New medication strategies for comorbid substance use and bipolar affective disorders

Biological Psychiatry

Volumn 56, Issue 10, 2004, Pages 771-777

  Kosten, Thomas R ^a   Kosten, Therese A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Affective disorders; attention deficit hyperactivity disorder; bipolar disorder; bupropion; pemoline; valproate

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BACLOFEN; BENZODIAZEPINE; BUPRENORPHINE; CLOZAPINE; COCAINE; DEXAMPHETAMINE; FLUOXETINE; GABAPENTIN; LAMOTRIGINE; LITHIUM; LOFEXIDINE; METHADONE; NALTREXONE; NEUROLEPTIC AGENT; OLANZAPINE; PAROXETINE; PEMOLINE; PSYCHOSTIMULANT AGENT; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; STABILIZING AGENT; TIAGABINE; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROATE SEMISODIUM; VALPROIC ACID; VENLAFAXINE; VIGABATRIN;

AGITATION; AKATHISIA; ALCOHOLISM; ATTENTION DEFICIT DISORDER; BIPOLAR DISORDER; BIPOLAR MANIA; CLINICAL TRIAL; COCAINE DEPENDENCE; COMORBIDITY; DOPAMINERGIC TRANSMISSION; DRUG DEPENDENCE; DRUG EFFICACY; DRUG TOLERANCE; HUMAN; LIVER TOXICITY; MEDICAL INFORMATION; MEDICAL LIABILITY; MESOLIMBIC DOPAMINERGIC SYSTEM; NEUROBIOLOGY; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; PSYCHOSIS; RELAPSE; REVIEW; SCHIZOPHRENIA; SEROTONINERGIC SYSTEM; SIDE EFFECT; SUBSTANCE ABUSE; SUICIDAL BEHAVIOR; WITHDRAWAL SYNDROME;

ADOLESCENT; ADULT; BIPOLAR DISORDER; COMORBIDITY; DEPRESSIVE DISORDER; HUMANS; REINFORCEMENT (PSYCHOLOGY); SUBSTANCE-RELATED DISORDERS;

EID: 9144253306     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2004.07.019     Document Type: Review

References (95)

