Recurrent aphthous stomatitis

Dental Clinics of North America

Volumn 49, Issue 1 SPEC.ISS., 2005, Pages 31-47

  Akintoye, Sunday O ^a   Greenberg, Martin S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CLOTRIMAZOLE; COLCHICEINE; CORTICOSTEROID; DAPSONE; ETANERCEPT; METHYLXANTHINE; ORABASE; PENTOXIFYLLINE; PREDNISONE; RECOMBINANT TUMOR NECROSIS FACTOR; STEROID; SULFONE; THALIDOMIDE; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; APHTHOUS STOMATITIS; BIRTH DEFECT; CLINICAL FEATURE; CLINICAL TRIAL; CORRELATION ANALYSIS; CYTOMEGALOVIRUS; DEMOGRAPHY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; DROWSINESS; DRUG SAFETY; ETHNOLOGY; GENETIC DISORDER; HUMAN; MOUTH DISEASE; MOUTH MUCOSA; MOUTH ULCER; NEUTROPENIA; PATHOGENESIS; PERIPHERAL NEUROPATHY; RECURRENT DISEASE; REVIEW; RISK FACTOR; SALIVARY GLAND; SIDE EFFECT; SMOKING; SOCIOECONOMICS; STREPTOCOCCUS; STRESS; SYSTEMIC DISEASE; VARICELLA ZOSTER VIRUS;

EID: 9444241480     PISSN: 00118532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cden.2004.08.001     Document Type: Review

References (94)

1. R.S. Rogers III Recurrent aphthous stomatitis: clinical characteristics and associated systemic disorders Semin Cutan Med Surg 16 4 1997 278 283
2. D.V. Kleinman, P.A. Swango, and L.C. Niessen Epidemiologic studies of oral mucosal conditions-methodologic issues Community Dent Oral Epidemiol 19 3 1991 129 140
3. M.F. Miller, A.A. Garfunkel, C.A. Ram, and Ship II The inheritance of recurrent aphthous stomatitis. Observations on susceptibility Oral Surg Oral Med Oral Pathol 49 5 1980 409 412
4. Ship II Epidemiologic aspects of recurrent aphthous ulcerations Oral Surg Oral Med Oral Pathor 33 3 1972 400 406
5. M.R. Crivelli, S. Aguas, I. Adler, C. Quarracino, and P. Bazerque Influence of socioeconomic status on oral mucosa lesion prevalence in schoolchildren Community Dent Oral Epidemiol 16 1 1988 58 60
6. J.A. Ship, E.M. Chavez, P.A. Doerr, B.S. Henson, and M. Sarmadi Recurrent aphthous stomatitis Quintessence Int 31 2 2000 95 112
7. D. Wray, E.A. Graykowski, and A.L. Notkins Role of mucosal injury in initiating recurrent aphthous stomatitis Br Med J (Clin Res Ed) 283 6306 1981 1569 1570
8. O.J. Stone Aphthous stomatitis (canker sores): a consequence of high oral submucosal viscosity (the role of extracellular matrix and the possible role of lectins) Med Hypotheses 36 4 1991 341 344
9. I. Espinoza, R. Rojas, W. Aranda, and J. Gamonal Prevalence of oral mucosal lesions in elderly people in Santiago, Chile J Oral Pathol Med 32 10 2003 571 575
10. P.A. Atkin, X. Xu, and M.H. Thornhill Minor recurrent aphthous stomatitis and smoking: an epidemiological study measuring plasma cotinine Oral Dis 8 3 2002 173 176
11. T. Axell, and V. Henricsson Association between recurrent aphthous ulcers and tobacco habits Scand J Dent Res 93 3 1985 239 242
12. L. Salonen, T. Axell, and L. Hellden Occurrence of oral mucosal lesions, the influence of tobacco habits and an estimate of treatment time in an adult Swedish population J Oral Pathol Med 19 4 1990 170 176
13. B. Tuzun, R. Wolf, Y. Tuzun, and S. Serdaroglu Recurrent aphthous stomatitis and smoking Int J Dermatol 39 5 2000 358 360
14. B.E. McCartan, P.J. Lamey, and A.M. Wallace Salivary cortisol and anxiety in recurrent aphthous stomatitis J Oral Pathol Med 25 7 1996 357 359
15. M. Maurice, W. Mikhail, M. Aziz, and M. Barsoum Aetiology of recurrent aphthous ulcers (RAU) J Laryngol Otol 101 9 1987 917 920
