Synthesis of 4′-methyl and 4′-cyano carbocyclic 2′,3′-didehydro nucleoside analogues via 1,4-addition to substituted cyclopentenones

Journal of Organic Chemistry

Volumn 69, Issue 24, 2004, Pages 8492-8495

  Hegedus, Louis S ^a   Cross, Jeff ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATES; CATALYSIS; KETONES; MIXTURES; PALLADIUM; REACTION KINETICS; STEREOCHEMISTRY; SUBSTITUTION REACTIONS;

ALLYLIC SUBSTITUTION REACTIONS; CARBOCYCLIC COMPOUNDS; EPIMERIZATION; MICHAEL REACTION; NUCLEOSIDES;

SYNTHESIS (CHEMICAL);

4' CYANOCARBOCYCLIC 2',3' DIDEHYDRONUCLEOSIDE; 4' METHYLCARBOCYCLIC 2',3' DIDEHYDRONUCLEOSIDE; CYCLOPENTANONE DERIVATIVE; NUCLEOSIDE ANALOG; UNCLASSIFIED DRUG; CYCLOPENTANE DERIVATIVE; CYCLOPENTENONE; NUCLEOSIDE;

ALKYLATION; ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; ELECTRON TRANSPORT; METHYLATION; PROTON TRANSPORT; STEREOISOMERISM; X RAY DIFFRACTION; CHEMISTRY; CONFORMATION; CYCLIZATION; SYNTHESIS;

CYCLIZATION; CYCLOPENTANES; MOLECULAR CONFORMATION; NUCLEOSIDES; STEREOISOMERISM;

EID: 9344228494     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo040215h     Document Type: Article

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