The use of corticosteroids in the management of bacterial meningitis in adults

Journal of Antimicrobial Chemotherapy

Volumn 37, Issue 6, 1996, Pages 1051-1061

  Townsend, Gregory C ^a   Michael Scheld, W ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CORTICOSTEROID; DEXAMETHASONE;

ANIMAL MODEL; BACTERIAL MENINGITIS; HUMAN; INFLAMMATION; MORBIDITY; MORTALITY; NONHUMAN; PRACTICE GUIDELINE; PROGNOSIS; REVIEW;

ADRENAL CORTEX HORMONES; ADULT; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; CLINICAL TRIALS; DEXAMETHASONE; HUMANS; MENINGITIS, BACTERIAL;

EID: 9344231930     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.6.1051     Document Type: Review

References (31)

1. Belsey, M. A., Hoffpauir, C. W. & Smith, M. H. D. (1969). Dexamethasone in the treatment of bacterial meningitis: the effect of study design on the interpretation of results. Pediatrics 44, 503-13.
2. Cooperative Study Group. (1963). The effectiveness of hydrocortisone in the management of severe infections. Journal of the American Medical Association 183, 462-5.
3. de Lemos, R. A. & Haggerty, R. J. (1969). Corticosteroids as an adjunct to treatment of bacterial meningitis: a controlled clinical trial. Pediatrics 44, 30-4.
4. Durand, M. L., Calderwood, S. B., Weber, D. J., Miller, S. I., Southwick, F. S., Caviness, V. S. et al. (1993). Acute bacterial meningitis in adults. A review of 493 episodes. New England Journal of Medicine 328, 21-8.
5. Gaillard, J.-L., Abadie, V., Cheron, G., Lacaille, F., Mahut, B., Silly, C. et al. (1994). Concentrations of ceftriaxone in cerebrospinal fluid of children with meningitis receiving dexamethasone therapy. Antimicrobial Agents and Chemotherapy 38, 1209-10.
6. Girgis, N. I., Farid, Z., Mikhail, I. A., Farrag, I., Sultan, Y. & Kilpatrick, M. E. (1989). Dexamethasone treatment for bacterial meningitis in children and adults. Pediatric Infectious Disease Journal 8, 848-51.
7. Kadurugamuwa, J. L., Hengstler, B. & Zak, O. (1989). Cerebrospinal fluid protein profile in experimental pneumococcal meningitis and its alteration by ampicillin and antiinflammatory agents. Journal of Infectious Diseases 159, 26-34.
8. Kanra, G. Y., Özen, H., Sȩmeer, G., Ceyhan, M., Ecevit, Z. & Belgin, E. (1995). Beneficial effects of dexamethasone in children with pneumococcal meningitis. Pediatric Infectious Disease Journal 14, 490-4.
9. Kilpi, T., Peltola, H., Jauhiainen, T., Kallio, M. J. T. & the Finnish Study Group. (1995). Oral glycerol and intravenous dexamethasone in preventing neurologic and audiologic sequelae of childhood bacterial meningitis. Pediatric Infectious Disease Journal 14, 270-8.
10. Klein, J. O., Feigin, R. D. & McCracken, G. H. (1986). Report of the task force on diagnosis and management of meningitis. Pediatrics 78, Part 2. 959-82.
11. Lebel, M. H., Freij, B. J., Syrogiannopoulos, G. A., Chrane, D. F., Hoyt, M. J., Stewart, S. M. et al. (1988). Dexamethasone therapy for bacterial meningitis. Results of two double-blind, placebo-controlled trials. New England and Journal of Medicine 319, 964-71.
12. Lebel, M. H., Hoyt, M. J., Waagner, D. C., Rollins, N. K., Finitzo, T. & McCracken, G. H. (1989). Magnetic resonance imaging and dexamethasone therapy for bacterial meningitis. American Journal of Diseases of Children 143, 301-6.
13. Mustafa, M. M., Ramilo, O., Mertsola, J., Risser, R. C., Beutler, B., Hansen, E. J. et al. (1989). Modulation of inflammation and cachectin activity in relation to treatment of experimental Haemophilus influenzae type b meningitis. Journal of Infectious Diseases 160, 818-25.
14. Nolan, C. M., McAllister, C. K., Walters, E. & Beaty, H. N. (1978). Experimental pneumococcal meningitis. IV. The effect of methylprednisolone on meningeal inflammation. Journal of Laboratory and Clinical Medicine 91, 979-88.