16. E.H. Lennette, and R.L. Magoffin Virologic and immunologic aspects of major oral ulcerations J Am Dent Assoc 87 5 1973 1055 1073
17. Ship II, W.K. Ashe, and H.W. Scherp Recurrent "fever blister" and "canker sore". Tests for herpes simplex and other viruses with mammalian cell cultures Arch Oral Biol 3 1961 117 124
18. O. Donatsky, T. Justesen, K. Lind, and B.F. Vestergaard Microorganisms in recurrent aphthous ulcerations Scand J Dent Res 85 6 1977 426 433
19. A. Pedersen, and A. Hornsleth Recurrent aphthous ulceration: a possible clinical manifestation of reactivation of varicella zoster or cytomegalovirus infection J Oral Pathol Med 22 2 1993 64 68
20. F. Ghodratnama, M.P. Riggio, and D. Wray Search for human herpesvirus 6, human cytomegalovirus and varicella zoster virus DNA in recurrent aphthous stomatitis tissue J Oral Pathol Med 26 4 1997 192 197
21. J.M. Victoria, E. Kalapothakis, F. Silva Jde, and R.S. Gomez Helicobacter pylori DNA in recurrent aphthous stomatitis J Oral Pathol Med 32 4 2003 219 223
22. C. Birek, R. Grandhi, K. McNeill, D. Singer, G. Ficarra, and G. Bowden Detection of Helicobacter pylori in oral aphthous ulcers J Oral Pathol Med 28 5 1999 197 203
23. O. Donatsky, and G. Bendixen In vitro demonstration of cellular hypersensitivity to strep 2A in recurrent aphthous stomatitis by means of the leucocyte migration test Acta Allergol 27 2 1972 137 144
24. S.R. Porter, C. Scully, and A. Pedersen Recurrent aphthous stomatitis Crit Rev Oral Biol Med 9 3 1998 306 321
25. G. Stevenson Evidence for a negative correlation of recurrent aphthous ulcers with lactobacillus activity J La Dent Assoc 25 2 1967 5 7
26. A. Sun, J.G. Chang, C.T. Chu, B.Y. Liu, J.H. Yuan, and C.P. Chiang Preliminary evidence for an association of Epstein-Barr virus with pre-ulcerative oral lesions in patients with recurrent aphthous ulcers or Behcet's disease J Oral Pathol Med 27 4 1998 168 175
27. J.D. O'Duffy Behcet's syndrome N Engl J Med 322 5 1990 326 328
28. J.D. O'Duffy Vasculitis in Behcet's disease Rheum Dis Clin North Am 16 2 1990 423 431
29. I. Krause, Y. Uziel, and D. Guedj Mode of presentation and multisystem involvement in Behcet's disease: the influence of sex and age of disease onset J Rheumatol 25 8 1998 1566 1569
30. I. Krause, Y. Monselise, G. Milo, and A. Weinberger Anti-Saccharomyces cerevisiae antibodies - a novel serologic marker for Behcet's disease Clin Exp Rheumatol 20 4 Suppl 26 2002 S21 S24
31. H. Imai, M. Motegi, and N. Mizuki Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome): a case report and literature review Am J Med Sci 314 5 1997 330 332
32. R.L. Orme, J.J. Nordlund, L. Barich, and T. Brown The MAGIC syndrome (mouth and genital ulcers with inflamed cartilage) Arch Dermatol 126 7 1990 940 944
33. M.S. Greenberg, and A. Pinto Etiology and management of recurrent aphthous stomatitis Curr Infect Dis Rep 5 3 2003 194 198
34. K. Maeda, M. Okada, and T. Yao Intestinal and extraintestinal complications of Crohn's disease: predictors and cumulative probability of complications J Gastroenterol 29 5 1994 577 582
35. L. Halme, J.H. Meurman, and P. Laine Oral findings in patients with active or inactive Crohn's disease Oral Surg Oral Med Oral Pathol 76 2 1993 175 181
36. S.J. Schnitt, D.A. Antonioli, B. Jaffe, and M.A. Peppercorn Granulomatous inflammation of minor salivary gland ducts: a new oral manifestation of Crohn's disease Hum Pathol 18 4 1987 405 407
