Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. II. Structure elucidation and total synthesis

Journal of Antibiotics

Volumn 49, Issue 7, 1996, Pages 624-630

  Kogen, Hiroshi ^a   Tago, Keiko ^a   Kaneko, Satoru ^a   Hamano, Kiyoshi ^a   Onodera, Kaori ^a   Haruyama, Hideyuki ^a   Minagawa, Katsuhiro ^a   Kinoshita, Takeshi ^a   Ishikawa, Tomio ^a   Tanimoto, Tatsuo ^a   Tsujita, Yoshio ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SCHIZOSTATIN; SESQUITERPENE DERIVATIVE; SQUALENE SYNTHASE; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHIZOPHYLLUM COMMUNE;

EID: 9344253815     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.624     Document Type: Article

References (21)

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2. Preliminary communication of this work has been published: TANIMOTO, T.; Y. TSUJITA, K. HAMANO, H. HARUYAMA, T. KINOSHITA, T. HOSOYA, S. KANEKO, K. TAGO & H. KOGEN: Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis. Tetrahedron Lett. 36: 6301-6304, 1995
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