Structural determinants of nucleotide coenzyme specificity in the distinctive dinucleotide binding fold of HMG-CoA reductase from Pseudomonas mevalonii

Biochemistry

Volumn 35, Issue 37, 1996, Pages 11945-11950

  Friesen, Jon A ^a   Martin Lawrence, C ^b,c   Stauffacher, Cynthia V ^b   Rodwell, Victor W ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ALANINE; AMINO ACID; ARGININE; ASPARAGINE; ASPARTIC ACID; BACTERIAL ENZYME; DINUCLEOTIDE; GLYCINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LEUCINE; LYSINE; MEVALONIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NUCLEOTIDE; SERINE; THREONINE;

ACYLATION; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRICETINAE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXYMETHYLGLUTARYL COA REDUCTASES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAD; NADP; OXIDATION-REDUCTION; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS; RATS; RECOMBINANT PROTEINS; SEA URCHINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); FELIS CATUS; PSEUDOMONAS; PSEUDOMONAS MEVALONII;

EID: 9544233649     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9609937     Document Type: Article

References (26)

1. Beach, M., & Rodwell, V. W. (1989) J. Bacteriol. 171, 2994-3001.
2. Bischoff, K. M., & Rodwell, V. W. (1996) J. Bacteriol. 178, 19-23.
3. Bocanegra, J., Scrutton, N., & Perham, R. (1993) Biochemistry 32, 2737-2740.
4. Brown, W. E., & Rodwell, V. W. (1980) in Dehydrogenases Requiring Nicotinamide Coenzymes (Jeffery, J., Ed.) pp 232-272, Birkhauser Verlag, Basel.
5. Cabrera, J. A., Bolds, J., Shields, P. E., Havel, C. M., & Watson, J. A. (1986) J. Biol. Chem. 261, 3578-3583.
6. Chen, R., Greer, A., & Dean, A. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 11666-11670.
7. Chen, Z., Lee, W., & Chang, S. (1991) Eur. J. Biochem. 202, 263-267.
8. Clermont, S., Corbier, C., Mely, Y., Gerard, D., Wonacott, A., & Branlant, G. (1993) Biochemistry 32, 10178-10184.
9. Devereux, J. P., Haeberli, P., & Smithies, O. (1984) Nucleic Acids Res. 12, 387-395.
10. Fan, F., Lorenzen, J., & Plapp, B. (1991) Biochemistry 30, 6397-6401.
11. Feeney, R., Clarke, A. R., & Holbrook, J. J. (1990) Biochem. Biophys. Res. Commun. 166, 667-672.
12. Gill, J. F., Jr., Beach, M. J., & Rodwell, V. W. (1985) J. Biol. Chem. 260, 9393-9398.
13. Grimshaw, C., Matthews, D., Varughese, K., Skinner, M., Xuong, N., Bray, B., Hoch, J., & Whiteberg, J. (1992) J. Biol. Chem. 267, 15334-15339.
14. Kim, J. P., & Wu, J. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 6677-6681.
15. Lawrence, C. M., Rodwell, V. W., & Stauffacher, C. V. (1995) Science 268, 1758-1762.
16. Mikaelian, I., & Sergeant, A. (1992) Nucleic Acids Res. 20, 376.
17. Nishiyama, M., Birktoft, J. J., & Teruhiko, B. (1993) J. Biol. Chem. 268, 4656-4660.
18. Rodwell, V. W., Nordstrom, J. L., & Mitschelen, J. J. (1976) Adv. Lipid Res. 14, 1-74.
19. Rossmann, M., Liljas, A., Branden, C.-I., & Banaszak, L. (1975) Enzymes 11, 61-102.
20. Rowland, P., Basak, A. K., Cover, S., Levy, H. R., & Adams, M. J. (1994) Structure 2, 1073-1087.
21. Sambrook, J., Fritsch, E. F., & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Press, Cold Spring Harbor, NY.
22. Sanger, F., Nicklen, S., & Coulson, A. R. (1977) Proc. Natl. Acad. Sci U.S.A. 74, 5463-5467.
23. Sayle, R. (1995) RasMol v2.6β, obtained via anonymous ftp from ftp.dcs.ed.ac.uk/pub/rasmol/.
24. Scrutton, N. S., Berry, A., & Perham, R. N. (1990) Nature 343, 38-43.
25. Wang, Y., Darnay, B. G., & Rodwell, V. W. (1990) J. Biol. Chem. 265, 21634-21641.
26. Yaoi, T., Miyazaki, K., & Oshima, T. (1994) FEBS Lett. 355, 171-172.