Interruption of the gpxA gene increases the sensitivity of Neisseria meningitidis to paraquat

Journal of Bacteriology

Volumn 178, Issue 14, 1996, Pages 4301-4305

  Moore, Tracey D E ^a,b   Frederick Sparling, P ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; PARAQUAT;

AEROBIC METABOLISM; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; DRUG SENSITIVITY; GENE INSERTION; IMMUNOBLOTTING; INFECTION; NEISSERIA MENINGITIDIS; NONHUMAN; NORTHERN BLOTTING; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 8944258926     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.14.4301-4305.1996     Document Type: Article

References (42)

1. Ames, B. N., and M. K. Shigenaga. 1992. DNA damage by endogenous oxidants and mitogenesis as causes of aging and cancer, p. 1-22. In J. G. Scandalios (ed.), Molecular biology of free radical scavenging systems. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
2. Archibald, F., and M. Duong. 1986. Superoxide dismutase and oxygen toxicity defenses in the genus Neisseria. Infect. Immun. 51:631-641.
3. Benov, L. T., and I. Fridovich. 1994. Escherichia coli expresses a copper- and zinc-containing superoxide dismutase. J. Biol. Chem. 269:25310-25314.
4. Biswas, G. D., D. W. Dyer, M. K. Thompson, and P. F. Sparling. 1986. Construction of isogenic gonococcal strains varying in the presence of a 4.2-kilobase cryptic plasmid. J. Bacteriol. 167:685-694.
5. Brigelius-Flohe, R., K. Aumann, H. Blocker, G. Gross, M. Kiess, K. Kloppel, M. Maiorino, A. Roveri, R. Schuckelt, F. Ursini, E. Wingender, and L. Flohe. 1994. Phospholipid-hydroperoxide glutathione peroxidase. J. Biol. Chem. 269:7342-7348.
6. Carlioz, A., and D. Touati. 1986. Isolation of superoxide dismutase mutants in Escherichia coli: is superoxide dismutase necessary for aerobic life? EMBO J. 5:623-630.
7. Cha, M., H. Kim, and I. Kim. 1995. Thioredoxin-linked "thiol peroxidase" from periplasmic space of Escherichia coli. J. Biol. Chem. 270:28635-28641.
8. Chae, H. Z., S. J. Chung, and S. G. Rhee. 1994. Thioredoxin-dependent peroxide reductase from yeast. J. Biol. Chem. 269:27670-27678.
9. Del Sal, G., G. Manfioletti, and C. Schneider. 1988. A one-tube plasmid DNA mini-preparation suitable for sequencing. Nucleic Acids Res. 16:9878.
10. 12 transport in Escherichia coli. J. Bacteriol. 167:920-927.
11. Dyer, D. W., W. McKenna, J. P. Woods, and P. F. Sparling. 1987. Isolation by streptonigrin enrichment and characterization of a transferrin-specific iron uptake mutant of Neisseria meningitidis. Microb. Pathog. 3:351-363.
12. Fair, S. B., D. Touati, and T. Kogoma. 1988. Effects of oxygen stress on membrane functions in Escherichia coli: role of HP1 cutalasc. J. Bacteriol. 170:1837-1842.
13. Flint, D. H., J. F. Tuminello, and M. H. Emptage. 1993. The inactivation of Fe-S cluster containing hydro-lyases by superoxide. J. Biol. Chem. 268; 22369-22376.
14. Frei, B., R. Stocker, and B. N. Ames. 1992. Small molecule antioxidant defenses in human extracellular fluids, p. 23-46. In J. G. Scandalios (ed.), Molecular biology of free radical scavenging systems. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. 12 transport in Escherichia coli and homology with components of periplasmic-binding-prolein-dependent transport systems. J. Bacteriol. 167:928-934.
16. Fridovich, I. 1970. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J. Biol. Chem. 245:4053-4057.
17. Fridovich, I. 1978. The biology of oxygen radicals. Science 201:875-880.
18. Gardner, P. R., and I. Fridovich. 1991. Superoxide sensitivity of the Escherichia coli aconitase. J. Biol. Chem. 266:19328-19333.
19. Gonzalez-Flecha, B., and B. Demple. 1995. Metabolic sources of hydrogen peroxide in aerobically growing cells. J. Biol. Chem. 270:13681-13687.
