Posttransplant lymphoproliferative disease in pediatric liver transplantation: Interplay between primary Epstein-Barr virus infection and immunosuppression

Transplantation

Volumn 62, Issue 3, 1996, Pages 370-375

  Newell, Kenneth A ^a   Alonso, Estella M ^a   Whitington, Peter F ^a   Bruce, Davtd S ^a   Millis, J Michael ^a   Piper, James B ^a   Woodle, E Steve ^a   Kelly, Susan M ^a   Koeppen, Hartmut ^a   Hart, John ^a   Rubin, Charles M ^a   Thistlethwaite Jr , J Richard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OKT 3; TACROLIMUS;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GRAFT REJECTION; HUMAN; LIVER TRANSPLANTATION; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD;

EID: 9444259791     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199608150-00012     Document Type: Article

References (29)

1. Penn I. De novo malignancy in pediatric organ transplant recipients. J Pediatr Surg 1994; 29(2): 221.
2. Kieff E, Liebowitz D. Epstein-Barr virus and its replication. In: Fields BN, Knipe DM, Chanock RM, eds. Fields virology. New York: Raven, 1990: 1889.
3. Niederman JC, Evans AS, Subrahmanyan L, McCollum RW. Prevalence, incidence and persistence of EB virus antibody in young adults. N Engl J Med 1970; 282: 361.
4. Swinnen LJ, Costanzo-Nordin MK, Fisher SG, et al. Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac-transplant recipients. N Engl J Med 1990; 323: 1723.
5. Malatack J, Gartner J, Urbach A, Zitelli B. Orthotopic liver transplantation, Epstein Barr virus, cyclosporine and lymphoproliferative disease: a growing concern. J Pediatr 1991; 11: 667.
6. Fischer A, Blanche S, Le Bidois J, et al. Anti B cell monoclonal antibodies in the treatment of severe B cell lymphoproliferative syndrome following bone marrow and organ transplantation. N Engl J Med 1991; 324: 1451.
7. Williams ML, Loughran TP, Kidd PG, Starkebaum GA. Polyclonal proliferation of activated suppressor/cytotoxic T cells with transient depression of natural killer cell function in acute infectious mononucleosis. Clin Exp Immunol 1989; 77(1): 71.
8. Miyawaki T, Kasahara Y, Kanegane H, et al. Expression of CD45RO (UCHL1) by CD4+ and CD8+ T cells as a sign of in vivo activation in infectious mononucleosis. Clin Exp Immunol 1991; 83(3): 447.
9. Nalesnik M, Locker J, Jaffe R, et al. Experience with posttransplant lymphoproliferative disorders in solid organ transplant patients. Clin Transplant 1992; 6(special issue): 249.
10. Broelsch CE, Emond JC, Whitington PF, Thistlethwaite JR, Baker AL, Lichtor JL. Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants. Ann Surg 1990; 212(3): 368.
11. Whitington PF, Alonso EM. Special issues related to pediatric immunosuppression. In: Wiesner RH, Lake JR, eds. Liver transplantation. New York: John Wiley and Sons, 1995.
12. Whitington PF, Emond JC, Whitington SH, Broelsch CE, Baker AL. Small-bowel length and the dose of cyclosporine in children after liver transplantation. N Engl J Med 1990; 322: 733.
13. Hart J, Lewin KJ. Liver allograft pathology. In: Ferrell LD, eds. Pathology: state of the art reviews. Philadelphia: Hanley & Belfus, 1994: 207.
14. Aran PP, Bostwick DA, Bissell M, et al. The clinical utility of liver biopsy in the diagnosis of post liver transplantation graft rejection. Clin Transplant 1994; 7: 475.
15. Sumaya CV, Jenson HB. Epstein-Barr virus. In: Rose N, DeMacario E, Fahey J, Friedman H, Penn G, eds. Manual of clinical immunology. Washington, DC: ASM, 1992: 568.
16. Sokal EM, Caragiozoglou T, Lamy M, Reding R, Otte JB. Epstein-Barr virus serology and Epstein-Barr virus-associated lymphoproliferative disorders in pediatric liver transplant recipients. Transplantation 1993; 56: 1394.
17. Cox KL, Lawrence-Miyasaki LS, Garcia-Kennedy R, et al. An increased incidence of Epstein-Barr virus infection and lymphproliferative disorder in young children on FK506 after liver transplantation. Transplantation 1995; 59: 524.
18. Renard TH, Andrews WS, Foster ME. Relationship between OKT3 administration, EBV seroconversion, and the lymphoproliferative syndrome in pediatric liver transplant recipients. Transplant Proc 1991; 23(1): 1473.
19. Morgan G, Superina RA. Lymphoproliferative disease after pediatric liver transplantation. J Pediatr Surg 1994; 29(9): 1192.
20. Ho M, Jaffe R, Miller G, et al. The frequency of Epstein-Barr virus infection and associated lymphoproliferative syndrome after transplantation and its manifestations in children. Transplantation 1988; 45(4): 719.
21. Ho M, Miller G, Atchison RW, et al. Epstein-Barr virus infections and DNA hybridization studies in posttransplantation lymphoma and lymphoproliferative lesions: the role of primary infection. J Infect Dis 1985; 152(5): 876.
22. Starzl TE, Nalesnik M, Porter KA, et al. Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet 1984; 1(8377): 583.
23. Reyes J, Tzakis A, Green M, et al. Post-transplant lymphoproliferative disorders occurring under primary FK506 immunosuppression. Transplant Proc 1991; 23: 3044.
24. Reding R, Wallemacq PE, Lamy ME, et al. Conversion from cyclosporine to FK506 for salvage of immunocompromised pediatric liver allografts. Transplantation 1994; 57(1): 93.
25. Egeler RM, Neglia JP, Puccetti DM, Brennan CA, Nesbit ME. Association of Langerhans cell histiocytosis with malignant neoplasms. Cancer 1993; 71(3): 865.
26. Cohen JI. Epstein-Barr virus lymphoproliferative disease associated with acquired immunodeficiency. Medicine 1991; 70(2): 137.
27. Taguchi Y, Purtilo DT, Okano M. The effect of intravenous immunoglobulin and interferon-a on Epstein-Barr virus-induced lymphoproliferative disorder in a liver transplant recipient. Transplantation 1994; 57(12): 1813.
28. Filipovich AH, Mathur A, Kamat D, Kersey JH, Shapiro RS. Lymphoproliferative disorders and other tumors complicating immunodeficiencies. Immunodeficiency 1994; 5(2): 91.
29. Randhawa PS, Jaffe R, Demetris AJ, et al. Expression of Epstein-Barr virus-encoded small RNA (by the EBER-1 gene) in liver specimens from transplant recipients with post-transplantation lymphoproliferative disease. N Engl J Med 1992; 327(24): 1710.