-
1
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki, E., M. A. Lipes, M. E. Patti, J. C. Bruning, B. Haag III, R. S. Johnson, and C. R. Kahn. 1994. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature (London) 372:186-190.
-
(1994)
Nature (London)
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag III, B.5
Johnson, R.S.6
Kahn, C.R.7
-
2
-
-
0026660653
-
The phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation
-
Backer, J. M., M. G. Myers, Jr., S. E. Shoelson, D. J. Chin, X. J. Sun, M. Miralpeix, P. Hu, B. Margolis, E. Y. Skolnik, J. Schlessinger, and M. F. White. 1992. The phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO J. 11:3469-3479.
-
(1992)
EMBO J
, vol.11
, pp. 3469-3479
-
-
Backer, J.M.1
Myers Jr., M.G.2
Shoelson, S.E.3
Chin, D.J.4
Sun, X.J.5
Miralpeix, M.6
Hu, P.7
Margolis, B.8
Skolnik, E.Y.9
Schlessinger, J.10
White, M.F.11
-
3
-
-
0027450410
-
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity
-
Carpenter, C. L., K. R. Auger, B. C. Duckworth, W.-M. Hou, B. Schaffhausen, and L. C. Cantley. 1993. A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol. Cell. Biol. 13:1657-1665.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1657-1665
-
-
Carpenter, C.L.1
Auger, K.R.2
Duckworth, B.C.3
Hou, W.-M.4
Schaffhausen, B.5
Cantley, L.C.6
-
4
-
-
0028308412
-
Phosphatidylinositol 3′-kinase activation is required for insulin stimulation of pp70 S6 kinase DNA synthesis and glucose transporter translocation
-
Cheatham, R. B., C. J. Vlahos, L. Cheatham, L. Wang, J. Blenis, and C. R. Kahn. 1994. Phosphatidylinositol 3′-kinase activation is required for insulin stimulation of pp70 S6 kinase DNA synthesis and glucose transporter translocation. Mol. Cell. Biol. 14:4902-4911.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, R.B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
5
-
-
0027361017
-
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase
-
Chen, R. H., C. Abate, and J. Blenis. 1993. Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase. Proc. Natl. Acad. Sci. USA 90:10952-10956.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10952-10956
-
-
Chen, R.H.1
Abate, C.2
Blenis, J.3
-
6
-
-
0028178928
-
PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
-
Chung, J., T. C. Grammer, K. P. Lemon, A. Kazlauskas, and J. Blenis. 1994. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature (London) 370:71-75.
-
(1994)
Nature (London)
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammer, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
7
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinase
-
Chung, J., C. J. Kuo, G. R. Crabtree, and J. Blenis. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinase. Cell 69:1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
8
-
-
0027953284
-
PI-3-kinase is a dual specificity enzyme - Autoregulation by an intrinsic protein-serine kinase activity
-
Dhand, R., I. Hiles, G. Panayotou, S. Roche, M. J. Fry, I. Gout, N. F. Totty, O. Truong, P. Vicendo, K. Yonezawa, M. Kasuga, S. A. Courtneidge, and M. D. Waterfield. 1994. PI-3-kinase is a dual specificity enzyme - autoregulation by an intrinsic protein-serine kinase activity. EMBO J. 13:522-533.
