Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines

Blood

Volumn 88, Issue 6, 1996, Pages 2250-2258

  Georgii Hemming, Patrik ^a   Jernberg Wiklund, Helena ^a   Ljunggren, Östen ^a   Nilsson, Kenneth ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SOMATOMEDIN C;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

EID: 9544221630     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.6.2250.bloodjournal8862250     Document Type: Article

References (54)

1. Klein B: Cytokine, cytokine receptors, transduction signals, and oncogenes in human multiple myeloma. Semin Hematol 32:4, 1995
2. Klein B, Zhang XG, Jourdan M: Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 73:517, 1989
3. Nilsson K, Jernberg H, Pettersson M: IL-6 as a growth factor for human MM cells. A short overview. Curr Top Microbiol Immunol 166:3, 1990
4. Jernberg H, Pettersson M, Kishimoto T, Nilsson K: Heterogeneity in response to interleukin 6 (IL-6), expression of IL-6 and IL-6 receptor mRNA in a panel of established human multiple myeloma cell lines. Leukemia 5:255, 1991
5. Klein B, Wijdenes J, Zhang XG, Jourdan M, Boiron JM, Brochier J, Liautard J, Merlin M, Clement C, Morel-Fournier B, Lu ZY, Mannoni P, Sany J, Bataille R: Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78:1198, 1991
6. Zhang XG, Gu ZJ, Lu ZY, Yasukawa K, Yancopoulus GD, Turner K, Shoyab M, Taga T, Kishimoto T, Bataille R, Klein B: Ciliary neurotrophic factor, interleukin 11, leukemia inhibitory factor and oncostatin M are growth factors for human MM cell lines using the interleukin 6 signal transducer gp 130. J Exp Med 179:1337, 1994
7. Brenning G: The in vitro effect of leucocyte-α interferon on human myeloma cells in a semisolid agar culture system. Scand J Hematol 35:178, 1985
8. Jourdan M, Zhang XG, Portier M, Boiron JM, Bataille R, Klein B: IFN-alfa induced autocrine production of IL-6 in MM cell lines. J Immunol 147:4402, 1991
9. Brenning G, Jernberg H, Gidlund M, Sjöberg O, Nilsson K: The effect of alpha- and gamma-interferon on proliferation and production of IgE and β2-microglobulin in the human myeloma cell line U-266 and in an alpha-interferon resistant U-266 subline. Scand J Hematol 36:280, 1986
10. Jernberg-Wiklund H, Pettersson M, Nilsson K: Recombinant interferon-γ inhibits the growth of IL-6 dependent human multiple myeloma cell lines in vitro. Eur J Haematol 46:231, 1991
11. Anderson KC, Jones RM, Morimoto C, Leavitt P, Barut BA: Response patterns of purified multiple myeloma cells to hematopoietic growth factors. Blood 73:1915, 1989
12. Carter A, Merchav S, Silvian-Draxler I, Tatarsky I: The role of interleukin-1 and tumor necrosis-α4 in human multiple myeloma. Br J Haematol 74:424, 1990
13. Zhang XG, Bataille R, Jourdan M, Saeland S, Banchereau J, Mannoni P, Klein B: Granulocyte-macrophage colony stimulating factor synergizes with interleukin-6 in supporting the proliferation of human multiple myeloma cells. Blood 76:2599, 1990
14. Lu ZY, Zhang XG, Rodriguez C, Wijdenes J, Gu ZJ, Morel-Fournier B, Harousseau JL, Bataille R, Rossi JF, Klein B: Interleukin-10 is a proliferation factor but not a differentiation factor for human multiple myeloma cell lines. Blood 85:2521, 1995
15. Kobayashi M, Tanaka J, Imamura M, Maeda S, Iwasaki H, Tanaka M, Tsudu Y, Sakurada K, Miyazaki T: Upregulation of IL-6 receptors by IL-3 on a plasma cell leukemia cell line which proliferates dependently on both IL-3 and IL-6. Br J Haematol 83:535, 1993
16. Baserga R: The insulin-like growth factor I receptor: A key to tumor growth? Cancer Res 55:249, 1995
17. Harrington EA, Bennet MR, Fanidi A, Evan GI: c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 13:3286, 1994
18. Sell C, Baserga R, Rubin R: Insulin-like growth factor 1 (IGF-1) and the IGF-1 receptor prevent etoposide-induced apoptosis. Cancer Res 55:303, 1995
19. Aman P, Lundin G, Hall K, Klein G: Insulin receptors on human lymphoid lines of B-cell origin. Cell Immunol 65:307, 1981
20. Stuart CA, Meehan RT, Neale LS, Cintron NM, Furlanetto RW: Insulin-like growth factor I binds selectively to human peripheral blood monocytes and B-lymphocytes. J Clin Endocrinol Metab 72:1117, 1991
21. Baier TG, Jenne EW, Blum W, Schonberg D, Hartmann KKP: Influence of antibodies against IGF-I, insulin or their receptors on proliferation of human acute lymphoblastic leukemia cell lines. Leuk Res 16:807, 1992
22. Clark R, Strasser J, McCabe S, Robbins K, Jardieu P: Insulin-like growth factor-I stimulation of lymphopoiesis. J Clin Invest 92:540, 1993
23. Jardieu P, Clark R, Mortensen D, Dorshkind K: In vivo administration of insulin-like growth factor-I stimulates primary B lymphopoiesis and enhances lymphocyte recovery after bone marrow transplantation. J Immunol 152:4320, 1994
24. Landreth KS, Narayanan R, Dorshkind K: Insulin-like growth factor-1 regulates pro-B cell differentiation. Blood 80:1207, 1992
25. Gibson LF, Piktel D, Landreth KS: Insulin-like growth factor-1 potentiates expansion of interleukin-7 dependent pro-B cells. Blood 82:3005, 1993
