메뉴 건너뛰기




Volumn 93, Issue 3, 1996, Pages 474-483

Acute cardiovascular effects of OPC-18790 in patients with congestive heart failure: Time- and dose-dependence analysis based on pressure-volume relations

Author keywords

cardiomyopathy; heart failure; hemodynamics; inotropic agents; quinolinone

Indexed keywords

LUSITROPIC; QUINOLINE DERIVATIVE; TOBORINONE; UNCLASSIFIED DRUG;

EID: 9044246667     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.93.3.474     Document Type: Article
Times cited : (79)

References (54)
  • 3
    • 0026738681 scopus 로고
    • Novel positive inotropic agents: Synthesis and biological activities of 6-(3-amino-2-hydroxypropoxy)-2(1H) -quinolinone derivatives
    • Fujioka T, Teramoto S, Mori T, Hosokawa T, Sumida T, Tominaga M, Yabuuchi Y. Novel positive inotropic agents: synthesis and biological activities of 6-(3-amino-2-hydroxypropoxy)-2(1H) -quinolinone derivatives. J Med Chem. 1992;35:3607-3612.
    • (1992) J Med Chem. , vol.35 , pp. 3607-3612
    • Fujioka, T.1    Teramoto, S.2    Mori, T.3    Hosokawa, T.4    Sumida, T.5    Tominaga, M.6    Yabuuchi, Y.7
  • 4
    • 0027372246 scopus 로고
    • Effects of OPC-18790, a new positive inotropic agent, on canine ventricular arrhythmias
    • Wu Z, Awaji T, Abe H, Motomura S, Hashimoto K. Effects of OPC-18790, a new positive inotropic agent, on canine ventricular arrhythmias. Jpn J Pharmacol. 1993;63:399-404.
    • (1993) Jpn J Pharmacol. , vol.63 , pp. 399-404
    • Wu, Z.1    Awaji, T.2    Abe, H.3    Motomura, S.4    Hashimoto, K.5
  • 5
    • 0028092005 scopus 로고
    • Effects of a novel inotropic agent (OPC-18790) on systolic and diastolic function in patients with severe heart failure
    • Hoit DB, Burwig S, Eppert D, Bhat G, Walsh RA. Effects of a novel inotropic agent (OPC-18790) on systolic and diastolic function in patients with severe heart failure. Am Heart J. 1994;128:1156-1163.
    • (1994) Am Heart J. , vol.128 , pp. 1156-1163
    • Hoit, D.B.1    Burwig, S.2    Eppert, D.3    Bhat, G.4    Walsh, R.A.5
  • 7
    • 0028226531 scopus 로고
    • Effects of a novel cardiotonic agent (±)-6-[3-(3,4-dimethoxybenzylamino)-2-hydroxypropoxy]-2(1H)-Quinolinone (OPC-18790) on contractile force, cyclic AMP level, and aequorin light transients in dog ventricular myocardium
    • Endoh M, Kawabata Y, Katano Y, Norota I. Effects of a novel cardiotonic agent (±)-6-[3-(3,4-dimethoxybenzylamino)-2-hydroxypropoxy]-2(1H)-Quinolinone (OPC-18790) on contractile force, cyclic AMP level, and aequorin light transients in dog ventricular myocardium. J Cardiovasc Pharmacol. 1994;23:723-730.
    • (1994) J Cardiovasc Pharmacol. , vol.23 , pp. 723-730
    • Endoh, M.1    Kawabata, Y.2    Katano, Y.3    Norota, I.4
  • 8
    • 0024344270 scopus 로고
    • 2(1H)-quinolinones with cardiac stimulant activity, III: Synthesis and biological properties of 6-imidazol-1-yl derivatives
    • Bell AS, Campbell SF, Morris DS, Roberts DA, Stefaniak MH. 2(1H)-quinolinones with cardiac stimulant activity, III: synthesis and biological properties of 6-imidazol-1-yl derivatives. J Med Chem. 1989;32:1552-1558.