1. L.L. Barrickman, P.J. Perry, A.J. Allen, S. Kuperman, S.V. Arndt, K.J. Herrmann, E. Schumacher Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder J Am Acad Child Adolesc Psychiatry 34 1995 649 657
2. R.G. Batey Alcohol related problems R.E. Rakel Conn's Current Therapy 2000 W.B. Saunders Philadelphia 1090 1093
3. E.S. Brown, V.A. Nejtek, D.C. Perantie, L. Bobadilla Quetiapine in bipolar disorder and cocaine dependence Bipolar Disord 4 2002 406 411
4. E.S. Brown, V.A. Nejtek, D.C. Perantie, P.J. Orsulak, L. Bobadilla Lamotrigine in patients with bipolar disorder and cocaine dependence J Clin Psychiatry 64 2003 197 201
5. P.F. Buckley Substance abuse in schizophrenia A review J Clin Psychiatry 59 1998 26 30
6. P.F. Buckley New antipsychotic agents Emerging clinical profiles J Clin Psychiatry 60 1999 12 17 ;discussion: 2830.
7. W.B. Daviss, P. Bentivoglio, R. Racusin, K.M. Brown, J.Q. Bostic, L. Wiley Bupropion sustained release in adolescents with comorbid attention-deficit/hyperactivity disorder and depression J Am Acad Child Adolesc Psychiatry 40 2001 307 314
8. D. Deas, S.E. Thomas An overview of controlled studies of adolescent substance abuse treatment Am J Addict 10 2001 178 189
9. S.L. Dewey, C.S. Chaurasia, C.E. Chen, N.D. Volkow, F.A. Clarkson, S.P. Porter GABAergic attenuation of cocaine-induced dopamine release and locomotor activity Synapse 25 1997 393 398
10. S.L. Dewey, A.E. Morgan, C.R. Ashby Jr, B. Horan, S.A. Kushner, J. Logan A novel strategy for the treatment of cocaine addiction Synapse 30 1998 119 129
11. G. Di Chiara, A. Imperato Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats Proc Natl Acad Sci U S A 85 1988 5274 5278
12. S.J. Donovan, J.W. Stewart, E.V. Nunes, F.M. Quitkin, M. Parides, W. Daniel Divalproex treatment for youth with explosive temper and mood lability A double-blind, placebo-controlled crossover design Am J Psychiatry 157 2000 818 820 [erratum appears in Am J Psychiatry 2000;157:1192]
13. D.W. Dunn, W.G. Kronenberger Attention-deficit/hyperactivity disorder in children and adolescents Neurol Clin 21 2003 933 940
14. H.M. Emrich, P. Vogt, A. Herz, W. Kissling Antidepressant effects of buprenorphine Lancet 2 1982 709 [letter]
15. G.J. Emslie, A.J. Rush, W.A. Weinberg, R.A. Kowatch, C.W. Hughes, T. Carmody, J. Rintelmann A double-blind, randomized, placebo-controlled trial of fluoxetine in children and adolescents with depression Arch Gen Psychiatry 54 1997 1031 1037
16. S.V. Faraone, J. Biederman, J. Wozniak, E. Mundy, D. Mennin, D. O'Donnell Is comorbidity with ADHD a marker for juvenile-onset mania? J Am Acad Child Adolesc Psychiatry 36 1997 1046 1055
17. C.K. Farren, F.A. Hameedi, M.A. Rosen, S. Woods, P. Jatlow, T.R. Kosten Significant interaction between clozapine and cocaine in cocaine addicts Drug Alcohol Depend 59 2000 153 163
18. M.A. Frye, L.L. Altshuler, S.L. McElroy, T. Suppes, P.E. Keck, K. Denicoff Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder Am J Psychiatry 160 2003 883 889
19. K. Fuxe, L.F. Agnati, M. Kalia, M. Goldstein, K. Anderson, A. Hartfstrand Dopaminergic systems in the brain and pituitary E. Fluckiger E.E. Muller M.O. Thorner Basic and Clinical Aspects of Neuroscience 1985 Springer-Verlag Berlin 11 25
20. B. Geller, T.B. Cooper, K. Sun, B. Zimerman, J. Frazier, M. Williams, J. Heath Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency [see comment] J Am Acad Child Adolesc Psychiatry 37 1998 171 178
21. B. Geller, J. Luby Child and adolescent bipolar disorder A review of the past 10 years J Am Acad Child Adolesc Psychiatry 36 1997 1168 1176 [see comment] [erratum appears in J Am Child Adolesc Psychiatry 1997;36:1642]
22. B. Geller, K. Sun, B. Zimerman, J. Luby, J. Frazier, M. Williams Complex and rapid-cycling in bipolar children and adolescents A preliminary study J Affect Disord 34 1995 259 268
23. B. Geller, B. Zimerman, M. Williams, K. Bolhofner, J.L. Craney, M.P. Delbello, C.A. Soutullo Diagnostic characteristics of 93 cases of a prepubertal and early adolescent bipolar disorder phenotype by gender, puberty and comorbid attention deficit hyperactivity disorder J Child Adolesc Psychopharmacol 10 2000 157 164