37. A.R. Kerr, and J.A. Ship Management strategies for HIV-associated aphthous stomatitis Am J Clin Dermatol 4 10 2003 669 680
38. F.J. Ramos-Gomez, C. Flaitz, P. Catapano, P. Murray, A.R. Milnes, and A. Dorenbaum Classification, diagnostic criteria, and treatment recommendations for orofacial manifestations in HIV-infected pediatric patients. Collaborative Workgroup on Oral Manifestations of Pediatric HIV Infection J Clin Pediatr Dent 23 2 1999 85 96
39. R.D. Lange, and J.B. Jones Cyclic neutropenia. Review of clinical manifestations and management Am J Pediatr Hematol Oncol 3 4 1981 363 367
40. G.S. Marshall, K.M. Edwards, J. Butler, and A.R. Lawton Syndrome of periodic fever, pharyngitis, and aphthous stomatitis J Pediatr 110 1 1987 43 46
41. M. Berlucchi, A. Meini, A. Plebani, M.G. Bonvini, D. Lombardi, and P. Nicolai Update on treatment of Marshall's syndrome (PFAPA syndrome): report of five cases with review of the literature Ann Otol Rhinol Laryngol 112 4 2003 365 369
42. M.F. Miller, A.A. Garfunkel, C. Ram, and Ship II Inheritance patterns in recurrent aphthous ulcers: twin and pedigree data Oral Surg Oral Med Oral Pathol 43 6 1977 886 891
43. L.R. Eversole Immunopathogenesis of oral lichen planus and recurrent aphthous stomatitis Semin Cutan Med Surg 16 4 1997 284 294
44. N.W. Savage, G.J. Seymour, and B.J. Kruger Expression of class I and class II major histocompatibility complex antigens on epithelial cells in recurrent aphthous stomatitis J Oral Pathol 15 4 1986 191 195
45. L. Jaber, A. Weinberger, T. Klein, I. Yaniv, and M. Mukamel Close association of HLA-B52 and HLA-B44 antigens in Israeli Arab adolescents with recurrent aphthous stomatitis Arch Otolaryngol Head Neck Surg 127 2 2001 184 187
46. G. Gallina, V. Cumbo, P. Messina, and C. Caruso HLA-A, B, C, DR, MT, and MB antigens in recurrent aphthous stomatitis Oral Surg Oral Med Oral Pathol 59 4 1985 364 370
47. D. Wray, T.P. Vlagopoulos, and R.P. Siraganian Food allergens and basophil histamine release in recurrent aphthous stomatitis Oral Surg Oral Med Oral Pathol 54 4 1982 388 395
48. A. Hasan, T. Shinnick, Y. Mizushima, R. van der Zee, and T. Lehner Defining a T-cell epitope within HSP 65 in recurrent aphthous stomatitis Clin Exp Immunol 128 2 2002 318 325
49. M.L. Pacor, G. Di Lorenzo, and N. Martinelli Results of double-blind placebo-controlled challenge with nickel salts in patients affected by recurrent aphthous stomatitis Int Arch Allergy Immunol 131 4 2003 296 300
50. K.D. Hay, and P.C. Reade The use of an elimination diet in the treatment of recurrent aphthous ulceration of the oral cavity Oral Surg Oral Med Oral Pathol 57 5 1984 504 507
51. B.B. Herlofson, and P. Barkvoll Sodium lauryl sulfate and recurrent aphthous ulcers. A preliminary study Acta Odontol Scand 52 5 1994 257 259
52. L. Chahine, N. Sempson, and C. Wagoner The effect of sodium lauryl sulfate on recurrent aphthous ulcers: a clinical study Compend Contin Educ Dent 18 12 1997 1238 1240
53. C.M. Healy, M. Paterson, S. Joyston-Bechal, D.M. Williams, and M.H. Thornhill The effect of a sodium lauryl sulfate-free dentifrice on patients with recurrent oral ulceration Oral Dis 5 1 1999 39 43
54. D.W. Thomas, J. Bagg, and D.M. Walker Characterisation of the effector cells responsible for the in vitro cytotoxicity of blood leucocytes from aphthous ulcer patients for oral epithelial cells Gut 31 3 1990 294 299