    • (1989) J Med Chem. , vol.32 , pp. 1552-1558
    • Bell, A.S.1    Campbell, S.F.2    Morris, D.S.3    Roberts, D.A.4    Stefaniak, M.H.5
  • 9
    • 0023101566 scopus 로고
    • Membrane current changes responsible for the positive inotropic effect of OPC-8212, a new positive inotropic agent, in single ventricular cells of the guinea pig heart
    • Iijima T, Taira N. Membrane current changes responsible for the positive inotropic effect of OPC-8212, a new positive inotropic agent, in single ventricular cells of the guinea pig heart. J Pharmacol Exp Ther. 1987;240:657-662.
    • (1987) J Pharmacol Exp Ther. , vol.240 , pp. 657-662
    • Iijima, T.1    Taira, N.2
  • 10
    • 0025219356 scopus 로고
    • Voltage-dependent inhibition of the delayed outward potassium current by OPC-8490, a novel positive inotropic agent, in isolated atrial myocytes of guinea-pig heart
    • Kurachi Y, Asano Y, Ho H, Sugimoto T. Voltage-dependent inhibition of the delayed outward potassium current by OPC-8490, a novel positive inotropic agent, in isolated atrial myocytes of guinea-pig heart. Naunyn Schmiedebergs Arch Pharmacol. 1990;341: 324-330.
    • (1990) Naunyn Schmiedebergs Arch Pharmacol. , vol.341 , pp. 324-330
    • Kurachi, Y.1    Asano, Y.2    Ho, H.3    Sugimoto, T.4
  • 12
    • 0023130366 scopus 로고
    • Deficient production of cyclic AMP: Pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure
    • Feldman MD, Copelas L, Gwathmey JK, Phillips P, Warren SE, Schoen FJ, Grossman W, Morgan JP. Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure. Circulation. 1987;75:331-339.
    • (1987) Circulation , vol.75 , pp. 331-339
    • Feldman, M.D.1    Copelas, L.2    Gwathmey, J.K.3    Phillips, P.4    Warren, S.E.5    Schoen, F.J.6    Grossman, W.7    Morgan, J.P.8
  • 13
    • 9044229435 scopus 로고
    • Inotropic action of OPC-18790 in the isolated failing and nonfailing human heart
    • Abstract
    • Roden RL, Mitchusson KD, Skerl L, Bristow MR. Inotropic action of OPC-18790 in the isolated failing and nonfailing human heart. J Am Coll Cardiol. 1993;21:365A. Abstract.
    • (1993) J Am Coll Cardiol. , vol.21
    • Roden, R.L.1    Mitchusson, K.D.2    Skerl, L.3    Bristow, M.R.4
  • 14
    • 0023796309 scopus 로고
    • Use of a conductance (volume) catheter and transient inferior vena caval occlusion for rapid determination of pressure-volume relationships in man
    • Kass DA, Midei M, Graves W, Maughan WL. Use of a conductance (volume) catheter and transient inferior vena caval occlusion for rapid determination of pressure-volume relationships in man. Cathet Cardiovasc Diagn. 1988;15:192-202.
    • (1988) Cathet Cardiovasc Diagn. , vol.15 , pp. 192-202
    • Kass, D.A.1    Midei, M.2    Graves, W.3    Maughan, W.L.4
  • 15
    • 0027453362 scopus 로고
    • Stereoselectivc high-performance liquid chromatographic assay for the determination of OPC-18790 enantiomers in human plasma and urine
    • Kitani M, Miyamoto G, Odomi M. Stereoselectivc high-performance liquid chromatographic assay for the determination of OPC-18790 enantiomers in human plasma and urine. J Chromatogr B Biomed Appl. 1993;620:97-104.
    • (1993) J Chromatogr B Biomed Appl. , vol.620 , pp. 97-104
    • Kitani, M.1    Miyamoto, G.2    Odomi, M.3
  • 17
    • 0026496226 scopus 로고
    • Determination of left ventricular volume using a conductance catheter in the diseased human heart
    • Odake M, Takeuchi M, Takaoka H, Hata K, Hayashi Y, Yokoyama M. Determination of left ventricular volume using a conductance catheter in the diseased human heart. Eur Heart J. 1992;13(suppl E):22-27.