24. M.R. Gerasimov, S.L. Dewey Gamma-vinyl gamma-aminobutyric acid attenuates the synergistic elevations of nucleus accumbens dopamine produced by a cocaine/heroin (speedball) challenge Eur J Pharmacol 380 1999 1 4
25. G. Gonzalez, K. Sevarino, M. Sofuoglu, J. Poling, A. Oliveto, K. Gonsai Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients Results of a randomized pilot study Addiction 98 2003 1625 1632
26. J. Grabowski, H. Rhoades, P. Silverman, J.M. Schmitz, A. Stotts, D. Creson, R. Bailey Risperidone for the treatment of cocaine dependence Randomized, double-blind trial J Clin Psychopharmacol 20 2000 305 310
27. A.I. Green, S.V. Zimmet, R.D. Strous, J.J. Schildkraut Clozapine for comorbid substance use disorder and schizophrenia Do patients with schizophrenia have a reward-deficiency syndrome that can be ameliorated by clozapine? Harv Rev Psychiatry 6 1999 287 296
28. J.A. Halikas, B.A. Center, V.L. Pearson, G.A. Carlson, F. Crea A pilot, open clinical study of depakote in the treatment of cocaine abuse Hum Psychopharmacol 16 2001 257 264
29. J.R. Hughes, M.G. Goldstein, R.D. Hurt, S. Shiffman Recent advances in the pharmacotherapy of smoking JAMA 281 1999 72 76
30. R.D. Hurt, D.P. Sachs, E.D. Glover, K.P. Offord, J.A. Johnston, L.C. Dale A comparison of sustained-release bupropion and placebo for smoking cessation N Engl J Med 337 1997 1195 1202 [see comments]
31. B.A. Johnson, N. Ait-Daoud, C.L. Bowden, C.C. DiClemente, J.D. Roache, K. Lawson Oral topiramate for treatment of alcohol dependence A randomised controlled trial Lancet 361 2003 1677 1685 [see comment]
32. R.E. Johnson, M.A. Chutuape, E.C. Strain, S.L. Walsh, M.L. Stitzer, G.E. Bigelow A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence N Engl J Med 343 2000 1290 1297
33. K.M. Kampman, H. Pettinati, K.G. Lynch, C. Dackis, T. Sparkman, C. Weigley, C.P. O'Brien A pilot trial of topiramate for the treatment of cocaine dependence Drug Alcohol Depend 75 2004 233 240
34. K.M. Kampman, H. Pettinati, K.G. Lynch, T. Sparkman, C.P. O'Brien A pilot trial of olanzapine for the treatment of cocaine dependence Drug Alcohol Depend 70 2003 265 273
35. P.E. Keck, S.L. McElroy, S.M. Strakowski, T.M. Balistreri, D.I. Kizer, S.A. West Factors associated with maintenance antipsychotic treatment of patients with bipolar disorder J Clin Psychiatry 57 1996 147 151
36. W. Klein-Schwartz, J. McGrath Poison centers' experience with methylphenidate abuse in pre-teens and adolescents J Am Acad Child Adolesc Psychiatry 42 2003 288 294
37. G.F. Koob, F.E. Bloom Cellular and molecular mechanisms of drug dependence Science 242 1988 715 723
38. T.A. Kosten Enhanced neurobehavioral effects of cocaine with chronic neuroleptic exposure in rats Schizophr Bull 23 1997 203 213
39. T.R. Kosten Pathophysiology and treatment of cocaine dependence K.L. Davis D. Charney J.T. Coyle C. Nemeroff Neuropsychopharmacology The Fifth Generation of Progress 2002 Lippincott Williams and Wilkins Baltimore 1461 1473
40. T.R. Kosten, C.H. Morgan, T.A. Kosten Depressive symptoms during buprenorphine treatment of opioid abusers J Subst Abuse Treat 7 1990 51 54
41. T.R. Kosten, A.K. Singha Stimulants and related drugs G.O. Gabbard 3rd ed Treatments of Psychiatric Disorders vol I 2001 American Psychiatric Press Washington, DC 723 734
42. T.R. Kosten, D.M. Ziedonis Substance abuse and schizophrenia Schizophr Bull 23 1997 181 186
43. C.J. Kratochvil, J.H. Heiligenstein, R. Dittmann, T.J. Spencer, J. Biederman, J. Wernicke Atomoxetine and methylphenidate treatment in children with ADHD A prospective, randomized, open-label trial J Am Acad Child Adolesc Psychiatry 41 2002 776 784
44. J.H. Krystal, D.C. D'Souza, S. Madonick, I.L. Petrakis Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients Schizophr Res 35 1999 S35 S49
45. S.A. Kushner, S.L. Dewey, C. Kornetsky Gamma-vinyl GABA attenuates cocaine-induced lowering of brain stimulation reward thresholds Psychopharmacology (Berl) 133 1997 383 388
46. W. Ling, S. Shoptaw, D. Majewska Baclofen as a cocaine anti-craving medication A preliminary clinical study Neuropsychopharmacology 18 1998 403 404 [letter]
47. W. Ling, D.R. Wesson, C. Charuvastra, C.J. Klett A controlled trial comparing buprenorphine and methadone maintenance in opioid dependence Arch Gen Psychiatry 53 1996 401 407
