메뉴 건너뛰기




Volumn 16, Issue 2, 1996, Pages 159-170

Monoclonal antibodies to the human TSH receptor: Epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; MONOCLONAL ANTIBODY; THYROTROPIN; THYROTROPIN RECEPTOR;

EID: 9344232767     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0160159     Document Type: Article
Times cited : (68)

References (39)
  • 1
    • 0026739764 scopus 로고
    • Specific antibody to the thyrotropin receptor identifies multiple receptor forms in membranes of cells transfected with wild type receptor complementary deoxyribonucleic acid: Characterization of their relevance to receptor synthesis, processing, structure and function
    • Ban T, Kosugi S & Kohn LD 1992 Specific antibody to the thyrotropin receptor identifies multiple receptor forms in membranes of cells transfected with wild type receptor complementary deoxyribonucleic acid: characterization of their relevance to receptor synthesis, processing, structure and function. Endocrinology 131 815-829.
    • (1992) Endocrinology , vol.131 , pp. 815-829
    • Ban, T.1    Kosugi, S.2    Kohn, L.D.3
  • 2
    • 0026092621 scopus 로고
    • Long term human B cell lines dependent on interleukin-4 and antibody to CD40
    • Banchereau J, Paoli P, Valle A, Garcia E & Rousset F 1991 Long term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 251 70-72.
    • (1991) Science , vol.251 , pp. 70-72
    • Banchereau, J.1    Paoli, P.2    Valle, A.3    Garcia, E.4    Rousset, F.5
  • 3
    • 0028913483 scopus 로고
    • Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: Implications for the establishment of a mouse model for Graves' disease
    • Carayanniotis G, Huang GC, Nicholson LB, Scott T, Allain P, McGregor AM & Banga JP 1995 Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: implications for the establishment of a mouse model for Graves' disease. Clinical and Experimental Immunology 99 294-302.
    • (1995) Clinical and Experimental Immunology , vol.99 , pp. 294-302
    • Carayanniotis, G.1    Huang, G.C.2    Nicholson, L.B.3    Scott, T.4    Allain, P.5    McGregor, A.M.6    Banga, J.P.7
  • 4
    • 0026049254 scopus 로고
    • Autoantibody stimulation of the human thyrotropin receptor: Regulation of adenylate cyclase activity, thyroglobulin and thyroid peroxidase mRNA levels in primary cultures of Graves' thyroid tissue
    • Collison KS, Banga JP, Barnett PS, Huang GC & McGregor AM 1991 Autoantibody stimulation of the human thyrotropin receptor: Regulation of adenylate cyclase activity, thyroglobulin and thyroid peroxidase mRNA levels in primary cultures of Graves' thyroid tissue. Clinical and Experimental Immunology 86 61-65.
    • (1991) Clinical and Experimental Immunology , vol.86 , pp. 61-65
    • Collison, K.S.1    Banga, J.P.2    Barnett, P.S.3    Huang, G.C.4    McGregor, A.M.5
  • 5
    • 0025735519 scopus 로고
    • Monoclonal antiidiotypic antibodies interact with the 93 kilodalton thyrotropin receptor and exhibit heterogenous biological activities
    • Costagliola S, Ruf J, Durand-Gorde M & Carayon P 1991 Monoclonal antiidiotypic antibodies interact with the 93 kilodalton thyrotropin receptor and exhibit heterogenous biological activities. Endocrinology 128 1555-1562.
    • (1991) Endocrinology , vol.128 , pp. 1555-1562
    • Costagliola, S.1    Ruf, J.2    Durand-Gorde, M.3    Carayon, P.4
  • 6
    • 84995846099 scopus 로고
    • Thyrotropin (TSH) interacts with multiple discrete regions of the TSH receptor: Polyclonal rabbit antibodies to one or more of these regions can inhibit TSH binding and function
    • Dallas JS, Desai RK, Cunningham SJ, Morris JC, Seetharamaiah GS, Wagle N, Goldblum RM & Prabhakar BS 1994 Thyrotropin (TSH) interacts with multiple discrete regions of the TSH receptor: polyclonal rabbit antibodies to one or more of these regions can inhibit TSH binding and function. Endocrinology 134 1437-1445.
