Dioxinlike properties of a trichloroethylene combustion-generated aerosol

Environmental Health Perspectives

Volumn 104, Issue 7, 1996, Pages 734-743

  Villalobos, S Alex ^a   Anderson, Michael J ^a   Denison, Michael S ^a   Hinton, David E ^a   Tullis, Katherine ^a   Kennedy, Ian M ^b   Jones, A Daniel ^a   Chang, Daniel P Y ^b   Yang, GoSu ^b   Kelly, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California   (United States)

Author keywords

Ah receptor; Antiestrogen; Complex mixture; Dioxin like toxicity; Dioxin response element binding; Embryo cardiovascular toxicity; Incomplete combustion by products; Liver; Trichloroethylene; Vitellogenin

Indexed keywords

ANTIESTROGEN; CYTOCHROME P450; DIOXIN; ETHOXYRESORUFIN DEETHYLASE; LACTATE DEHYDROGENASE; METHYL CHLORIDE; TRICHLOROETHYLENE; VITELLOGENIN;

AEROSOL; ANIMAL CELL; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; EMBRYO; EMBRYOTOXICITY; FEMALE; LIVER CELL CULTURE; MALE; NONHUMAN; PRIORITY JOURNAL; TOXICOLOGY;

ANIMALIA; LATIPES; MYKISS; ONCORHYNCHUS MYKISS; ORYZIAS LATIPES; SALMONIDAE;

EID: 9444255076     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.96104734     Document Type: Article

References (67)