    • (1992) Eur Heart J. , vol.13 , Issue.SUPPL. E , pp. 22-27
    • Odake, M.1    Takeuchi, M.2    Takaoka, H.3    Hata, K.4    Hayashi, Y.5    Yokoyama, M.6
  • 18
    • 0014847138 scopus 로고
    • Left ventricular volume and mass from single-plane cineangiocardiogram
    • Kennedy JW, Trenholme SE, Kasser IS. Left ventricular volume and mass from single-plane cineangiocardiogram. Am Heart J. 1970; 80:343-352.
    • (1970) Am Heart J. , vol.80 , pp. 343-352
    • Kennedy, J.W.1    Trenholme, S.E.2    Kasser, I.S.3
  • 19
    • 0027067784 scopus 로고
    • Comparison of single and biplane ventriculography for determination of left ventricular volume and ejection fraction
    • Brogan WC III, Glamann B, Lange RA, Hillis LD. Comparison of single and biplane ventriculography for determination of left ventricular volume and ejection fraction. Am J Cardiol. 1992;69: 1079-1082.
    • (1992) Am J Cardiol. , vol.69 , pp. 1079-1082
    • Brogan III, W.C.1    Glamann, B.2    Lange, R.A.3    Hillis, L.D.4
  • 20
    • 0020858768 scopus 로고
    • Left ventricular interaction with arterial load studied in isolated canine ventricle
    • Sunagawa K, Maughan WL, Burkhoff D, Sagawa K. Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol. 1983;245:H773-H780.
    • (1983) Am J Physiol. , vol.245
    • Sunagawa, K.1    Maughan, W.L.2    Burkhoff, D.3    Sagawa, K.4
  • 22
    • 0016280920 scopus 로고
    • Instantaneous pressure-volume relationships and their ratio in the excised, supported canine left ventricle
    • Suga H, Sagawa K. Instantaneous pressure-volume relationships and their ratio in the excised, supported canine left ventricle. Circ Res. 1974;35:117-128.
    • (1974) Circ Res. , vol.35 , pp. 117-128
    • Suga, H.1    Sagawa, K.2
  • 23
    • 0023481279 scopus 로고
    • Comparative influence of load versus inotropic states on indexes of ventricular contractility: Experimental and theoretical analysis based on pressure-volume relationships
    • Kass DA, Maughan WL, Guo ZM, Kono A, Sunagawa K, Sagawa K. Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation. 1987;76: 1422-1436.
    • (1987) Circulation , vol.76 , pp. 1422-1436
    • Kass, D.A.1    Maughan, W.L.2    Guo, Z.M.3    Kono, A.4    Sunagawa, K.5    Sagawa, K.6
  • 25
    • 0028295432 scopus 로고
    • Ventricular systolic assessment in patients with dilated cardiomyopathy by preload-adjusted maximal power: Validation and noninvasive application
    • Sharir T, Haber H, Feldman M, Marmor A, Becker LC, Kass DA. Ventricular systolic assessment in patients with dilated cardiomyopathy by preload-adjusted maximal power: validation and noninvasive application. Circulation. 1994;89:2045-2053.
    • (1994) Circulation , vol.89 , pp. 2045-2053
    • Sharir, T.1    Haber, H.2    Feldman, M.3    Marmor, A.4    Becker, L.C.5    Kass, D.A.6
  • 26
    • 0024408937 scopus 로고
    • Ventriculoarterial coupling in normal and failing heart in humans
    • Asanoi H, Sasayama S, Kameyama T. Ventriculoarterial coupling in normal and failing heart in humans. Circ Res. 1989;65:483-493.
    • (1989) Circ Res. , vol.65 , pp. 483-493
    • Asanoi, H.1    Sasayama, S.2    Kameyama, T.3
  • 27
    • 0021993531 scopus 로고
    • Optimal arterial resistance for maximal stroke work studied in isolated canine ventricle
    • Sunagawa K, Maughan WL, Sagawa K. Optimal arterial resistance for maximal stroke work studied in isolated canine ventricle. Circ Res. 1985;56:586-595.