    • (1994) Endocrinology , vol.134 , pp. 1437-1445
    • Dallas, J.S.1    Desai, R.K.2    Cunningham, S.J.3    Morris, J.C.4    Seetharamaiah, G.S.5    Wagle, N.6    Goldblum, R.M.7    Prabhakar, B.S.8
  • 7
    • 0026536671 scopus 로고
    • Determination of epitope specificities of monoclonal antibodies to thyroid peroxidase using recombinant antigen preparations
    • Ewins DL, Tomlinson RWS, Barnett PS, McGregor AM & Banga JP 1992 Determination of epitope specificities of monoclonal antibodies to thyroid peroxidase using recombinant antigen preparations. Autoimmunology 11 141-149.
    • (1992) Autoimmunology , vol.11 , pp. 141-149
    • Ewins, D.L.1    Tomlinson, R.W.S.2    Barnett, P.S.3    McGregor, A.M.4    Banga, J.P.5
  • 8
    • 0026802536 scopus 로고
    • Cloning and sequencing of a 1.3 kb variant of human thyrotropin receptor mRNA lacking the transmembrane domain
    • Graves PN, Tomer Y & Davies TF 1992 Cloning and sequencing of a 1.3 kb variant of human thyrotropin receptor mRNA lacking the transmembrane domain. Biochemical and Biophysical Research Communications 187 1135-1143
    • (1992) Biochemical and Biophysical Research Communications , vol.187 , pp. 1135-1143
    • Graves, P.N.1    Tomer, Y.2    Davies, T.F.3
  • 9
    • 0028952460 scopus 로고
    • Folding of the recombinant human thyrotropin (TSH) receptor extracellular domain: Identification of folded monomeric and tetrameric complexes that bind TSH receptor autoantibodies
    • Graves PN, Vlase H & Davies TF 1995 Folding of the recombinant human thyrotropin (TSH) receptor extracellular domain: identification of folded monomeric and tetrameric complexes that bind TSH receptor autoantibodies Endocrinology 136 521-527.
    • (1995) Endocrinology , vol.136 , pp. 521-527
    • Graves, P.N.1    Vlase, H.2    Davies, T.F.3
  • 10
    • 0026637086 scopus 로고
    • Thyrotropin receptor antibodies: Advances and importance of detection techniques in thyroid disease
    • Gupta M 1992 Thyrotropin receptor antibodies: advances and importance of detection techniques in thyroid disease. Clinical Biochemistry 25 193-199.
    • (1992) Clinical Biochemistry , vol.25 , pp. 193-199
    • Gupta, M.1
  • 11
    • 0023919011 scopus 로고
    • Monoclonal antibodies to the thyrotropin receptor raised by a antiidiotypic protocol and their relationship to monoclonal autoantibodies from Graves' patients
    • Hill BL & Erlanger BF 1988 Monoclonal antibodies to the thyrotropin receptor raised by a antiidiotypic protocol and their relationship to monoclonal autoantibodies from Graves' patients. Endocrinology 122 2840-2850
    • (1988) Endocrinology , vol.122 , pp. 2840-2850
    • Hill, B.L.1    Erlanger, B.F.2
  • 12
    • 0026509995 scopus 로고
    • Expression of a human thyrotrophin receptor fragment in Escherichia coli and its interaction with autoantibodies from patients with Graves' disease
    • Huang GC, Collison KC, Page MJ, McGregor AM & Banga JP 1992 Expression of a human thyrotrophin receptor fragment in Escherichia coli and its interaction with autoantibodies from patients with Graves' disease. Journal of Molecular Endocrinology 8 137-144.
