Lymphokine release during co-culture of human lympho mononuclear cells and fresh or cultured human, porcine and bovine pancreatic islets

Acta Diabetologica

Volumn 33, Issue 2, 1996, Pages 122-125

  Giannarelli, R ^a   Ferdeghini, M ^b   Arvia, C ^a   Consolini, R ^b   Marchetti, P ^a   Coppelli, A ^a   Prontera, C ^b   Legitimo, A ^b   Carmellini, M ^b   Mosca, F ^b   Navalesi, R ^a  

^a Ist Clinica Medica II   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

Lymphokines; Pancreatic islets

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; LYMPHOKINE;

ANIMAL CELL; ARTICLE; CATTLE; CELL CULTURE; CONTROLLED STUDY; HELPER CELL; HUMAN; HUMAN CELL; MONONUCLEAR CELL; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; SWINE;

EID: 9444221452     PISSN: 09405429     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00569422     Document Type: Article

References (23)

1. Krensky AM, Weiss A, Crabtree G, Davis MM, Parham P, T-lymphocyte-antigen interactions in transplant rejection. N Engl J Med 322:510-537, 1990
2. Nickerson P, Steurer W, Steiger J, Zheng X, Steele AW, Strom TB, Cytokines and the Th1/Th2 paradigm in transplantation. Curr Opin Immunol 6:757-764, 1994
3. Janeway CA Jr, Bottomly K, Signals and sign for lymphocyte responses. Cell 76:275-285, 1994
4. Vossan ACT, Savelkoul HFJ, Cytokines in clinical and experimental transplantation. Mediators Inflammation 3:403-410, 1994
5. Wren SM, Wang SC, Thai NL, Conrad B, Hoffman RA, Fung JJ, Simmons RL, Ildstad S, Evidence for early Th2 T cell predominance in xenoreactivity. Transplantation 56:905-911, 1993
6. Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Boyle JP, Falqui L, Marchetti P, Ricordi C, Gingerich RL, Jaffe AS, Cryer PE, Hanto DW, Anderson CB, Flye MW, Results of our first nine intraportal islet allografts in type 1, insulin-dependent diabetic patients. Transplantation 51:76-85, 1991
7. Warnock GL, Kneteman NM, Ryan E, Seelis REA, Rabinovitch A, Rajotte RV, Normoglycaemia after transplantation of freshly and cryopreserved pancreatic islets in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 34:55-58, 1991
8. Alejandro R, Burke G, Shapiro ET, Strasser S, Nery J, Ricordi C, Esquenazi V, Miller J, Mintz DH, Intraportal islet allografts in type I diabetes mellitus. Transplant Proc 24:959-960, 1992
9. Ricordi C, Tzakis A, Carroll P, Zeng Y, Rilo HLR, Alejandro R, Shapiro R, Fung JJ, Demetris AJ, Bereiter DR, Mintz DH, Starzl TE, Human islet transplantation in 18 diabetic patients. Transplant Proc 24:961-962, 1992
10. Socci C, Falqui L, Davalli AM, Ricordi C, Braghi S, Bertuzzi F, Maffi P, Secchi A, Gavazzi F, Freschi M, Magistretti P, Socci S, Vignali A, Di Carlo V, Pozza G, Fresh human islet transplantation to replace pancreatic endocrine function in type I diabetic patients. Acta Diabetol 28:151-157, 1991
11. Ricordi C, Finke EH, Lacy PE, A method for the mass isolation of islets from the adult pig pancreas. Diabetes 35:649-652, 1986
12. Marchetti P, Finke EH, Gerasimidi-Vazeou A, Falqui L, Scharp DW, Lacy PE, Automated large-scale isolation, in vitro function and xenotransplantation of porcine islets of Langerhans. Transplantation 52:209-213, 1991
13. Calafiore R, Calcinaro F, Basta G, Pietropaolo M, Falorni A, Piermattei M, Brunetti P, A method for the massive separation of highly purified, adult porcine islets of Langerhans. Metabolism 39:175, 1990
14. Groth CG, Korsgren D, Tibell A, Tollemar J, Möller E, Bolinder J, Östman J, Reinholt FP, Hellerström C, Andersson A, Transplantation of porcine fetal pancreas to diabetic patients. Lancet 344:1402-1404, 1994
15. Marchetti P, Giannarelli R, Cosimi S, Masiello P, Coppelli A, Viacava P, Navalesi R, Massive isolation, morphological and functional characterization, and xenotransplantation of bovine pancreatic islets. Diabetes 44:375-380, 1995
16. Boyum A, Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest 21:77-89, 1968
17. Marchetti P, Giannarelli R, Giusti L, Trincavelli L, Martini C, Carmellini M, Lucacchini A, Mosca F, Navalesi R, Peripheral benzodiazepine receptors in isolated human pancreatic islets. Diabetes 44 (Suppl 1):248A, 1995
18. Coppelli A, Arvia C, Giannarelli R, Marchetti P, Viacava P, Naccarato AG, Lorenzetti M, Cosimi S, Cecchetti P, Navalesi R, Long-term survival and function of isolated bovine pancreatic islets maintained in different culture media. Acta Diabetol 33:166-168, 1996
19. Coppelli A, Giannarelli R, Marchetti P, Tellini C, Del Guerra S, Lupi R, Lorenzetti M, Cosimi S, Masiello P, Fierabracci V, Novelli M, Carmellini M, Mosca F, Lencioni C, Cionini R, Navalesi R, Preparation and storage by culture of isolated human islets. Horm Metab Res 28:55(A), 1996
20. Heiser A, Ulrichs K, Eckstein V, Muller-Ruchholtz X, Xenogeneic cellular response of human lymphocytes to porcine lymphocytes and isolated porcine pancreatic islets. Transplant Proc 24:2881-2882, 1992
21. Kirk AD, Ra LI, Kirch MS, Abemethy KA, Doyle C, Bollinger RR, The human antiporcine cellular repertoire. Transplantation 55:924-931, 1993
22. Murray AC, Kodadount MM, Pober JS, Bothwell ALM, Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligand for human CD2 and CD28. Immunity 1:57-63, 1994
23. Gill RG, The role of direct and indirect antigen presentation in the response to islet xenograft. Transplant Proc 24:642-643, 1992