-
(1994)
EMBO J
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
Kasuga, M.11
Courtneidge, S.A.12
Waterfield, M.D.13
-
9
-
-
0026085468
-
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine
-
Escobedo, J. A., D. R. Kaplan, W. M. Kavanaugh, C. W. Turck, and L. T. Williams. 1991. A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine. Mol. Cell. Biol. 11:1125-1132.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1125-1132
-
-
Escobedo, J.A.1
Kaplan, D.R.2
Kavanaugh, W.M.3
Turck, C.W.4
Williams, L.T.5
-
10
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signalling pathways
-
Fantl, W. J., J. A. Escobedo, G. A. Martin, C. W. Turck, M. del Rosario, F. McCormick, and L. T. Williams. 1992. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signalling pathways. Cell 69:413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
Del Rosario, M.5
McCormick, F.6
Williams, L.T.7
-
11
-
-
0027536041
-
Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes
-
Fingar, D. C., S. F. Hausdorff, J. Blenis, and M. J. Birnbaum. 1993. Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes. J. Biol. Chem. 268:3005-3008.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 3005-3008
-
-
Fingar, D.C.1
Hausdorff, S.F.2
Blenis, J.3
Birnbaum, M.J.4
-
12
-
-
0026720350
-
Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
-
Hiles, I. D., M. Otsu, S. Volinna, M. J. Fry, I. Gout, R. Dhand, G. Panayotou, F. Ruiz-Larrea, A. Thompson, N. F. Totty, J. J. Hsuan, S. A. Courtneidge, P. J. Parker, and M. D. Waterfield. 1992. Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 70:419-429.
-
(1992)
Cell
, vol.70
, pp. 419-429
-
-
Hiles, I.D.1
Otsu, M.2
Volinna, S.3
Fry, M.J.4
Gout, I.5
Dhand, R.6
Panayotou, G.7
Ruiz-Larrea, F.8
Thompson, A.9
Totty, N.F.10
Hsuan, J.J.11
Courtneidge, S.A.12
Parker, P.J.13
Waterfield, M.D.14
-
13
-
-
0028351218
-
Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites
-
Joly, M., A. Kazlauskas, F. S. Fay, and S. Corvera. 1994. Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science 263:684-687.
-
(1994)
Science
, vol.263
, pp. 684-687
-
-
Joly, M.1
Kazlauskas, A.2
Fay, F.S.3
Corvera, S.4
-
14
-
-
0028486018
-
Phosphatidylinositol 3-kinase
-
Kapeller, R., and L. C. Cantley, Jr. 1994. Phosphatidylinositol 3-kinase. Bio. Essays 16:565-576.
-
(1994)
Bio. Essays
, vol.16
, pp. 565-576
-
-
Kapeller, R.1
Cantley Jr., L.C.2
-
15
-
-
0025765803
-
SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
-
Koch, C. A., D. J. Anderson, M. F. Moran, C. A. Ellis, and T. Pawson. 1991. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 252:668-674.
-
(1991)
Science
, vol.252
, pp. 668-674
-
-
Koch, C.A.1
Anderson, D.J.2
Moran, M.F.3
Ellis, C.A.4
Pawson, T.5
-
16
-
-
0028055272
-
Regulation of chemotaxis by the platelet-derived growth factor receptor-beta
-
Kundra, V., J. A. Escobedo, A. Kazlauskas, H. K. Kim, S. G. Rhee, L. T. Williams, and B. R. Zetter. 1994. Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature (London) 367:474-476.
-
(1994)
Nature (London)
, vol.367
, pp. 474-476
-
-
Kundra, V.1
Escobedo, J.A.2
Kazlauskas, A.3
Kim, H.K.4
Rhee, S.G.5
Williams, L.T.6
Zetter, B.R.7
-
17
-
-
0028018858
-
The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1
-
Lam, K., C. L. Carpenter, N. B. Ruderman, J. C. Friel, and K. L. Kelly. 1994. The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. J. Biol. Chem. 269:20648-20652.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20648-20652
-
-
Lam, K.1
Carpenter, C.L.2
Ruderman, N.B.3
Friel, J.C.4
Kelly, K.L.5
-
18
-
-
0026655777
-
Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in FAO hepatoma cells
-
Miralpeix, M., X. J. Sun, J. M. Backer, M. G. Myers, Jr., E. Araki, and M. F. White. 1992. Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in FAO hepatoma cells. Biochemistry 31:9031-9039.