20. Hassan, H. M., and I. Fridovich. 1977. Regulation of the synthesis of superoxide dismutase in Escherichia coli: induction by methyl viologon. J. Biol. Chem. 252:7667-7672.
21. Hassan, H. M., and I. Fridovich. 1978. Superoxide radicals and the oxygen enhancement of the toxicity of paraquat in Escherichia coli. J. Biol. Chem. 253:8143-8148.
22. Hassan, H. M., and I. Fridovich. 1979. Paraquat and Escherichia coli: mechanism of production of extracellular superoxide radical. J. Biol. Chem. 254: 10846-10852.
23. Holland, D., Z. Faltin, A. Perl, G. Ben-Hayyim, and Y. Eshdat. 1994. A novel plant glutathionc peroxidase-like protein provides tolerance to oxygen radicals generated by paraquat in Eschcrichia coli. FEBS Lett. 337:52-55.
24. Imlay, J. A. 1995. A metabolic enzyme that rapidly produces superoxide, fumarate reductase at Escherichia coli. J. Biol. Chem. 270:19767-19777.
25. Imlay, J. A., and I. Fridovich. 1991. Assay of metabolic superoxide production in Escherichia coli. J. Biol. Chem. 266:6957-6965.
26. Imlay, J. A., and S. Linn. 1988. DNA damage and oxygen radical toxicity. Science 240:1302-1309.
27. Jones, R. W., T. A. Gray, and P. B. Garland. 1976. A study of the permeability of the cytoplasmic membrane of Escherichia coli to reduced and oxidized benzyl viologen and methyl viologen cations: complication in the use of viologens as redox mediators for membrane-bound enzymes. Biochem. Soc. Trans. 4:671-673.
28. Keele, B. B., J. M. McCord, and I. Fridovich. 1970. Superoxide dismutase from Escherichia coli B. J. Biol. Chem. 245:6176-6181.
29. Keyer, K., A. S. Gort, and J. A. Imlay. 1995. Superoxide and the production of oxidative DNA damage. J. Bacteriol. 177:6782-6790.
30. Korbashi, P., R. Kohen, J. Katzhendler, and M. Chevion. 1986. Iron mediates paraquat toxicity in Escherichia coli. J. Biol. Chem. 261:12472-12476.
31. Kuo, C. F., T. Mashino, and I. Fridovich. 1987. α,β-Dihydroxyisovalerate dehydratase: a superoxide-sensitive enzyme. J. Biol. Chem. 262:4724-4727.
32. Liochev, S. I., and I. Fridovich. 1992. Fumarase C, the stable fumarase of Escherichia coli. is controlled by the soxRS regulon. Proc. Natl. Acad. Sci. USA 89:5892-5896.
33. 2 in the production of HO · in vitro and in vivo. Free Rad. Biol. Med. 16:29-33.
34. Loewen, P. C., J. Switala, and B. L. Triggs-Raine. 1985. Catalases HPI and HPII in Escherichia coli are induced independently. Arch. Biochem. Biophys. 243:144-149.
35. McCord, J., and I. Fridovich. 1969. Superoxide dismutase. J. Biol. Chem. 244:6049-6055.
36. Moore, T. D. E., and P. F. Sparling. 1995. Isolation and identification of a glutathione peroxidase homolog gene, gpxA. present in Neisseria meningitidis but absent in Neisseria gonorrhoeae. Infect. Immun. 63:1603-1607.
37. Munch, S. 1994. Nonradioactive northern blots in 1.5 days and with substantially increased sensitivity through "alkaline blotting". Biochemica 11:29-31.
38. Prentki, P., and H. M. Krisch. 1984. In vitro insertional mutagenesis with a selectable DNA fragment. Gene 29:303-313.
39. Stortz, G., F. S. Jacobson, L. A. Tartaglia, R. W. Morgan, L. A. Silveira, and B. N. Ames. 1989. An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp. J. Bacteriol. 171:2049-2055.
40. Touati, D., M. Jacques, B. Tardat, L. Bouchard, and S. Depid. 1995. Lethal oxidative damage and mutagenesis are generated by iron in Δfur mutants of Escherichia coli: protective role of superoxide dismutase. J. Bacteriol. 177: 2305-2314.
41. Weitzman, S. A., A. B. Weitberg, E. P. Clark, and T. P. Stossel. 1985. Phagocytes as carcinogens: malignant transformation produced by human neutrophils. Science 227:1231-1233.
42. Yost, F. J. 1973. An iron-containing superoxide dismutase from Escherichia coli. J. Biol. Chem. 248:4905-4908.