Randomized controlled trial of Siberian ginseng for chronic fatigue

Psychological Medicine

Volumn 34, Issue 1, 2004, Pages 51-61

  Hartz, Arthur J ^a,b,c,d,e   Bentler, S ^a,b,c,d,e   Noyes, R ^a,b,c,d,e   Hoehns, J ^a,b,c,d,e   Logemann, C ^a,b,c,d,e   Sinift, S ^a,b,c,d,e   Butani, Y ^a,b,c,d,e   Wang, W ^a,b,c,d,e   Brake, K ^a,b,c,d,e   Ernst, M ^a,b,c,d,e   Kautzman, H ^a,b,c,d,e  

^a UNIVERSITY OF IOWA   (United States)

^b Northeast Iowa Family Practice   (United States)

^c East Des Moines Family Care Center   (United States)

^d Cedar Rapids Family Practice   (United States)

^e Advanced Botanical Consulting   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GINSENG EXTRACT; PLACEBO;

ADULT; AGED; ARTICLE; BREAST TENDERNESS; CHRONIC FATIGUE SYNDROME; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; ELEUTHEROCOCCUS SENTICOSUS; FEMALE; FOLLOW UP; HEADACHE; HEART PALPITATION; HUMAN; INSOMNIA; MALE; NERVOUSNESS; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; STATISTICAL SIGNIFICANCE; UTERUS BLEEDING;

ADULT; AGED; DEPRESSION; ELEUTHEROCOCCUS; FATIGUE SYNDROME, CHRONIC; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PHYTOTHERAPY; PLACEBOS; QUESTIONNAIRES; TREATMENT OUTCOME;

EID: 9144220786     PISSN: 00332917     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0033291703008791     Document Type: Article

References (47)

