Characterization of a T cell line specific to an anti-Id antibody related to the carbohydrate antigen, sialyl SSEA-1, and the immunodominant T cell antigenic site of the antibody

Journal of Immunology

Volumn 157, Issue 2, 1996, Pages 661-669

  Tsuyuoka, Kiyotaka ^a   Yago, Kazuhiro ^a   Hirashima, Kunimi ^a   Ando, Shoji ^a   Hanai, Nobuo ^b   Saito, Hiromitsu ^b   Yamasaki, Motoo ^b   Takahashi, Katsutoshi ^c   Fukuda, Yoshihiro ^c   Nakao, Kazuwa ^c   Kannagi, Reiji ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE ANTIGEN; CD4 ANTIGEN; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; SIALOPROTEIN; STAGE SPECIFIC EMBRYO ANTIGEN 1; T LYMPHOCYTE ANTIGEN; TUMOR ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CANCER INHIBITION; CONTROLLED STUDY; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, CD15; CELL LINE; FIBROSARCOMA; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNIZATION, PASSIVE; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN VARIABLE REGION; LYMPH NODES; LYMPHOCYTE ACTIVATION; METHYLCHOLANTHRENE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; T-LYMPHOCYTES;

EID: 8944223514     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Hakomori, S., and R. Kannagi. 1983. Glycosphingolipids as tumor-associated and differentiation markers. J. Natl. Cancer Inst. 71:231.
2. Hakomori, S. 1985. Aberrant glycosylation in cancer cell membranes as focused on glycolipids: overview and perspectives. Cancer Res. 45:2405.
3. Solter, D., and B. B. Knowles. 1978. Monoclonal antibody defining a stage-specific embryonic antigen (SSEA-1). Proc. Natl. Acad. Sci. USA 75:5565.
4. Fox, N., I. Damjanov, A. Martinez-Hernandez, B. B. Knowles, and D. Solter. 1981. Immunohistochemical localization of the early embryonic antigen (SSEA-1) in postimplantation mouse embryos and fetal and adult tissues. Dev. Biol. 83:391.
5. Zenita, K., Y. Kitahara, A. Kitahara, K. Shigeta, K. Higuchi, K. Hirashima, T. Murachi, M. Miyake, T. Takeda, and R. Kannagi. 1988. Fucosylated type 2 chain polylactosamine antigens in human lung cancer. Int. J. Cancer 41:344.
6. Miyake, M., K. Zenita, O. Tanaka, Y. Okada, and R. Kannagi. 1988. Stage-specific expression of SSEA-1-related antigens in the developing lung of human embryos and its relation to the distribution of these antigens in lung cancers. Cancer Res. 48:7150.
7. Kannagi, R., Y. Fukushi, T. Tachikawa, A. Noda, S. Shin, K. Shigeta, N. Hiraiwa, Y. Fukuda, T. Inamoto, S. Hakomori, and H. Imura. 1986. Quantitative and qualitative characterization of cancer-associated serum glycoprotein antigens expressing fucosyl or sialosyl-fucosyl type 2 chain polylactosamine. Cancer Res. 46:2619.
8. Takada, A., K. Ohmori, T. Yoneda, K. Tsuyuoka, A. Hasegawa, M. Kiso, and R. Kannagi. 1993. Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res. 53:354.
9. Noguchi, M., N. Hiraiwa, K. Yoshimura, T. Nakatani, N. Chohnabayashi, Y. Nakamori, K. Nakata, H. Matushita, and H. Tanimoto. 1988. Clinical evaluation on the serum sialyl Lewis X-i (SLX) in primary lung cancer patients. J. Tumor Marker Oncol. 3:21.
10. Ono, K., K. Takahashi, Y. Hirabayashi, T. Itoh, Y. Hiraga, and M. Taniguchi. 1988. Mouse melanoma antigen recognized by Lyt-2- and L3T4- cytotoxic T-lymphocytes. Cancer Res. 48:2730.
11. Ishioka, G. Y., A. G. Lamont, D. Thomson, N. Bulbow, F. C. A. Gaeta, A. Sette, and H. M. Grey. 1992. MHC interaction and T cell recognition of carbohydrates and glycopeptides. J. Immunol. 148:2446.
12. Jerne, N. K. 1974. Towards a network theory of the immune system. Annu. Rev. Immunol. 125:373.
13. Nisonoff, A., and E. Lamoyi. 1981. Implication of the presence of an internal image of the antigen in anti-idiotypic antibodies: possible application to vaccine production. Clin. Immunol. Immunopathol. 21:397.
14. Jerne, N. K., J. Roland, and P. A. Cazenave. 1982. Recurrent idiotopes and internal images. EMBO J. 1:243.
15. Nisonoff, A. 1991. Idiotypes: concept and applications. J. Immunol. 147:2429.
16. Bona, C. A., E. Heber-Katz, and W. E. Paul. 1981. Idiotype-anti-idiotype regulation. I. Immunization with a Levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones. J. Exp. Med. 153:951.
