Structures of the Klebsiella aerogenes urease apoenzyme and two active- site mutants

Biochemistry

Volumn 35, Issue 33, 1996, Pages 10616-10626

  Jabri, Evelyn ^a,b   Andrew Karplus, P ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOENZYME; BACTERIAL ENZYME; MUTANT PROTEIN; UREASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBUNIT; KLEBSIELLA AEROGENES; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; KLEBSIELLA PNEUMONIAE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; UREASE;

EID: 9444234584     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960424z     Document Type: Article

References (50)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E., & Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410.
2. Banning, M. M., Kuo, J. M., Raushel, F. M., & Holden, H. M. (1995) Biochemistry 34, 7973-7978.
3. Blanchard, A. (1990) Mol. Microbiol. 4, 669-676.
4. Brünger, A. T., Kmkowski, A., & Erickson, J. W. (1990) Acta Crystallogr. A46, 585-593.
5. Chan, M. K., Muklund, S., Kletzin, A., Adams, M. W. W., & Rees, D. C. (1995) Science 267, 1463-1469.
6. Chen, Y. Y., Clancy, K. A., & Burne, R. A. (1996) Infect. Immun. 64, 585-592.
7. Clayton, C. L., Pallen, M., Kleanthous, H., Wren, B. W., & Tabaqchali, S. (1990) Nucleic Acids Res. 18, 362.
8. Connolly, M. L. (1983) Science 221, 709-713.
9. Devereux, J., Haiberli, P., & Smithies, O. (1984) Nucleic Acids Res. 12, 387-395.
10. Dixon, N. E., Gazzola, C., Asher, C. J., Lee, D. S., Blakeley, R. L., & Zerner, B. (1980) Can. J. Biochem. 58, 474-480.
11. Ferrero, R. L., & Labigne, A. (1993) Mol. Microbiol. 9, 323-333.
12. Ferrin, T. E. (1988) J. Mol. Graphics 6, 13-27.
13. Hausinger, R. P. (1993) in Biochemistry of Nickel, pp 23-50, Plenum Press, New York.
14. Howard, A. J., Nielson, C., & Xuong, N. H. (1985) Methods Enzymol. 114, 452-472.
15. Jabri, E. (1995) Crystal structure of the holo-, apo-, and three active site mutants of urease from Klebsiella aerogenes, Ph.D. Thesis, Cornell University, Ithaca, NY.
16. Jabri, E., Lee, M. H., Hausinger, R. P., & Karplus, P. A. (1992) J. Mol. Biol. 227, 934-937.
17. Jabri, E., Carr, M. B., Hausinger, R. P., & Karplus, P. A. (1995) Science 268, 998-1004.
18. Jones, B. D., & Mobley, H. L. T. (1989) J. Bacteriol. 171, 6414-6422.
19. Jose, J., Christians, S., Rosenstein, R., Götz, F., & Kaltwasser, H. (1991) FEMS Microbiol. Lett. 80, 277-282.
20. Kabsch, W., & Sander, C. (1983) Biopolymers 22, 2577-2637.
21. Laskowski, R. A., MacArthur, M. W., Moss, D. S., & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
22. Lee, M. H., Mulrooney, S. B., & Hausinger, R. P. (1990) J. Bacteriol. 172, 4427-4431.
23. Lorimer, G. H., Badger, M. R., & Andrews, T. J. (1976) Biochemistry 15, 529-536.
24. Luzzati, P. V. (1952) Acta Crystallogr. 5, 802-810.
25. Maeda, M., Hidaka, M., Nakamura, A., Masaki, H., & Uozumi, T. (1994) J. Bacteriol. 176, 432-442.
26. Martin, P. R., & Hausinger, R. P. (1992) J. Biol. Chem. 267, 20024-20027.
27. McDonald, I. K., Naylor, D. N., Jones, D. T., & Thornton, J. M. (1993) HBPlus, Department of Biochemistry and Molecular Biology, University College, London.
28. Miksch, G., Arnold, W., Lentzsch, P., Priefer, U. B., & Puhler, A. (1994) Mol. Gen. Genet. 242, 539-550.
29. Mobley, H. L. T., & Hausinger, R. P. (1989) Microbiol. Rev. 53, 85-108.
30. Mobley, H. L. T., Island, M. D., & Hausinger, R. P. (1996) Microbiol. Rev. (in press).
31. Moncrief, M. C., & Hausinger, R. P. (1996) in Mechanisms of Metallocenter Assembly (Hausinger, R. P., Eichhorn, G. L., & Marzilli, L. G., Eds.) pp 151-171. Elsevier Press, New York.
32. Mulrooney, S. B., & Hausinger, R. P. (1990) J. Bacteriol. 172, 5837-5843.
33. Neyrolles, O., Ferris, S., Behbahani, N., Montagnier, L., & Blanchard, A. (1996) J. Bacteriol. 178, 647-655.
34. Otwinowski, Z. (1993) in Data Collection and Processing (Sawyer, L., Isaacs, N., & Bailey, S. S., Eds.) pp 55-62, SERC Daresbury Laboratory, Warrington, U.K.
35. Park, I.-S., & Hausinger, R. P. (1993a) Protein Sci. 2, 1034-1041.
36. Park, I.-S., & Hausinger, R. P. (1993b) J. Protein Chem. 12, 51-56.
37. Park, I.-S., & Hausinger, R. P. (1995) Science 267, 1156-1158.
38. Ramachandran, G. N., & Sasisekharan, V. (1968) Adv. Protein Chem. 23, 283-427.
39. Reyrat, J. M., Berthet, F. X., & Gicquel, B. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 8768-8772.
40. Richards, F. M. (1977) Annu. Rev. Biophys. Bioeng. 6, 151-176.
41. Riddles, P. W., Whan, V., Blakeley, R. L., & Zerner, B. (1992) Gene (Amsterdam) 108, 265-268.
42. Rozwarski, D. A., Diederichs, K., Hecht, R., Boone, T., & Karplus, P. A. (1996) Proteins: Struct., Funct., Genet. (in press).
43. Sack, J. S. (1988) J. Mol. Graphics 6, 224-225.
44. Skurnik, M., Batsford, S., Mertz, A., Schiltz, E., & Toivanen, P. (1993) Infect. Immun. 61, 2498-2504.
45. Solnick, J. V., O'Rourke, J., Lee, A., & Tompkins, L. S. (1994) Infect. Immun. 92, 1631-1638.
46. Stemmler, A. J., Kampf, J. W., Kirk, M. L., & Pecoraro, V. L. (1995) J. Am. Chem. Soc. 117, 6368-6369.
47. Wages, H. E., Taft, K. L., & Lippard, S. J. (1993) Inorg. Chem. 32, 4985-4987.
48. Wilson, D. K., & Quiocho, F. A. (1993) Biochemistry 32, 1689-1694.
49. Wilson, D. K., Rudolph, F. B., & Quiocho, F. A. (1991) Science 252, 1278-1284.
50. Zerner, B. (1991) Bioorg. Chem. 19, 116-131.