A controlled trial of deprenyl in children with Tourette's syndrome and attention deficit hyperactivity disorder

Neurology

Volumn 46, Issue 4, 1996, Pages 965-968

  Feigin, A ^a,c   Kurlan, R ^a   McDermott, M P ^a   Beach, J ^b   Dimitsopulos, T ^a   Brower, C A ^a   Chapieski, L ^b   Trinidad, K ^a   Como, P ^a   Jankovic, J ^b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SELEGILINE;

ADOLESCENT; AGITATION; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DISEASE ASSOCIATION; DISEASE SEVERITY; DROWSINESS; DRUG EFFECT; DRUG EFFICACY; FEMALE; GILLES DE LA TOURETTE SYNDROME; HEADACHE; HUMAN; IRRITABILITY; MALE; MINIMAL BRAIN DYSFUNCTION; NAUSEA; PRIORITY JOURNAL; RASH; TIC; TREATMENT OUTCOME;

EID: 9244264394     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.46.4.965     Document Type: Article

References (28)

1. Jankovic J. The neurology of tics. In: Marsden CD, Fahn S, eds. Movement disorders 2. London: Butterworths Scientific, 1987:383-405.
2. Kurlan R. Tourette's syndrome: current concepts. Neurology 1989;39:1625-1630.
3. Singer HS, Rosenberg LA. Development of behavioral and emotional problems in Tourette's syndrome. Pediatr Neurol 1989;5:41-44.
4. Jacobvitz D, Sroufe A, Stewart M, Leffert N. Treatment of attentional and hyperactivity problems in children with sympathomimetic drugs: a comprehensive review. J Am Acad Child Adolesc Psychiatry 1990;29:677-688.
5. Grad L, Pelcovitz D, Olson M, et al. Obsessive-compulsive symptomatology in children with Tourette's syndrome. J Am Acad Child Adolesc Psychiatry 1987;26:69-73.
6. Jankovic J, Rohaidy H. Motor, behavioral and pharmacologic findings in Tourette's syndrome. Can J Neurol Sci 1987;14: 541-546.
7. Comings DE, Himes JA, Comings BG. An epidemiologic study of Tourette's syndrome in a single school district. J Clin Psychiatry 1990;51:463-469.
8. Comings DE, Comings BG. Tourette syndrome: clinical and psychological aspects of 250 cases. Am J Hum Genet 1985; 37:435-450.
9. Stevenson RD, Wolraich MI. Stimulant medication therapy in the treatment of children with attention deficit hyperactivity disorder. Clin Pharmacol 1989;36:1183-1195.
10. Gadow KD, Sverd J. Stimulants for ADHD in child patients with Tourette's syndrome: the issue of relative risk. J Dev Behav Pediatr 1990;11:269-271.
11. Robertson MM, Eapen V. Pharmacologic controversy of CNS stimulants in Gilles de la Tourette's syndrome. Clin Neuropharmacol 1992;15:408-425.
12. Jankovic J, Glaze DG, Frost JD. Effect of tetrabenazine on tics and sleep of Gilles de la Tourette's syndrome. Neurology 1984;34:688-692.
13. Singer HS, Butler IJ, Tune LE, et al. Dopaminergic dysfunction in Tourette syndrome. Arch Neurol 1982;12:361-366.
14. Klawans H, Falk DK, Nausieda PA, Weiner WJ. Gilles de la Tourette's syndrome after long-term chlorpromazine therapy. Neurology 1978;28:1064-1068.
15. Stern GM, Lees AJ, Hardie R, Sandler M. Clinical and pharmacological aspects of (-)deprenyl treatment in Parkinson's disease. Mob Probl Pharmacopsychiat 1993;19:215-219.
16. Jankovic J. Deprenyl in attention deficit associated with Tourette's syndrome. Arch Neurol 1993;50:286-288.
17. DuPauls GS. Parent and teacher ratings of ADHD symptoms: psychometric properties in a community based sample. J Clin Child Psychol 1991;20:243-253.
18. Achenbach TM, Edelbrock CS. Manual for the Child Behavioral Checklist and revised behavioral profile. Burlington, VT: University of Vermont Department of Psychiatry, 1983.
19. Berg CJ, Rapaport JL, Flament MF. The Leyton obsessional inventory - child version. J Am Acad Child Psychiatry 1986; 25:84-92.
20. Goodwin WK, Price LM, Rasmussen SA, et al. The Yale-Brown obsessive compulsive scale. I. development, use, and reliability. Arch Gen Psychiatry 1981;46:1006-1011.
21. Leckman JF, Towbin KE, Ort SI, et al. The Yale global tic severity scale (YGTSS): initial testing of a clinician-rated scale of tic severity. J Am Acad Child Adolesc Psychiatry 1989;28:566-573.
22. Goetz CG, Tanner CM, Wilson RS, et al. A rating scale for Gilles de la Tourette's syndrome: description, reliability, and validity data. Neurology 1987;37:1542-1544.
23. Jones B, Kenward MG. Design and analysis of cross-over trials. London: Chapman and Hall, 1989.
24. Senn S. Cross-over trials in clinical research. New York: Wiley, 1993.
25. Physicians' desk reference, 49th ed. Montvale, NJ: Medical Economics Data Production Company, 1995:419, 2362.
26. Heinonen EH, Antilla MI, Lammintausta RAS. Pharmacokinetic aspects of l-deprenyl (selegiline) and its metabolites. Clin Pharm Ther 1994;56:742-749.
27. Zametkin A, Rapaport JL, Murphy DL, et al. Treatment of hyperactive children with monoamine oxidase inhibitors. I. clinical efficacy. Arch Gen Psychiatr 1985;42:962-966.
28. Elia J. Use of moclobemide in children with attention deficit hyperactivity disorder. Psychopharmacology 1992;106(Suppl): S134-136.