17. Moser, M., O. Leo, J. Hiernaux, and J. Urbain. 1983. Idiotypic manipulation in mice: BALB/c mice can express the crossreactive idiotype of A/J mice. Proc. Natl. Acad. Sci. USA 80:4474.
18. Stein, K. E., and T. Soderstrom. 1984. Neonatal administration of idiotype or anti-idiotype primes for protection against Escherichia coli K13 infection in mice. J. Exp. Med. 160:1001.
19. Lee, V. K., K. E. Hellstrom, and G. T. Nepom. 1986. Idiotypic interactions in immune responses to tumor-associated antigens. Biochim. Biophys. Acta 865: 127.
20. Schick, M. R., G. R. Dreesman, and R. C. Kennedy. 1987. Induction of an anti-hepatitis B surface antigen response in mice by noninternal image (Ab2a) anti-idiotypic antibodies. J. Immunol. 138:3419.
21. Raychaudhuri, S., Y. Saeki, H. Fuji, and H. Köhler. 1986. Tumor-specific idiotype vaccines. I. Generation and characterization of internal image tumor antigen. J. Immunol. 137:1743.
22. Chen, J-J., Y. Saeki, L. Shi, and H. Köhler. 1989. Tumor idiotype vaccines. VI. Synergistic anti-tumor effects with combined internal image anti-idiotypes and chemotherapy. J. Immunol. 143:1053.
23. Mittelman, A., Z. J. Chen, T. Kageshita, H. Yang, M. Yamada, P. Baskind, N. Goldberg, C. Puccio, T. Ahmed, Z. Arlin, and S. Ferrone. 1990. Active specific immunotherapy in patients with melanoma: a clinical trial with mouse anti-idiotypic monoclonal antibodies elicited with syngenic anti-high-molecular weight melanoma-associated antigen monoclonal antibodies. J. Clin. Invest. 86: 2136.
24. Robins, R. A., G. W. L. Denton, J. D. Hardcastle, E. B. Austin, R. W. Baldwin, and L. G. Durrant. 1991. Antitumor immune response and interleukin 2 production induced in colorectal cancer patients by immunization with human monoclonal anti-idiotypic antibody. Cancer Res. 51:5425.
25. Ishihara, G., K. Hirashima, A. Takada, K. Ohmori, T. Mori, and R. Kannagi. 1992. Induction of tumor-specific immunity against syngeneic tumor by anti-idiotypic antibodies directed to anti-carbohydrate antibodies. Jpn. Arch. Int. Med. 39:51.
26. H7183-encoded antibodies directed to a murine embryonic carbohydrate antigen, Lewis Y, as ascertained by syngenic anti-idiotype monoclonal antibodies. J. Immunol. 145:224.
27. Sacks, D. L., L. V. Kirchhoff, S. Hieny, and A. Sher. 1985. Molecular mimicry of a carbohydrate epitope on a major surface glycoprotein of Trypanosoma cruzi by using anti-idiotypic antibodies. J. Immunol. 135:4155.
28. Hastings, A., S. L. Morrison, S. Kanda, R. E. Saxton, and R. F. Irie. 1992. Production and characterization of a murine/human chimeric anti-idiotype antibody that mimics ganglioside. Cancer Res. 42:1681.
29. Delisi, C., and J. A. Berzofsky. 1985. T-cell antigenic sites tend to be amphipathic structures. Proc. Natl. Acad. Sci. USA 82:7048.
30. Margalit, H., J. L. Spouge, J. L. Cornette, K. B. Cease, C Delisi, and J. A. Berzofsky. 1987. Prediction of immunodominant helper T cell antigenic sites from the primary sequence. J. Immunol. 138:2213.
31. Rothbard, J. B., and W. R. Taylor. 1988. A sequence pattern common to T cell epitopes. EMBO J. 7:93.
32. Sette, A., S. Buus, E. Appella, J. A. Smith, R. Chesnut, C. Miles, S. M. Colon, and H. M. Grey. 1989. Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis. Proc. Natl. Acad Sci. USA 86:3296.
33. 6) in normal and tumor tissues defined by its monoclonal antibody FH-6. Cancer Res. 45:3711.
34. Kappler, J. W., B. Skidmore, J. White, and P. Marrack. 1981. Antigen-inducible, H-2-restricted, interleukin-2-producimg T cell hybridomas: lack of independent antigen and H-2 recognition. J. Exp. Med. 153:1198.
35. Dialynas, D., Z. Quan, K. Wall, A. Pierres, J. Quintans, M. Loken, M. Pierres, and F. Fitch. 1983. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK-1.5: similarity of L3T4 to the human Leu 3/T4 molecule and the possible involvement of L3T4 in class II MHC antigen reactivity. J. Immunol. 131:2445.
