메뉴 건너뛰기




Volumn 137, Issue 6, 1996, Pages 2480-2489

Interleukin-1β stimulates sphingomyelin hydrolysis in cultured granulosa cells: Evidence for a regulatory role of ceramide on progesterone and prostaglandin biosynthesis

Author keywords

[No Author keywords available]

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; BUTYRYL CYCLIC AMP; CERAMIDE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; FOLLITROPIN; INTERLEUKIN 1BETA; PROGESTERONE; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; STEROID DELTA ISOMERASE;

EID: 9344265205     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.6.8641202     Document Type: Article
Times cited : (64)

References (54)
  • 1
    • 0023944339 scopus 로고
    • Tumor necrosis, cachexia, shock and inflammation: A common mediator
    • Beutler B, Cerami A 1988 Tumor necrosis, cachexia, shock and inflammation: a common mediator. Annu Rev Biochem 57:505-518
    • (1988) Annu Rev Biochem , vol.57 , pp. 505-518
    • Beutler, B.1    Cerami, A.2
  • 2
    • 0023953471 scopus 로고
    • Biology of interleukin-1
    • Dinarello CA 1988 Biology of interleukin-1. FASEB J 2:108-115
    • (1988) FASEB J , vol.2 , pp. 108-115
    • Dinarello, C.A.1
  • 3
    • 0024603761 scopus 로고
    • IL-1 and its biologically related cytokines
    • Dinarello CA, 1989 IL-1 and its biologically related cytokines. Adv Immunol 44:153-205
    • (1989) Adv Immunol , vol.44 , pp. 153-205
    • Dinarello, C.A.1
  • 4
    • 0025779160 scopus 로고
    • Tumor necrosis factor-α. New insights into the molecular mechanisms of its multiple actions
    • Vilceck J, Lee TH 1991 Tumor necrosis factor-α. New insights into the molecular mechanisms of its multiple actions. J Biol Chem 266: 7313-7316
    • (1991) J Biol Chem , vol.266 , pp. 7313-7316
    • Vilceck, J.1    Lee, T.H.2
  • 5
    • 0026056197 scopus 로고
    • Blocking interleukin-1: Interleukin 1 receptor antagonist in vivo and in vitro
    • Dinarello CA, Thomson RC 1991 Blocking interleukin-1: Interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today 12: 404-410
    • (1991) Immunol Today , vol.12 , pp. 404-410
    • Dinarello, C.A.1    Thomson, R.C.2
  • 6
    • 0025219908 scopus 로고
    • Interleukin-1 signal transduction increases GTP binding and hydrolysis in membranes of a murine thymoma line (EL4)
    • O'Neill LA, Bird TA, Gearing AJH, Saklatvala J 1990 Interleukin-1 signal transduction increases GTP binding and hydrolysis in membranes of a murine thymoma line (EL4). J Biol Chem 265:3146-3152
    • (1990) J Biol Chem , vol.265 , pp. 3146-3152
    • O'Neill, L.A.1    Bird, T.A.2    Gearing, A.J.H.3    Saklatvala, J.4
  • 7
    • 0026669426 scopus 로고
    • Signal transduction by tumor necrosis factorα is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line MC3T3-E1
    • Yanaga F, Abe M, Koga T, Hirata M 1992 Signal transduction by tumor necrosis factorα is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line MC3T3-E1. J Biol Chem 267:5114-5121
    • (1992) J Biol Chem , vol.267 , pp. 5114-5121
    • Yanaga, F.1    Abe, M.2    Koga, T.3    Hirata, M.4
  • 8
    • 0023809589 scopus 로고
    • Interleukin-1 stimulates diacylglycerol production in T lymphocytes
    • Rossoff PM, Savage N, Dinarello CA 1988 Interleukin-1 stimulates diacylglycerol production in T lymphocytes. Cell 54:73-81
    • (1988) Cell , vol.54 , pp. 73-81
    • Rossoff, P.M.1    Savage, N.2    Dinarello, C.A.3
  • 9
    • 0026458406 scopus 로고
    • TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced acidic sphingomyelin breakdown
    • Schütze S, Potthoff K, Machleidt T, Bercovic D, Wiegman K, Krönke M 1992 TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced acidic sphingomyelin breakdown. Cell 71:765-776
    • (1992) Cell , vol.71 , pp. 765-776
    • Schütze, S.1    Potthoff, K.2    Machleidt, T.3    Bercovic, D.4    Wiegman, K.5    Krönke, M.6
  • 10
    • 0026726492 scopus 로고