26. Freund GG, Kulas DT, Mooney RA: Insulin and IGF-I increase mitogenesis and glucose metabolism in the multiple MM cell line, RPMI 8226. J Immunol 151:1811, 1993
27. Freund GG, Kulas DT, Way BA, Mooney RA: Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple MM cell lines as compared to B-lymphoblastoid cell lines. Cancer Res 54:3179, 1994
28. Kimata H, Yoshida A: Effect of growth hormone and insulin-like growth factor-1 on immunoglobulin production by and growth of human B cells. J Clin Endocrinol Metab 78:635, 1994
29. Kimata H, Yoshida A: Differential effect of growth hormone and insulin-like growth factor-1, insulin-like growth factor-2, and insulin on Ig production and growth in human plasma cells. Blood 83:1569, 1994
30. Pegoraro L, Malavasi F, Bellone G, Massaia M, Boccadoro M, Saglio G, Guerrasio A, Benetton G, Lombardi L, Coda R, Avanzi GC: The human myeloma cell line LP-1: A versatile model in which to study early plasma cell differentiation and c-myc activation. Blood 73:1020, 1989
31. Hamilton MS, Ball J, Bromidge E, Lowe J, Franklin IM: Characterization of a new IgGλ myeloma plasma cell line (EJM): A further tool in the investigation of the biology of multiple myeloma. Br J Haematol 75:378, 1990
32. Karpas A, Fischer P, Swirsky D: Human plasmacytoma with an unusual karyotype growing in vitro and producing light-chain immunoglobulin. Lancet 1:931, 1982
33. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294, 1979
34. Kawasaki ES: Amplification of RNA, in Innis MA, Gelfand DH, Sninsky JJ, White TJ (eds): PCR Protocols, a Guide to Methods and Applications. San Diego, CA, Academic, 1990
35. Daughaday WH, Mariz IK, Blethen SL: Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: A comparison of radioimmunoassays of somatomedin in native and acid-ethanol-extracted serum. J Clin Endocrinol Metab 51:781, 1980
36. Mohan S, Bautista CM, Herring SJ, Linkhart TA, Baylink DJ: Development of valid methods to measure insulin-like growth factor-I and II in bone cell conditioned medium. Endocrinology 126:2534, 1990
37. Nilsson K: The control of growth in human multiple myeloma cell lines, in Barlogie B, Dammacco F (eds): Multiple Myeloma and Related Disorders, vol 4. Rome, Italy, Ares-Serano Symposia Publications, 1994, 83
38. Jernberg H, Zech L, Nilsson K: Cytogenetic studies on human myeloma cell lines. Int J Cancer 40:811, 1987
39. Dewald GW, Kyle RA, Hicks GA, Greipp P: The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia and amyloidosis. Blood 66:380, 1985
40. Goldring MB, Goldring SR: Cytokines and cell growth control. Crit Rev Eukaryotic Gene Expr 1:301, 1991
41. Baserga R, Rubin R: Cell cycle and growth control. Crit Rev Euk Gene Exp 3:47, 1993
42. Guo Y-S, Beauchamp RD, Jin G-F, Townsend CM, Thompson JC: Insulinlike growth factor-binding protein modulates the growth response to insulin-like growth factor 1 by human gastric cancer cells. Gastroenterology 104:1595, 1993
43. Arteaga CL, Osborne CK: Growth inhibition of human breast cancer cells in vitro with an antibody against the type 1 somatomedin receptor. Cancer Res 49:6237, 1989
44. Kalebic T, Tsokos M, Helman LJ: In vivo treatment with antibody against the IGF-1 receptor suppresses growth of human rhabdomyosarcoma and downregulates p34/cdc 2. Cancer Res 54:5531, 1994
45. Jernberg-Wiklund H, Pettersson M, Carlsson M, Nilsson K: Increase in interleukin-6 (1L-6) and IL-6 receptor expression in a human multiple myeloma cell line, U-266, during long-term in vitro culture and the development of a possible autocrine IL-6 loop. Leukemia 6:310, 1992
46. Middleton J, Arnott N, Walsh S, Beresford J: Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type IIGF receptor. Bone 16:287, 1995
47. Potter M: Perspectives on the origins of multiple myeloma and plasmacytomas in mice. Hematol Oncol Clin North Am 6:211, 1992
48. Jernberg-Wiklund H, Pettersson M, Larsson L-G, Anton R, Nilsson K: Expression of myc family genes in established human multiple myeloma cell lines: L-myc but not c-myc gene expression in the U-266 myeloma cell line. Int J Cancer 51:116, 1992
49. Greil R, Fasching B, Loidl P, Huber H: Expression of the c-myc oncogene in multiple myeloma and chronic lymphocytic leukemia: An in situ analysis. Blood 78:180, 1991
50. Selvanayagam P, Blick M, Narni F, van Tuinen P, Ledbetter DH, Alexanian R, Saunders GF, Barlogie B: Alteration and abnormal expression of the c-myc oncogene in human multiple myeloma. Blood 71:30, 1988
51. Askew D, Ashmun R, Simmons B, Cleveland J: Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppress cell cycle arrest and accelerates apoptosis. Oncogene 6:1915, 1991
52. Pettersson M, Jernberg-Wiklund H, Larsson L-G, Sundström C, Givol I, Tsujimoto J, Nilsson K: Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasmacells. Blood 79:495, 1992
53. Hamilton MS, Barker HF, Ball J, Drew M, Abbot SD, Franklin IM: Normal and neoplastic human plasma cells express bcl-2 antigen. Leukemia 5:768, 1991
54. L. Cancer Res 55:2262, 1995