-
2
-
-
0027399661
-
The effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in NIDDM subjects - A study of two ethnic groups
-
Nagi DK, Yudkin JS. The effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in NIDDM subjects - a study of two ethnic groups. Diabetes Care 1993; 16: 621-629.
-
(1993)
Diabetes Care
, vol.16
, pp. 621-629
-
-
Nagi, D.K.1
Yudkin, J.S.2
-
3
-
-
0022881373
-
Effects of metformin on peripheral insulin sensitivity in non-insulin dependent diabetes mellitus
-
Prager R, Schernthaner C, Graf H. Effects of metformin on peripheral insulin sensitivity in non-insulin dependent diabetes mellitus. Diabete et Metabolisme 1986; 12: 346-350.
-
(1986)
Diabete et Metabolisme
, vol.12
, pp. 346-350
-
-
Prager, R.1
Schernthaner, C.2
Graf, H.3
-
4
-
-
0023275154
-
Effect of metformin on insulin-stimulated glucose turnover and insulin binding to receptors in type II diabetes
-
Nosadini R, Avogaro A, Trevisan R, Valerio A, Tessari P, Duner E, et al. Effect of metformin on insulin-stimulated glucose turnover and insulin binding to receptors in type II diabetes. Diabetes Care 1987; 10: 62-67.
-
(1987)
Diabetes Care
, vol.10
, pp. 62-67
-
-
Nosadini, R.1
Avogaro, A.2
Trevisan, R.3
Valerio, A.4
Tessari, P.5
Duner, E.6
-
5
-
-
0025837055
-
Mechanism of metformin action in obese and lean non-insulin-dependent diabetic subjects
-
DeFronzo RA, Barzilay N, Simonson DC. Mechanism of metformin action in obese and lean non-insulin-dependent diabetic subjects. J Clin Endocrinol Metab 1991; 73: 1294-1301.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 1294-1301
-
-
DeFronzo, R.A.1
Barzilay, N.2
Simonson, D.C.3
-
6
-
-
0017754243
-
Comparison of metformin and chlorpropamide in non-obese maturity onset diabetics uncontrolled by diet
-
Clarke BF, Campbell IW. Comparison of metformin and chlorpropamide in non-obese maturity onset diabetics uncontrolled by diet. Br Med J 1977; 2: 1576-1578.
-
(1977)
Br Med J
, vol.2
, pp. 1576-1578
-
-
Clarke, B.F.1
Campbell, I.W.2
-
7
-
-
0014423575
-
Comparison of chlorpropamide and metformin treatment on weight and blood glucose response of uncontrolled obese diabetics
-
Clarke BF, Duncan LJP. Comparison of chlorpropamide and metformin treatment on weight and blood glucose response of uncontrolled obese diabetics. Lancet 1968; i: 123-126.
-
(1968)
Lancet
, vol.1
, pp. 123-126
-
-
Clarke, B.F.1
Duncan, L.J.P.2
-
8
-
-
0001157421
-
Biguanides: Basic aspects and clinical uses
-
Alberti KGMM, Defronzo RA, Keen HA, Zimmer PA, Eds. Chichester: Wiley
-
Hermann LS, Melander A. Biguanides: basic aspects and clinical uses. In: Alberti KGMM, Defronzo RA, Keen HA, Zimmer PA, Eds. International Textbook of Diabetes Mellitus. Chichester: Wiley 1992: 773-795.
-
(1992)
International Textbook of Diabetes Mellitus
, pp. 773-795
-
-
Hermann, L.S.1
Melander, A.2
-
9
-
-
0024493106
-
Effects of dietary treatment on serum insulin and proinsulin response in newly diagnosed NIDDM
-
Yoshioka N, Kazuya T, Matsuda A, Iwamoto Y. Effects of dietary treatment on serum insulin and proinsulin response in newly diagnosed NIDDM. Diabetes 1989; 38: 262-267.