    • (1985) Circ Res. , vol.56 , pp. 586-595
    • Sunagawa, K.1    Maughan, W.L.2    Sagawa, K.3
  • 28
    • 0027177910 scopus 로고
    • Ventricular stroke work and efficiency both remain nearly optimal despite altered vascular loading
    • de Tombe PP, Jones S, Burkhoff D, Hunter WC, Kass DA. Ventricular stroke work and efficiency both remain nearly optimal despite altered vascular loading. Am J Physiol. 1993;264: H1817-H1824.
    • (1993) Am J Physiol. , vol.264
    • De Tombe, P.P.1    Jones, S.2    Burkhoff, D.3    Hunter, W.C.4    Kass, D.A.5
  • 29
    • 0020024492 scopus 로고
    • Work as correlate of canine left ventricular oxygen consumption, and the problem of oxygen wasting
    • Rooke GA, Feigl EO. Work as correlate of canine left ventricular oxygen consumption, and the problem of oxygen wasting. Circ Res. 1982;50:273-286.
    • (1982) Circ Res. , vol.50 , pp. 273-286
    • Rooke, G.A.1    Feigl, E.O.2
  • 30
    • 0027958764 scopus 로고
    • Relation between ventriculoarterial coupling and myocardial energetics in patients with idiopathic dilated cardiomyopathy
    • Ishihara H, Yokota M, Sobue T, Saito H. Relation between ventriculoarterial coupling and myocardial energetics in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol. 1994;23: 406-416.
    • (1994) J Am Coll Cardiol. , vol.23 , pp. 406-416
    • Ishihara, H.1    Yokota, M.2    Sobue, T.3    Saito, H.4
  • 32
    • 0024581926 scopus 로고
    • Influence of contractile state on curvilinearity of in situ end-systolic pressure-volume relations
    • Kass DA, Beyar R, Lankford EB, Heard M, Maughan WL, Sagawa K. Influence of contractile state on curvilinearity of in situ end-systolic pressure-volume relations. Circulation. 1989;79:167-178.
    • (1989) Circulation , vol.79 , pp. 167-178
    • Kass, D.A.1    Beyar, R.2    Lankford, E.B.3    Heard, M.4    Maughan, W.L.5    Sagawa, K.6
  • 33
    • 0023242325 scopus 로고
    • Influence of heart rate on left ventricular performance in conscious dogs
    • Freeman GL, Little WC, O'Rourke RA. Influence of heart rate on left ventricular performance in conscious dogs. Circ Res. 1987;61: 455-464.
    • (1987) Circ Res. , vol.61 , pp. 455-464
    • Freeman, G.L.1    Little, W.C.2    O'Rourke, R.A.3
  • 34
    • 0027372973 scopus 로고
    • Diminished contractile response to increased heart rate in intact human left ventricular hypertrophy: Systolic versus diastolic determinants
    • Liu CP, Lawrence W, Ting CT, Chang MS, Maughan WL, Kass DA. Diminished contractile response to increased heart rate in intact human left ventricular hypertrophy: systolic versus diastolic determinants. Circulation. 1993;88:1893-1906.
    • (1993) Circulation , vol.88 , pp. 1893-1906
    • Liu, C.P.1    Lawrence, W.2    Ting, C.T.3    Chang, M.S.4    Maughan, W.L.5    Kass, D.A.6
  • 35
    • 0026441419 scopus 로고
    • Positive inotropic and lusitropic effects of intravenous flosequinan in patients with heart failure
    • Burstein S, Semigran MJ, Dec GW Jr, Boucher CA, Fifer MA. Positive inotropic and lusitropic effects of intravenous flosequinan in patients with heart failure. J Am Coll Cardial. 1992;20:822-829.
    • (1992) J Am Coll Cardial. , vol.20 , pp. 822-829
    • Burstein, S.1    Semigran, M.J.2    Dec Jr., G.W.3    Boucher, C.A.4    Fifer, M.A.5
  • 36
    • 0023217915 scopus 로고
    • Inotropic effect of enoximone in patients with severe heart failure: Demonstration by left ventricular end-systolic pressure-volume analysis
    • Herrmann HC, Ruddy TD, William G, Strauss HW, Boucher CA, Fifer MA. Inotropic effect of enoximone in patients with severe heart failure: demonstration by left ventricular end-systolic pressure-volume analysis. J Am Coll Cardiol. 1987;9:1117-1123.
