Characterization of peripheral blood progenitor cells (PBPC) mobilized by filgrastim (rHuG-CSF) in normal volunteers: Dose-effect relationship for filgrastim with the character of mobilized PBPC

British Journal of Haematology

Volumn 92, Issue 4, 1996, Pages 795-803

  Tanaka, Ryuhei ^a   Matsudaira, Tadahiro ^b   Aizawa, Jun ^b   Ebihara, Yasuhiro ^a   Muraoka, Kenji ^a   Tsuji, Kohichiro ^a   Ikebuchi, Kenji ^a   Kodama, Kazuo ^c   Takaku, Fumimaro ^d   Nakahata, Tatsutoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Amgen Limited   (Japan)

^c KITASATO INSTITUTE   (Japan)

^d NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

CD34+ cell; colony forming cell; filgrastim; normal volunteer; PBPC

Indexed keywords

CD34 ANTIGEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ARTICLE; COLONY FORMING CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 9244241534     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.412949.x     Document Type: Article

References (27)

1. Andrews, R.G., Singer, J.W. & Bernstein, I.D. (1989) Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties. Journal of Experimental Medicine, 169, 1721-1731.
2. Bensinger, W.I., Weaver, C.H., Appelbaum, F.R., Rowley, S., Demirer, T., Sanders, J., Storb, R. & Buckner, C.D. (1995) Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colony-stimulating factor. Blood, 85, 1655-1658.
3. Bishop, M.R., Anderson, J.R., Jackson, J.D., Bierman, P.J., Reed, E.C., Vose, J.M., Armitage, J.O., Warkentin, P.I. & Kessinger, A. (1994) High-dose therapy and peripheral blood progenitor cell transplantation: effects of recombinant human granulocyte-macrophage colony-stimulating factor on the autograft. Blood, 83, 610-616.
4. Chao, N.J., Schriber, J.R., Grimes, K., Long, G.D., Negrin, R.S., Raimondi, C.M., Horning, S.J., Brown, S.L., Miller, L. & Blume, K.G. (1993) Granulocyte colony-stimulating factor 'mobilized' peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy. Blood, 81, 2031-2035.
5. De Revel, T., Appelbaum, F.R., Storb, R., Schuening, F., Nash, R., Deeg, J., McNiece, I., Andrews, R. & Graham, T. (1994) Effects of granulocyte colony-stimulating factor and stem cell factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs. Blood, 83, 3795-3799.
6. Dreger, P., Haferlach, T., Eckstein, V., Jacobs, S., Suttorp, M., Löffler, H., M-Ruchholtz, W. & Schmitz, N. (1994) G-CSF-mobilized peripheral blood progenitor cells for allogeneic transplantation: safety, kinetics of mobilization, and composition of the graft. British Journal of Haematoloay, 87, 609-613.
7. Dührsen, U., Villeval, J.L., Boyd, J., Kannourakis, G., Morstyn, G. & Metcalf, D. (1988) Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients. Blood, 72, 2074-2081.
8. Gabrilove, J.L., Jakubowski, A., Fain, K., Grous, J., Scher ,H., Stenberg, C., Yagoda, A., Clarkson, B., Bonilla, M.A., Oettgen, H.F., Alton, K., Boone, T., Altrock, B., Weite, K. & Souza, L. (1988) Phase I study of granulocyte colony-stimulating factor in patients with transitional cell carcinoma of the urothelium. Journal of Clinical Investigation. 82, 1454-1461.
9. Imai, T., Koike, K., Kubo, T., Kikuchi, T., Amano, Y., Takagi, M., Okumura, N. & Nakahata, T. (1991) Interleukin-6 supports human megakaryocytic proliferation and differentiation in vitro. Blood. 78, 1969-1974.
10. Janssen, W.E. (1993) Peripheral blood and bone marrow hematopoietic stem cells: Are they the same? Seminars in Oncology, 20, 19-27.
11. Körbling, M., Przepiorka, D., Huh, Y.O., Engel, H., Van Besien, K., Giralt, S., Andersson, B., Kleine, H.D., Seong, D., Deisseroth, A.B., Andreeff, M. & Champlin, R. (1995) Allogeneic blood stem cell transplantation for refractory leukemia and lymphoma: potential advantage of blood over marrow allografts. Blood, 85, 1659-1665.
12. Lane, T.A., Law, P., Maruyama, M., Young, D., Burgess, J., Müllen, M., Mealiffe, M., Terstappen, L.W.M.M., Hardwick, A., Moubayed, M., Oldham, F., Corringham, R.E.T. & Ho, A.D. (1995) Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: potential role in allogeneic marrow transplantation. Blood, 85, 275-282.
13. Nakahata, T. & Ogawa, M. (1982) Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies. Proceedings of the National Academy of Sciences of the United States of America, 79, 3843-3847.
14. Nakahata, T., Tsuji, K., Ishiguro, A., Ando, O., Norose, N., Koike, K. & Akabane, T. (1985) Single-cell origin of human mixed hemopoietic colonies expressing various combinations of cell lineages. Blood, 65, 1010-1016.
15. Nishi, N., Nakahata, T., Koike, K., Takagi, M., Naganuma, K. & Akabane, T. (1990) Induction of mixed erythroid-megakaryocyte colonies and bipotential blast cell colonies by recombinant human erythropoietin In serum-free culture. Blood, 76, 1330-1335.
16. Richman, C.M., Weiner, R.S. & Yankee, R.A. (1976) Increase in circulating stem cells following chemotherapy in man. Blood, 47, 1031-1039.
17. Russell, N.H., Hunter, A., Rogers, S., Hanley, J. & Anderson, D. (1993) Peripheral blood stem cells as an alternative to marrow for allogeneic transplantation. Lancet, 341, 1482.
18. Schmitz, N., Dreger, P., Suttorp, M., Rohwedder, E.B., Haferlach, T., Löffler, H., Hunter, A. & Russell, N.H. (1995) Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor). Blood, 85, 1666-1672.
19. Sheridan, W.P., Begley, C.G., Juttner, C.A., Szer, J., To, L.B., Mäher, D., McGrath, K.M., Morstyn, G. & Fox, R.M. (1992) Effect of peripheral-blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet, 339, 640-644.
20. Sun, T.(1993) Color Atlas/Text of Flow Cytometric Analysis of Hematologic Neoplasms. Igaku-Shoin Medical Publishers, Tokyo.
21. Tanaka, R., Koike, K., Imai, T., Shiohara, M., Kubo, T., Amano, Y., Komiyama, A. & Nakahata, T. (1992) Stem cell factor enhances proliferation, but not maturation, of murine megakaryocytic progenitors in serum-free culture. Blood, 80, 1743-1749.
22. - progenitor cells. Blood, 77, 1218-1227.
23. + peripheral blood cells from healthy adults mobilized by recombinant human granulocyte colony-stimulating factor. Blood, 84, 2795-2801.
24. + cells. Blood, 84, 2930-2939.
25. To, L.B., Haylock, N., Kimber, R.J. & Juttner, C.A. (1984) High levels of circulating haemopoietic stem cells in very early remission from acute non-lymphoblastic leukaemia and their collection and cryopreservation. British Journal of Haematology, 58, 399-410.
26. Verfaillie, C., Blakolmer, K. & McGlave, P. (1990) Purified primitive human hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma. Journal of Experimental Medicine, 172, 509-520.
27. Yan, X-Q., Briddell, R., Hartley, C., Stoney, G., Samal, B. & McNiece, I. (1994) Mobilization of long-term hematopoietic reconstituting cells in mice by the combination of stem cell factor plus granulocyte colony-stimulating factor. Blood, 84, 735-799.