-
(1989)
Diabetes
, vol.38
, pp. 262-267
-
-
Yoshioka, N.1
Kazuya, T.2
Matsuda, A.3
Iwamoto, Y.4
-
10
-
-
0023634652
-
Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin dependent) diabetes mellitus and in experimental insulin resistance
-
Ward WK, LaCava EC, Paquette TL, Beard JC, Wallum BJ, Porte D. Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin dependent) diabetes mellitus and in experimental insulin resistance. Diabetologia 1987; 30: 698-702.
-
(1987)
Diabetologia
, vol.30
, pp. 698-702
-
-
Ward, W.K.1
LaCava, E.C.2
Paquette, T.L.3
Beard, J.C.4
Wallum, B.J.5
Porte, D.6
-
11
-
-
0025036044
-
The relationship between concentrations of insulin, intact proinsulin, and 32-33 split proinsulin and cardiovascular risk factors in type 2 (non-insulin-dependent) diabetic subjects
-
Nagi DK, Hendra TJ, Ryle AJ, Cooper TM, Temple RC, Clark PMS, et al. The relationship between concentrations of insulin, intact proinsulin, and 32-33 split proinsulin and cardiovascular risk factors in type 2 (non-insulin-dependent) diabetic subjects. Diabetologia 1990; 33: 532-537.
-
(1990)
Diabetologia
, vol.33
, pp. 532-537
-
-
Nagi, D.K.1
Hendra, T.J.2
Ryle, A.J.3
Cooper, T.M.4
Temple, R.C.5
Clark, P.M.S.6
-
12
-
-
0027389774
-
Increased proinsulin/insulin ratio in pancreas extracts of hyperglycemic rats
-
Leahy JL. Increased proinsulin/insulin ratio in pancreas extracts of hyperglycemic rats. Diabetes 1993; 42: 22-27.
-
(1993)
Diabetes
, vol.42
, pp. 22-27
-
-
Leahy, J.L.1
-
13
-
-
0025736943
-
Relative hypersecretion of proinsulin in rat model of NIDDM
-
Leahy JL, Halban PA, Weir GC. Relative hypersecretion of proinsulin in rat model of NIDDM. Diabetes 1991; 40: 985-989.
-
(1991)
Diabetes
, vol.40
, pp. 985-989
-
-
Leahy, J.L.1
Halban, P.A.2
Weir, G.C.3
-
14
-
-
0027251601
-
Insulin deficiency rather than hyperinsulinaemia in newly diagnosed type 2 diabetes mellitus
-
Davies MJ, Metcalf J, Gray IP, Day JL, Hales CN. Insulin deficiency rather than hyperinsulinaemia in newly diagnosed type 2 diabetes mellitus. Diabetic Med 1993; 10: 305-312.
-
(1993)
Diabetic Med
, vol.10
, pp. 305-312
-
-
Davies, M.J.1
Metcalf, J.2
Gray, I.P.3
Day, J.L.4
Hales, C.N.5
-
15
-
-
8944253336
-
The relationship between insulin, intact proinsulin, des 31,32 proinsulin and other cardiovascular risk factors in non-diabetic subjects
-
Mohamed-Ali V, Gould M, Goubet S, Yudkin JS. The relationship between insulin, intact proinsulin, des 31,32 proinsulin and other cardiovascular risk factors in non-diabetic subjects. Diabetic Med 1993; 10 (suppl 2): P54.
-
(1993)
Diabetic Med
, vol.10
, Issue.2 SUPPL.
-
-
Mohamed-Ali, V.1
Gould, M.2
Goubet, S.3
Yudkin, J.S.4
-
16
-
-
0027282072
-
The relationship of proinsulin and insulin to cardiovascular risk factors in non-diabetic subjects
-
Haffner SM, Mykkanen L, Stern MP, Valdez RA, Heisserman JA, Bowsher RR. The relationship of proinsulin and insulin to cardiovascular risk factors in non-diabetic subjects. Diabetes 1993; 42: 1297-1302.
