Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs

Journal of Biological Chemistry

Volumn 271, Issue 28, 1996, Pages 16703-16711

  John Smith, K ^b   Scotland, Grant ^a   Beattie, James ^c   Trayer, Ian P ^b   Houslay, Miles D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c HANNAH RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; BACTERIAL PROTEIN; CHLORAMPHENICOL ACETYLTRANSFERASE; CYCLIC AMP; LEUCINE; PHOSPHODIESTERASE; PROLINE; TRYPTOPHAN; VALINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHIMERA; CONTROLLED STUDY; DELETION MUTANT; ENZYME STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTON NUCLEAR MAGNETIC RESONANCE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CELL MEMBRANE; DNA PRIMERS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PROTONS; RECOMBINANT FUSION PROTEINS; RNA SPLICING; SEQUENCE DELETION;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 8944228921     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.28.16703     Document Type: Article

References (40)

1. Krebs, E. G., and Beavo, J. A. (1979) Annu. Rev. Biochem. 43, 923-959
2. Beavo, J. A., Conti, M., and Heaslip, R. J. (1994) Mol. Pharmacol. 46, 399-405
3. Manganiello, V. C., Murata, T., Taira, M., Belfrage, P., and Degerman, E. (1995) Arch. Biochem. Biophys. 322, 1-13
4. Conti, M., Nemoz, G., Sette, C., and Vicini, E. (1995) Endocr. Rev. 16, 370-389
5. Rubin, C. S. (1994) Biochim. Biophys. Acta 1224, 467-479
6. Scott, J. D. (1991) Pharmacol. & Ther. 50, 123-145
7. Klauck, T. M., and Scott, J. D. (1995) Cell. Signalling 7, 747-757
8. Houslay, M. D., and Kilgour, E. (1990) (Beavo, J. A., and Houslay, M. D., eds) Molecular Pharmacology of Cell Regulation, Vol. 2, pp. 185-226, John Wiley & Sons Ltd., Chichester, UK
9. Shakur, Y., Pryde, J. G., and Houslay, M. D. (1993) Biochem. J. 292, 677-686
10. Houslay, M. D., and Marchmont, R. J. (1981) Biochem. J. 198, 703-706
11. Bolger, G., McPhee, I., and Houslay, M. D. (1996) J. Biol. Chem. 271, 1065-1071
12. McPhee, I., Pooley, L., Lobban, M., Bolger, G., and Houslay, M. D. (1995) Biochem. J. 310, 965-974
13. Horton, Y. M., Sullivan, M., and Houslay, M. D. (1995) Biochem. J. 308, 683-691
14. Milatovich, A., Bolger, G., Michaeli, T., and Francke, U. (1994) Somatic Cell Mol. Genet. 20, 75-86
15. Szpirer, C., Szpirer, J., Riviere, M., Swinnen, J., Vicini, E., and Conti, M. (1995) Cytogenet. Cell Genet. 69, 11-14
16. Swinnen, J. V., Joseph, D. R., and Conti, M. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5325-5329
17. Bolger, G. (1994) Cell. Signalling 6, 851-859
18. Davis, R. L., Takayasu, H., Eberwine, M., and Myres, J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 3604-3608
19. Shakur, Y., Wilson, M., Pooley, L., Lobban, M., Griffiths, S. L., Campbell, A. M., Beattie, J., Daly, C., and Houslay, M. D. (1995) Biochem. J. 306, 801-809
20. Scotland, G., and Houslay, M. D. (1995) Biochem. J. 308, 673-681
21. Sheffield, V. C., Cox, D. R., Lerman, L. S., and Myers, R. M. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 232-236
22. Brunger, A. T. (1992) X-PLOR, version 3.1, A System for X-ray Crystallography and NMR, President and Fellows of Harvard University, Yale University Press, Cambridge, MA
23. Lau, S. Y. M., Taneja, A. K., and Hodges, R. S. (1984) J. Biol. Chem. 259, 13253-13261
24. Dyson, H. J., Merutka, G., Waltho, J. P., Lerner, R. A., and Wright, P. E. (1992) J. Mol. Biol. 226, 795-817
25. Nelson, J. W., and Kallenbach, N. R. (1989) Biochemistry 28, 5256-5261
26. Ho, S. N., Hunt, H. D., Horten, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 44, 51-59
27. Dyson, H. J., Rance, M., Houghten, R. A., Lerner, R. A., and Wright, P. E. (1988) J. Mol. Biol. 201, 161-200
28. Hol, W. G. J., van Duijenen, P. T., and Berendsen, H. J. C. (1978) Nature 273, 443-446
29. Sali, D., Bycroft, M., and Fersht, A. R. (1988) Nature 335, 740-743
30. Richardson, J. S., and Richardson, D. C. (1988) Proteins Struct. Funct. Genet. 4, 229-239
31. Scholtz, J. M., Qian, H., Robbins, V. H., and Baldwin, R. L. (1993) Biochemistry 32, 9668-9676
32. Shoemaker, K. R., Kim, P. S., York, E. J., Stewart, J. M., and Baldwin, R. L. (1990) Nature 326, 563-567
33. Tirado-Rives, J., and Jorgensen, W. L. (1991) Biochemistry 30, 3864-3871
34. Fiori, W. R., Lundberg, K. M., and Millhauser, G. L. (1994) Nat. Struct. Biol. 1, 374-377
35. Fiori, W. R., and Millhauser, G. L. (1995) Biopolymers 37, 243-250
36. Kabsch, W., Mannherz, H. G., Suck, D., Pai, E. F., and Holmes, K. C. (1990) Nature 347, 37-44
37. MacArthur, M. W., and Thornton, J. M. (1991) J. Mol. Biol. 218, 397-412
38. Houslay, M. D., Scotland, G., Pooley, L., Spence, S., Wilkinson, I., McCallum, F., Julien, P., Rena, N. G., Michie, A. M., Erdogan, S., Zeng, L., Oconnell, J. C., Tobias, E. S., and MacPhee, I. (1995) Biochem. Soc. Trans. 23, 393-398
39. Kozak, M. (1986) Cell 44, 283-292
40. Conti, M., Swinnen, J. V., Tsikalas, K. E., and Jin, S. L. C. (1992) in Advances in Second Messenger & Phosphoprotein Research (Strade, S. J., and Hikaka, H., eds) Vol. 25, pp. 87-99, Raven Press, Ltd., New York