Study on molecular epidemiology of the α-thalassemias in Liuzhou City, Guangxi Autonomous Region, China

Hemoglobin

Volumn 28, Issue 4, 2004, Pages 325-333

  Cai, Ren ^a   Liu, Jingzhong ^b   Wang, Lirong ^b   Liang, Xin ^a   Xiao, Bai ^b   Su, Liu ^a   Zhou, Yan ^b   Pan, Lizhen ^a  

^a Women and Children's Hospital   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Thalassemia (thal) epidemiology; Hb H disease; Multiplex polymerase chain reaction (mPCR)

Indexed keywords

ALPHA GLOBIN; HEMOGLOBIN H;

ALPHA THALASSEMIA; ARTICLE; BLOOD SAMPLING; CHINA; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE CLASSIFICATION; DISEASE SEVERITY; DNA DETERMINATION; EPIDEMIOLOGICAL DATA; GENE DELETION; GENE FREQUENCY; GENETIC COUNSELING; GENOTYPE; HEMOGLOBIN ANALYSIS; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN SCREENING; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PREVALENCE; UMBILICAL CORD BLOOD;

ALPHA-THALASSEMIA; CHINA; EPIDEMIOLOGY, MOLECULAR; FEMALE; GENOTYPE; GLOBINS; HEMOGLOBINS, ABNORMAL; HUMANS; INCIDENCE; INFANT, NEWBORN; MALE; POLYMERASE CHAIN REACTION;

EID: 9644257069     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-200037743     Document Type: Article

References (11)

1. Chinese Hemoglobin Research Collaboration Groups. A research on hemoglobinopathy among 600,000 population in 20 of provinces, municipalities directly under the Central Government and Autonomous Regions. Chinese J Med 1983; 63(6):382-385.
2. Zeng YT, Huang SZ, Chen MJ. The types and distribution of α-thalassemia-2 in China. Hemoglobin 1988; 12(5&6):455-458.
3. Liu JZ, Ou CY, Wang LR, Xiao B, Huang LJ, Chen LC. Detection of three common deletional determinants of α-thalassemia in Southern China by a single-tube multiplex polymerase chain reaction method. Hemoglobin 2004; 28(1):39-44.
4. Blin N, Stafford DW. A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 1976; 3(9):2303-2308.
5. Zhao SP, Zhang ZJ, You J, Yang YH, Guo F. The establishment and application of genomic DNA extraction from peripheral blood. Chinnese J Med Genet 1999; 16(6):305-396.
6. Ko TM, Tseng LH, Hsieh FJ, Hsu PM, Lee TY. Carrier detection and prenatal diagnosis of α-thalassemia of Southeast Asian deletion by polymerase chain reaction. Hum Genet 1992; 88(3):245-248.
7. Liu JZ, Zhou J, Wang LR, Zhou Y. Study on new techniques for genetic diagnosis of deletional α-thalassemia. Chin J Hematol 2001; 22(4):193-196.
8. Chan V, Yam I, Chen FE, Chan TK. A reverse dot-blot method for rapid detection of non-deletion α thalassemia. Br J Haematol 1999; 104(3):513-515.
9. Zhang JZ, Xu XM, Ma WF, Shan YX. Detection of α-thalassemia mutations in Chinese by using reverse dot hybridization method. J First Milit Med Univ 1999; 13(1):1-5.
10. Liang R, Liang X, Jiang NH, Wen XJ, Zhao JB, Nechtman JF, Stoming TA, Huisman THJ. α and β thalassemia among Chinese children in GuangXi Province, P.R. China: molecular and haematolagical characterization. Br J Haematol 1994; 86(2):351-354.
11. Chen J, Sun Q, Chen MY, Ren ZR, Huang SZ. Analysis of β globin genes of 124 Hb H patients. Shanghai Med 1999; 22(2):83-86.