Immunohistochemical study of hnRNP B1 in the postmortem temporal cortices of patients with Alzheimer's disease

Neuroscience Research

Volumn 50, Issue 4, 2004, Pages 481-484

  Ishikawa, Masanori ^a   Mizukami, Katsuyoshi ^a   Iwakiri, Masahiko ^a   Kamma, Hiroshi ^a   Ikonomovic, Milos D ^b   Dekosky, Steven T ^b   Asada, Takashi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Alzheimer's disease; Amyloid beta protein; hnRNP; Immunohistochemistry; Neurofibrillary tangle

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN;

AGED; ALZHEIMER DISEASE; ANTIBODY LABELING; ARTICLE; AUTOPSY; BRAIN SLICE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NERVE CELL; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPORAL CORTEX;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BIOLOGICAL MARKERS; DISEASE PROGRESSION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEUROFIBRILLARY TANGLES; NEURONS; POSTMORTEM CHANGES; RNA PROCESSING, POST-TRANSCRIPTIONAL; TEMPORAL LOBE;

EID: 9644264003     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2004.08.013     Document Type: Article

References (14)

1. H. Braak, and E. Braak Neuropathological staging of Alzheimer-related changes Acta Neuropathol. (Berl.) 82 1991 239 259
2. G. Dreyfuss, M.J. Matunis, S. Piñol-Roma, and C.G. Burd hnRNP proteins and the biogenesis of mRNA Annu. Rev. Biochem. 62 1993 289 321
3. H. Kamma, D.S. Portman, and G. Dreyfuss Cell type-specific expression of hnRNP proteins Exp. Cell. Res. 221 1995 187 196
4. H. Kamma, H. Horiguchi, L. Wan, M. Matsui, M. Fujiwara, M. Fujimoto, T. Yazawa, and G. Dreyfuss Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms Exp. Cell. Res. 246 1999 399 411
5. H. Kamma, M. Fujimoto, M. Fujiwara, M. Matsui, H. Horiguchi, M. Hamasaki, and H. Satoh Interaction of hnRNP A2/B1 isoforms with telomeric ssDNA and the in vitro function Biochem. Biophys. Res. Commun. 280 2001 625 630
6. M.P. Mattson Emerging neuroprotective strategies for Alzheimer's disease: dietry restriction, telomerase activation, and stem cell therapy Exp. Gerontol. 35 2000 489 502
7. A receptor β2/3 subunits in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes Exp. Neurol. 147 1997 333 345
8. K. Mizukami, H. Kamma, M. Ishikawa, and G. Dreyfuss Immunohistochemical study of the hnRNP A2 and B1 in the rat forebrain NeuroReport 11 2000 3099 3102
9. S. Piñol Roma, and G. Dreyfuss Shuttling of premature mRNA bindings proteins between nucleus and cytoplasm Nature 355 1992 730 732
10. N.A. Simonian, and B.T. Hyman Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation J. Neuropathol. Exp. Neurol. 53 1994 508 512
11. N.A. Simonian, and B.T. Hyman Functional alterations in neuronal circuits in Alzheimer's disease Neurobiol. Aging 16 1995 305 309
12. R.W.H. Verwer, K.A. Jansen, A.A. Sluiter, C.W. Pool, W. Kamphorst, and D.F. Swaab Decreased hippocampal metabolic activity in Alzheimer patients is not reflected in the immunoreactivity of cytochrome oxidase subunits Exp. Neurol. 163 2000 440 451
13. C.L. Weaver, M. Espinoza, Y. Kress, and P. Davies Conformational change as one of the earliest alterations of tau in Alzheimer's disease Neurobiol. Aging 5 2000 719 727
14. H. Zhu, W. Fu, and M.P. Mattson The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis J. Neurochem. 75 2000 117 124