    • (1992) Journal of Molecular Endocrinology , vol.8 , pp. 137-144
    • Huang, G.C.1    Collison, K.C.2    Page, M.J.3    McGregor, A.M.4    Banga, J.P.5
  • 13
    • 0027416670 scopus 로고
    • The thyrotrophin hormone receptor of Graves' disease: Overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding
    • Huang GC, Page MJ, Xicholson LB, Collison KS, McGregor AM & Banga JP 1993 The thyrotrophin hormone receptor of Graves' disease: overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding. Journal of Molecular Endocrinology 10 127-142
    • (1993) Journal of Molecular Endocrinology , vol.10 , pp. 127-142
    • Huang, G.C.1    Page, M.J.2    Xicholson, L.B.3    Collison, K.S.4    McGregor, A.M.5    Banga, J.P.6
  • 15
    • 0026522437 scopus 로고
    • Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxoedema: These determinants have no homologous sequences on gonadotropin receptors
    • Kosugi S, Ban T, Akamizu T & Kohn LD 1992 Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxoedema: These determinants have no homologous sequences on gonadotropin receptors. Molecular Endocrinology 6 168-180.
    • (1992) Molecular Endocrinology , vol.6 , pp. 168-180
    • Kosugi, S.1    Ban, T.2    Akamizu, T.3    Kohn, L.D.4
  • 16
    • 0027260342 scopus 로고
    • Use of TSH receptor mutants to detect stimulating TSH receptor antibodies in hypothyroid patients with idiopathic myxoedema, who have blocking TSH receptor antibodies
    • Kosugi S, Ban T, Akamizu T, Valente W & Kohn LD 1993 Use of TSH receptor mutants to detect stimulating TSH receptor antibodies in hypothyroid patients with idiopathic myxoedema, who have blocking TSH receptor antibodies. Journal of Clinical Endocrinology and Metabolism 77 19-24.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.77 , pp. 19-24
    • Kosugi, S.1    Ban, T.2    Akamizu, T.3    Valente, W.4    Kohn, L.D.5
  • 19
    • 0025202998 scopus 로고
    • Autoantibodies to the TSH receptor in patients with autoimmune thyroid disease
    • McGregor AM 1990 Autoantibodies to the TSH receptor in patients with autoimmune thyroid disease. Clinical Endocrinology 33 683-685.
    • (1990) Clinical Endocrinology , vol.33 , pp. 683-685
    • McGregor, A.M.1
  • 20
    • 0016335085 scopus 로고
    • Periodate-lysine-paraformaldehyde: A new fixative for immunoelectron microscopy
    • McLean IW & Nakane PK 1974 Periodate-lysine-paraformaldehyde: a new fixative for immunoelectron microscopy. Journal of Histochemistry and Cytochemistry 22 1077-1083.
    • (1974) Journal of Histochemistry and Cytochemistry , vol.22 , pp. 1077-1083
    • McLean, I.W.1    Nakane, P.K.2
  • 21
    • 0026508153 scopus 로고
    • Characterization, of monoclonal antibodies to the human thyrotropin receptor
    • Marion S, Ropars A, Ludgate M, Braun JM & Charreire J 1992 Characterization, of monoclonal antibodies to the human thyrotropin receptor. Endocrinology 130 967-975.