1. Barsky, A. J., Cleary, P. D., Wyshak, G., Spitzer, R. L., Williams, J. B. & Klerman, G. L. (1992). A structural diagnostic interview for hypochondriasis: a proposed criterion standard. Journal of Nervous Mental Disorder 180, 20-27.
2. Blondel-Hill, E. & Shafran, S. D. (1993). Treatment of the chronic fatigue syndrome. A review and practical guide. Drugs 46, 639-651.
3. Blumenthal, M. (ed.) (1998). The Complete German Commission E Monographs Therapuetic Guide to Herbal Medicines, pp. 124-125. American Botanical Council, Austin, TX.
4. Brook, R. H., Ware, J. E., Davies-Avery, A., Stewart, A. L., Donald, C. A., Rogers, W. H., Williams, K. N. & Johnston, S. A. (1979). Overview of adult health status measures fielded in Rand's Health Insurance Study. Medical Care 7 (suppl. 17), 24-25.
5. Carr, A. C., Ghosh, A. & Ancill, R. J. (1983). Can a computer take a psychiatric history? Psychological Medicine 13, 151-158.
6. Cathebras, P. J., Robbins, J. M. & Kirmayer, L. J. (1992). Fatigue in primary care: prevalence, psychiatric comorbidity, illness behavior, and outcome. Journal of General Internal Medicine 7, 276-286.
7. Chalder, T., Berelowitz, G., Pawlikowska, T., Watts, L., Wessely, S., Wright, D. & Wallace, E. P. (1993). Development of a Fatigue Scale. Journal of Psychosomatic Research 37, 147-153.
8. Clark, M. R., Karen, W., Russo, J., Kith, P., Sintay, M. & Buchwald, D. (1995). Chronic fatigue: risk factors for symptom persistence in a 2 1/2-year follow-up study. American Journal of Medicine 98, 187-195.
9. Cope, H. (1992). Fatigue: a non-specific complaint? International Review of Psychiatry 4, 273-280.
10. David, A., Pelosi, A., McDonald, E. & Stephens, D. (1990). Tired, weak, or in need of rest: fatigue among general practice attenders. British Medical Journal 301, 1199-1202.
11. Eisenberg, D. M., Kessler, R. C., Foster, C., Norlock, F. E., Calkins, D. R. & Delbanco, T. L. (1993). Unconventional medicine in the United States - prevalence, costs, and patterns of use. New England Journal of Medicine 328, 246-252.
12. Eisenberg, D. M., Davis, R. B., Ettner, S. L., Appel, S., Wilkey, S., Van Rompey, M. & Kessler, R. C. (1998). Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. Journal of the American Medical Association 280, 1569-1575.
13. Ernst, E. (2002). The risk-benefit profile of commonly used herbal therapies: ginkgo, St John's Wort, ginseng, echinacea, saw palmetto and kava. Annals of Internal Medicine 136, 42-53.
14. Facts and Comparisons (2000). Eleutherococcus. The Review of Natural Products. Facts and Comparisons/Walters Kluwer Co.: St Louis, MO. (August, 2000.)
15. Farnsworth, N. R., Kinghorn, A. D., Soejarto, D. D. & Waller, D. P. (1985). Siberian ginseng (Eleutherococcus senticosus): current status as an adaptogen. In Economics and Medicinal Plant Research, vol. 1 (ed. H. Wagner, H. Hikino and N. R. Farnsworth), pp. 155-209. Academic Press: London.
16. Fukuda, K., Straus, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G. & Komaroff, A. (1994). The chronic fatigue syndrome: a comprehensive approach to its definition and study. Annals of Internal Medicine 121, 953-959.
17. Grossman, J. H., Barnet, G. O., McGuire, M. T. & Swedlow, D. B. (1971). Evaluation of computer-acquired patient histories. Journal of the American Medical Association 215, 1286-1291.
18. Gruenwald, J. P., Brendler, T., Jaenicke, C. & Fleming, T. (eds.) (1998). PDR for Herbal Remedies. Medical Economics Company, Inc.: Montvale, NJ.
19. Hartz, A. J., Kuhn, E. M., Bentler, S. E., Levine, P. H. & London, R. (1999). Prognostic factors for persons with chronic fatigue. Archives of Family Medicine 8, 495-501.
20. Hartz, A. J., Kuhn, E. M. & Levine, P. H. (1998). Characteristics of fatigued persons associated with features of chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome 4, 71-97.
21. Hickie, I., Lloyd, A., Hadzi-Pavlovic, D., Parker, G., Bird, K. & Wakefield, D. (1995). Can the chronic fatigue syndrome be defined by distinct clinical features? Psychological Medicine 25, 925-935.
22. Huang, T. (ed.) (1994). A Handbook of the Composition and Pharmacology of Common Chinese Drugs. Beijing, China: The Medical and Pharmaceutical Publishing of China: Beijing, China.
23. Janetzky, K. & Morreale, A. P. (1997). Probable interaction between warfarin and ginseng. American Journal of Health-System Pharmacy 54, 692-693.
24. Jason, L. J., Richman, J. A., Rademaker, A. W., Jordan, K. M., Plioplys, A. V., Taylor, R. R., McCready, W., Huang, C. F. & Plioplys, S. (1999). A community-based study of chronic fatigue syndrome. Archives of Internal Medicine 159, 2129-2137.
25. Khermouch, G. (1997). E-drinks a -go-go as Red Bull enters U.S. Brandweek 38, 8.
26. Kroenke, K., Wood, D. R., Mangelsdorff, D., Meier, N. J. & Powell, J. B. (1988). Chronic fatigue in primary care prevalence, patient characteristics, and outcome. Journal of American Medical Association 260, 929-934.
27. Lucas, R. W., Mullin, P. J., Luna, C. B. & McInroy, D. C. (1977). Psychiatrists and a computer as interrogators of patients with alcohol-related illnesses: a comparison. British Journal of Psychiatry 131, 160-167.
28. McMath, R. (1992). New products: broccoli, sports products boost the vitamin market. Brandweek 33, 41-45.
29. McRae, S. (1996). Elevated serum digoxin levels in a patient taking digoxin and Siberian ginseng. Canadian Medical Association Journal 155, 293-295.
30. Medical Advisor (1996). The Complete Guide to Alternative and Conventional Treatments. Time-Life Books: Alexandria, VA.
31. Murray, M. T. & Pizzorno, J. (1991). Encyclopedia of Natural Medicine. Prima Publishing: Rocklin, CA.
32. Murray, M. T. & Pizzorno, J. (1999). Textbook of Natural Medicine. Churchill Livingstone: New York.
33. National Center for Health Statistics (1978). The National-Ambulatory Medical Care Survey: 1975 Summary. National Center for Health Statistics 22-26: Hyattsville, MD.
34. Nelson, E., Kirk, J., McHugo, G. & Douglass, R. (1987). Summer. Chief complaint fatigue: a longitudinal study from the patient's perspective. Family Practice Research Journal 6, 175-188.
35. Ridsdale, L., Godfrey, E., Chalder, T., Seed, P., King, M., Wallace, P. & Wessely, S. (2001). Chronic fatigue in general practice: is counselling as good as cognitive behaviour therapy? A UK randomised trial. British Journal of General Practice 51, 19-24.
36. Rothman, R. J. (1990). No adjustments are needed for multiple comparisons. Epidemiology 1, 43-46.
37. SAS (1999). Statistical Software V8. SAS Institute Inc.: Cary, NC.
38. Sharpe, M. & Wilks, D. (2002). Fatigue. British Medical Journal 325, 480-483.
39. Sheehan, D. V., Lecrubier, Y., Harnett-Sheehan, K., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R. & Dunbar, G. C. (1998). The Mini International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic interview. Journal of Clinical Psychiatry 59 (suppl. 20), 22-33.
40. Solberg, L. I. (1984). Lassitude: a primary care evaluation. Journal of American Medical Association 251, 3272-3276.
41. Steele, L., Dobbins, J. G., Fukuda, K., Reyes, M., Randall, B., Koppelman, M. & Reeves, W. C. (1998). The epidemiology of chronic fatigue in San Francisco. American Journal of Medicine 105, 83S-90S.
42. Sugarman, J. R. & Berg, A. O. (1984). Evaluation of fatigue in a family practice. Journal of Family Practice 19, 643-647.
43. Valdini, A. F., Steinhardt, S., Valicenti, J. & Jaffe, A. (1988). A one-year follow-up of fatigued patients. Journal of Family Practice 26, 33-38.
44. Watson, D., Clark, L. A., Weber, K., Assenheimer, J. S., Strauss, M. E. & McCormick, R. A. (1995). Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. Journal of Abnormal Psychology 194, 15-25.
45. Weil, A. (1995). Spontaneous Healing: how to discover and enhance your body's natural ability to maintain and heal itself. 1st ed. Alfred A. Knopf, Inc.: New York.
46. Wessely, S., Chalder, T., Hirsch, S., Wallace, P. & Wright, D. (1997). The prevalence and morbidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care study. American Journal of Public Health 87, 1449-1455.
47. Whiting, P., Bagnall, A. M., Sowden, A. J., Cornell, J. E., Mulrow, C. D. & Ramirez, G. (2001). Interventions for the treatment and management of chronic fatigue syndrome: a systematic review. Journal of American Medical Association 286, 1360-1368.