-
(1993)
Diabetes
, vol.42
, pp. 1297-1302
-
-
Haffner, S.M.1
Mykkanen, L.2
Stern, M.P.3
Valdez, R.A.4
Heisserman, J.A.5
Bowsher, R.R.6
-
17
-
-
0024340494
-
Sensitive and specific two-site immunoradiometric assays to human insulin, proinsulin, 65-66 split and 32-33 split proinsulin
-
Sobey WJ, Beer SF, Carrington CA, Clark PMS, Frank BH, Gray P, et al. Sensitive and specific two-site immunoradiometric assays to human insulin, proinsulin, 65-66 split and 32-33 split proinsulin. Biochem J 1989: 260; 535-541.
-
(1989)
Biochem J
, vol.260
, pp. 535-541
-
-
Sobey, W.J.1
Beer, S.F.2
Carrington, C.A.3
Clark, P.M.S.4
Frank, B.H.5
Gray, P.6
-
18
-
-
0344568445
-
An end-point amplified enzymoimmunoassay (IEMA) specific for human insulin
-
Mohamed-Ali V, Yudkin JS. An end-point amplified enzymoimmunoassay (IEMA) specific for human insulin. Clin Sci 1992; 82 (suppl 27) P4.
-
(1992)
Clin Sci
, vol.82
, Issue.27 SUPPL.
-
-
Mohamed-Ali, V.1
Yudkin, J.S.2
-
19
-
-
7844239519
-
Simple and highly sensitive microplate assays (IRMAs) for intact proinsulin and des 31,32 proinsulin
-
Mohamed-Ali V, Yudkin JS. Simple and highly sensitive microplate assays (IRMAs) for intact proinsulin and des 31,32 proinsulin. Diabetic Med 1993; 10 (suppl 1) P67.
-
(1993)
Diabetic Med
, vol.10
, Issue.1 SUPPL.
-
-
Mohamed-Ali, V.1
Yudkin, J.S.2
-
20
-
-
0021053614
-
Evidence of a rapid inhibitor to tissue plasminogen activators in plasma
-
Chmieiewska J, Ranby M, Wiman B. Evidence of a rapid inhibitor to tissue plasminogen activators in plasma. Thromb Res 1983; 31: 427-436.
-
(1983)
Thromb Res
, vol.31
, pp. 427-436
-
-
Chmieiewska, J.1
Ranby, M.2
Wiman, B.3
-
21
-
-
0024494876
-
Insulin deficiency in non-insulin-dependent diabetes
-
Temple RC, Carrington CA, Luzio SD, Owens DR, Schneider AE, Sobey WJ, et al. Insulin deficiency in non-insulin-dependent diabetes. Lancet 1989; i: 293-295.
-
(1989)
Lancet
, vol.1
, pp. 293-295
-
-
Temple, R.C.1
Carrington, C.A.2
Luzio, S.D.3
Owens, D.R.4
Schneider, A.E.5
Sobey, W.J.6
-
22
-
-
0025268864
-
Disproportionately elevated proinsulin in Pima Indians with non-insulin dependent diabetes mellitus
-
Saad MF, Kahn SE, Nelson RG, Pettitt DJ, Knowler WC, Schwartz MW, et al. Disproportionately elevated proinsulin in Pima Indians with non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab 1990; 70: 1247-1253.
-
(1990)
J Clin Endocrinol Metab
, vol.70
, pp. 1247-1253
-
-
Saad, M.F.1
Kahn, S.E.2
Nelson, R.G.3
Pettitt, D.J.4
Knowler, W.C.5
Schwartz, M.W.6
-
23
-
-
0028137716
-
Improved Beta cell function, with reduction in secretion of intact and 32,33 split proninsulin, after dietary intervention in subjects with Type 2 diabetes mellitus
-
Davies MJ, Metcalf J, Day JL, Grenfell A, Hales CN, Gray IP. Improved Beta cell function, with reduction in secretion of intact and 32,33 split proninsulin, after dietary intervention in subjects with Type 2 diabetes mellitus. Diabetic Med 1994; 11: 71-78.
-
(1994)
Diabetic Med
, vol.11
, pp. 71-78
-
-
Davies, M.J.1
Metcalf, J.2
Day, J.L.3
Grenfell, A.4
Hales, C.N.5
Gray, I.P.6
-
24
-
-
0019995911
-
The long-term effects of chlorpropamide on insulin, C-peptide, and proinsulin secretion
-
Elkeles RS, Heding LG, Paisey RB. The long-term effects of chlorpropamide on insulin, C-peptide, and proinsulin secretion. Diabetes Care 1982; 5: 427-429.