1. 10 cyclopenta-fused polycyclic aromatic hydrocarbons associated with fossil fuels combustion. Environ Health Perspect 101:146-153 (1993).
2. Seeker WR. Waste combustion. Twenty-third symposium (international) on combustion. Pittsburgh PA:The Combustion Institute, 1990;867-886.
3. Wendt JOL. Combustion science for incineration technology. Twenty-fifth symposium (international) on combustion. Pittsburgh PA:The Combustion Institute, 1994;277-289.
4. Linak WP, Kilgroe JD, McSorley JA, Wendt JOL, Dunn JE. On the occurrence of transient puffs in a rotary kiln incinerator simulator I. Prototype solid plastic wastes. J Air Pollut Control Assoc 37:54-65 (1987).
5. Linak WP, McSorley JA, Wendt JOL, Dunn JE. On the occurrence of transient puffs in a rotary kiln incinerator simulator II. Contained liquid on sorbent. J Air Pollut Control Assoc 37:934-942 (1987).
6. Wendt JOL, Linak WP. Mechanisms governing transients from the batch incineration of liquid wastes from rotary kilns. Comb Sci Technol 61:169-185 (1988).
7. Safe S. Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. Annu Rev Pharm Toxicol 26:371-399 (1986).
8. Oppelt T. Incineration of hazardous waste: a critical review. J Air Pollut Control Assoc 37:558 (1987).
9. Revelle R. The Ocean. Sci Am 22:56-65 (1968).
10. Webster T, Commoner B. Overview: the dioxin debate. In: Dioxins and health (Schecter A, ed). New York:Plenum Press, 1994;1-50.
11. Safe S. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21(1):51-88 (1990).
12. Giesy JP, Ludwig JP, Tillitt DE. Dioxins, dibenzofurans, PCBs and wildlife. In: Dioxins and health (Schecter A, ed). New York:Plenum Press 1994;249-294.
13. Poland A, Knutson JC. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharm Toxicol 22:517-554 (1982).
14. Blankenship A, Chang DPY, Jones AD, Kelly PB, Kennedy IM, Matsumura F, Pasek R, Yang G. Toxic combustion by-products from the incineration of chlorinated hydrocarbons and plastics. Chemosphere 28(1): 183-196 (1994).
15. Marry GD, Núñez JM, Lauren DJ, Hinton DE. Age-dependent changes in toxicity of N-nitroso compounds to Japanese medaka (Oryzias latipes) embryos. Aquat Toxicol 17:45-62 (1990).
16. Kirchen RV, West WR. The Japanese medaka, its care and development. Burlington, NC:Carolina Biological Co, 1976.
17. Marty GD, Wetzlich S, Núñez JM, Craigmill A, Hinton DE. Fish-based biomonitoring to determine toxic characteristics of complex chemical mixtures: documentation of bioremediation at a pesticide disposal site. Aquat Toxicol 19:329-340 (1991).
18. Wisk JD, Cooper KR. The stage specific toxicity of 2,3,7,8-tetrachloro-dibenzo-p-dioxin in embryos of the Japanese medaka (Oryzias latipes). Environ Toxicol Chem 9:1159-1169 (1990).
19. Harris GE, Metcalfe TL, Metcalfe CD, Huestis SY. Embryotoxicity of extracts from Lake Ontario rainbow trout (Oncorhynchus mykiss) to Japanese medaka (Oryzias latipes). Environ Toxicol Chem 13(9):1393-1403 (1994).
20. Harris GE, Kiparissis Y, Metcalfe CD. Assessment of the toxic potential of PCB congener 81 (3,4,4′,5-tetrachlorobiphenyl) to fish in relation to other non-ortho-substituted PCB congeners. Environ Toxicol Chem 13 (9):1405-1413 (1994).
21. Marty GD, Cech JJ, Hinton DE. Effect of incubation temperature on oxygen consumption and ammonia production by Japanese medaka (Oryzias latipes) eggs and newly hatched larva. Environ Toxicol Chem 9:1397-1403 (1990).
22. Teh SJ, Hinton DE. Detection of enzyme histochemical markers of hepatic preneoplasia in medaka (Oryzias latipes). Aquat Toxicol 24:163-182 (1993).
23. Blair JB, Miller MR, Pack D, Barnes RB, Teh SJ, Hinton DE. Isolated trout liver cells: establishing short term primary cultures exhibiting cell-to-cell interactions. In vitro Cell Dev Biol 26(3):237-249 (1990).
24. Moon TW, Walsh PJ, Mommsen TP. Fish hepatocytes: a model metabolic system. Can J Fish Aquat Sci 42:1772-1782 (1985).
25. Pesonen M, Andersson T. Characterization and induction of xenobiotic metabolizing enzyme activities in a primary culture of rainbow trout hepatocytes. Xenobiotics 21(4):461-471 (1991).
26. Anderson MJ, Miller MR, Hinton DE. In vitro modulation of 17β-estradiol-induced vitellogenin synthesis: effects of cytochrome P4501A1 inducing compounds on rainbow trout (Oncorhynchus mykiss) liver cells. Aquat Toxicol 34:1-24 (1996).
27. Goksoyr A. A semi-quantitative cytochrome P4501A1 ELISA: a simple method for studying the monooxygenase induction response in environmental monitoring and ecotoxocological testing of fish. Sci Total Environ 101:255-262 (1991).
28. Segner H, Blair JB, Wirtz G, Miller MR. Cultured trout liver cells: utilization of substrates and response to hormones. In vitro Cell Dev Biol 30A:306-311 (1994).
29. Burke MD, Thompson S, Elcombe CR, Halpert J, Haaparanta T, Mayer RT. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol 34 (18):3337-3345 (1985).
30. Bergmeyer HU, Bernt E. Lactate dehydrogenase: UV assay with pyruvate and NADH. In: Methods of enzymatic analysis, vol 2 (Bergemeyer HC, ed). New York:Academic Press, 1974;574-579.
31. Bank PA, Yao ES, Phelps CL, Harper PA, Denison MS. Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer. Eur J Pharmacol 228:85-94 (1992).
32. Denison MS, Yao EF. Characterization of the interaction of transformed rat hepatic Ah receptor with a dioxin responsive transcriptional enhancer. Arch Biochem Biophys 284:158-166 (1991).
33. Helferich WG, Denison MS. Photo oxidized products of tryptophan can act as dioxin agonists. Mol Pharmacol 40:674-678 (1991).
34. Bradford MM. A rapid sensitive method for the quantitation of microgram of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254 (1976).
35. Stone R. Dioxins dominate Denver gathering of toxicologists. Science 266:1162-1163 (1994).
36. Walker MK, Peterson RE. Potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners, relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin, for producing early life stage mortality in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol 21:219-238 (1991).