    • (1987) J Am Coll Cardiol. , vol.9 , pp. 1117-1123
    • Herrmann, H.C.1    Ruddy, T.D.2    William, G.3    Strauss, H.W.4    Boucher, C.A.5    Fifer, M.A.6
  • 37
    • 9044242336 scopus 로고
    • + channel blocking activity of the vesnarinone analog OPC-18790
    • Abstract
    • + channel blocking activity of the vesnarinone analog OPC-18790. Circulation. 1994; 90(suppl I):I-146. Abstract.
    • (1994) Circulation , vol.90 , Issue.1 SUPPL.
    • Yang, T.1    Snyders, D.J.2    Roden, D.M.3
  • 38
    • 0022001187 scopus 로고
    • Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure: Dose-response relationships and comparison to nitroprusside
    • Jaski BE, Fifer MA, Wright RF, Braunwald E, Colucci WS. Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure: dose-response relationships and comparison to nitroprusside. J Clin Invest. 1985;75:643-649.
    • (1985) J Clin Invest. , vol.75 , pp. 643-649
    • Jaski, B.E.1    Fifer, M.A.2    Wright, R.F.3    Braunwald, E.4    Colucci, W.S.5
  • 40
    • 0027377452 scopus 로고
    • Amrinone in cardiac surgical patients with left-ventricular dysfunction: A prospective, randomized placebo-controlled trial
    • Butterworth JF IV, Royster RL, Prielipp RC, Lawless ST, Wallenhaupt SL. Amrinone in cardiac surgical patients with left-ventricular dysfunction: a prospective, randomized placebo-controlled trial. Chest. 1993;104:1660-1667.
    • (1993) Chest , vol.104 , pp. 1660-1667
    • Butterworth IV, J.F.1    Royster, R.L.2    Prielipp, R.C.3    Lawless, S.T.4    Wallenhaupt, S.L.5
  • 41
    • 0028961166 scopus 로고
    • Differential effects of OPC-18790, amrinone, and dobutamine on cardiac function and energy metabolism in the guinea-pig isolated ischaemic heart
    • Itoh S, Mori T, Tominaga M, Ishikawa M, Koga K, Yabuuchi Y. Differential effects of OPC-18790, amrinone, and dobutamine on cardiac function and energy metabolism in the guinea-pig isolated ischaemic heart. Br J Pharmacol. 1995;114:1090-1096.
    • (1995) Br J Pharmacol. , vol.114 , pp. 1090-1096
    • Itoh, S.1    Mori, T.2    Tominaga, M.3    Ishikawa, M.4    Koga, K.5    Yabuuchi, Y.6
  • 42
    • 0026045663 scopus 로고
    • Usefulness of OPC-8212, a quinolinonc derivative, for chronic congestive heart failure in patients with ischemic heart disease or idiopathic dilated cardiomyopathy
    • Feldman AM, Baughman KL, Lee WK, Gottlieb SH, Weiss JL, Becker LC, Strobeck JE. Usefulness of OPC-8212, a quinolinonc derivative, for chronic congestive heart failure in patients with ischemic heart disease or idiopathic dilated cardiomyopathy. Am J Cardiol. 1991;68:1203-1210.
    • (1991) Am J Cardiol. , vol.68 , pp. 1203-1210
    • Feldman, A.M.1    Baughman, K.L.2    Lee, W.K.3    Gottlieb, S.H.4    Weiss, J.L.5    Becker, L.C.6    Strobeck, J.E.7
  • 44
    • 0028326215 scopus 로고
    • Quinolinone derivatives in the management of congestive heart failure
    • Feldman AM, Strobeck JE. Quinolinone derivatives in the management of congestive heart failure. Coron Artery Dis. 1994;5: 107-111.