-
(1992)
Biochemistry
, vol.31
, pp. 9031-9039
-
-
Miralpeix, M.1
Sun, X.J.2
Backer, J.M.3
Myers Jr., M.G.4
Araki, E.5
White, M.F.6
-
19
-
-
0026489451
-
IRS-1 activates the phosphatidylinositol 3′-kinase by associating with the src homology 2 domains of p85
-
Myers, M. G., Jr., J. M. Backer, X. J. Sun, S. E. Shoelson, P. Hu, J. Schlessinger, M. Yoakim, B. Schaffhausen, and M. F. White. 1992. IRS-1 activates the phosphatidylinositol 3′-kinase by associating with the src homology 2 domains of p85. Proc. Natl. Acad. Sci. USA 89:10350-10354.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10350-10354
-
-
Myers Jr., M.G.1
Backer, J.M.2
Sun, X.J.3
Shoelson, S.E.4
Hu, P.5
Schlessinger, J.6
Yoakim, M.7
Schaffhausen, B.8
White, M.F.9
-
20
-
-
0029020217
-
The pleckstrin homology domain in IRS-1 sensitizes insulin signaling
-
Myers, M. G., Jr., T. C. Grammer, J. Brooks, E. M. Glasheen, L. M. Wang, X. J. Sun, J. Blenis, J. H. Pierce, and M. F. White. 1995. The pleckstrin homology domain in IRS-1 sensitizes insulin signaling. J. Biol. Chem. 270: 11715-11718.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11715-11718
-
-
Myers Jr., M.G.1
Grammer, T.C.2
Brooks, J.3
Glasheen, E.M.4
Wang, L.M.5
Sun, X.J.6
Blenis, J.7
Pierce, J.H.8
White, M.F.9
-
21
-
-
0028036698
-
s6k signaling during insulin, IGF-1 and IL-4 stimulation
-
s6k signaling during insulin, IGF-1 and IL-4 stimulation. J. Biol. Chem. 269: 28783-28789.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28783-28789
-
-
Myers Jr., M.G.1
Grammer, T.C.2
Wang, L.M.3
Sun, X.J.4
Pierce, J.H.5
Blenis, J.6
White, M.F.7
-
23
-
-
0028352043
-
Role of IRS-1-GRB-2 complexes in insulin signaling
-
Myers, M. G., Jr., L.-M. Wang, X. J. Sun, Y. Zhang, L. Yenush, J. Schlessinger, J. H. Pierce, and M. F. White. 1994. Role of IRS-1-GRB-2 complexes in insulin signaling. Mol. Cell. Biol. 14:3577-3587.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3577-3587
-
-
Myers Jr., M.G.1
Wang, L.-M.2
Sun, X.J.3
Zhang, Y.4
Yenush, L.5
Schlessinger, J.6
Pierce, J.H.7
White, M.F.8
-
24
-
-
0027212268
-
The new elements in insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains
-
Myers, M. G., Jr., and M. F. White. 1993. The new elements in insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650.
-
(1993)
Diabetes
, vol.42
, pp. 643-650
-
-
Myers Jr., M.G.1
White, M.F.2
-
25
-
-
0029135003
-
New frontiers in insulin receptor substrate signaling
-
Myers, M. G., Jr., and M. F. White. 1995. New frontiers in insulin receptor substrate signaling. Trends Endocrinol. Metab. 6:209-215.
-
(1995)
Trends Endocrinol. Metab.
, vol.6
, pp. 209-215
-
-
Myers Jr., M.G.1
White, M.F.2
-
29
-
-
0025755422
-
c-src complexes and P13-kinase
-
c-src complexes and P13-kinase. Cell 65:91-104.
