Comparison of subgroups assigned to medical regimens used to suppress cardiac ischemia (the Asymptomatic Cardiac Ischemia Pilot [ACIP] study)

American Journal of Cardiology

Volumn 77, Issue 15, 1996, Pages 1302-1309

  Pratt, Craig M ^{a,b,c,d,e,f,g,h,i}   McMahon, Robert P ^{a,b,c,d,e,f,g,h,i}   Goldstein, Sidney ^{a,b,c,d,e,f,g,h,i}   Pepine, Carl J ^{a,b,c,d,e,f,g,h,i}   Andrews, Thomas C ^{a,b,c,d,e,f,g,h,i}   Dyrda, Ihor ^{a,b,c,d,e,f,g,h,i}   Frishman, William H ^{a,b,c,d,e,f,g,h,i}   Geller, Nancy L ^{a,b,c,d,e,f,g,h,i}   Hill, James A ^{a,b,c,d,e,f,g,h,i}   Morgan, Nancy A ^{a,b,c,d,e,f,g,h,i}   Stone, Peter H ^{a,b,c,d,e,f,g,h,i}   Knatterud, Genell L ^{a,b,c,d,e,f,g,h,i,j}   Sopko, George ^{a,b,c,d,e,f,g,h,i}   Conti, C Richard ^{a,b,c,d,e,f,g,h,i}  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c ASTRAZENECA   (United Kingdom)

^d Marion Merrell Dow Inc   (United States)

^e PFIZER INC   (United States)

^f Applied Cardiac Systems   (United States)

^g Marquette Electronics Inc   (United States)

^h Mortara Instrument   (United States)

ⁱ Quinton Instrument Company   (United States)

^j MARYLAND MEDICAL RESEARCH INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DILTIAZEM; ISOSORBIDE DINITRATE; NIFEDIPINE; NITRATE;

ADULT; AGED; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; HEART MUSCLE ISCHEMIA; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ST SEGMENT DEPRESSION;

EID: 8944230649     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(96)00196-8     Document Type: Article

References (29)

