Effect of the eradication of Helicobacter pylori on duodenal ulcer healing and ulcer relapse: Randomized controlled study in Japan

Journal of Gastroenterology

Volumn 31, Issue 2, 1996, Pages 175-181

  Shirotani, Takuro ^a   Okada, Mitsuo ^a   Murayama, Hiroshi ^a   Maeda, Kazuhiro ^a   Seo, Mitsuru ^a   Okabe, Nobuo ^a   Nakahara, Tsukane ^a   Oh, Kohji ^a   Nakayama, Yoshifuku ^a   Hoshiko, Kiyomi ^a   Oda, Kazuto ^a   Okumura, Makoto ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Duodenal ulcer; Eradication; Gastritis; H. pylori; Relapse

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; ANTIULCER AGENT; CIMETIDINE; METRONIDAZOLE; TEPRENONE;

ACID SECRETION; ADULT; ANTIMICROBIAL THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DUODENUM ULCER; FEMALE; GASTRITIS; GLOSSITIS; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; JAPAN; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENCE RISK; RELAPSE; SCAR FORMATION; ULCER HEALING;

ADULT; AMOXICILLIN; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; CIMETIDINE; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; DUODENAL ULCER; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; METRONIDAZOLE; MIDDLE AGED; PENICILLINS; PROGNOSIS; RECURRENCE; TREATMENT OUTCOME; WOUND HEALING;

EID: 9244243164     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02389515     Document Type: Article

References (33)

