Confirmatory in vivo electrodiagnostic and electromyographic studies for neuromuscular junctional blocking action of CLeistanthus collinus leaf extract in rat

Phytotherapy Research

Volumn 10, Issue 3, 1996, Pages 215-219

  Vijayalakshmi, K M ^a   Nanda Kumar, N V ^a   Pagala, M K D ^b  

^a SRI VENKATESWARA UNIVERSITY   (India)

^b MAIMONIDES MEDICAL CENTER   (United States)

Author keywords

Cleistanthus collinus; Compound muscle action potentials; d tubocurarine; Electrodiagnosis; Neostigmine; Neuromuscular blockade; Sciatic nerve anterior tibialis muscle

Indexed keywords

CHOLINERGIC RECEPTOR; CLEISTANTHUS COLLINUS EXTRACT; NEOSTIGMINE; PLANT EXTRACT; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; ELECTRODIAGNOSIS; ELECTROMYOGRAPHY; INTOXICATION; INTRAPERITONEAL DRUG ADMINISTRATION; MUSCLE ACTION POTENTIAL; MUSCLE EXCITATION; NERVE STIMULATION; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR SYNAPSE; NONHUMAN; PLANT LEAF; RAT; SCIATIC NERVE; TIBIALIS ANTERIOR MUSCLE;

EID: 9344251087     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199605)10:3<215::AID-PTR816>3.0.CO;2-N     Document Type: Article

References (26)

1. Anjaneyulu, A. S. R., Atchuta Ramaiah, P., and Ramachandra Row, L. (1977). Crystalline constituents of Euphorbiaceae: Part VI - A new diphyllin glycoside from Cleistanthus collinus. Roxb. Indian J. Chem. 15B, 10-11.
2. Chopra, R. N., Badwar, R. L., and Ghosh, S. (1965). Poisonous Plants of India, Vol. II, pp. 774-775. Indian Council of Agricultural Research, New Delhi.
3. Colquhoun, D. (1980). Competitive block and ion channel as mechanisms of antagonist action on the skeletal muscle endplate. Adv. Psychopharmacol. 21, 67-80.
4. Colquhoun, D. (1981). The kinetics of conductance changes at nicotinic receptors of the muscle endplate and of ganglia. In Drug Receptors and their Effectors, pp. 107-126. Macmillan, London.
5. Colquhoun, D., and Sheridan, R. E. (1980). Kinetic effects of tubocurarine on skeletal muscle at high agonist concentrations. Br. J. Pharmacol. 68, 143-144.
6. Drachmen, D. B., Kao, I., Pestronk, A., and Toyka, K. V. (1976). Myasthenia gravis as a receptor disorder. Ann. NY Acad. Sci. 274, 226-234.
7. Evans, F. J. (1987). In, Naturally Occuring Phorbol Esters, ed. by F. J. Evans, p 313. CRC Press, Boca Raton.
8. Govindachari, T. R., Sathe, S. S., Viswanathan, N., Pai, B. R., and Srinivasan, N. (1969). Chemical constituents of Cleistanthus Collinus. Tetrahedron 25, 2815-2821.
9. Grob, D., Johns, R. J., and Harvey, A. M. (1956). Studies in neuromuscular function. V. Effects of anticholinesterase compound, d-tubocurarine and decamethonium in normal subjects. Bull. Johns Hopkins Hosp. 99, 195-218.
10. Grob, D., and Namba, T. (1976). Characteristics and mechanism of neuromuscular block in Myasthenia Gravis. Ann. NY Acad. Sci. 274, 143-173.
11. Larnbert, E. H., Lindstrom, J. M., and Lennon, V. A. (1976). Endplate potentials in experimental autoimmune Myasthenia Gravis in rats. Ann. NY, Acad. Sci. 274, 300-318.
12. Modi, N. J. (1977). Text Book of Medical Jurisprudence and Toxicology. N. M. Tripathi, Bombay.
13. Nanda Kumar, N. V., Pagala, M. K. D., Namba, T., and Grob, D. (1988). Effect of poisonous leaf extract of Cleistanthus collinus on neuromuscular function: a plant abused for suicidal and homicidal purpose. Arogya-J. Hlth Sci. XIV, 42-51.
14. Nanda Kumar, N. V., Pagala, M. K. D., Venkatachari, S. A. T., Namba, T., and Grob, D. (1989). Effect of Cleistanthus collinus leaf extract on neuromuscular function of the isolated mouse phrenic nerve-diaphragm. Toxicon, XXVII, 1219-1228.
15. Nanda Kumar, N. V., and Vijayalakshmi, K. M. (1996) Experimental myasthenia gravis like neuromuscular impairment with cleisthanthus collinus leaf extract administration in Rat. Phytotherapy Res. 10, 121-126.
16. Nastuk, N. L., and Wolfson, C. H. (1976). Cholinergic receptor desensitization. Ann. NY Acad. Sci. 274, 130-139.
17. Ozdemir, C., and Young, R. R. (1976). The results to be expected from electrical testing in the diagnosis of myasthenia gravis. Ann. NY Acad. Sci. 274, 203-222.
18. Pagala, M. K. D. (1987). An in vitro electromyography chamber to monitor neuromuscular function. J. Electrophysiol. Tech. 14, 197-209.
19. Pagala, M. K. D., Nanda Kumar, N. V., Venkatachari, S. A. T., Ravindran, K., Namba, T., and Grob, D. (1990). Responses of intercostal muscle biopsies from normal subjects and patients with myasthenia gravis. Muscle Nerve 13, 1012-1022.
20. Pagala, M. K. D., Ravindran, K., Azad, D., Amladevi, B., Namba, T., and Grob, D. (1992) Effect of Cocaine on function of rat heart and skeletal muscle. Research Communications Substances Abuse. 13, 273-286.
21. Sanders, D. B., Schleifer, L. S., Eldefrawi, M. E., Korcross, N. L., and Cobb, E. E. (1976). An immunologically induced defect of neuromuscular transmission in rats and rabbits. Ann. NY Acad. Sci. 274, 226-234.
22. Stalberg, E. (1991). Invited review: Electrodiagnostic Assessment and monitoring of motor unit changes in disease. Muscle Nerve 14, 293-303.
23. Standaert, F. G. (1982). Release of transmitter at the neuromuscular junction. Br. J. Anaesth. 54, 131-145.
24. Synder-Mackler, L., and Robinson, A. J. (1989). Electrotherapy and electrophysiological testing. In, Clinical Electrophysiology. Williams & Wilkins, Baltimore.
25. Taylor, P. (1980). Anticholinesterase agents. In, Goodman & Gilman's The Pharmacological Basis of Therapeutics, pp. 100-119, Macmillan, New York.
26. Vijayalakshmi, K. M., Nanda Kumar, N. V., and Pagala, M. K. D. (1994). Isolation of a neuromuscular junctional blocking agent from Cleistanthus collinus plant leaf extract. Phytother. Res. 8, 245-247.