-
(1991)
Cell
, vol.65
, pp. 91-104
-
-
Otsu, M.1
Hiles, I.2
Gout, I.3
Fry, M.J.4
Ruis-Larrea, F.5
Panayotou, G.6
Thompson, A.7
Dhand, R.8
Hsuan, J.9
Totty, N.10
Smith, A.D.11
Morgan, S.J.12
Courtneidge, S.A.13
Parker, P.J.14
Waterfield, M.D.15
-
30
-
-
0028854920
-
Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains
-
Pluskey, S., T. J. Wandless, C. T. Walsh, and S. E. Shoelson. 1995. Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains. J. Biol. Chem. 270:2897-2900.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2897-2900
-
-
Pluskey, S.1
Wandless, T.J.2
Walsh, C.T.3
Shoelson, S.E.4
-
31
-
-
0028982198
-
PIK reveal a new regulatory subunit for phosphatidylinositol 3- Kinase
-
PIK reveal a new regulatory subunit for phosphatidylinositol 3- kinase. Mol. Cell. Biol. 15:4453-4465.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4453-4465
-
-
Pons, S.1
Asano, T.2
Glasheen, E.3
Miralpeix, M.4
Zhang, Y.5
Fisher, T.L.6
Myers Jr., M.G.7
Sun, X.J.8
White, M.F.9
-
32
-
-
0027466903
-
Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins
-
Pronk, G. J., J. McGlade, G. Pelicci, T. Pawson, and J. L. Bos. 1993. Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins. J. Biol. Chem. 268:5748-5753.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5748-5753
-
-
Pronk, G.J.1
McGlade, J.2
Pelicci, G.3
Pawson, T.4
Bos, J.L.5
-
33
-
-
0028892253
-
Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins
-
Rameh, L. E., C. S. Chen, and L. C. Cantley. 1995. Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins. Cell 83:821-830.
-
(1995)
Cell
, vol.83
, pp. 821-830
-
-
Rameh, L.E.1
Chen, C.S.2
Cantley, L.C.3
-
34
-
-
0028909206
-
Regulation of phosphatidylinositol 3-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85 kDa regulatory subunit
-
Rordorf-Nikolic, T., D. J. Van Horn, D. Chen, M. F. White, and J. M. Backer. 1995. Regulation of phosphatidylinositol 3-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85 kDa regulatory subunit. J. Biol. Chem. 270:3662-3666.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3662-3666
-
-
Rordorf-Nikolic, T.1
Van Horn, D.J.2
Chen, D.3
White, M.F.4
Backer, J.M.5
-
35
-
-
0023188325
-
After insulin binds
-
Rosen, O. M. 1987. After insulin binds. Science 237:1452-1458.
-
(1987)
Science
, vol.237
, pp. 1452-1458
-
-
Rosen, O.M.1
-
36
-
-
0025020250
-
Activation of phosphatidylinositol-3-kinase by insulin
-
Ruderman, N., R. Kapeller, M. F. White, and L. C. Cantley. 1990. Activation of phosphatidylinositol-3-kinase by insulin. Proc. Natl. Acad. Sci. USA 87: 1411-1415.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1411-1415
-
-
Ruderman, N.1
Kapeller, R.2
White, M.F.3
Cantley, L.C.4
-
37
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu, P. V., T. Kaoru, M. J. Fry, J. H. Stack, M. D. Waterfield, and S. D. Emr. 1993. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260:88-91.
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Kaoru, T.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
40
-
-
0027288587
-
The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS-1 and Shc: Implications for insulin control of ras signalling
-
Skolnik, E. Y., C. H. Lee, A. G. Batzer, L. M. Vicentini, M. Zhou, R. J. Daly, M. G. Myers, Jr., J. M. Backer, A. Ullrich, M. F. White, and J. Schlessinger. 1993. The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS-1 and Shc: implications for insulin control of ras signalling. EMBO J. 12:1929-1936.
