Sparging and agitation-induced injury of cultured animal cells: Do cell- to-bubble interactions in the bulk liquid injure cells?

Biotechnology and Bioengineering

Volumn 51, Issue 4, 1996, Pages 399-409

  Michaels, James D ^a,b   Mallik, Ameet K ^a,c   Papoutsakis, Eleftherios T ^a  

^a Northwestern University   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c ABBOTT LABORATORIES   (United States)

Author keywords

agitation; bubble aeration; bubble coalescence and breakup; cell culture; cell damage

Indexed keywords

ANIMAL CELL CULTURE; BIOREACTORS; BUBBLES (IN FLUIDS); COALESCENCE; FOAMS; GROWTH KINETICS; MIXING;

AGITATION; BUBBLE AERATION; BUBBLE BREAKUP; BUBBLE COALESCENCE; CELL DAMAGE; OXYGENATION; SPARGING;

CELLS;

AERATION; ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL GROWTH; CELL VIABILITY; NONHUMAN; OXYGENATION; SURFACE PROPERTY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 9544254971     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960820)51:4<399::AID-BIT3>3.3.CO;2-X     Document Type: Article

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