Granisetron in the prevention of vomiting induced by conditioning for stem cell transplantation: A prospective randomized study

Bone Marrow Transplantation

Volumn 17, Issue 5, 1996, Pages 679-683

  Okamoto, S ^a,b   Takahashi, S ^b   Tanosaki, R ^a   Sakamaki, H ^c   Onozawa, Y ^c   Oh, H ^d   Miyawaki, S ^e   Kimura, Y ^f   Toyama, K ^f   Ikeda, Y ^a   Asano, S ^b  

^a KEIO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^d CHIBA UNIVERSITY   (Japan)

^e Maebashi North Hospital   (Japan)

^f TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Bone marrow transplantation; Conditioning; Granisetron; Total body irradiation; Vomiting

Indexed keywords

ANTIEMETIC AGENT; BUSULFAN; CYCLOPHOSPHAMIDE; CYTARABINE; DOMPERIDONE; ETOPOSIDE; GRANISETRON; HALOPERIDOL; HYDROXYZINE EMBONATE; LORAZEPAM; METHYLPREDNISOLONE; METOCLOPRAMIDE; PROCHLORPERAZINE;

ACUTE LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; EXTRAPYRAMIDAL SYNDROME; FEMALE; FEVER; HEADACHE; HEART PALPITATION; HUMAN; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PHOTOPHOBIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; STEM CELL TRANSPLANTATION; TACHYCARDIA; VOMITING;

ADOLESCENT; ADULT; ANTIEMETICS; ANTINEOPLASTIC AGENTS; FEMALE; GRANISETRON; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; METOCLOPRAMIDE; MIDDLE AGED; PROSPECTIVE STUDIES; SAFETY; SEROTONIN ANTAGONISTS; TIME FACTORS; TRANSPLANTATION CONDITIONING; VOMITING; WHOLE-BODY IRRADIATION;

EID: 9344231964     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Wiebe VJ, Smith BR, Degregorio MW, Rappeport JM. Pharmacology of agents used in bone marrow transplant conditioning regimens. Crit Rev Oncol Hematol 1992; 13: 241-270.
2. Danjonx EC, Rider WD, Fitzpatrick PJ. The acute radiation syndrome: a memorial to William Michael Court-Brown. Clin Radiol 1979; 30: 581-584.
3. Shorbe B, Hallen C, Skare NG, Underskog I. Betamethazonedixyrazine combination versus high dose metoclopramide as antiemetic treatment in doxorubicin and cisplatin chemotherapy. Radiother Oncol 1989; 15: 161-167.
4. Fetting JH, Grochow LB, Folstein MF et al. The course of nausea and vomiting after high-dose cyclophosphamide. Cancer Treat Rep 1982; 66: 1487-1493.
5. Kris MG, Tyson LB, Gralla RJ et al. Extrapyramidal reactions with high dose metoclopramide. New Engl J Med 1983; 309: 433-434 (letter).
6. Hesketh PJ, Murphy WK, Lester EP et al. GR 38032F (GR-C507175): a novel compound effective in the prevention of acute cisplatin-induced emesis. J Clin Oncol 1989; 7: 700-705.
7. 3 antagonist, versus a standard anti-emetic regimen of chlorpromazine plus dexamethasone in the treatment of cytostatic-induced emesis. Eur J Cancer 1990; 26 (Suppl. 1) S28-S32.
8. Navari RM, Kaplan HG, Gralla RJ et al. Efficacy and safety of granisetron, a selective 5-hydroxytryptamine-3 receptor antagonist, in the prevention of nausea and vomiting induced by high dose cisplatin. J Clin Oncol 1994; 12: 2204-2210.
9. 3 receptor antagonist, for the prevention of radiation induced emesis during total body irradiation. Bone Marrow Transplant 1991; 7: 439-441.
10. Prentice HG, Cunningham S. Gandhi L et al. Granisetron in the prevention of irradiation-induced emesis. Bone Marrow Transplant 1995; 15: 445-448.
11. 3 antagonist. Bone Marrow Transplant 1991; 7: 431-433.
12. Bosi A, Guidi S, Messori A et al. Ondansetron versus chlopromazine for preventing emesis in bone marrow transplant recipients a double-blind randomized study. J Chemother 1993; 5: 191-196.
13. Spitzer TR, Bryson JC, Cirenza E et al. Randomized double-blind, placebo-controlled evaluation of oral ondansetron in the prevention of nausea and vomiting associated with fractionated total-body irradiation. J Clin Oncol 1994; 12: 2432-2438.
14. Tiley C, Powles R, Catalane J et al. Results of a double blind placebo controlled study of ondansetron as an antiemetic during total body irradiation in patients undergoing bone marrow transplantation. Leuk Lymphoma 1992; 7: 317-321.
15. Fox SM, Einhorn LH, Cox E et al. Ondansetron versus ondansetron, dexamethasone, and chlorpromazine in the prevention of nausea and vomiting associated with multiple-day cisplatin chemotherapy. J Clin Oncol 1993; 11: 2391-2395.