    • (1994) Coron Artery Dis. , vol.5 , pp. 107-111
    • Feldman, A.M.1    Strobeck, J.E.2
  • 46
    • 0024616409 scopus 로고
    • Long-term oral therapy of congestive heart failure with phosphodiesterase inhibitors
    • Wood MA, Hess ML. Long-term oral therapy of congestive heart failure with phosphodiesterase inhibitors. Am J Med Sci. 1989;297: 105-113.
    • (1989) Am J Med Sci. , vol.297 , pp. 105-113
    • Wood, M.A.1    Hess, M.L.2
  • 47
    • 0027299012 scopus 로고
    • Left ventricular-arterial coupling relations in the normal human heart
    • Starling MR. Left ventricular-arterial coupling relations in the normal human heart. Am Heart J. 1993;125:1659-1666.
    • (1993) Am Heart J. , vol.125 , pp. 1659-1666
    • Starling, M.R.1
  • 48
    • 0026102121 scopus 로고
    • Ventricular-load optimization by inotropic stimulation in patients with heart failure
    • Ishizaka S, Asanoi H, Kameyama T, Sasayama S. Ventricular-load optimization by inotropic stimulation in patients with heart failure. Int J Cardiol. 1991;31:51-58.
    • (1991) Int J Cardiol. , vol.31 , pp. 51-58
    • Ishizaka, S.1    Asanoi, H.2    Kameyama, T.3    Sasayama, S.4
  • 49
    • 0026099801 scopus 로고
    • Ventricular load optimization by unloading therapy in patients with heart failure
    • Kameyama T, Asanoi H, Ishizaka S, Sasayama S. Ventricular load optimization by unloading therapy in patients with heart failure. J Am Coll Cardiol. 1991;17:199-207.
    • (1991) J Am Coll Cardiol. , vol.17 , pp. 199-207
    • Kameyama, T.1    Asanoi, H.2    Ishizaka, S.3    Sasayama, S.4
  • 50
    • 8244239438 scopus 로고
    • Beneficial effects of OPC-18790 on mechanoenergetics in patients with idiopathic dilated cardiomyopathy
    • Abstract
    • Kanda H, Ishihara H, Nagata K, Kato R, Sobue T, Yokota M. Beneficial effects of OPC-18790 on mechanoenergetics in patients with idiopathic dilated cardiomyopathy. Am J Coll Cardiol. 1995; 25:165A. Abstract.
    • (1995) Am J Coll Cardiol. , vol.25
    • Kanda, H.1    Ishihara, H.2    Nagata, K.3    Kato, R.4    Sobue, T.5    Yokota, M.6
  • 51
    • 0025277221 scopus 로고
    • Does volume catheter parallel conductance vary during a cardiac cycle?
    • Lankford EB, Kass DA, Maughan WL, Shoukas AA. Does volume catheter parallel conductance vary during a cardiac cycle? Am J Physiol. 1990;258:H1933-H1942.
    • (1990) Am J Physiol. , vol.258
    • Lankford, E.B.1    Kass, D.A.2    Maughan, W.L.3    Shoukas, A.A.4
  • 53
    • 0024829664 scopus 로고
    • Determinants of end-systolic pressure-volume relations during acute regional ischemia in situ
    • Kass DA, Marino PM, Maughan WL, Sagawa K. Determinants of end-systolic pressure-volume relations during acute regional ischemia in situ. Circulation. 1989;80:1783-1794.
    • (1989) Circulation , vol.80 , pp. 1783-1794
    • Kass, D.A.1    Marino, P.M.2    Maughan, W.L.3    Sagawa, K.4
  • 54
    • 0021983693 scopus 로고
    • Hemodynamic changes mimicking a vasodilator drug response in the absence of drug therapy after right heart catheterization in patients with chronic heart failure
    • Packer M, Medine N, Yushak M. Hemodynamic changes mimicking a vasodilator drug response in the absence of drug therapy after right heart catheterization in patients with chronic heart failure. Circulation. 1985;71:761-766.
    • (1985) Circulation , vol.71 , pp. 761-766
    • Packer, M.1    Medine, N.2    Yushak, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.