xing, J.M. Kornhauser, Z. Xia, E.A. Thiele, and M.E. Greenberg Nerve growth factor activates extracellular signal regulated kinase and p38 mitogen activated protein kinase pathways to stimulate CREB serine 133 phosphorylation Mol Cell Biol 18 1998 1946 1955