48. K.H. Littrell, R.G. Petty, N.M. Hilligoss, C.D. Peabody, C.G. Johnson Olanzapine treatment for patients with schizophrenia and substance abuse J Subst Abuse Treat 21 2001 217 221
49. W. Loscher Basic pharmacology of valproate A review after 35 years of clinical use for the treatment of epilepsy CNS Drugs 16 2002 669 694
50. R. Malcolm, J.C. Ballenger, E.T. Sturgis, R. Anton Double-blind controlled trial comparing carbamazepine to oxazepam treatment of alcohol withdrawal Am J Psychiatry 146 1989 617 621
51. R. Malcolm, H. Myrick, K.T. Brady, J.C. Ballenger Update on anticonvulsants for the treatment of alcohol withdrawal Am J Addict 10 2001 16 23
52. R. Malcolm, H. Myrick, J. Roberts, W. Wang, R.F. Anton, J.C. Ballenger The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial J Gen Intern Med 17 2002 349 355 [see comment]
53. G.F. Marchesi, G. Santone, P. Cotani, A. Giordano, F. Chelli The therapeutic role of naltrexone in negative symptom schizophrenia Prog Neuropsychopharmacol Biol Psychiatry 19 1995 1239 1249
54. A. Markou, T.R. Kosten, G.F. Koob Neurobiological similarities in depression and drug dependence A self-medication hypothesis Neuropsychopharmacology 18 1998 135 174
55. J.E. Max, L. Richards, G. Hamdan-Allen Case study Antimanic effectiveness of dextroamphetamine in a brain-injured adolescent J Am Acad Child Adolesc Psychiatry 34 1995 472 476
56. D.M. McDowell, F.R. Levin, A.M. Seracini, E.V. Nunes Venlafaxine treatment of cocaine abusers with depressive disorders Am J Drug Alcohol Abuse 26 2000 25 31
57. J.P. McEvoy, O. Freudenreich, E.D. Levin, J.E. Rose Haloperidol increases smoking in patients with schizophrenia Psychopharmacology (Berl) 119 1995 124 126
58. K.R. Merikangas, R.L. Mehta, B.E. Molnar, E.E. Walters, J.D. Swendsen, S. Aguilar-Gaziola Comorbidity of substance use disorders with mood and anxiety disorders Results of the International Consortium in Psychiatric Epidemiology Addict Behav 23 1998 893 907
59. D. Michelson, A.J. Allen, J. Busner, C. Casat, D. Dunn, C. Kratochvil Once-daily atomoxetine treatment for children and adolescents with attention deficit hyperactivity disorder A randomized, placebo-controlled study Am J Psychiatry 159 2002 1896 1901
60. A.E. Morgan, S.L. Dewey Effects of pharmacologic increases in brain GABA levels on cocaine-induced changes in extracellular dopamine Synapse 28 1998 60 65
61. H. Myrick, S. Henderson, K.T. Brady, R. Malcom, M. Measom Divalproex loading in the treatment of cocaine dependence J Psychoactive Drugs 33 2001 283 287
62. T.F. Newton, W. Ling, A.D. Kalechstein, J. Uslaner, K. Tervo Risperidone pre-treatment reduces the euphoric effects of experimentally administered cocaine Psychiatry Res 102 2001 227 233
63. S.S. O'Malley Opioid antagonists in the treatment of alcohol dependence Clinical efficacy and prevention of relapse Alcohol Alcohol Suppl 1 1996 77 81
64. D.M. Platt, J.K. Rowlett, R.D. Spealman Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development Psychopharmacology (Berl) 163 2002 265 282
65. D.A. Regier, M.E. Farmer, D.S. Rae, B.Z. Locke, S.J. Keith, L.L. Judd, F.K. Goodwin Comorbidity of mental disorders with alcohol and other drug abuse JAMA 264 1990 2511 2518
66. P.D. Riggs, S.K. Hall, S.K. Mikulich-Gilbertson, M. Lohman, A. Kayser A randomized controlled trial of pemoline for attention-deficit/hyperactivity disorder in substance-abusing adolescents J Am Acad Child Adolesc Psychiatry 43 2004 420 429
67. P.D. Riggs, S.L. Leon, S.K. Mikulich, L.C. Pottle An open trial of bupropion for ADHD in adolescents with substance use disorders and conduct disorder J Am Acad Child Adolesc Psychiatry 37 1998 1271 1278
68. P.D. Riggs, S.K. Mikulich, L.M. Coffman, T.J. Crowley Fluoxetine in drug-dependent delinquents with major depression An open trial J Child Adolesc Psychopharmacol 7 1997 87 95
69. P.D. Riggs, L.L. Thompson, S.K. Mikulich, E.A. Whitmore, T.J. Crowley An open trial of pemoline in drug-dependent delinquents with attention-deficit hyperactivity disorder J Am Acad Child Adolesc Psychiatry 35 1996 1018 1024
70. M.C. Ritz, R.J. Lamb, S.R. Goldberg, M.J. Kuhar Cocaine receptors on dopamine transporters are related to self-administration of cocaine Science 237 1987 1219 1223
71. B.J. Rounsaville, Z.S. Dolinsky, T.F. Babor, R. Meyer Psychopathology as a predictor of treatment outcome in alcoholics Arch Gen Psychiatry 44 1987 505 513