1. Marshall BJ, Goodwin CS, Warren JR, et al. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet 1988;II:1437-1442.
2. Coghlan JG, Gilligan D, Humphries H, et al. Campylobacter pylori and recurrence of duodenal ulcers - A 12-month follow-up study. Lancet 1987;11:1109-1111.
3. Graham DY, Lew GM, Klein PD, et al. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med 1992;116:705-708.
4. Unge P, Gad A, Eriksson K, et al. Amoxicillin added to omeprazole prevents relapse in the treatment of duodenal ulcer patients. Eur J Gastroenterol Hepatol 1993;5:325 331.
5. Massarrat S, Dehbashi N, Salari S, et al. Comparison of two treatment regimens (4 weeks ranitidine versus 2 weeks bismuth and tetracycline followed by 2 weeks metronidazole) for acute duodenal ulcer and ulcer relapse. Eur J Gastroenterol Hepatol 1992;4:877-880.
6. Mannes GA, Bayerdörffer E, Höchter W, et al. Decreased relapse rate after antibacterial treatment of Helicobacter pylori-associated duodenal ulcers. Munich duodenal ulcer trial. Eur J Gastroenterol Hepatol 1993;5:145-153.
7. Hentschel E, Brandstätter G, Dragosics B, et al. Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. N Engl J Med 1993;328:308-312.
8. Rauws EAJ, Tytgat GNJ. Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet 1990;335:1233-1235.
9. Graham DY, Lew GM, Evans DG, et al. Effect of triple therapy (antibiotics plus bismuth) on duodenal ulcer healing. A randomized controlled trial. Ann Intern Med 1991;115:266-269.
10. Kohli Y, Kato T, Ito S, et al. Significance of Helicobacter pylori infection in human peptic ulcers. Dig Endosc 1993;5:43-48.
11. Uemura N, Okamoto S, Mukai T, et al. The role of eradication of Helicobacter pylori in healing and recurrence of peptic ulcer. In: Proc of the 7th international symposium on Helicobacter pylori and its disease. April 18-19, 1994, Tokyo, Abstracts p28.
12. Sakita T, Fukutomi T. Endoscopic diagnosis (in Japanese). In: Yoshitosi Y (ed) Ulcers of stomach and duodenum. Tokyo: Nankodo 1971;197-208.
13. Miyake T, Suzuki T, Oishi M. Correlation of gastric ulcer healing features of endoscopy, stereoscopic microscopy, and histology, and a reclassification of the epithelial regenerative process. Dig Dis Sci 1980;25:8-14.
14. Paoluzi P, Ricotta G, Ripoli F, et al. Incompletely and completely healed duodenal ulcers' outcome in maintenance treatment: A double blind controlled study. Gut 1985;26:1080-1085.
15. Okada M, Yao T, Maeda K, et al. Predictors of duodenal ulcer healing during treatment with cimetidine. Gut 1990;31:758-762.
16. Terano A, Shiga J, Hiraishi H, et al. Protective action of tetraprenylacetone against ethanol-induced damage in rat gastric mucosa. Digestion 1986;35:182-188.
17. Arakawa T, Yamada H, Nakamura A, et al. Gastric cytoprotection by tetraprenylacetone in human subjects. Digestion 1988, 39:111-117.
18. Narikawa S, Yanagawa A, Hori S, et al. Effect of anti-ulcer terpenes and some antimicrobial agents on the growth of Helicobacter pylori (in Japanese). Jpn J Inflammation 1992;12:343-347.
19. Fukami T: Isolation, identification of Campylobacter pylori (in Japanese). Examination and Technology 1989;17:1389-1394.
20. Spinzi GC, Sangioranni A, Imperiali G, et al. Prevention of duodenal ulcer relapse with amoxicillin and omeprazole. Eur J Gastroenterol Hepathol 1994;6:599-602.
21. Marshall BJ, Armstrong JA, Francis GJ, et al. Antibacterial action of bismuth in relation to Campylobacter pyloridis colonization and gastritis. Digestion 1987;37[Suppl 2]:16-30.
22. Rugge M, Mario FDI, Cassaro M, et al. Pathology of the gastric antrum and body associated with Helicobacter pylori infection in non-ulcerous patients: Is the bacterium a promoter of intestinal metaplasia? Histopathology 1993;22:9-15.
23. Hosking SW, Ling TKW, Chung SCS, et al. Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: Randomised controlled trial. Lancet 1994;343:508-510.
24. Bayerdörffer E, Mannes GA, Sommer A, et al. High-dose omeprazole treatment combined with amoxicillin eradicates Helicobacter pylori. Eur J Gastroenterol Hepatol 1992;4:697-702.
25. Boixeda D, Rafael LD, Cantón R, et al. Galenical formulations of amoxicillin/clavulanate and eradication of Helicobacter pylori in peptic ulcer patients: Preliminary report. Eur J Gastroenterol Hepatol 1993;5:283-285.
26. Chiba N, Rao BV, Rademaker JW, et al. Meta-analysis of the efficacy of antibiotic therapy in eradicating Helicobacter pylori. Am J Gastroenterol 1992;87:1716-1727.
27. Rauws EAJ, Langenberg W, Houthoff HJ, et al. Campylobacter pyloridis-associated chronic active antral gastritis. A prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology 1988;94:33-40.
28. Stolte M, Eidt S, Ohnsmann A. Differences in Helicobacter pylori- associated gastritis in the antrum and body of the stomach. Z Gastroenterol 1990;28:229-233.
29. Louw JA, Falck V, Rensbesg CV, et al. Distribution of Helicobacter pylori colonization and associated gastric inflammatory change: Difference between patients with duodenal and gastric ulcers. J Clin Pathol 1993;46:754-756.
30. Tytgat GNJ, Dixon MF. Helicobacter pylori infection: Role in peptic ulcer disease. In: Northfield TC, Memdal M, Goggin PM (eds) Helicobacter pylori infection - Pathophysiology, epidemiology and management. London: Kluwer Academic, 1993;75-87.
31. Nishimaki T, Watanabe H, Muto T. Histological findings on the clinically healing state of gastric ulcers (in Japanese with English abstract). Stomach Intest 1984;19:993-999.
32. Miyake T, Ariyoshi J, Suzaki T, et al. Endoscopic evaluation of the effects of sucralfate therapy and other clinical parameters on the recurrence rate of gastric ulcers Dig Dis Sci 1980;25:1-7.
33. Takemoto T, Namiki M, Ishikawa M, et al. Ranitidine and sucralfate as maintenance therapy for gastric ulcer disease: Endoscopic control and assessment of scarring. Gut 1989;30: 1692-1697.