Echocardiographic and electrocardiographic prognostic factors of heart failure in young patients with β-thalassemia major: A 10-year (1995-2004) follow-up

International Journal of Hematology

Volumn 80, Issue 4, 2004, Pages 336-340

  Chrysohoou, Christina ^a,d   Panagiotakos, Demosthenes B ^a   Barbetseas, Yannis ^a   Brilli, Stella ^a   Lambrou, Spyros ^b   Karagiorga, Markissia ^c   Ladis, Vassilis A ^c   Pitsavos, Christos ^a   Stefanadis, Christodoulos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b Iatriko Medical Center   (Greece)

^c Pediatric Hospital Saint Sophia   (Greece)

^d NONE   (Greece)

Author keywords

Thalassemia; Heart failure; Prognostic factors

Indexed keywords

DEFEROXAMINE; FERRITIN; HEMOGLOBIN;

ADULT; AGE; AORTA ROOT; BODY MASS; CLINICAL FEATURE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; ERYTHROCYTE TRANSFUSION; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; GREECE; HEART ARRHYTHMIA; HEART FAILURE; HEART LEFT ATRIUM; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE SIZE; HEART RATE; HUMAN; IRON CHELATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; QRS COMPLEX; REVIEW; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; T WAVE; THALASSEMIA MAJOR;

ADULT; BETA-THALASSEMIA; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE, CONGESTIVE; HUMANS; MALE; PROGNOSIS; RISK FACTORS;

EID: 9444280947     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1532/IJH97.E0407     Document Type: Review

References (18)

1. Zurlo MG, Stefano P, Borgna-Pignatti C, et al. Survival and cases of death in thalassaemia major. Lancet. 1989;2:27-30.
2. Kremastinos DT, Flevari P, Spyropoulou M, Vrettou H, Tsiapras D, Stavropoulos-Giokas CG. Association of heart failure in homozygous β-thalassemia with the major histocompatibility complex. Circulation. 1999;100:2074-2078.
3. Kremastinos D, Tiniakos G, Thedorakis GN, Katritsis DG, Toutouzas PK. Myocarditis in β-thalassemia major: a cause of heart failure. Circulation. 1995;91:66-71.
4. Koren A, Gartv I, Antonelli D, et al. Right ventricular cardiac dysfunction in beta-thalassemia major. Am J Dis Child. 1987;141:93-96.
5. New York Heart Association Criteria Committee. Diseases of the Heart and Blood Vessels. Nomenclature and Criteria for Diagnosis. 6th ed. Boston, Mass: Little, Brown and Company; 1964.
6. Remme WJ, Swedberg K, and the Task Force for the Diagnosis and Treatment of Chronic Heart Failure, European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J. 2001;22:1527-1560.
7. Kremastinos DT. Heart failure in β-thalassemia. Congest Heart Fail. 2001;7:312-314.
8. Crisaru D, Rachmilewitz EA, Mosseri M, et al. Cardiopulmonary assessment in beta-thalassemia major. Chest. 1990;98:1138-1142.
9. Kremastinos DT, Toutouzas PK, Vyssoulis GP, Venetis CA, Avgoustakis DG. Iron overload and left ventricular performance in beta thalassemia. Acta Cardiol. 1984;39:29-40.
10. Kremastinos DT, Toutouzas PK, Vyssoulis GP, Venetis CA, Vretou HP, Avgoustakis DG. Global and segmental left ventricular function in beta-thalassemia. Cardiology. 1985;72:129-139.
11. Kremastinos D, Tsetsos G, Tsiapras D, Karavolias G, Ladis V, Kattamis C. Heart failure in beta thalassemia: A 5-year follow-up study. Am J Med. 2001;111:349-354.
12. Mavrogeni SI, Maris T, Gouliamos A, Vlahos L, Kremastinos DT. Myocardial iron deposition in beta-thalassemia patients studied with magnetic resonance imaging. Int J Card Imaging. 1998;14:117-122.
13. Jacobs A, Miller F, Worwood M, Beamish MR, Wardrop CA. Ferritin in the serum of normal subjects with iron deficiency and iron overload. Br Med J. 1972;4:206-211.
14. Kremastinos DT, Tsiapras D, Tsetsos G, Rentoukas EI, Vretou HP, Toutouzas PK. Left ventricular diastolic Doppler characteristics in beta-thalassemia major. Circulation. 1993;88:1127-1135.
15. Klingenheben T, Zabel M, D'Agostino RB, Cohen RJ, Hohnloser ST. Predictive value of T-wave alternans for arrhythmic events in patients with congestive heart failure. Lancet 2000;356:651-652.
16. Vaccari M, Crepaz R, Fortini M, et al. Left ventricular remodeling, systolic function, and diastolic function in young adults with β-thalassemia intermedia: a Doppler echocardiography study. Chest. 2002;121:506-512.
17. Veglio F, Melchio R, Rabblia F, et al. Blood pressure and heart rate in young thalassemia major patients. Am J Hypertens. 1998;11:539-547.
18. Cleland JG, Swedberg K, Follath F, et al, and the Study Group on Diagnosis of the Working Group on Heart Failure of the European Society of Cardiology. The EuroHeart Failure survey program: a survey on the quality of care among patients with heart failure in Europe, part 1: patient characteristics and diagnosis. Eur Heart J. 2003;24:442-463.