    • (1992) Endocrinology , vol.130 , pp. 967-975
    • Marion, S.1    Ropars, A.2    Ludgate, M.3    Braun, J.M.4    Charreire, J.5
  • 23
    • 84995853534 scopus 로고
    • Immunohistochemical demonstration of thyrotropin (TSH) receptor in normal and diseased human thyroid tissues using monoclonal antibody against recombinant human TSH receptor protein
    • Mizukami Y, Hashimoto T, Nonomura A, Michigishi T, Nakamura S, Noguchi M & Matsukawa S 1994 Immunohistochemical demonstration of thyrotropin (TSH) receptor in normal and diseased human thyroid tissues using monoclonal antibody against recombinant human TSH receptor protein. Journal of Clinical Endocrinology and Metabolism 79 616-619.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.79 , pp. 616-619
    • Mizukami, Y.1    Hashimoto, T.2    Nonomura, A.3    Michigishi, T.4    Nakamura, S.5    Noguchi, M.6    Matsukawa, S.7
  • 25
    • 9344224305 scopus 로고
    • Human IgG monoclonal autoantibodies from Epstein Barr virus transformed B lymphocytes of Graves' disease patients: Specific antibody to thyrotropin receptor as determined by immunoprecipitation analysis and biological activity
    • Toronto, Canada Abstract
    • Morgenthaler XG, Kim MR, Tremble J, Richter W, Huang WC, Scherbaum WA, Gupta M, McGregor AM & Banga JP 1995 Human IgG monoclonal autoantibodies from Epstein Barr virus transformed B lymphocytes of Graves' disease patients: specific antibody to thyrotropin receptor as determined by immunoprecipitation analysis and biological activity. International Thyroid Congress, Toronto, Canada Abstract No. 13, 5-7.
    • (1995) International Thyroid Congress , vol.13 , pp. 5-7
    • Morgenthaler, X.G.1    Kim, M.R.2    Tremble, J.3    Richter, W.4    Huang, W.C.5    Scherbaum, W.A.6    Gupta, M.7    McGregor, A.M.8    Banga, J.P.9
  • 26
    • 0028071359 scopus 로고
    • Identification of epitopes and affinity purification of thyroid stimulating autoantibodies using synthetic human TSH receptor peptides
    • Morris JC, Gibson JL, Haas EJ, Bergen ER, Dallas JS & Prabhakar BS 1994 Identification of epitopes and affinity purification of thyroid stimulating autoantibodies using synthetic human TSH receptor peptides. Autoimmunity 17 287-299.
    • (1994) Autoimmunity , vol.17 , pp. 287-299
    • Morris, J.C.1    Gibson, J.L.2    Haas, E.J.3    Bergen, E.R.4    Dallas, J.S.5    Prabhakar, B.S.6
  • 27
    • 0026568620 scopus 로고
    • The thyrotropin receptor twenty five years after its discovery: New insights following its molecular cloning
    • Nagayama Y & Rapoport B 1992 The thyrotropin receptor twenty five years after its discovery: new insights following its molecular cloning. Molecular Endocrinology 6 145-156.
    • (1992) Molecular Endocrinology , vol.6 , pp. 145-156
    • Nagayama, Y.1    Rapoport, B.2
  • 29
    • 0025831943 scopus 로고
    • Binding domain of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/choriogonadotropin receptors
    • Nagayama Y, Wadsworth HL, Russo D, Chazenbalk GD & Rapoport B 1991 Binding domain of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/choriogonadotropin receptors. Journal of Clinical Investigation 88 336-340.
    • (1991) Journal of Clinical Investigation , vol.88 , pp. 336-340
    • Nagayama, Y.1    Wadsworth, H.L.2    Russo, D.3    Chazenbalk, G.D.4    Rapoport, B.5
  • 30
    • 0028337046 scopus 로고
    • High affinity binding of thyrotropin and thyroid stimulating auto-antibody for the TSH receptor extracellular domain
    • Nagayama Y, Takeshita A, Luo W, Ashizawa K, Tokoyama N & Nagataki S 1994 High affinity binding of thyrotropin and thyroid stimulating auto-antibody for the TSH receptor extracellular domain. Thyroid 4 155-159.
    • (1994) Thyroid , vol.4 , pp. 155-159
    • Nagayama, Y.1    Takeshita, A.2    Luo, W.3    Ashizawa, K.4    Tokoyama, N.5    Nagataki, S.6
  • 33
    • 0026539685 scopus 로고
    • Differing epitope selection of experimentally induced and natural antibodies to a disease specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex (PDC-E2)
    • Rowley MJ, Maeda T, Mackay IR, Loveland BE, McMullen GL, Tribbick G & Bernard CCA 1992 Differing epitope selection of experimentally induced and natural antibodies to a disease specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex (PDC-E2) International Immunology 4 1245-1253.