55. C.I. Hoover, J.A. Olson, and J.S. Greenspan Humoral responses and cross-reactivity to viridans streptococci in recurrent aphthous ulceration J Dent Res 65 8 1986 1101 1104
56. N.W. Savage, G.J. Seymour, and B.J. Kruger T-lymphocyte subset changes in recurrent aphthous stomatitis Oral Surg Oral Med Oral Pathol 60 2 1985 175 181
57. J.S. Greenspan, N. Gadol, and J.A. Olson Lymphocyte function in recurrent aphthous ulceration J Oral Pathol 14 8 1985 592 602
58. E.W. Bachtiar, S. Cornain, B. Siregar, and T.W. Raharjo Decreased CD4 + /CD8 + ratio in major type of recurrent aphthous ulcers: comparing major to minor types of ulcers Asian Pac J Allergy Immunol 16 2-3 1998 75 79
59. A. Pedersen, B. Klausen, H.P. Hougen, and J.P. Stenvang T-lymphocyte subsets in recurrent aphthous ulceration J Oral Pathol Med 18 1 1989 59 60
60. I.J. Buno, J.C. Huff, W.L. Weston, D.T. Cook, and S.L. Brice Elevated levels of interferon gamma, tumor necrosis factor alpha, interleukins 2, 4, and 5, but not interleukin 10, are present in recurrent aphthous stomatitis Arch Dermatol 134 7 1998 827 831
61. R. Hayrinen-Immonen, D. Nordstrom, M. Malmstrom, J. Hietanen, and Y.T. Konttinen Immune-inflammatory cells in recurrent oral ulcers (ROU) Scand J Dent Res 99 6 1991 510 518
62. A. Nolan, W.B. McIntosh, B.F. Allam, and P.J. Lamey Recurrent aphthous ulceration: vitamin B1, B2 and B6 status and response to replacement therapy J Oral Pathol Med 20 8 1991 389 391
63. D. Wray, M.M. Ferguson, D.K. Mason, A.W. Hutcheon, and J.H. Dagg Recurrent aphthae: treatment with vitamin B12, folic acid, and iron Br Med J 2 5969 1975 490 493
64. L. Endre Recurrent aphthous ulceration with zinc deficiency and cellular immune deficiency Oral Surg Oral Med Oral Pathol 72 5 1991 559 561
65. M.M. Ferguson, D. Wray, H.A. Carmichael, R.I. Russell, and F.D. Lee Coeliac disease associated with recurrent aphthae Gut 21 3 1980 223 226
66. R. Ferguson, M.K. Basu, P. Asquith, and W.T. Cooke Jejunal mucosal abnormalities in patients with recurrent aphthous ulceration Br Med J 1 6000 1976 11 13
67. D. Wray Gluten-sensitive recurrent aphthous stomatitis Dig Dis Sci 26 8 1981 737 740
68. D. Wray, M.M. Ferguson, W.A. Hutcheon, and J.H. Dagg Nutritional deficiencies in recurrent aphthae J Oral Pathol 7 6 1978 418 423
69. S.R. Porter, C. Scully, and S. Flint Hematologic status in recurrent aphthous stomatitis compared with other oral disease Oral Surg Oral Med Oral Pathol 66 1 1988 41 44
70. M. Ogura, T. Yamamoto, M. Morita, and T. Watanabe A case-control study on food intake of patients with recurrent aphthous stomatitis Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91 1 2001 45 49
71. R.S. Rogers 3rd, and K.P. Hutton Screening for haematinic deficiencies in patients with recurrent aphthous stomatitis Australas J Dermatol 27 3 1986 98 103
72. M. Soto Araya, G. Rojas Alcayaga, and A. Esguep Association between psychological disorders and the presence of oral lichen planus, burning mouth syndrome and recurrent aphthous stomatitis Med Oral 9 1 2004 1 7
73. A.L. McCann, and L. Bonci Maintaining women's oral health Dent Clin North Am 45 3 2001 571 601
74. M.F. Miller, and Ship II A retrospective study of the prevalence and incidence of recurrent aphthous ulcers in a professional population, 1958-1971 Oral Surg Oral Med Oral Pathol 43 4 1977 532 537
75. K. Gunduz, G. Ozturk, and E.Y. Sozmen Erythrocyte superoxide dismutase, catalase activities and plasma nitrite and nitrate levels in patients with Behcet disease and recurrent aphthous stomatitis Clin Exp Dermatol 29 2 2004 176 179