36. Sarminento, M., A. L. Glasebrook, and F. W. Fitch. 1980. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125:2665.
37. Staerz, U., H. Rammansee, J. Benedetto, and M. Bevan. 1985. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen recepter. J. Immunol. 134:3994.
38. Köhler, G., and C. Milstein. 1975. Continuous culture of fused cells secreting antibody of predefined specificity. Nature 256:495.
39. Kimoto, M. and C. G. Fathman. 1980. Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A region gene products function effectively in antigen presentation. J. Exp. Med. 152:759.
40. Ohmori, K., T. Yoneda, K. Shigeta, K. Hirashima, M. Kanai, S. Itai, T. Sasaoki, S. Arii, H. Arita, and R. Kannagi. 1989. Sialyl SSEA-1 antigen as a carbohydrate marker of human natural killer cells and immature lymphoid cells. Blood 74:255.
41. Kehry, M. R., and S. A. Hudak. 1989. Characterization of B-cell populations bearing Fcε recepter II. Cell. Immunol. 118:504.
42. Bottomly, K., and D. E. Mosier. 1981. Antigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted. J. Exp. Med. 154:411.
43. Cerny, J., J. S. Smith, C. Webb, and P. W. Tucker. 1988. Properties of anti-idiotypic T cell lines propagated with syngeneic B lymphocytes I. T cells bind intact idiotypes and discriminate between the somatic idiotypic variants in a manner similar to the anti-idiotypic antibodies. J. Immunol. 141:3718.
44. Janeway, C. A., Jr., J. Rojo, P. Portoles, E. Dunn, and K. Bottomly. 1990. Idiotypic interaction between B- and T-lymphocyte recepters. In Idiotype Networks in Biology and Medicine. A. D. M. E. Osterhaus and F. G. C. M. UytdeHaag, eds. Excerpta Medica, Amsterdam, p. 125.
45. Kabat, E. A. 1982. Antibody diversity versus antibody complementarity. Pharmacol. Rev. 34:23.
46. Bogen, B., B. Malissen, and W. Haas. 1986. Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules. Eur. J. Immunol. 16:1373.
47. + idiotype-specific T cell. J. Immunol. 142:409.
48. Mazel, S. M., A. Y. Rudensky, and V. L. Yurin. 1990. Immunogloblin-specific T-B cell interaction. III. B cell activation by immunogloblin-recognizing T cell clones. Eur. J. Immunol. 20:833.
49. Saeki, Y., J-J. Chen, L. Ski, Y. Okuda, and H. Kohler. 1990. Idiotype-specific T helper clones recognize a variable H chain determinant. J. Immunol. 144:1625.
50. Wilson, A., A. J. T. George, C. A. King, and F. K. Stevenson. 1990. Recognition of a B cell lymphoma by anti-idiotypic T cells. J. Immunol. 145:3937.
51. b-specific T cells recognize a signal-minus form of the V-CH3b antigen. Eur. J. Immunol. 21:1411.
52. Velge-Roussel, F., C. Auriault, C. Mazingue, and A. Capron. 1991. Functional analysis of a T cell line specific for anti-idiotypic antibodies to a Schistosoma mansoni protective epitope. I. Role in the anti-S. mansoni antibody response. J. Immunol. 147:3960.
53. Weiss, S., and B. Bogen. 1991. MHC class II-restricted presentation of intracellular antigen. Cell 64:767.
54. Brett, S. J., K. B. Cease, and J. A. Berzofsky. 1988. Influences of antigen processing on the expression of the T cell repertoire: evidence for MHC-specific hindering structures on the products of processing. J. Exp. Med. 168:357.
55. Vacchio, M. S., J. A. Berzofsky, U. Kryzch, J. A. Smith, R. J. Hodes, and A. Finnegan. 1989. Sequences outside a minimal immunodominant site exert negative effects on regulation by staphylococcal nuclease-specific T cell clones. J. Immunol. 143:2814.
56. Eisenlohr, L. C., J. W. Yewdell, and J. R. Bennink. 1992. Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes. J. Exp. Med. 175:481.
57. Del Val, M., H.-J. Schlicht, T. Ruppert, M. J. Reddenhase, and U. H. Kozinowski. 1991. Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein. Cell 66: 1145.
58. Pride, M. W., H. Shi, J. M. Anchin, D. S. Linthicum, P. T. LoVerde, A. Thakur, and Y. Thanavala. 1992. Molecular mimicry of hepatitis B surface antigen by an anti-idiotype-derived synthetic peptide. Proc. Natl. Acad. Sci. USA 89:11900.
59. Hebert, J., D. Bernier, Y. Boutin, M. Jobin, and W. Mourad. 1990. Generation of anti-idiotypic and anti-anti-idiotypic monoclonal antibodies in the same fusion: support of Jerne's network theory. J. Immunol. 144:4256.