The role of insulin in the interaction of secretin and cholecystokinin in exocrine secretion of the isolated perfused rat pancreas

Pancreas

Volumn 12, Issue 1, 1996, Pages 58-63

  Lee, Yun Lyul ^a   Kwon, Hyeok Yil ^a   Park, Hyung Seo ^a   Lee, Tae Hyung ^a   Park, Hyoung Jin ^a  

^a Hallym University   (South Korea)

Author keywords

Cholecystokinin; Insulin; Isolated pancreas; Pancreatic exocrine secretion; Rat; Secretin

Indexed keywords

AMYLASE; CHOLECYSTOKININ; CHOLECYSTOKININ OCTAPEPTIDE; GLUCOSE; INSULIN; SECRETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS SECRETION; POSTPRANDIAL STATE; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 9044230528     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199601000-00007     Document Type: Article

References (17)

1. You CH, Rominger JM, Chey WY. Potentiation effect of cholecystokinin-octapeptide on pancreatic bicarbonate secretion stimulated by a physiologic dose of secretin in humans. Gastroenterology 1983;85:40-5.
2. Henricksen FW, Worning H. The interaction of secretin and pancreozymin on the external pancreatic secretion in dogs. Acta Physiol Scand 1967;70:241-9.
3. Meyer JH, Spingola LJ, Grossman MI. Endogenous cholecystokinin potentiates exogenous secretin on pancreas of dogs. Am J Physiol 1971;221:742-7.
4. Chey WY, Lee KY, Chang T-M, Chen F-Y, Millikan L. Potentiating effect of secretin on cholecystokinin-stimulated pancreatic secretion in dogs. Am J Physiol 1984;246:G248-52.
5. Chey WY, Shay H, Schuman CR. External pancreatic secretion in diabetes mellitus. Ann Intern Med 1963;59:812-21.
6. Vacca JB, Henke WJ, Knight WA Jr. The exocrine secretion in diabetes mellitus. Ann Intern Med 1964;61:242-7.
7. Domschke W, Tympner F, Domschke S, Demling L. Exocrine pancreatic function in juvenile diabetes. Dig Dis 1975; 20:309-12.
8. Frier BM, Faber OK, Binder C, Elliott HL. The effect of residual insulin secretion on exocrine pancreatic function in juvenile-onset diabetes mellitus. Diabetologia 1978;14: 301-4.
9. Lee KY, Zhou L, Ren XS, Chang T-M, Chey WY. An important role of endogenous insulin on exocrine pancreatic secretion in rats. Am J Physiol 1990;258:G268-74.
10. Kanno T, Saito A. The potentiating influences of insulin on pancreozymin-induced hyperpolarization and amylase release in the pancreatic acinar cell. J Physiol (Lond) 1976; 261:505-21.
11. Saito A, Williams JA, Kanno T. Potentiation of cholecystokinin-induced exocrine secretion of both exogenous and endogenous insulin in isolated and perfused rat pancreata. J Clin Invest 1980;65:777-82.
12. Garry DJ, Garry MG, Williams JA, Mahoney WC, Sorensen RL. Effects of islet hormones on amylase secretion and localization of somatostatin binding sites. Am J Physiol 1989; 256:G897-904.
13. Park HJ, Lee YL, Kwon HY. Effects of pancreatic polypeptide on insulin action in exocrine secretion of isolated rat pancreas. J Physiol (Lond) 1993;463:421-9.
14. Okabayashi Y, Otsuki M, Ohki A, Nakamura T, Tani S, Baba S. Secretin-induced exocrine secretion in perfused pancreas isolated from diabetic rats. Diabetes 1988;37:1173-80.
15. Sofrankova A, Dockray GJ. Cholecystokinin- and secretin-induced pancreatic secretion in normal and diabetic rats. Am J Physiol 1983;244:G370-4.
16. Rick W, Stegbauer HP. α-Amylase; measurement of reducing groups. In: Bergermeyer HU, ed. Methods of enzymatic analysis, Volume 2, 2nd ed. Weinheim: Verlag Chemie, 1974:885-915.
17. Matsushita K, Okabayashi Y, Koide M, Hasegawa H, Otsuki M, Kasuga M. Potentiating effect of insulin on exocrine secretory function in isolated rat pancreatic acini. Gastroenterology 1994;106:200-6.