-
(1993)
EMBO J
, vol.12
, pp. 1929-1936
-
-
Skolnik, E.Y.1
Lee, C.H.2
Batzer, A.G.3
Vicentini, L.M.4
Zhou, M.5
Daly, R.J.6
Myers Jr., M.G.7
Backer, J.M.8
Ullrich, A.9
White, M.F.10
Schlessinger, J.11
-
41
-
-
0027403027
-
SH2 domains recognized specific phosphopeptide sequences
-
Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Roberts, S. Ratnofsky, R. J. Lechleider, B. G. Neel, R. B. Birge, J. E. Fajardo, M. M. Chou, H. Hanafusa, B. Schaffhausen, and J. C. Cantley. 1993. SH2 domains recognized specific phosphopeptide sequences. Cell 72:767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Roberts, T.5
Ratnofsky, S.6
Lechleider, R.J.7
Neel, B.G.8
Birge, R.B.9
Fajardo, J.E.10
Chou, M.M.11
Hanafusa, H.12
Schaffhausen, B.13
Cantley, J.C.14
-
42
-
-
0028282967
-
Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1
-
Sugimoto, S., T. J. Wandless, S. E. Shoelson, B. G. Neel, and C. T. Walsh. 1994. Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1. J. Biol. Chem. 269:13614-13622.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13614-13622
-
-
Sugimoto, S.1
Wandless, T.J.2
Shoelson, S.E.3
Neel, B.G.4
Walsh, C.T.5
-
43
-
-
0027437376
-
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
-
Sun, X. J., D. L. Crimmins, M. G. Myers, Jr., M. Miralpeix, and M. F. White. 1993. Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol. Cell. Biol. 13:7418-7428.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7418-7428
-
-
Sun, X.J.1
Crimmins, D.L.2
Myers Jr., M.G.3
Miralpeix, M.4
White, M.F.5
-
44
-
-
0026595373
-
The expression and function of IRS-1 in insulin signal transmission
-
Sun, X. J., M. Miralpeix, M. G. Myers, Jr., E. M. Glasheen, J. M. Backer, C. R. Kahn, and M. F. White. 1992. The expression and function of IRS-1 in insulin signal transmission. J. Biol. Chem. 267:22662-22672.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22662-22672
-
-
Sun, X.J.1
Miralpeix, M.2
Myers Jr., M.G.3
Glasheen, E.M.4
Backer, J.M.5
Kahn, C.R.6
White, M.F.7
-
45
-
-
15844409347
-
The fyn tyrosine kinase binds IRS-1 and forms a distinct signaling complex during insulin stimulation
-
Sun, X. J., S. Pons, T. Asano, M. G. Myers, Jr., E. Glasheen, and M. F. White. 1996. The fyn tyrosine kinase binds IRS-1 and forms a distinct signaling complex during insulin stimulation. J. Biol. Chem. 271:10583-10587.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10583-10587
-
-
Sun, X.J.1
Pons, S.2
Asano, T.3
Myers Jr., M.G.4
Glasheen, E.5
White, M.F.6
-
46
-
-
0025813375
-
The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun, X. J., P. Rothenberg, C. R. Kahn, J. M. Backer, E. Araki, P. A. Wilden, D. A. Cahill, B. J. Goldstein, and M. F. White. 1991. The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature (London) 352:73-77.
-
(1991)
Nature (London)
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
47
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
Sun, X. J., L. M. Wang, Y. Zhang, L. P. Yenush, M. G. Myers, Jr., E. Glasheen, W. S. Lane, J. H. Pierce, and M. F. White. 1995. Role of IRS-2 in insulin and cytokine signalling. Nature (London) 377:173-177.
-
(1995)
Nature (London)
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.M.2
Zhang, Y.3
Yenush, L.P.4
Myers Jr., M.G.5
Glasheen, E.6
Lane, W.S.7
Pierce, J.H.8
White, M.F.9
-
48
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto, H., T. Kadowaki, K. Tobe, T. Yagi, H. Sakura, T. Hayakawa, Y. Terauchi, K. Ueki, Y. Kaburagi, S. Satoh, H. Sekihara, S. Yoshioka, H. Horikoshi, Y. Furuta, Y. Ikawa, M. Kasuga, Y. Yazaki, and S. Aizawa. 1994. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature (London) 372:182-186.