37. Spitsbergen JM, Walker MK, Olson JR, Peterson RE. Pathological alterations in early life stages of lake trout, Salvelinus namaycush, exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin as fertilized eggs. Aquat Toxicol 19:41-72 (1991).
38. Rifkind AB, Hattori Y, Levi R, Hughes MJ, Qulley C, Alonso DR. The chick embryo as a model for PCB and dioxin toxicity: evidence of cardiotoxicity and increased prostaglandin synthesis. In: Biological mechanisms of dioxin action, Banbury report 18 (Poland A, Kimbroug RD, eds). Cold Spring Harbor, NY:Cold Spring Harbor Laboratory 1984;255-265.
39. Schwetz BA, Norris JM, Sparschu GL, Rowe VK, Gehring PJ, Emerson JL, Gerbig CG. Toxicology of chlorinated dibenzo-p-dioxins. Environ Health Perspect 5:87-99 (1973).
40. Stohs SJ, Hassan MQ, Murray WJ. Induction of lipid peroxidation and inhibition of glutathione peroxidase by TCDD. In: Biological mechanisms of dioxin action, Banbury Report 18 (Poland A, Kimbrough RD, eds). Cold Spring Harbor, NY:Cold Spring Harbor Laboratory 1984;241-253.
41. Canga L, Paroli L, Blanck TJJ, Silver RB, Rifkind AB. 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases cardiac myocyte intracellular calcium and progressively impairs ventricular contractile responses to isoproterenol and to calcium in chick embryo hearts. Mol Pharmacol 44:1142-1151. (1993).
42. Spitsbergen JM, Kleeman JM, Peterson RE. 2,3,7,8-Tetrachlorodibenzo-p-dioxin toxicity in yellow perch (Perca flavescens). J Toxicol Environ Health 23:359-383 (1988).
43. Stegeman JJ, Hahn ME, Weisbrod R, Woodin BR, Joy JS, Soheil N, Cohen RA. Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol Pharmacol 47:296-306 (1995).
44. Stegeman JJ, Miller MR, Hinton DE. Cytochrome P450IA1 induction and localization in endothelium of vertebrate (teleost) heart. Mol Pharmacol 36:723-739 (1989).
45. Stegeman JJ, Hahn ME. Biochemistry and molecular biology of monooxygenases: current perspectives on forms, functions, and regulation of cytochrome P450 in aquatic species. In: Aquatic toxicology (Malins DC, Ostrander GK, eds). Boca Raton, FL:CRC Press, Inc., 1994;87-206.
46. Fruetel JA, Sparks SE, Quistad GB, Casida JE. Adducts of dienochlor miticide with glutathione, glutathione S-transferases, and hemoglobins. Chem Res Toxicol 7:487-494 (1994).
47. Wisk JD, Cooper KR. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on benzo(a)pyrene hydroxylase activity in embryos of the Japanese medaka (Oryzias latipes). Arch Toxicol 66:245-249 (1992).
48. Bhattacharayya KK, Brake PB, Eltom SE, Otto SA, Jefcoate CR. Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of the unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-link regulation. J Biol Chem 270 (19):11595-11602 (1995).
49. Miller MR, Hinton DE, Blair JB. Characterization of BNF-inducible cytochrome P-450IA1 in cultures of rainbow trout liver cells. Mar Environ Res 28:105-108 (1989).
50. Miller MR, Saito N, Blair JB, Hinton DE. Acetaminophen toxicity in cultured trout liver cells. 2. Maintenance of cytochrome P4501A1. Exp Mol Pathol 58:127-138 (1993).
51. Pesonen M, Andersson T. Toxic effects of bleached and unbleached paper mill effluents in primary cultures of rainbow trout hepatocytes. Ecotoxicol Environ Saf 24:63-71 (1992).
52. Pesonen M, Goksoyr A, Andersson T. Expression of P4501A1 in a primary culture of rainbow trout hepatocytes exposed to β-naphthoflavone or 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch Biochem Biophys 292(1): 228-233 (1992).
53. Thomas P. Teleost model for studying the effects of chemicals on female reproductive endocrine function. J Exp Zoo(suppl 4): 126-128 (1990).
54. Mommsen TP, Walsh PJ. Vitellogenesis and oocyte assembly. In: Fish physiology (Hoar WS, Randall DJ, eds). New York:Academic Press, 1988;347-406.
55. Safe S, Astroff B, Harris M, Zacharewski T, Dickerson R, Romkes M, Biegel L. Minireview: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antiestrogens: characterization and mechanism of action. Pharmacol Toxicol 69:400-409 (1991).
56. Pajor AM, Stegeman JJ, Thomas P, Woodin BR. Feminization of the hepatic microsomal cytochrome P-450 system in brook trout by estradiol, testosterone, and pituitary factors. J Exp Zoo 253:51-60 (1990).
57. Neben DW, Bausserman LL, Bates RR. Effect of 17-β-estradiol and testosterone on aryl hydrocarbon hydroxylase acivity in mouse tissues in vivo and in cell culture. Int J Cancer 6:470-480 (1970).
58. Gooch JW, Elskus AA, Kloepper-Sams PJ, Hahn ME, Stegeman JJ. Effects of ortho- and non-ortho-substituted polychlorinated biphenyl congeners on the hepatic monooxygenase system in scup (Stenotomus chrysops). Toxicol Appl Pharmacol 98:422-433 (1989).
59. Hahn ME, Lamb TM, Schultz ME, Smolowitz RM, Stegeman JJ. Cytochrome P4501A induction and inhibition by 3,3′,4,4′-tetrachlorobiphenyl in an Ah receptor-containing fish hepatoma cell line (PLHC-1). Aquat Toxicol 26:185-208 (1993).
60. Chaloupka K, Krishnan V, Safe S. Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells: role of the Ah receptor. Carcinogenesis 13(12): 2233-2239 (1992).
61. Safe S. Toxicology, structure-function relationships, and human and environmental health impacts of polychlorinated biphenyls: progress and problems. Environ Health Perspect 100:259-268 (1992).
62. Henry EC, Rucci G, Gasiewicz TA. Characterization of multiple forms of the Ah receptor. Biochem 28:6430-6440 (1989).
63. Whitlock JP. The regulation of cytochrome P-450 gene expression. Annu Rev Pharm Toxicol 26:333-369 (1986).
64. Whitlock JP. Genetic and molecular aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin action. Annu Rev Pharm Toxicol 30:251-277 (1990).
65. Denison MS, Fisher JM, Whitlock JP Jr. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc Natl Acad Sci USA 85:2528-2532 (1988).
66. Denison MS, Fisher JM, Whitlock JP Jr. The DNA recognition site for the dioxin-Ah receptor complex: nucleotide sequence and functional analysis. J Biol Chem 263:17221-17224 (1988).
67. El-Fouly MH, Richter C, Giesy JP, Denison MS. Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Environ Toxicol Chem 13(10):1581-1588 (1994).