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Volumn 122, Issue 9, 1996, Pages 554-558

Phase II study of 5-fluorouracil leucovorin and azidothymidine in patients with metastatic colorectal cancer

Author keywords

AZT; Colon cancer; Fluorouracil; Leucovorin

Indexed keywords

FLUOROURACIL; FOLINIC ACID; ZIDOVUDINE;

EID: 9444289362     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01213552     Document Type: Article
Times cited : (6)

References (37)
  • 1
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • Advanced Colorectal Cancer Meta-analysis Project (1992) Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J Clin Oncol 10:896-903
    • (1992) J Clin Oncol , vol.10 , pp. 896-903
  • 2
    • 0028219974 scopus 로고
    • Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer
    • Advanced Colorectal Cancer Meta-analysis Project (1994) Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. J Clin Oncol 12:960-969
    • (1994) J Clin Oncol , vol.12 , pp. 960-969
  • 3
    • 0021200144 scopus 로고
    • Enzymes of the de novo and salvage pathways for pyrimidine biosynthesis in normal colon, colon carcinoma, and xenografts
    • Ahmed NK (1984) Enzymes of the de novo and salvage pathways for pyrimidine biosynthesis in normal colon, colon carcinoma, and xenografts. Cancer 54:1370-1373
    • (1984) Cancer , vol.54 , pp. 1370-1373
    • Ahmed, N.K.1
  • 4
    • 0024564697 scopus 로고
    • Overview of clinical trials using 5-fluorouracil and leucovorin for the treatment of colorectal cancer
    • Arbuck SG (1989) Overview of clinical trials using 5-fluorouracil and leucovorin for the treatment of colorectal cancer. Cancer 63:1036-1044
    • (1989) Cancer , vol.63 , pp. 1036-1044
    • Arbuck, S.G.1
  • 7
    • 0025284426 scopus 로고
    • 5-Fluorouracil enhances azidothymidine cytoloxicity: In vitro, in vivo and biochemical studies
    • Brunetti I, Falcone A, Calabresi P, Goulette KA, Darnowski JW (1990) 5-Fluorouracil enhances azidothymidine cytoloxicity: in vitro, in vivo and biochemical studies. Cancer Res 50:4028-2031
    • (1990) Cancer Res , vol.50 , pp. 4028-2031
    • Brunetti, I.1    Falcone, A.2    Calabresi, P.3    Goulette, K.A.4    Darnowski, J.W.5
  • 9
    • 0026786397 scopus 로고
    • Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA
    • Copeland WC, Chen MS, Wang TS (1992) Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. J Biol Chem 267:21459-21464
    • (1992) J Biol Chem , vol.267 , pp. 21459-21464
    • Copeland, W.C.1    Chen, M.S.2    Wang, T.S.3
  • 10
    • 0011859610 scopus 로고
    • Fluorouracil increases azidothymidine cytotoxicity by altering dTTP pools
    • Darnowski JW, Goulette FA (1992) Fluorouracil increases azidothymidine cytotoxicity by altering dTTP pools. Proc Am Assoc Cancer Res 33:2511
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 2511
    • Darnowski, J.W.1    Goulette, F.A.2
  • 11
    • 0011194375 scopus 로고
    • Synergistic cytoloxicity with α-Interferon and azidothymidine in HCT-8 cells reflects increased azidothymidine incorporation in DNA
    • Darnowski JW Goulette FA (1994) Synergistic cytoloxicity with α-Interferon and azidothymidine in HCT-8 cells reflects increased azidothymidine incorporation in DNA (abstract). Proc Am Assoc Cancer Res 35:1990
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 1990
    • Darnowski, J.W.1    Goulette, F.A.2
  • 12
    • 0142039958 scopus 로고
    • Resistance to azidothymidine cytotoxicity in the human colon tumor cell line HCT15 is associated with enhanced removal of AZT from cellular DNA
    • Darnowski JW, Renaud CA, Chu M, Goulette F, Tosi P, Calabresi P (1991) Resistance to azidothymidine cytotoxicity in the human colon tumor cell line HCT15 is associated with enhanced removal of AZT from cellular DNA (abstract). Proc Am Assoc Cancer Res 32:2124