    • 2 production and sphingomyelin metabolism: Evidence for regulation of cydooxygenase gene expression by sphingosine and ceramide
    • 2 production and sphingomyelin metabolism: evidence for regulation of cydooxygenase gene expression by sphingosine and ceramide. J Biol Chem 267:2004-20050
    • (1992) J Biol Chem , vol.267 , pp. 2004-20050
    • Ballou, L.R.1    Chao, C.P.2    Holness, M.A.3    Barker, S.C.4    Raghow, R.5
  • 11
    • 0026735823 scopus 로고
    • Ceramide: A novel second messenger
    • Kolesnick RN 1992 Ceramide: a novel second messenger. Trends Cell Biol 2:232-236
    • (1992) Trends Cell Biol , vol.2 , pp. 232-236
    • Kolesnick, R.N.1
  • 12
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • Hannun YU 1994 The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269:3125-3128
    • (1994) J Biol Chem , vol.269 , pp. 3125-3128
    • Hannun, Y.U.1
  • 13
    • 0028297068 scopus 로고
    • The sphingomyelin pathway in tumor necrosis factor and IL-1 signalling
    • Kolesnick RN, Golde DW 1994 The sphingomyelin pathway in tumor necrosis factor and IL-1 signalling. Cell 77:325-328
    • (1994) Cell , vol.77 , pp. 325-328
    • Kolesnick, R.N.1    Golde, D.W.2
  • 14
    • 0029391135 scopus 로고
    • Signaling through the sphingomyelin pathway
    • Zhang Y, Kolesnick R 1995 Signaling through the sphingomyelin pathway. Endocrinology 136:4157-4160
    • (1995) Endocrinology , vol.136 , pp. 4157-4160
    • Zhang, Y.1    Kolesnick, R.2
  • 15
    • 0025128122 scopus 로고
    • The potential relevance of cytokines to ovarian physiology: The emerging role of resident ovarian cells of the white blood series
    • Adashi EY 1990 The potential relevance of cytokines to ovarian physiology: the emerging role of resident ovarian cells of the white blood series. Endocr Rev 11:454-464
    • (1990) Endocr Rev , vol.11 , pp. 454-464
    • Adashi, E.Y.1
  • 16
    • 0026745038 scopus 로고
    • Intraovarian regulation: Peptidergic signaling systems
    • Adashi EY, Rohan RM 1991 Intraovarian regulation: peptidergic signaling systems. Trends Endocrinol Metab 3:243-248
    • (1991) Trends Endocrinol Metab , vol.3 , pp. 243-248
    • Adashi, E.Y.1    Rohan, R.M.2
  • 17
    • 0025727034 scopus 로고
    • Cytokines in endocrinology: Their role in health and disease
    • Kennedy RL, Hones TH 1991 Cytokines in endocrinology: their role in health and disease. J Endocrinol 129:167-168
    • (1991) J Endocrinol , vol.129 , pp. 167-168
    • Kennedy, R.L.1    Hones, T.H.2
  • 19
    • 0028590162 scopus 로고
    • Hormonal control of gene expression in the ovary
    • Richards JS 1994 Hormonal control of gene expression in the ovary. Endocr Rev 15:725-751
    • (1994) Endocr Rev , vol.15 , pp. 725-751
    • Richards, J.S.1
  • 20
    • 0026650909 scopus 로고
    • Interleukin-1 stimulates prostaglandin biosynthesis: Evidence for heterologous contact-independent cell-cell interaction
    • Kokia E, Hurwitz A, Ricciarelli E, Tedeschi C, Resnick CE, Mitchel MD, Adashi EY 1992 Interleukin-1 stimulates prostaglandin biosynthesis: evidence for heterologous contact-independent cell-cell interaction. Endocrinology 130:3095-3097
    • (1992) Endocrinology , vol.130 , pp. 3095-3097
    • Kokia, E.1    Hurwitz, A.2    Ricciarelli, E.3    Tedeschi, C.4    Resnick, C.E.5    Mitchel, M.D.6    Adashi, E.Y.7
  • 21
    • 0018827831 scopus 로고
    • Ovulation: An inflammatory reaction
    • Espey LL 1980 Ovulation: an inflammatory reaction. Biol Reprod 22:73-106
    • (1980) Biol Reprod , vol.22 , pp. 73-106
    • Espey, L.L.1
  • 22
    • 0021691796 scopus 로고
    • Hormonal regulation of the differentiation of cultured granulosa cells
    • Hsueh AJW, Adahsi AY, Jones PBC, Welsh TH 1984 Hormonal regulation of the differentiation of cultured granulosa cells. Endocr Rev 5:76-127
    • (1984) Endocr Rev , vol.5 , pp. 76-127
    • Hsueh, A.J.W.1    Adahsi, A.Y.2    Jones, P.B.C.3    Welsh, T.H.4
  • 24
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen MB, Nielsen SE, Beg K 1989 Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Inmmunol Methods 119:203-210
