Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse

Japanese Journal of Pharmacology

Volumn 70, Issue 1, 1996, Pages 85-88

  Manabe, Noboru ^a   Sugimoto, Miki ^a   Azuma, Yasuyoshi ^a   Taketomo, Naoki ^b   Yamashita, Akio ^b   Tsuboi, Hiroshi ^b   Tsunoo, Akinobu ^b   Kinjo, Noriko ^c   Nian Lai, Huang ^d   Miyamoto, Hajime ^a  

^a KYOTO UNIVERSITY   (Japan)

^b MEIJI DAIRIES CORPORATION   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d Sanming Mycological Institute   (China)

Author keywords

Liver energy state; Phosphorus 31 nuclear magnetic resonance (NMR) (in vivo)

Indexed keywords

CORDYCEPS SINENSIS EXTRACT; PHOSPHORUS 31;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PH; CHINESE MEDICINE; CONTROLLED STUDY; DRUG SAFETY; ENERGY METABOLISM; LIVER HISTOLOGY; LIVER METABOLISM; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ORAL DRUG ADMINISTRATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE;

EID: 9044233635     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.70.85     Document Type: Article

References (15)

1. Hamada M: Effect of Cordyceps sinensis (Berk.) Sacc. extract upon anti-tumor activity and tumor immunity. J Kanazawa Med Univ 16, 46-54 (1991)
2. Yoshida J, Takamura S, Suzuki S and Koshimura S: Potentiating effect of an extract of Cordyceps sinensis (Berk.) Sacc. on cytostatic activity of mouse effector cells against tumor cells. J Kanazawa Med Univ 17, 330-335 (1992)
3. 6-(2- Hydroxyethyl) adenosine, a biologically active compound from cultured mycelia of Cordyceps and Isaria species. Phytochemistry 22, 2509-2512 (1983)
4. Chatterjee R, Srinivasan KS and Maiti PC: Cordyceps sinensis (Berkeley) Saccardo: Structure of Cordycepic acid. J Am Pharmaceut Assoc 66, 114-118 (1957)
5. Tsunoo A, Taketomo N, Kamijo M, Yamashita A, Kinjo N, and Huang N : Pharmacological effects of the mycelial extract of cultured Cordyceps sinensis on airways and aortae of the rat. In Mushroom Science, Vol XIV, Science and Cultivation of Edible Fungi, Edited by Elliott TJ, pp 425-431, Balkema, Rotterdam (1995)
6. 31P nuclear magnetic resonance study in rats. Hepatology 11, 65-73 (1990)
7. Geoffrion Y, Rydzy M, Butler KW, Smith ICP and Jarrell HC: The use of immobilized ferrite to enhance the depth selectivity of in vivo surface coil NMR spectroscopy. NMR Biomed 1, 107-112 (1988)
8. Azuma Y, Manabe N, Kawai F, Kanamori M and Miyamoto H: Phosphorus-31 nuclear magnetic resonance study of energy metabolism in intact slow- and fast-twitch muscles of rats. J Anim Sci 72, 103-108 (1994)
9. 31P-NMR spectroscopy. Biochim Biophys Acta 885, 1-11 (1986)
10. 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR Biomed 1, 67-73 (1988)
11. 31P NMR spectroscopy as an indicator of chemically induced hepatic toxicity in the rat: Comparison with serum enzyme levels and pathology. NMR Biomed 4, 12-15 (1991)
12. 31P NMR spectroscopy. Magn Reson Med 20, 100-112 (1991)
13. Ozawa K, Yamaoka Y, Nannbu H and Honjo I: Insulin as the primary factor governing changes in mitochondrial metabolism leading to liver regeneration and atrophy. Am J Surg 127, 669-675 (1974)
14. Niwano Y, Konaka S, Uchida M and Sugimoto T: Activation of mitochondrial functions by malotilate in relation to accelerated liver regeneration in partial hepatectomized rats. Jpn J Pharmacol 42, 525-529 (1986)
15. Desmoulin F, Canioni P, Crotte C, Gérolami A and Cozzone PJ: Hepatic metabolism during acute ethanol administration: A phosphorus-31 nuclear magnetic resonance study on the perfused rat liver under normoxic or hypoxic conditions. Hepatology 7, 315-327 (1987)