    • (1991) Proc Am Assoc Cancer Res , vol.32 , pp. 2124
    • Darnowski, J.W.1    Renaud, C.A.2    Chu, M.3    Goulette, F.4    Tosi, P.5    Calabresi, P.6
  • 13
    • 0343262546 scopus 로고
    • Alpha-interferon induced inhibition of DNA repair increases the cytotoxicity of azidothymidine in HCT-8 cells
    • Darnowski JW, Hankinson G, Goulette FA (1995) Alpha-interferon induced inhibition of DNA repair increases the cytotoxicity of azidothymidine in HCT-8 cells (abstract). Proc Am Assoc Cancer Res 36:1773
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 1773
    • Darnowski, J.W.1    Hankinson, G.2    Goulette, F.A.3
  • 14
    • 0027256829 scopus 로고
    • Intralesional interferon-α and zidovudine in epidemic Kaposis sarcoma
    • Dupuy J, Price M, Lynch G, Brucc S, Schwurtz M (1993) Intralesional interferon-α and zidovudine in epidemic Kaposis sarcoma. J Am Acad Dermatol 28:966-972
    • (1993) J Am Acad Dermatol , vol.28 , pp. 966-972
    • Dupuy, J.1    Price, M.2    Lynch, G.3    Bruce, S.4    Schwurtz, M.5
  • 15
    • 0023718558 scopus 로고
    • Interferon effects upon the adeno-carcinoma 38 and HL-60 cell lines. Antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites
    • Elias L and Crissman HA (1988) Interferon effects upon the adeno-carcinoma 38 and HL-60 cell lines. Antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites. Cancer Res 48:4868-4873
    • (1988) Cancer Res , vol.48 , pp. 4868-4873
    • Elias, L.1    Crissman, H.A.2
  • 20
    • 0027531536 scopus 로고
    • Recentn advances in the treatment of advanced colorectal cancer
    • Kemeny N, Lokich JJ, Andersen N, Ahlgren JD (1993) Recentn advances in the treatment of advanced colorectal cancer. Cancer 71:9-18
    • (1993) Cancer , vol.71 , pp. 9-18
    • Kemeny, N.1    Lokich, J.J.2    Andersen, N.3    Ahlgren, J.D.4
  • 21
    • 0025341328 scopus 로고
    • Interferon-α with zidovudine: Safety, tolerance, and clinical and virologic effects in patients with Kaposi sarcoma associated with the acquired immunodeficiency syndrome (AIDS)
    • Krown SE. Gold JWM, Niedzwiecki D, Bundow D, Flomenberg N, Gansbacher B, Brew BJ (1990) Interferon-α with zidovudine: safety, tolerance, and clinical and virologic effects in patients with Kaposi sarcoma associated with the acquired immunodeficiency syndrome (AIDS). Ann Int Med 112:812-821
    • (1990) Ann Int Med , vol.112 , pp. 812-821
    • Krown, S.E.1    Gold, J.W.M.2    Niedzwiecki, D.3    Bundow, D.4    Flomenberg, N.5    Gansbacher, B.6    Brew, B.J.7
  • 22
    • 0026688838 scopus 로고
    • Interferon-α, zidovudine, and granulocyte-macrophage colony-stimulating factor: A phase I AIDS clinical trials group study in patients with Kaposi's sarcoma associated with AIDS
    • Krown SE, Paredes J, Bundow D, Polsky B, Gold JWM, Flomenberg N (1992) Interferon-α, zidovudine, and granulocyte-macrophage colony-stimulating factor: a phase I AIDS clinical trials group study in patients with Kaposi's sarcoma associated with AIDS. J Clin Oncol 10:1344-1351
    • (1992) J Clin Oncol , vol.10 , pp. 1344-1351
    • Krown, S.E.1    Paredes, J.2    Bundow, D.3    Polsky, B.4    Gold, J.W.M.5    Flomenberg, N.6
  • 23
    • 0024581065 scopus 로고
    • Leucovorin enhancement of the effects of fluoropynmidines on thymidylate synthase
    • Moran RG (1989) Leucovorin enhancement of the effects of fluoropynmidines on thymidylate synthase. Cancer 63:1008-1012
    • (1989) Cancer , vol.63 , pp. 1008-1012
    • Moran, R.G.1
  • 25
    • 0027483228 scopus 로고
    • Low-dose interferon alpha combined with zidovudine in patients with AIDS associated Kaposi's sarcoma