    • (1989) J Inmmunol Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, S.E.2    Beg, K.3
  • 26
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction
    • Chomczynski P, Sacchi N 1987 Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem 162:156-159
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 27
    • 0025993493 scopus 로고
    • Cellular localization and hormonal regulation of follicle stimulating hormone receptor RNAs in the rat ovary
    • Camp TA, Rahal JO, Mayo KE 1991 Cellular localization and hormonal regulation of follicle stimulating hormone receptor RNAs in the rat ovary. Mol Endocrinol 5:1405-1417
    • (1991) Mol Endocrinol , vol.5 , pp. 1405-1417
    • Camp, T.A.1    Rahal, J.O.2    Mayo, K.E.3
  • 28
    • 0028228977 scopus 로고
    • 17-20 Lyase, and P450 aromatase in fetal mouse gonads
    • 17-20 Lyase, and P450 aromatase in fetal mouse gonads. Endocrinology 135:262-268
    • (1994) Endocrinology , vol.135 , pp. 262-268
    • Greco, T.L.1    Payne, A.2
  • 29
    • 0028301987 scopus 로고
    • Tyrosine kinase inhibitor AG18 arrests follicle stimulating hormone-induced granulosa cell differentiation: Use of reverse transcriptase-polymerase chain reaction assay for multiple messenger ribonucleic acid
    • Orly J, Rei Z, Greenberg NM, Richards JS 1994 Tyrosine kinase inhibitor AG18 arrests follicle stimulating hormone-induced granulosa cell differentiation: use of reverse transcriptase-polymerase chain reaction assay for multiple messenger ribonucleic acid. Endocrinology 134:2336-2346
    • (1994) Endocrinology , vol.134 , pp. 2336-2346
    • Orly, J.1    Rei, Z.2    Greenberg, N.M.3    Richards, J.S.4
  • 30
    • 0028073309 scopus 로고
    • Optimized chemiluminescent detection of DNA amplified in the exponential phase of PCR
    • Su X, Sullivan TF, Burstjan S, Berman SA 1994 Optimized chemiluminescent detection of DNA amplified in the exponential phase of PCR. BioTechniques 17:734-736
    • (1994) BioTechniques , vol.17 , pp. 734-736
    • Su, X.1    Sullivan, T.F.2    Burstjan, S.3    Berman, S.A.4
  • 31
    • 0025857560 scopus 로고
    • Prostaglandin endoperoxide synthase: Regulation of enzyme expression
    • DeWitt DL 1991 Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim Biophys Acta 1083:121-134
    • (1991) Biochim Biophys Acta , vol.1083 , pp. 121-134
    • DeWitt, D.L.1
  • 32
    • 0027076645 scopus 로고
    • Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolisacharide
    • Lee SH, Soyoola E, Chanmugan P, Sun H, Zhong H, Liou S, Simmons D, Hwang D 1992 Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolisacharide. J Biol Chem 267:25934-25938
    • (1992) J Biol Chem , vol.267 , pp. 25934-25938
    • Lee, S.H.1    Soyoola, E.2    Chanmugan, P.3    Sun, H.4    Zhong, H.5    Liou, S.6    Simmons, D.7    Hwang, D.8
  • 33
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • Xie W, Chipman JG, Robertson DL, Erikson RL, Simmons DL 1991 Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88:2692-2696
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.L.4    Simmons, D.L.5
  • 34
    • 0026749603 scopus 로고
    • The human intraovarian interleukin-1 (IL-1) system: Highly-compartmentalized and hormonally-dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist
    • Hurwitz A, Loukides J, Ricciarelli E, Botero L, Katz E, McAllister JM, Garcia JA, Rohan R, Adashi EY, Hernandez ER 1992 The human intraovarian interleukin-1 (IL-1) system: highly-compartmentalized and hormonally-dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist. J Clin Invest 89:1746-1754
    • (1992) J Clin Invest , vol.89 , pp. 1746-1754
    • Hurwitz, A.1    Loukides, J.2    Ricciarelli, E.3    Botero, L.4    Katz, E.5    McAllister, J.M.6    Garcia, J.A.7    Rohan, R.8    Adashi, E.Y.9    Hernandez, E.R.10
  • 35
    • 0023542735 scopus 로고
    • Interleukin-1 inhibits follicle stimulating hormone-induced differentiation in rat granulosa cells