-
(1994)
Nature (London)
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
Sekihara, H.11
Yoshioka, S.12
Horikoshi, H.13
Furuta, Y.14
Ikawa, Y.15
Kasuga, M.16
Yazaki, Y.17
Aizawa, S.18
-
49
-
-
0028560447
-
3
-
3. J. Biol. Chem. 269:32358-32367.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32358-32367
-
-
Toker, A.1
Meyer, M.2
Reddy, K.3
Falck, J.R.4
Aneja, R.5
Aneja, S.6
Parra, A.7
Burns, D.J.8
Dallas, L.M.9
Cantley Jr., L.C.10
-
50
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
51
-
-
0028928447
-
Insulin-dependent tyrosine phosphorylation of the vav proto-oncogene product in cells of hematopoietic origin
-
Uddin, S., S. Katzav, M. F. White, and L. C. Platanias. 1995. Insulin-dependent tyrosine phosphorylation of the vav proto-oncogene product in cells of hematopoietic origin. J. Biol. Chem. 270:7712-7716.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7712-7716
-
-
Uddin, S.1
Katzav, S.2
White, M.F.3
Platanias, L.C.4
-
52
-
-
0028982917
-
Interferon-alpha engages IRS-signaling proteins to regulate the phosphatidylinositol 3-kinase
-
Uddin, S., L. P. Yenush, X. J. Sun, M. E. Sweet, M. F. White, and L. C. Platanias. 1995. Interferon-alpha engages IRS-signaling proteins to regulate the phosphatidylinositol 3-kinase. J. Biol. Chem. 270:15938-15941.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15938-15941
-
-
Uddin, S.1
Yenush, L.P.2
Sun, X.J.3
Sweet, M.E.4
White, M.F.5
Platanias, L.C.6
-
53
-
-
0027507755
-
IRS-1: Essential for insulin and IL-4-stimulated mitogenesis in hematopoietic cells
-
Wang, L. M., M. G. Myers, Jr., X. J. Sun, S. A. Aaronson, M. F. White, and J. H. Pierce. 1993. IRS-1: essential for insulin and IL-4-stimulated mitogenesis in hematopoietic cells. Science 261:1591-1594.
-
(1993)
Science
, vol.261
, pp. 1591-1594
-
-
Wang, L.M.1
Myers Jr., M.G.2
Sun, X.J.3
Aaronson, S.A.4
White, M.F.5
Pierce, J.H.6
-
54
-
-
0026005158
-
Preparation and use of antiphosphotyrosinc antibodies to study structure and function of insulin receptors
-
White, M. F., and J. M. Backer. 1991. Preparation and use of antiphosphotyrosinc antibodies to study structure and function of insulin receptors. Methods Enzymol. 201:65-79.
-
(1991)
Methods Enzymol
, vol.201
, pp. 65-79
-
-
White, M.F.1
Backer, J.M.2
-
55
-
-
0022347547
-
Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells
-
White, M. F., R. Maron, and C. R. Kahn. 1985. Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells. Nature (London) 318:183-186.
-
(1985)
Nature (London)
, vol.318
, pp. 183-186
-
-
White, M.F.1
Maron, R.2
Kahn, C.R.3
-
56
-
-
0030002820
-
The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis
-
Yenush, L., R. Fernandez, M. G. Myers, Jr., T. C. Grammer, X. J. Sun, J. Blenis, J. H. Pierce, J. Schlessinger, and M. F. White. 1996. The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis. Mol. Cell. Biol. 16:2509-2517.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2509-2517
-
-
Yenush, L.1
Fernandez, R.2
Myers Jr., M.G.3
Grammer, T.C.4
Sun, X.J.5
Blenis, J.6
Pierce, J.H.7
Schlessinger, J.8
White, M.F.9
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