Production of a recombinant human monoclonal antibody using a novel hollow fiber bioreactor system

Journal of Fermentation and Bioengineering

Volumn 81, Issue 5, 1996, Pages 466-469

  Inoue, Yuichi ^a   Kawamoto, Seiji ^a   Seki, Kiyohiko ^b   Teruya, Kiichiro ^a   Mochizuki, Katsumi ^c   Kato, Masatoshi ^c   Hashizume, Shuichi ^c   Yasumoto, Kosei ^d   Nagashima, Akira ^e   Nakahashi, Hisashi ^f   Suzuki, Tatsuo ^g   Imai, Tadaaki ^h   Nomoto, Kikuo ^a   Shirahata, Sanetaka ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

^c 2 1 1 Shimosueyoshi   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^e KITAKYUSHU MUNICIPAL MEDICAL CENTER   (Japan)

^f MATSUYAMA RED CROSS HOSPITAL   (Japan)

^g KITASATO INSTITUTE HOSPITAL   (Japan)

^h KITASATO UNIVERSITY MEDICAL CENTER   (Japan)

Author keywords

BHK 21 cells; high density culture; hollow fiber bioreactor; ras oncogene; recombinant human monoclonal antibody

Indexed keywords

HUMAN MONOCLONAL ANTIBODY;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BIOREACTOR; CELL CULTURE; DISEASE CONTROL; FERMENTATION; GENE AMPLIFICATION; GENE EXPRESSION; LUNG CANCER; ONCOGENE RAS;

EID: 8944246326     PISSN: 0922338X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0922-338X(96)85150-6     Document Type: Article

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