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Volumn 37, Issue 4, 1996, Pages 231-248

Preclinical pharmacology of pramlintide in the rat: Comparisons with human and rat amylin

Author keywords

Gastric emptying; Pharmacodynamics; Pharmacokinetics; Rats

Indexed keywords

AMYLIN; GLUCOSE; LACTIC ACID; PRAMLINTIDE;

EID: 8944258562     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199604)37:4<231::AID-DDR5>3.0.CO;2-M     Document Type: Article
Times cited : (128)

References (41)
  • 1
    • 8944242210 scopus 로고
    • Distinct binding sites for calcitonin gene-related peptide (CGRP) and amylin in the porcine nucleus accumbens
    • Aiyar N, Baker E, Martin J, Patel A, Barone F, Stadel J, Willette R (1994): Distinct binding sites for calcitonin gene-related peptide (CGRP) and amylin in the porcine nucleus accumbens. FASEB 8:A832.
    • (1994) FASEB , vol.8
    • Aiyar, N.1    Baker, E.2    Martin, J.3    Patel, A.4    Barone, F.5    Stadel, J.6    Willette, R.7
  • 2
    • 0029165079 scopus 로고
    • Differential calcitonin gene-related peptide (CGRP) and amylin binding sites in nucleus accumbens and lung: Potential models for studying CGRP/amylin receptor subtypes
    • Aiyar N, Baker E, Martin J, Patel A, Stadel JM, Willette RN, Barone FC (1995): Differential calcitonin gene-related peptide (CGRP) and amylin binding sites in nucleus accumbens and lung: Potential models for studying CGRP/amylin receptor subtypes. J Neurochem 65:1131-1138.
    • (1995) J Neurochem , vol.65 , pp. 1131-1138
    • Aiyar, N.1    Baker, E.2    Martin, J.3    Patel, A.4    Stadel, J.M.5    Willette, R.N.6    Barone, F.C.7
  • 5
    • 0024428356 scopus 로고
    • Islet amyloid polypeptide (IAPP)-cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus
    • Betsholtz C, Svensson V, Rorsman F, Engstrom U, Westermark GT, Wilander E, Johnson K, Westermark P (1989): Islet amyloid polypeptide (IAPP)-cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus. Exp Cell Res 183:484-493.
    • (1989) Exp Cell Res , vol.183 , pp. 484-493
    • Betsholtz, C.1    Svensson, V.2    Rorsman, F.3    Engstrom, U.4    Westermark, G.T.5    Wilander, E.6    Johnson, K.7    Westermark, P.8
  • 6
    • 0025264935 scopus 로고
    • The demonstration of vasodilator activity of pancreatic amylin amide in the rabbit
    • Brain SD, Wimalawansa S, MacIntyre I, Williams TJ (1990): The demonstration of vasodilator activity of pancreatic amylin amide in the rabbit. Am J Pathol 136:487-490.
    • (1990) Am J Pathol , vol.136 , pp. 487-490
    • Brain, S.D.1    Wimalawansa, S.2    MacIntyre, I.3    Williams, T.J.4
  • 7
    • 0000807673 scopus 로고
    • The effects of amylin on changes in plasma glucose and gastric emptying following an oral glucose load in conscious dogs
    • Brown K, Menius A, Sandefer E, Edwards J, James M (1994): The effects of amylin on changes in plasma glucose and gastric emptying following an oral glucose load in conscious dogs. Diabetes 43:172A.
    • (1994) Diabetes , vol.43
    • Brown, K.1    Menius, A.2    Sandefer, E.3    Edwards, J.4    James, M.5
  • 8
    • 0028901314 scopus 로고
    • Amylin islet amyloid polypeptide: Biochemistry, physiology, patho-physiology
    • Castillo MJ, Scheen AJ, Lefebvre PJ (1995): Amylin islet amyloid polypeptide: Biochemistry, physiology, patho-physiology. Diabetes Metab 21:3-25.
    • (1995) Diabetes Metab , vol.21 , pp. 3-25
    • Castillo, M.J.1    Scheen, A.J.2    Lefebvre, P.J.3
  • 10
    • 0023579739 scopus 로고
    • Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
    • Cooper GJS, Willis AC, Clark A, Turner RC, Sim RB, Reid KB (1987): Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA 84:8628-8632.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8628-8632
    • Cooper, G.J.S.1    Willis, A.C.2    Clark, A.3    Turner, R.C.4    Sim, R.B.5    Reid, K.B.6
  • 12
    • 0027465772 scopus 로고
    • Amylin inhibits glucose-induced insulin secretion in a dose-dependent manner - Study in the perfused rat pancreas
    • Dégano P, Silvestre RA, Salas M, Peiro E, Marco J (1993): Amylin inhibits glucose-induced insulin secretion in a dose-dependent manner - study in the perfused rat pancreas. Regul Pept 43:91-96.
    • (1993) Regul Pept , vol.43 , pp. 91-96
    • Dégano, P.1    Silvestre, R.A.2    Salas, M.3    Peiro, E.4    Marco, J.5
  • 14
    • 0002678937 scopus 로고
    • The preparation of radioiodinated proteins of high activity, their reaction with antibody in vitro: The radioimmunoassay
    • Weir DM (eds): Philadelphia: FA Davis
    • Hunter WM (1967): The preparation of radioiodinated proteins of high activity, their reaction with antibody in vitro: The radioimmunoassay. In Weir DM (eds): Handbook of Experimental Immunology. Philadelphia: FA Davis,
    • (1967) Handbook of Experimental Immunology
    • Hunter, W.M.1
  • 15
    • 34547383713 scopus 로고
    • Preparation of Iodine-131 labelled human growth hormone of high specific activity
    • Hunter WM, Greenwood FC (1962): Preparation of Iodine-131 labelled human growth hormone of high specific activity. Nature 194:495-496.
    • (1962) Nature , vol.194 , pp. 495-496
    • Hunter, W.M.1    Greenwood, F.C.2
  • 17
    • 8944244033 scopus 로고
    • Administration of tripro-amylin reduces postprandial hyperglycemia in subjects with juvenile-onset diabetes
    • Kolterman OG, Gottlieb AB, Moyses CJ (1994a): Administration of tripro-amylin reduces postprandial hyperglycemia in subjects with juvenile-onset diabetes. Diabetologia 37:A72.
    • (1994) Diabetologia , vol.37
    • Kolterman, O.G.1    Gottlieb, A.B.2    Moyses, C.J.3
  • 18
    • 8544281545 scopus 로고
    • Amylin agonist, AC137, reduces postprandial hyperglycemia in subjects with insulin dependent diabetes mellitus (IDDM)
    • Kolterman O, Gottlieb A, Moyses C (1994b): Amylin agonist, AC137, reduces postprandial hyperglycemia in subjects with insulin dependent diabetes mellitus (IDDM). Diabetes 43:78A.
    • (1994) Diabetes , vol.43
    • Kolterman, O.1    Gottlieb, A.2    Moyses, C.3
  • 19
    • 8944225473 scopus 로고
    • Infusion of amylin agonist AC-0137 reduces postprandial hyperglycemia in subjects with type 1 diabetes
    • Kolterman O, Kisicki JC, Peltier L, Gottlieb A, Moyses C (1994c): Infusion of amylin agonist AC-0137 reduces postprandial hyperglycemia in subjects with type 1 diabetes. Clin Res 42:87A.
    • (1994) Clin Res , vol.42
    • Kolterman, O.1    Kisicki, J.C.2    Peltier, L.3    Gottlieb, A.4    Moyses, C.5
  • 20
    • 8944254217 scopus 로고
    • Reduction of postprandial hyperglycemia in patients with type II diabetes by the human amylin analogue AC137
    • Kolterman OG, Gottlieb AB, Organ KA, Thompson RG (1995a): Reduction of postprandial hyperglycemia in patients with type II diabetes by the human amylin analogue AC137. Diabetologia 38:A193.
    • (1995) Diabetologia , vol.38
    • Kolterman, O.G.1    Gottlieb, A.B.2    Organ, K.A.3    Thompson, R.G.4
  • 21
    • 0029162915 scopus 로고
