Amphotericin B molecular organization as an essential factor to improve activity/toxicity ratio in the treatment of visceral leishmaniasis

Journal of Drug Targeting

Volumn 12, Issue 7, 2004, Pages 453-460

  Sanchez Brunete J A ^a   Dea, M A ^a   Rama, S ^a   Bolas F ^a   Alunda, J M ^b   Torrado Santiago, S ^a   Torrado, J J ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Amphotericin B; Leishmaniasis; Non water soluble multi aggregates; Toxicity

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; CAVITRON 84000; GAMMA CYCLODEXTRIN; MONOMER;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; IN VIVO STUDY; LEISHMANIA INFANTUM; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SYRIAN HAMSTER; TOXICITY TESTING; VISCERAL LEISHMANIASIS;

AMPHOTERICIN B; ANIMALS; ANTIBODY FORMATION; ANTIPROTOZOAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CRICETINAE; IMMUNOGLOBULIN G; KIDNEY DISEASES; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; LIVER; MALE; MESOCRICETUS; SPECTROPHOTOMETRY, ULTRAVIOLET; SPLEEN;

EID: 9444248164     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860400006596     Document Type: Article

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