    • (1992) International Immunology , vol.4 , pp. 1245-1253
    • Rowley, M.J.1    Maeda, T.2    Mackay, I.R.3    Loveland, B.E.4    McMullen, G.L.5    Tribbick, G.6    Bernard, C.C.A.7
  • 34
    • 0028157562 scopus 로고
    • A recombinant extracellular domain of the thyrotropin receptor binds TSH in the absence of membranes
    • Seetharamaiah GS, Kurosky A, Desai RK, Dallas JS & Prabakar BS 1994 A recombinant extracellular domain of the thyrotropin receptor binds TSH in the absence of membranes. Endocrinology 134 549-554
    • (1994) Endocrinology , vol.134 , pp. 549-554
    • Seetharamaiah, G.S.1    Kurosky, A.2    Desai, R.K.3    Dallas, J.S.4    Prabakar, B.S.5
  • 35
    • 0029054865 scopus 로고
    • Generation and characterization of monoclonal antibodies to the human thyrotropin (TSH) receptor: Antibodies can bind to discrete conformational or linear epitopes and block TSH binding
    • Seetharamaiah GS, Wagle NM, Morris JC & Prabhakar BS 1995 Generation and characterization of monoclonal antibodies to the human thyrotropin (TSH) receptor: antibodies can bind to discrete conformational or linear epitopes and block TSH binding. Endocrinology 136 2817-2824.
    • (1995) Endocrinology , vol.136 , pp. 2817-2824
    • Seetharamaiah, G.S.1    Wagle, N.M.2    Morris, J.C.3    Prabhakar, B.S.4
  • 36
    • 0028877877 scopus 로고
    • Human autoantibodies to the thyrotropin receptor: Recognition of linear, folded and glycosylated recombinant extracellular domain
    • Vlase H, Graves PN, Magnusson P & Davies TF 1995a Human autoantibodies to the thyrotropin receptor: recognition of linear, folded and glycosylated recombinant extracellular domain. Journal of Clinical Endocrinology and Metabolism 80 46-53.
    • (1995) Journal of Clinical Endocrinology and Metabolism , vol.80 , pp. 46-53
    • Vlase, H.1    Graves, P.N.2    Magnusson, P.3    Davies, T.F.4
  • 37
    • 0029093756 scopus 로고
    • Defining the major antibody epitopes on the human thyrotropin receptor: Evidence for intramolecular spreading
    • Vlase H, Nakashima M, Graves PN, Tomer Y, Morris JC & Davies TF 1995b Defining the major antibody epitopes on the human thyrotropin receptor: evidence for intramolecular spreading. Endocrinology 136 4415-4423.
    • (1995) Endocrinology , vol.136 , pp. 4415-4423
    • Vlase, H.1    Nakashima, M.2    Graves, P.N.3    Tomer, Y.4    Morris, J.C.5    Davies, T.F.6
  • 38
    • 0028579773 scopus 로고
    • Autoimmune thyroid disease: Further developments in our understanding
    • Weetman AP & McGregor AM 1994 Autoimmune thyroid disease: further developments in our understanding. Endocrine Reviews 15 788-830.
    • (1994) Endocrine Reviews , vol.15 , pp. 788-830
    • Weetman, A.P.1    McGregor, A.M.2
  • 39
    • 0025272153 scopus 로고
    • Transient neonatal hypothyroidism: Characterization of maternal antibodies to the thyrotropin receptor
    • Zakarya M, McKenzie JM & Eidson MS 1990 Transient neonatal hypothyroidism: characterization of maternal antibodies to the thyrotropin receptor. Journal of Clinical Endocrinology and Metabolism 70 1239-1246.
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.70 , pp. 1239-1246
    • Zakarya, M.1    McKenzie, J.M.2    Eidson, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.