    • Reduction of postprandial hyperglycemia in subjects with IDDM by intravenous infusion of AC137, a human amylin analogue
    • Kolterman OG, Gottlieb A, Moyses C, Colburn W (1995b): Reduction of postprandial hyperglycemia in subjects with IDDM by intravenous infusion of AC137, a human amylin analogue. Diabetes Care 18:1179-1182.
    • (1995) Diabetes Care , vol.18 , pp. 1179-1182
    • Kolterman, O.G.1    Gottlieb, A.2    Moyses, C.3    Colburn, W.4
  • 22
    • 8944232079 scopus 로고
    • Intravenous infusion of the human amylin analogue, AC 137, reduces postprandial hyperglycemia in subjects with type I diabetes mellitus receiving oral nutrients but not IV glucose
    • Kolterman O, Organ K, Gottlieb A (1995c): Intravenous infusion of the human amylin analogue, AC 137, reduces postprandial hyperglycemia in subjects with type I diabetes mellitus receiving oral nutrients but not IV glucose. Diabetes 44:127A.
    • (1995) Diabetes , vol.44
    • Kolterman, O.1    Organ, K.2    Gottlieb, A.3
  • 23
    • 4243451734 scopus 로고
    • Subcutaneous administration of AC137, a human amylin analogue, reduces postprandial hyperglycemia in subjects with type I diabetes mellitus
    • Kolterman O, Peterson J, Gottlieb A (1995d): Subcutaneous administration of AC137, a human amylin analogue, reduces postprandial hyperglycemia in subjects with type I diabetes mellitus. Diabetes 44:57A.
    • (1995) Diabetes , vol.44
    • Kolterman, O.1    Peterson, J.2    Gottlieb, A.3
  • 24
    • 0023692891 scopus 로고
    • Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro
    • Leighton B, Cooper GJS (1988): Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. Nature 335:632-635.
    • (1988) Nature , vol.335 , pp. 632-635
    • Leighton, B.1    Cooper, G.J.S.2
  • 26
    • 0025737181 scopus 로고
    • Amylin decreases food intake in mice
    • Morley JE, Flood JF (1991): Amylin decreases food intake in mice. Peptides 12:865-869.
    • (1991) Peptides , vol.12 , pp. 865-869
    • Morley, J.E.1    Flood, J.F.2
  • 27
    • 0026784118 scopus 로고
    • Comparison of a calcitonin gene-related peptide receptor in a human neuroblastoma cell line (SK-N-MC) and a calcitonin receptor in a human breast carcinoma cell line (T47D)
    • Muff R, Stangl D, Born W, Fischer JA (1992): Comparison of a calcitonin gene-related peptide receptor in a human neuroblastoma cell line (SK-N-MC) and a calcitonin receptor in a human breast carcinoma cell line (T47D). Ann N Y Acad Sci 657:106-116.
    • (1992) Ann N Y Acad Sci , vol.657 , pp. 106-116
    • Muff, R.1    Stangl, D.2    Born, W.3    Fischer, J.A.4
  • 28
    • 0025262297 scopus 로고
    • Amylin secretion from the rat pancreas and its selective loss after streptozotocin treatment
    • Ogawa A, Harris V, McCorkle SK, Unger RH, Luskey KL (1990): Amylin secretion from the rat pancreas and its selective loss after streptozotocin treatment. J Clin Invest 85:973-976.
    • (1990) J Clin Invest , vol.85 , pp. 973-976
    • Ogawa, A.1    Harris, V.2    McCorkle, S.K.3    Unger, R.H.4    Luskey, K.L.5
  • 29
    • 0029850418 scopus 로고    scopus 로고
    • Development and characterization of monoclonal antibodies specific for amylin
    • submitted
    • Phelps JL, Blase E, Koda JE (1996): Development and characterization of monoclonal antibodies specific for amylin. Hybridoma (submitted).
    • (1996) Hybridoma
    • Phelps, J.L.1    Blase, E.2    Koda, J.E.3
  • 30
    • 0027994014 scopus 로고
    • In vitro autoradiographic localization of amylin binding sites in rat brain