    • Podzamczer D, Bolao F, Clotet B, Garcia P, Casanova A, Pagerols X, Gudiol F (1993) Low-dose interferon alpha combined with zidovudine in patients with AIDS associated Kaposi's sarcoma. J Intern Med 233:247-253
    • (1993) J Intern Med , vol.233 , pp. 247-253
    • Podzamczer, D.1    Bolao, F.2    Clotet, B.3    Garcia, P.4    Casanova, A.5    Pagerols, X.6    Gudiol, F.7
  • 29
    • 0026537317 scopus 로고
    • Fluorouracil plus interferon + folinic acid in regional and systemic therapy in colorectal cancer
    • Preiss J (1992) Fluorouracil plus interferon + folinic acid in regional and systemic therapy in colorectal cancer. Semin Oncol 19 [Suppl 3]:220-224
    • (1992) Semin Oncol , vol.19 , Issue.3 SUPPL. , pp. 220-224
    • Preiss, J.1
  • 30
    • 0027427801 scopus 로고
    • Combination studies with 3′-azido-3′-deoxythymidine (AZT) plus ICI D1694. Cytotoxic and biochemical effects
    • Pressacco J, Erlichman C (1993) Combination studies with 3′-azido-3′-deoxythymidine (AZT) plus ICI D1694. Cytotoxic and biochemical effects. Biochem Pharmacol 46:1989-1997
    • (1993) Biochem Pharmacol , vol.46 , pp. 1989-1997
    • Pressacco, J.1    Erlichman, C.2
  • 31
    • 0029055178 scopus 로고
    • Treatment of advanced colorectal cancer with 5-fluorouracil and interferon-α: An overview of clinical trials
    • Raderer M, Scheithauer W (1995) Treatment of advanced colorectal cancer with 5-fluorouracil and interferon-α: an overview of clinical trials. Eur J Cancer 31A: 1002-1008
    • (1995) Eur J Cancer , vol.31 A , pp. 1002-1008
    • Raderer, M.1    Scheithauer, W.2
  • 33
    • 0027140414 scopus 로고
    • Synergistic cytotoxicity of AZT plus alpha and gamma Interferon in chronic myeloid leukemia cell line K562
    • Tosi P, Visani G, Ottaviani E, Gamberi B, Cenacehi A, Tura S (1993) Synergistic cytotoxicity of AZT plus alpha and gamma Interferon in chronic myeloid leukemia cell line K562. Eur J Haematol 51:209 -213
    • (1993) Eur J Haematol , vol.51 , pp. 209-213
    • Tosi, P.1    Visani, G.2    Ottaviani, E.3    Gamberi, B.4    Cenacehi, A.5    Tura, S.6
  • 34
    • 0025052138 scopus 로고
    • Interaction of Fluorouracil and Interferon in human colon cancer cell lines. Cytotoxic and cytokinetic effects
    • Wadler S, Wersto R, Weinberg V, Thompson D, Scwartz EL (1990) Interaction of Fluorouracil and Interferon in human colon cancer cell lines. Cytotoxic and cytokinetic effects. Cancer Res 50:5735 -5739
    • (1990) Cancer Res , vol.50 , pp. 5735-5739
    • Wadler, S.1    Wersto, R.2    Weinberg, V.3    Thompson, D.4    Scwartz, E.L.5
  • 35
    • 0025147156 scopus 로고
    • Azido-thymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepaloma and human colon cancer cells
    • Weber G, Ichikawa S, Nagai M, Natsumeda Y (1990) Azido-thymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepaloma and human colon cancer cells. Cancer Commun 2:129 -133
    • (1990) Cancer Commun , vol.2 , pp. 129-133
    • Weber, G.1    Ichikawa, S.2    Nagai, M.3    Natsumeda, Y.4
  • 36
    • 0027380603 scopus 로고
    • Zidovudine. An update of its pliarmacodynamic and pharmacokinetic properties, and therapeutic efficacy
    • Wilde MI, Lantry HD (1993) Zidovudine. An update of its pliarmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 46:515 -578
    • (1993) Drugs , vol.46 , pp. 515-578
    • Wilde, M.I.1    Lantry, H.D.2
  • 37
    • 0026989338 scopus 로고
    • Azidothymidine and dipyrimidole as biochemical response modifiers: Synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells
    • Zhen YS, Taniki T, Weber G (1992) Azidothymidine and dipyrimidole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells. Oncol Res 4:73 -78
    • (1992) Oncol Res , vol.4 , pp. 73-78
    • Zhen, Y.S.1    Taniki, T.2    Weber, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.