76. S. Boulinguez, S. Reix, and C. Bedane Role of drug exposure in aphthous ulcers: a case-control study Br J Dermatol 143 6 2000 1261 1265
77. S.S. Natah, R. Hayrinen-Immonen, J. Hietanen, M. Malmstrom, and Y.T. Konttinen Quantitative assessment of mast cells in recurrent aphthous ulcers (RAU) J Oral Pathol Med 27 3 1998 124 129
78. H.E. Schroeder, W. Muller-Glauser, and K. Sallay Pathomorphologic features of the ulcerative stage of oral aphthous ulcerations Oral Surg Oral Med Oral Pathol 58 3 1984 293 305
79. S.S. Natah, R. Hayrinen-Immonen, J. Hietanen, M. Malmstrom, and Y.T. Konttinen Factor XIIIa-positive dendrocytes are increased in number and size in recurrent aphthous ulcers (RAU) J Oral Pathol Med 26 9 1997 408 413
80. M.S. Greenberg Ulcerative, vesicular and bullous lesions M. Glick Burket's oral medicine 10th edition 2002 BC Decker Hamilton (Ontario, Canada) 50 84
81. J. Guggenheimer, V.J. Brightman, and Ship II Effect of chlortetracycline mouthrinses on the healing of recurrent aphthous ulcers: a double-blind controlled trial J Oral Ther Pharmacol 4 5 1968 406 408
82. E.A. Graykowski, and A. Kingman Double-blind trial of tetracycline in recurrent aphthous ulceration J Oral Pathol 7 6 1978 376 382
83. A.R. Kerr, C.A. Drexel, and A.I. Spielman The efficacy and safety of 50 mg penicillin G potassium troches for recurrent aphthous ulcers Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 6 2003 685 694
84. S. Silverman Jr., F. Lozada-Nur, and C. Migliorati Clinical efficacy of prednisone in the treatment of patients with oral inflammatory ulcerative diseases: a study of fifty-five patients Oral Surg Oral Med Oral Pathol 59 4 1985 360 363
85. A.V. Wahba-Yahav Pentoxifylline in intractable recurrent aphthous stomatitis: an open trial J Am Acad Dermatol 33 4 1995 680 682
86. J. Chandrasekhar, A.A. Liem, N.H. Cox, and A.W. Paterson Oxypentifylline in the management of recurrent aphthous oral ulcers: an open clinical trial Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87 5 1999 564 567
87. J. Katz, P. Langevitz, J. Shemer, S. Barak, and A. Livneh Prevention of recurrent aphthous stomatitis with colchicine: an open trial J Am Acad Dermatol 31 3 Pt 1 1994 459 461
88. V. Fontes, L. Machet, B. Huttenberger, G. Lorette, and L. Vaillant [Recurrent aphthous stomatitis: treatment with colchicine. An open trial of 54 cases] Ann Dermatol Venereol 129 12 2002 1365 1369
89. R. Tananis, S. DeRossi, T.P. Sollectio, and M.S. Greenberg Management of recurrent aphthous stomatitis with colchicine and pentoxifylline [abstract presented at the 54th annual meeting of the American Academy of Oral Medicine] Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89 2000 449
90. J. Revuz, J.C. Guillaume, and M. Janier Crossover study of thalidomide vs placebo in severe recurrent aphthous stomatitis Arch Dermatol 126 7 1990 923 927
91. J.M. Jacobson, J.S. Greenspan, and J. Spritzler Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group N Engl J Med 336 21 1997 1487 1493
92. M. Sarmadi, and J.A. Ship Refractory major aphthous stomatitis managed with systemic immunosuppressants: a case report Quintessence Int 35 1 2004 39 48
93. N.D. Robinson, and J. Guitart Recalcitrant, recurrent aphthous stomatitis treated with etanercept Arch Dermatol 139 10 2003 1259 1262
94. M.A. Scheinberg Treatment of recurrent oral aphthous ulcers with etanercept Clin Exp Rheumatol 20 5 2002 733 734