1. 1. Pepine CJ. Ambulant myocardial ischemia and its prognostic implications. Circulation 1990;81:1136-1138.
2. 2. Rocco MB, Nabel EG, Campbell S, Goldman L. Prognostic importance of myocardial ischemia detected by ambulatory monitoring in patients with coronary disease. Circulation 1988;78:877-884.
3. 3. Aronow WS, Epstein S. Usefulness of silent myocardial ischemia detected by ambulatory electrocardiographic monitoring in predicting new coronary events in elderly patients. Am J Cardiol 1988;62:1295-1296.
4. 4. Deedwania PC, Carbojal EV. Silent ischemia during daily life is an independent predictor of mortality in stable angina. Circulation 1990;81;748-756.
5. 5. Johnson SM, Mauritson DR, Winniford MD, Willerson JT. Continuous electrocardiographic monitoring in patients with unstable angina pectoris: identification of high-risk subgroup with severe coronary disease, variant angina, and/ or impaired early prognosis. Am Heart J 1982;103:4-12.
6. 6. Gottlieb SO, Weisfeldt ML, Ouyang P, Mellits ED, Gerstenblith G. Silent ischemia predicts infarction and death during 2 year follow-up of unstable an-gina. J Am Coll Cardiol 1987;10:756-760.
7. 7. Rogers WJ, Bourassa MG, Andrews TL, Bertolet BD, Blumenthal RS, Chaitman B, Forman S, Geller NL, Goldberg AD, Habib GB, Masters RG, Moisa RB, Mueller H, Pearce DJ, Pepine C, Sopko G, Steingart RM, Stone PH, Knatterud GL, Conti CR, for the ACIP Investigators. The asymptomatic cardiac ischemia pilot (ACIP) study: outcome at one year for patients with asymptomatic cardiac ischemia randomized to medical therapy or revascularization. J Am Coll Cardiol 1995;26:594-605.
8. 8. Pepine CJ, Geller NL, Knatterud GL, Bourassa MG, Chaitman BR, Davies RF, Day P, Deanfield JE, Goldberg AD, McMahon RP, Mueller H, Ouyang P, Pratt C, Proschan M, Rogers WJ, Selwyn AP, Sharaf B, Sopko G, Stone PH, Conti CR, for the ACIP Investigators. The asymptomatic cardiac ischemia pilot (ACIP) study: design of a randomized clinical trial, baseline data and implications for a long-term outcome trial. J Am Coll Cardiol 1994;24:1-10.
9. 9. Conti CR, Knatterud GL, Sopko G. Erratum. J Am Coll Cardiol 1995;26:842.
10. 10. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research: Principles and Quantitative Methods. New York; Van Nostrand Reinhold; 1992:331-338.
11. 11. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research: Principles and Quantitative Methods. New York: Van Nostrand Reinhold; 1992:421-433.
12. 12. Kleinbaum DG, Kupper LL, Muller KE. Applied Regression Analysis and Other Multivariable Methods. 2nd ed. Boston: PWS-Kent Publishing; 1988:497-512.
13. 13. Breslow NE. Tests of hypotheses in overdispersed Poisson regression models. J Am Stat Assoc 1990;85:565-571.
14. 14. Hartigan PM, Parisi AF, Folland ED. Angina-free time on the treadmill as an alternate method for evaluating antianginal therapy. Am J Cardiol 1994;73:516-518.
15. 15. Prentice RL. Linear rank tests and right censored data. Biometrika 1978;65:167-179.
16. 16. SAS/STAT User's Guide. Ver. 6. Cary, NC: SAS Institute, Inc.; 1989:851-887.
17. 17. SAS/STAT User's Guide. Ver. 6. Cary, NC: SAS Institute, Inc.; 1989:1351-1454.
18. 18. Von Arnim T, Erath A. Nitrates and calcium antagonists for silent myocardial ischemia. Am J Cardiol 1988;61:15E-18E.
19. 19. Feng J, Feng X, Schneeweiss A. Efficacy of isosorbide-5-mononitrate on painful and silent myocardial ischemia after myocardial infarction. Am J Cardiol 1990;65:32J-35J.
20. 20. Deedwania PC, Carbajal EV, Nelson JR, Hait H. Anti-ischemic effects of atenolol vs. nifedipine in patients with coronary artery disease and ambulatory silent ischemia. J Am Coll Cardiol 1991;17:963-969.
21. 21. Hill JA, Gonzalez JI, Kolb R, Pepine CJ. Effects of atenolol alone, nifedipine alone and their combination on ambulant myocardial ischemia. Am J Cardiol 1991;67:671-675.
22. 22. Stone PH, Gibson RS, Glasser SP, DeWood MA, Parker JD, Kawanishi DT, Crawford MH, Messineo FC, Shook TL, Raby K, Curtis DG, Hoop RS, Young PM, Braunwald E, and the ASIS Study Center. Comparison of propranolol, diltiazem, and nifedipine in the treatment of ambulatory ischemia in patients with stable angina. Circulation 1990;82:1962-1972.
23. 23. Parodi O, Simonetti I, L'Abbate A, Maseri A. Verapamil vs. propranolol for angina at rest. Am J Cardiol 1982;50:923-928.
24. 24. Bertolet BD, Hill JA, Pepine CJ. Treatment strategies for daily life silent myocardial ischemia: a correlation with potential pathogenic mechanisms. Prog Cardiovasc Dis 1992;35:97-118.
25. 25. Gelman JS, Feldman RL, Scott E, Pepine CJ. Nicardipine for angina pectoris at rest and coronary arterial spasm. Am J Cardiol 1985;56:232-236.
26. 26. Juneau M, Theroux P, Waters D. Effect of diltiazem slow-release formulation on silent myocardial ischemia in stable coronary artery disease. The Canadian multicenter diltiazem study group. Am J Cardiol 1992;69:30B-35B.
27. 27. McMahon RP, Proschan M, Geller NL, Stone PH, Sopko G. Sample size calculation for clinical trials in which entry criteria and outcomes are counts of events. Stat Med 1994;13:859-870.
28. 28. Kjekshus J. Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials. Am J Cardiol 1986;57:43F-49F.
29. 29. Andrews TC, Fenton T, Toyosaki N, Glasser SP, Young PM, MacCallum G, Gibson RS, Shoor TL, Stone PH, for the ASIS Study Group. Subsets of ambulatory myocardial ischemia based on heart rate activity: circadian distribution and response to anti-ischemic medication. Circulation 1993;88:92-100.