Specific regulation of gene expression by antisense nucleic acids: A summary of methodologies and associated problems

Artificial Organs

Volumn 20, Issue 8, 1996, Pages 836-848

  Kawasaki, Hiroaki ^a   Machida, Meiji ^a,b   Komatsu, Masaaki ^a   Li, Hai Ou ^a   Murata, Takehide ^a   Tsutsui, Hatsumi ^a   Fujita, Akiko ^a   Matsumura, Masatoshi ^a   Kobayashi, Yoshiro ^b   Taira, Kazunari ^a   Yokoyama, Kazunari K ^a,c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b TOHO UNIVERSITY   (Japan)

^c RIKENTsukuba Institute   (Japan)

Author keywords

Antisense RNA; Mechanism of antisense RNA; Medical therapeutics; Transcription factor, c myc

Indexed keywords

C (PROGRAMMING LANGUAGE); CYTOLOGY; GENE EXPRESSION REGULATION; GENE THERAPY; OLIGOMERS; TRANSCRIPTION; TRANSCRIPTION FACTORS; VIRUSES;

ANTISENSE; ANTISENSE RNA; HELIX BINDING; HL-60 CELLS; MECHANISM OF ANTISENSE RNA; MEDICAL THERAPEUTIC; TRANSCRIPTION FACTOR, C-MYC; TRIPLE HELIXES; ZINC FINGER PROTEIN;

RNA;

COMPLEMENTARY DNA; COMPLEMENTARY RNA; TRANSCRIPTION FACTOR;

ARTICLE; CELL STRAIN HL 60; GENE EXPRESSION; ONCOGENE C MYC; PRIORITY JOURNAL;

EID: 9444235050     PISSN: 0160564X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-1594.1996.tb04556.x     Document Type: Article

References (26)

1. Green PJ, Pines O, Inouye M. The role of antisense RNA in gene regulation. Annu Rev Biochem 1986;55:569-97.
2. Simons RW, Kleckner N. Biological regulation by antisense RNA in prokaryotes. Annu Rev Genet 1988;22:567-600.
3. Krinke L, Wuff DL. OOP RNA, produced from multicopy plasmids inhibits lamda ell gene expression by a divergent RNA transcript. Genes Dev 1987;1:1005-13.
4. Okamoto K, Freundlich M. Mechanism for the autogenous control of the crp operon: Transcriptional inhibition by a divergent RNA transcript. Proc Natl Acad Sci USA 1986; 83:5000-4.
5. Weintraub H, Izant KG, Harland RM. Antisense RNA as a molecular tool for genetic analysis. Trends Genet 1985;1: 22-5.
6. Zamecnik PC, Stephenson ML. Inhibition of Rouse sarcoma virus replication and cell transformation by a specific oligonucleotide Proc Natl Acad Sci USA 1987;75:280-4.
7. Stephenson ML, Zamecnik PC. Inhibition of Rouse sarcoma viral RNA translation by a specific oligonucleotide. Proc Natl Acad Sci USA 1978;75:285-8.
8. Helene C, Toulme J-J. Specific regulation of gene expression by antisense. sense and antigene nucleic acids. Biochim Biophys Acta 1990;1049:99-125.
9. Stein CA, Cheng Y-C. Antisense oligonucleotides as therapeutic agents: Is the bullet really magical? Science 1993;261: 1004-12.
10. Sambrook O, Fritsch EF, Maniatis T. Molecular cloning: A laboratory manual, 2nd ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, 1989.
11. Boles C, Hogan M. DNA structure equilibria in the human c-myc gene. Biochemistry 1987;26:367-76.
12. Jones TR, Cole MC. Rapid cytoplasmic turnover of c-myc mRNA: Requirement of the 3′ untranslated sequences. Mol Cell Biol 1987;3:4513-21.
13. Yokoyama K, Imamoto F. Transcriptional control of the endogenous myc protooncogene by antisense RNA. Proc Natl Acad Sci USA 1987;84:7363-67.
14. Yokoyama K. Transcriptional regulation of c-myc protooncogene by antisense RNA. In: Wickstrom E, ed. Prospects for antisense nucleic acid therapy of cancer and AIDS. New York: Wiley-Liss, 1991:35-51.
15. Yokoyama K. Antisense RNA induces a nuclear transcription factor to repress the expression of endogenous myc gene. In: Murray JHH, ed. Antisense RNA and DNA. New York: Wiley-Liss, 1992:335-52.
16. Yokoyama K. Antisense application of antisense oligomers against cancers and viral infections. RIKEN Rev 1994;6: 29-30.
17. Yokoyama K. Antisense strategy: A medical application of therapeutic agents against cancers and viral infections. Now and Future 1993;9:11-6.
18. Siebenlist U, Henninghausen L, Battey J, Lader P. Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma. Cell 1984;37:381-91.
19. Hay NJ, Bishop M, Levans D. Regulatory elements that modulate expression of human c-myc. Genes Dev 1987;1: 659-71.
20. Pyre JJ, Moberg KH, Hall DJ. Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter. Biochemistry 1992;31:4102-10.
21. Logan T, Pyrc J, Hall DJ. Physical characterization of a factor related to the c-myc/insulin promoter-binding protein ZF87/Pur-1. Biochem Biophys Res Commun 1993;3:1204-9.
22. Bossone SA, Asselin C, Patel AJ, Marcu KB. MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination. Proc Nutl Acad Sci USA 1992;89:7452-6.
23. Kennedy GC, Rutter WJ. Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells. Proc Natl Acad Sci USA 1992; 89:11498-502.
24. Koyago-Nakagawa N, Nisida J, Baldwin D, Arai K-I, Yokota T. Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter. Mol Cell Biol 1994;14:5099-107.
25. Pavletich NP, Pabo CO. Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1Å. Science 1991;252:809-17.
26. Postel EH, Mango SE, Flint SJ. A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor. Mol Cell Biol 1989;9:5123-33.