72. B.J. Rounsaville, T.R. Kosten, M.M. Weissman, H.D. Kleber Prognostic significance of psychopathology in treated opiate addicts. A 2.5-year follow-up study Arch Gen Psychiatry 43 1986 739 745
73. A. Roy, M. Roy, D.A. Smelson Risperidone, ERG and cocaine craving Am J Addict 7 1998 90
74. D.J. Safer, J.M. Zito, J.E. Gardner Pemoline hepatotoxicity and postmarketing surveillance J Am Acad Child Adolesc Psychiatry 40 2001 622 629
75. I.M. Salloum, J.R. Cornelius, M.E. Thase, D.C. Daley, L. Kirisci, C. Spotts Naltrexone utility in depressed alcoholics Psychopharmacol Bull 34 1998 111 115
76. I.M. Salloum, M.E. Thase Impact of substance abuse on the course and treatment of bipolar disorder Bipolar Disord 2 2000 269 280
77. E.M. Sellers, D.A. Ciraulo, R.L. DuPont, R.R. Griffiths, T.R. Kosten, M.K. Romach, G.E. Woody Alprazolam and benzodiazepine abuse and dependence J Clin Psychiatry 54 1993 64 77
78. M.J. Sernyak, W.M. Glazer, G.R. Heninger, D.S. Charney, S.W. Woods, I.L. Petrakis Naltrexone augmentation of neuroleptics in schizophrenia J Clin Psychopharmacol 18 1998 248 251
79. M.J. Sernyak, L.S. Godleski, R.A. Griffin, C.M. Mazure, S.W. Woods Chronic neuroleptic exposure in bipolar outpatients J Clin Psychiatry 58 1997 193 195 [erratum appears in J Clin Psychiatry 1997;58:275]
80. M.J. Sernyak, D. Leslie, R. Rosenheck Use of system-wide outcomes monitoring data to compare the effectiveness of atypical neuroleptic medications Am J Psychiatry 160 2003 310 315
81. Y. Shaham, D. Highfield, J. Delfs, S. Leung, J. Stewart Clonidine blocks stress-induced reinstatement of heroin seeking in rats An effect independent of locus coeruleus noradrenergic neurons Eur J Neurosci 12 2000 292 302
82. W.T. Smith, P.D. Londborg, V. Glaudin, J.R. Painter Short-term augmentation of fluoxetine with clonazepam in the treatment of depression A double-blind study Am J Psychiatry 155 1998 1339 1345 [comment]
83. Summit Research Network W.T. Smith, P.D. Londborg, V. Glaudin, J.R. Painter Is extended clonazepam cotherapy of fluoxetine effective for outpatients with major depression? J Affect Disord 70 2002 251 259
84. K.N. Sokolski, C. Green, D.E. Maris, E.M. Demet Gabapentin as an adjunct to standard mood stabilizers in outpatients with mixed bipolar symptomatology Ann Clin Psychiatry 11 1999 217 222
85. T. Spencer, J.H. Heiligenstein, J. Biederman, D.E. Faries, C.J. Kratochvil, C.K. Conners, W.Z. Potter Results from 2 proof-of-concept, placebo-controlled studies of atomoxetine in children with attention-deficit/ hyperactivity disorder J Clin Psychiatry 63 2002 1140 1147
86. J. Stewart Pathways to relapse The neurobiology of drug- and stress-induced relapse to drug-taking J Psychiatry Neurosci 25 2000 125 136
87. J. Volavka The effects of clozapine on aggression and substance abuse in schizophrenic patients J Clin Psychiatry 60 1999 43 46
88. F. Waechter Paroxetine must not be given to patients under 18 BMJ 326 2003 1282
89. M. Watanabe, K. Maemura, K. Kanbara, T. Tamayama, H. Hayasaki GABA and GABA receptors in the central nervous system and other organs Int Rev Cytol 213 2002 1 47
90. R.D. Weiss, S.F. Greenfield, L.M. Najavits, J.A. Soto, D. Wyner, M. Tohen, M.L. Griffin Medication compliance among patients with bipolar disorder and substance use disorder J Clin Psychiatry 59 1998 172 174
91. T.E. Wilens, S.V. Faraone, J. Biederman, S. Gunawardene Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature Pediatrics 111 2003 179 185
92. T.E. Wilens, T.J. Spencer, J. Biederman, K. Girard, R. Doyle, J. Prince A controlled clinical trial of bupropion for attention deficit hyperactivity disorder in adults Am J Psychiatry 158 2001 282 288
93. J.N. Wilkins Pharmacotherapy of schizophrenia patients with comorbid substance abuse Schizophr Bull 23 1997 215 228
94. M.E. Willy, B. Manda, D. Shatin, C.R. Drinkard, D.J. Graham A study of compliance with FDA recommendations for pemoline (Cylert) J Am Acad Child Adolesc Psychiatry 41 2002 785 790
95. F. Yokoi, G. Grunder, K. Biziere, M. Stephane, A.S. Dogan, R.F. Dannals Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597) A study using positron emission tomography and [11C]raclopride Neuropsychopharmacology 27 2002 248 259