    • Gottschall PE, Uehara A, Hoffmann ST, Arimura A 1987 Interleukin-1 inhibits follicle stimulating hormone-induced differentiation in rat granulosa cells. Biochem Biophys Res Commun 149:502-509
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 502-509
    • Gottschall, P.E.1    Uehara, A.2    Hoffmann, S.T.3    Arimura, A.4
  • 36
    • 0024449750 scopus 로고
    • Interleukin-1β is more potent than interleukin-α in suppressing follicle stimulating hormone-induced differentiation ovarian granulosa cells
    • Gottschall PE, Katsuura G, Arimura A 1989 Interleukin-1β is more potent than interleukin-α in suppressing follicle stimulating hormone-induced differentiation ovarian granulosa cells. Biochem Biophys Res Commun 163:764-770
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 764-770
    • Gottschall, P.E.1    Katsuura, G.2    Arimura, A.3
  • 37
    • 0024565282 scopus 로고
    • Effects of interleukin 1, 2, and 3 on follicle-stimulating hormone-induced differentiation of rat granulosa cells in culture
    • Kasson B, Gorospe W 1989 Effects of interleukin 1, 2, and 3 on follicle-stimulating hormone-induced differentiation of rat granulosa cells in culture. Mol Cell Endocrinol 62:103-111
    • (1989) Mol Cell Endocrinol , vol.62 , pp. 103-111
    • Kasson, B.1    Gorospe, W.2
  • 38
    • 0026675659 scopus 로고
    • Intracellular signalling in the gonads
    • Leung PCK, Steele GL 1992 Intracellular signalling in the gonads. Endocr Rev 13:476-499
    • (1992) Endocr Rev , vol.13 , pp. 476-499
    • Leung, P.C.K.1    Steele, G.L.2
  • 39
    • 0024268468 scopus 로고
    • Discordance in the effect of IL-1 on rat granulosa cell differentiation induced by follicle stimulating hormone or activators of adenylate cyclase
    • Gottschall PE, Katsuura G, Hoffmann ST, Arimura A 1988 Discordance in the effect of IL-1 on rat granulosa cell differentiation induced by follicle stimulating hormone or activators of adenylate cyclase. Biol Reprod 39:1074-1085
    • (1988) Biol Reprod , vol.39 , pp. 1074-1085
    • Gottschall, P.E.1    Katsuura, G.2    Hoffmann, S.T.3    Arimura, A.4
  • 40
    • 0024346282 scopus 로고
    • Inhibitory effect of interleukin-1 on luteinizing hormone-stimulated 3′,5′-monophosphate accumulation by culture porcine granulosa cells
    • Fukuoka M, Taii S, Yasuda K, Takakura K, Mori T 1989 Inhibitory effect of interleukin-1 on luteinizing hormone-stimulated 3′,5′-monophosphate accumulation by culture porcine granulosa cells. Endocrinology 125:136-143
    • (1989) Endocrinology , vol.125 , pp. 136-143
    • Fukuoka, M.1    Taii, S.2    Yasuda, K.3    Takakura, K.4    Mori, T.5
  • 42
    • 0023968630 scopus 로고
    • Primary structure of prostaglandin G/H synthase from sheep seminal gland determined from complementary DNA sequence
    • De Witt DL, Smith WL 1988 Primary structure of prostaglandin G/H synthase from sheep seminal gland determined from complementary DNA sequence. Proc Natl Acad Sci USA 85:1412-1416
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1412-1416
    • De Witt, D.L.1    Smith, W.L.2
  • 43
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor-promoter inducible mRNA from Swiss 3T3 cells encodes a novel prostglandin synthase/cyclooxygenase homologue
    • Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR 1991 TIS10, a phorbol ester tumor-promoter inducible mRNA from Swiss 3T3 cells encodes a novel prostglandin synthase/cyclooxygenase homologue. J Biol Chem 266:12866-12872
    • (1991) J Biol Chem , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 44
    • 0026774117 scopus 로고
    • Hormonal regulation of messenger ribonucleic acid encoding a novel isoform of prostaglandin endoperoxide H synthase in rat preovulatory follicles: Induction in vivo and in vitro
    • Sirois J, Simmons DL, Richards JS 1992 Hormonal regulation of messenger ribonucleic acid encoding a novel isoform of prostaglandin endoperoxide H synthase in rat preovulatory follicles: induction in vivo and in vitro. J Biol Chem 267:11586-11592