-
(1982)
Diabetes Care
, vol.5
, pp. 427-429
-
-
Elkeles, R.S.1
Heding, L.G.2
Paisey, R.B.3
-
25
-
-
0015413087
-
Effect of chronic sulphonylurea therapy on plasma insulin and proinsulin levels
-
Duckworth WC, Solomon S, Kitabchi AE. Effect of chronic sulphonylurea therapy on plasma insulin and proinsulin levels. J Clin Endocrinol Metab 1974; 35: 585-591.
-
(1974)
J Clin Endocrinol Metab
, vol.35
, pp. 585-591
-
-
Duckworth, W.C.1
Solomon, S.2
Kitabchi, A.E.3
-
26
-
-
0028314832
-
Effect of sulphonylurea therapy on plasma insulin, intact proinsulin, and 32,33 split proinsulin in subjects with Type 2 diabetes mellitus
-
Davies MJ, Metcalf J, Day JL, Grenfell A, Gray IP, Hales CN. Effect of sulphonylurea therapy on plasma insulin, intact proinsulin, and 32,33 split proinsulin in subjects with Type 2 diabetes mellitus. Diabetic Med 1994; 11: 293-298.
-
(1994)
Diabetic Med
, vol.11
, pp. 293-298
-
-
Davies, M.J.1
Metcalf, J.2
Day, J.L.3
Grenfell, A.4
Gray, I.P.5
Hales, C.N.6
-
27
-
-
0028204065
-
Understanding oral glucose tolerance: Comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion
-
Phillips DIW, Clark PM, Hales CN, Osmond C. Understanding oral glucose tolerance: Comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion. Diabetic Med 1994; 11: 286-292.
-
(1994)
Diabetic Med
, vol.11
, pp. 286-292
-
-
Phillips, D.I.W.1
Clark, P.M.2
Hales, C.N.3
Osmond, C.4
-
28
-
-
8944244562
-
Proinsulin-like molecules relate to insulin resistance in non-insulin-dependent diabetes
-
Panahloo A, Mohamed-Ali V, Denver E, Andres C, Yudkin JS. Proinsulin-like molecules relate to insulin resistance in non-insulin-dependent diabetes. Diabetic Med 1994; 11 (suppl 2): A24.
-
(1994)
Diabetic Med
, vol.11
, Issue.2 SUPPL.
-
-
Panahloo, A.1
Mohamed-Ali, V.2
Denver, E.3
Andres, C.4
Yudkin, J.S.5
-
29
-
-
0026239966
-
The enzymology of proinsulin conversion
-
Hutton JC, Rhodes CJ. The enzymology of proinsulin conversion. Cell Biophysics 1991; 19: 57-62.
-
(1991)
Cell Biophysics
, vol.19
, pp. 57-62
-
-
Hutton, J.C.1
Rhodes, C.J.2
-
30
-
-
0023217851
-
Daily insulin dose as a predictor of macrovascular disease in insulin treated non-insulin-dependent diabetics
-
Janka HU, Ziegler AG, Standl E, Mehnert H. Daily insulin dose as a predictor of macrovascular disease in insulin treated non-insulin-dependent diabetics. Diabete & Metabolisme 1987; 13: 359-364.
-
(1987)
Diabete & Metabolisme
, vol.13
, pp. 359-364
-
-
Janka, H.U.1
Ziegler, A.G.2
Standl, E.3
Mehnert, H.4
-
31
-
-
0022331714
-
High serum insulin concentrations in relation to other cardiovascular risk factors in macrovas-cular disease of Type 2 diabetes
-
Standl E, Janka HU. High serum insulin concentrations in relation to other cardiovascular risk factors in macrovas-cular disease of Type 2 diabetes. Horm Metab Res 1985; 15: 46-51.
-
(1985)
Horm Metab Res
, vol.15
, pp. 46-51
-
-
Standl, E.1
Janka, H.U.2
|