15. Odio, C. M., Faingezicht, I., Paris, M., Nassar, M., Baltodano, A., Rogers, J. et al. (1991). The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis. New England Journal of Medicine 324, 1525-31.
16. Paris, M. M., Hickey, S. M., Uscher, M. I., Shelton, S., Olsen, K. D. & McCracken, G. H. (1994). Effect of dexamethasone on therapy of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis. Antimicrobial Agents and Chemotherapy 38, 1320-4.
17. Pomeroy, S. L., Holmes, S. J., Dodge, P. R. & Feigin, R. D. (1990). Seizures and other neurologic sequelae of bacterial meningitis in children. New England Journal of Medicine 323, 1651-7.
18. Quagliarello, V. & Scheld, W. M. (1992). Bacterial meningitis: pathogenesis, pathophysiology, and progress. New England Journal of Medicine 327, 864-72.
19. Rodriguez, A. F., Kaplan, S. L., Hawkins, E. P. & Mason, E. O. (1991). Effect of dexamethasone or HWA-138 in combination with antibiotics in experimental Haemophilus influenzae type b infection. Antimicrobial Agents and Chemotherapy 35, 1980-4.
20. Sáez-Llorens, X., Ramilo, O., Mustafa, M. M., Mertsola, J. & McCracken, G. H. (1990). Molecular pathophysiology of bacterial meningitis: current concepts and therapeutic implications. Journal of Pediatrics 116, 671-84.
21. Schaad, U. B., Lips, U., Gnehm, H. E., Blumberg, A., Heinzer, I. & Wedgewood, J. (1993). Dexamethasone therapy for bacterial meningitis in children. Lancet 342, 457-61.
22. Schaad, U. B., Suter, S., Gianella-Borradori, A., Pfenninger, J., Auckenthaler, R., Bernath, O. et al. (1990). A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children. New England Journal of Medicine 322, 141-7.
23. Scheld, W. M. & Brodeur, J. (1983). Effect of methylprednisolone on entry of ampicillin and gentamicin into cerebrospinal fluid in experimental pneumococcal and Escherichia coli meningitis. Antimicrobial Agents and Chemotherapy 23, 108-12.
24. Scheld, W. M., Dacey, R. G., Winn, H. R., Welsh, J. E., Jane, J. A. & Sande, M. A. (1980). Cerebrospinal fluid outflow resistance in rabbits with experimental meningitis. Alterations with penicillin and methylprednisolone. Journal of Clinical Investigation 66, 243-53.
25. Schlech, W. F., Ward, J. I., Band, J. D., Hightower, A. W., Fraser, D. W. & Broome, C. V. (1985). Bacterial meningitis in the United States, 1978 through 1981. The National Bacterial Meningitis Surveillance Study. Journal of the American Medical Association 253, 1749-54.
26. Sell, S. H. (1983). Long term sequelae of bacterial meningitis in children. Pediatric Infectious Disease Journal 2, 90-3.
27. Syrogiannopoulos, G. A., Lourida, A. N., Theodoridou, M. C., Pappas, I. G., Babilis, G. C., Economidis, J. J. et al. (1994). Dexamethasone therapy for bacterial meningitis in children: 2- versus 4-day regimen. Journal of Infectious Diseases 169, 853-8.
28. Täuber, M. G., Khayam-Bashi, H. & Sande, M. A. (1985). Effects of ampicillin and corticosteroids on brain water content, cerebrospinal fluid pressure, and cerebrospinal fluid lactate levels in experimental pneumococcal meningitis. Journal of Infectious Diseases 151, 528-34.
29. Tunkel, A. R., Wispelwey, B. & Scheld, W. M. (1990). Bacterial meningitis: recent advances in pathophysiology and treatment. Annals of International Medicine 112, 610-23.
30. Waagner, D. C., Kennedy, W., Hoyt, M. J. & McCracken, G. H. (1990). Lack of adverse effects of dexamethasone therapy in aseptic meningitis. Pediatric Infectious Disease Journal 9, 922-3.
31. Wenger, J. D., Hightower, A. W., Facklam, R. R., Gaventa, S., Broome, C. V. & the Bacterial Meningitis Study Group. (1990). Bacterial meningitis in the United States, 1986: report of a multistate surveillance study. Journal of Infectious Diseases 162, 1316-23.