    • (1992) J Biol Chem , vol.267 , pp. 11586-11592
    • Sirois, J.1    Simmons, D.L.2    Richards, J.S.3
  • 45
    • 0026633391 scopus 로고
    • Induction of prostaglandin endoperoxide H synthase in rat preovulatory follicles by gonadotropin-releasing hormone
    • Wong WYL, Richards JS 1992 Induction of prostaglandin endoperoxide H synthase in rat preovulatory follicles by gonadotropin-releasing hormone. Endocrinology 130:3512-3521
    • (1992) Endocrinology , vol.130 , pp. 3512-3521
    • Wong, W.Y.L.1    Richards, J.S.2
  • 46
    • 0028970145 scopus 로고
    • Luteinizing hormone induces prostaglandin endoperoxide synthase-2 and luteinization in vitro by A-kinase and C-kinase pathways
    • Morris JK, Richards JS 1995 Luteinizing hormone induces prostaglandin endoperoxide synthase-2 and luteinization in vitro by A-kinase and C-kinase pathways. Endocrinology 136:1349-1558
    • (1995) Endocrinology , vol.136 , pp. 1349-1558
    • Morris, J.K.1    Richards, J.S.2
  • 47
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones DA, Carlton DP, Mc Intyre TM, Zimmerman GA, Prescott SM 1993 Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 268:9049-9054
    • (1993) J Biol Chem , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    Mc Intyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 48
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin signalling pathway in a cell-free system by interleukin 1β
    • Mathias S, Younes A, Kan CC, Ordlow I, Joseph C, Kolesnick R 1993 Activation of the sphingomyelin signalling pathway in a cell-free system by interleukin 1β. Science 259:519-522
    • (1993) Science , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.C.3    Ordlow, I.4    Joseph, C.5    Kolesnick, R.6
  • 49
    • 0027369679 scopus 로고
    • Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin G/H synthase-1 and prostaglandin H synthase-2 isozymes
    • De Witt DL, Meade EA 1993 Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin G/H synthase-1 and prostaglandin H synthase-2 isozymes. Arch Biochem Biophys 306:94-102
    • (1993) Arch Biochem Biophys , vol.306 , pp. 94-102
    • De Witt, D.L.1    Meade, E.A.2
  • 50
    • 0025889011 scopus 로고
    • Characterization of a ceramide activated protein kinase: Stimulation by TNFα
    • Dressler KA, Mathias S, Kolesnick RN 1991 Characterization of a ceramide activated protein kinase: stimulation by TNFα. Proc Natl Acad Sci USA 88:10009-10013
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10009-10013
    • Dressler, K.A.1    Mathias, S.2    Kolesnick, R.N.3
  • 51
    • 0026723048 scopus 로고
    • Ceramide stimulates a cytosolic protein phosphatase
    • Dobrowski RT, Hannun YU 1992 Ceramide stimulates a cytosolic protein phosphatase. J Biol Chem 267:5048-5051
    • (1992) J Biol Chem , vol.267 , pp. 5048-5051
    • Dobrowski, R.T.1    Hannun, Y.U.2
  • 53
    • 0025604502 scopus 로고
    • Follicle-stimulating hormone evokes an increase in intracellular free calcium ion concentrations in single ovarian granulosa cells
    • Flores JA, Veldhuiss JD, Leong DA 1990 Follicle-stimulating hormone evokes an increase in intracellular free calcium ion concentrations in single ovarian granulosa cells. Endocrinology 127:3172-3179
    • (1990) Endocrinology , vol.127 , pp. 3172-3179
    • Flores, J.A.1    Veldhuiss, J.D.2    Leong, D.A.3
  • 54
    • 0027500037 scopus 로고
    • Tyrphostins inhibit follicle-stimulating hormone-mediated functions in cultured rat ovarian granulosa cells
    • Gomberg-Malool Ziv R, Re'em Y, Posner I, Levitzki A, Orly J 1993 Tyrphostins inhibit follicle-stimulating hormone-mediated functions in cultured rat ovarian granulosa cells. Endocrinology 132: 362-370
    • (1993) Endocrinology , vol.132 , pp. 362-370
    • Gomberg-Malool Ziv, R.1    Re'em, Y.2    Posner, I.3    Levitzki, A.4    Orly, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.