Cerebrospinal fluid leakage: Agarose gel electrophoresis detection of β2-transferrin and nephelometric quantification of β-trace protein

Clinical Chemistry

Volumn 50, Issue 12, 2004, Pages 2401-2403

  Sanders, Elizabeth L ^a   Clark, Raynell J ^a   Katzmann, Jerry A ^a,b  

^a Mayo Clinic   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 TRANSFERRIN; BETA TRACE PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; AUTOMATION; CONTROLLED STUDY; DILUTION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; LABORATORY DIAGNOSIS; LIQUORRHEA; NEPHELOMETRY; PROTEIN DETERMINATION; QUANTITATIVE DIAGNOSIS; SENSITIVITY ANALYSIS;

ELECTROPHORESIS, AGAR GEL; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; NEPHELOMETRY AND TURBIDIMETRY; SUBDURAL EFFUSION; TRANSFERRIN;

EID: 9244262498     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.040246     Document Type: Article

References (9)

1. Meurman OH, Irjala K, Suonpaa J, Laurent B. A new method for the identification of cerebrospinal fluid leakage. Acta Otolaryngol 1979;87:366-9.
2. Oberascher G. Cerebrospinal otorrhea-cerebrospinal rhinorrhea. The Salzburg concept of cerebrospinal fluid diagnosis. Laryngol Rhinol Otol (Stuttg) 1988;67:375-81.
3. Reisinger PW, Hochstrasser K. The diagnosis of CSF fistulae on the basis of detection of β2-transferrin by polyacrylamide gel electrophoresis and immunoblotting. J Clin Chem Clin Biochem 1989;27:169-72.
4. Normansell DE, Stacy EK, Booker CF, Butler TZ. Detection of β-2 transferrin in otorrhea and rhinorrhea in a routine clinical laboratory setting. Clin Diagn Lab Immunol 1994;1:68-70.
5. Hoffmann A, Conradt HS, Gross G, Nimtz M, Lottspeich F, Wurster U. Purification and chemical characterization of β-trace protein from human cerebrospinal fluid: its identification as prostaglandin D synthase. J Neurochem 1993;61:2:451-6.
6. Arrer E, Meco C, Oberascher G, Piotrowski W, Albegger K. β-Trace protein as a marker for cerebrospinal fluid rhinorrhea. Clin Chem 2002;48:939-41.
7. Donadio C, Lucchesi A, Ardini M, Donadio E, Giordani R. Serum levels of β-trace protein and glomerular filtration rate-preliminary results. J Pharm Biomed Anal 2003;1099-104.
8. Reiber H, Walther K, Althaus H. Beta-trace protein as sensitive marker for CSF rhinorhea and CSF otorhea. Acta Neurol Scand 2003;108:359-62.
9. Bachmann G, Petereit H, Djenabi U, Michel O. Predictive values of β-trace protein (prostaglandin D synthase) by use of laser-nephelometry assay for the identification of cerebrospinal fluid. Neurosurgery 2002;50:571-7.