    • Sexton PM, Paxinos G, Kenney MA, Wookey PJ, Beaumont K (1994): In vitro autoradiographic localization of amylin binding sites in rat brain. Neuroscience 62:553-567.
    • (1994) Neuroscience , vol.62 , pp. 553-567
    • Sexton, P.M.1    Paxinos, G.2    Kenney, M.A.3    Wookey, P.J.4    Beaumont, K.5
  • 31
    • 8544254592 scopus 로고
    • The human amylin analogue (AC137) reduces glucose following Sustacal in patients with type II diabetes
    • Thompson RG, Gottlieb AB, Organ K, Kolterman OG (1995): The human amylin analogue (AC137) reduces glucose following Sustacal in patients with type II diabetes. Diabetes 44:127A.
    • (1995) Diabetes , vol.44
    • Thompson, R.G.1    Gottlieb, A.B.2    Organ, K.3    Kolterman, O.G.4
  • 32
    • 0028037694 scopus 로고
    • Autoradiographic distribution and receptor binding profile of [I-125]Bolton Hunter-rat amylin binding sites in the rat brain
    • Van Rossum D, Menard DP, Fournier A, St Pierre S, Quirion R (1994): Autoradiographic distribution and receptor binding profile of [I-125]Bolton Hunter-rat amylin binding sites in the rat brain. J Pharmacol Exp Ther 270:779-787.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 779-787
    • Van Rossum, D.1    Menard, D.P.2    Fournier, A.3    St Pierre, S.4    Quirion, R.5
  • 33
    • 0028800972 scopus 로고
    • Amylin-induced relaxation of the perfused mesenteric arterial bed: Meditation by calcitonin gene-related peptide receptors
    • Westfall TC, Curfman-Falvey M (1995): Amylin-induced relaxation of the perfused mesenteric arterial bed: Meditation by calcitonin gene-related peptide receptors. J Cardiovasc Pharmacol 26:932-936.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 932-936
    • Westfall, T.C.1    Curfman-Falvey, M.2
  • 35
    • 0025800404 scopus 로고
    • Amylin injection causes elevated plasma lactate and glucose in the rat
    • Young AA, Wang MW, Cooper GJS (1991): Amylin injection causes elevated plasma lactate and glucose in the rat. FEBS Lett 291:101-104.
    • (1991) FEBS Lett , vol.291 , pp. 101-104
    • Young, A.A.1    Wang, M.W.2    Cooper, G.J.S.3
  • 37
    • 0027469751 scopus 로고
    • Dose response characteristics for the hyperglycemic, hyperlactemic, hypotensive and hypocalcemic actions of amylin and calcitonin gene-related peptide-I (CGRP-alpha) in the fasted, anaesthetized rat
    • Young AA, Rink TJ, Wang MW (1993): Dose response characteristics for the hyperglycemic, hyperlactemic, hypotensive and hypocalcemic actions of amylin and calcitonin gene-related peptide-I (CGRP-alpha) in the fasted, anaesthetized rat. Life Sci 52:1717-1726.
    • (1993) Life Sci , vol.52 , pp. 1717-1726
    • Young, A.A.1    Rink, T.J.2    Wang, M.W.3
  • 38
    • 0029063901 scopus 로고
    • Gastric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin
    • Young AA, Gedulin B, Vine W, Percy A, Rink TJ (1995a): Gastric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin. Diabetologia 38:642-648.
    • (1995) Diabetologia , vol.38 , pp. 642-648
    • Young, A.A.1    Gedulin, B.2    Vine, W.3    Percy, A.4    Rink, T.J.5
  • 39
    • 3242710848 scopus 로고
    • Inhibition of arginine-induced glucagon secretion by amylin in rats
    • Young AA, Jodka CM, Green DE, Gedulin BR (1995b): Inhibition of arginine-induced glucagon secretion by amylin in rats. Diabetes 44:238A.
    • (1995) Diabetes , vol.44
    • Young, A.A.1    Jodka, C.M.2    Green, D.E.3    Gedulin, B.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.