메뉴 건너뛰기




Volumn 14, Issue 6, 1996, Pages 1798-1809

Phase I trial of iodine 131-labeled COL-1 in patients with gastrointestinal malignancies: Influence of serum carcinoembryonic antigen and tumor bulk on pharmacokinetics

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; IODINE 131; MITOMYCIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY COL 1; NITROSOUREA DERIVATIVE; UNCLASSIFIED DRUG;

EID: 8944222567     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1996.14.6.1798     Document Type: Article
Times cited : (40)

References (56)
  • 1
    • 0021902411 scopus 로고
    • CEA-related antigens: Molecular biology and clinical significance
    • Shively JE, Beatty JD: CEA-related antigens: Molecular biology and clinical significance. Crit Rev Oncol Hematol 2:355-399, 1985
    • (1985) Crit Rev Oncol Hematol , vol.2 , pp. 355-399
    • Shively, J.E.1    Beatty, J.D.2
  • 2
    • 0023810403 scopus 로고
    • Clinical applications of carcinoembryonic antigen
    • Sikorska H, Shuster J, Gold P: Clinical applications of carcinoembryonic antigen. Cancer Detect Prev 12:321-355, 1988
    • (1988) Cancer Detect Prev , vol.12 , pp. 321-355
    • Sikorska, H.1    Shuster, J.2    Gold, P.3
  • 3
    • 0025320277 scopus 로고
    • Tumor specificity of monoclonal antibodies to carcinoembryonic antigen
    • Zoubir F, Zeromski J, Sikora J, et al: Tumor specificity of monoclonal antibodies to carcinoembryonic antigen. Tumor Biol 11:5-19, 1990
    • (1990) Tumor Biol , vol.11 , pp. 5-19
    • Zoubir, F.1    Zeromski, J.2    Sikora, J.3
  • 4
    • 0024407253 scopus 로고
    • Antigenic sites in carcinoembryonic antigen
    • Hammarstrom S, Shively JE, Paxton RJ, et al.: Antigenic sites in carcinoembryonic antigen. Cancer Res 49:4852-4858, 1989
    • (1989) Cancer Res , vol.49 , pp. 4852-4858
    • Hammarstrom, S.1    Shively, J.E.2    Paxton, R.J.3
  • 5
    • 0021265319 scopus 로고
    • Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli
    • Cabilly S, Riggs AD, Pande H, et al.: Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli. Proc Natl Acad Sci USA 81:3273-3277, 1984
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3273-3277
    • Cabilly, S.1    Riggs, A.D.2    Pande, H.3
  • 6
    • 0026616750 scopus 로고
    • Cancer imaging with CEA antibodies: Historical and current perspectives
    • Goldenberg DM: Cancer imaging with CEA antibodies: Historical and current perspectives. Int J Biol Markers 7:183-188, 1992
    • (1992) Int J Biol Markers , vol.7 , pp. 183-188
    • Goldenberg, D.M.1
  • 7
    • 0025970162 scopus 로고
    • Current treatment approaches in colorectal cancer
    • Grem JL: Current treatment approaches in colorectal cancer. Semin Oncol 18:17-26, 1991
    • (1991) Semin Oncol , vol.18 , pp. 17-26
    • Grem, J.L.1
  • 9
    • 0025731301 scopus 로고
    • A phase-I study of repeated therapy with radiolabelled antibody
    • Ledermann JA, Begent RH, Massof C, et al: A phase-I study of repeated therapy with radiolabelled antibody. Int J Cancer 47:659-664, 1991
    • (1991) Int J Cancer , vol.47 , pp. 659-664
    • Ledermann, J.A.1    Begent, R.H.2    Massof, C.3
  • 10
    • 84871468702 scopus 로고
    • RE-186 radiolabeled anti-CEA monoclonal antibody (mAb) therapy: Phase 1 dose escalation study
    • abstr 716
    • Weiden P, Fer M, Schroff R, et al.: RE-186 radiolabeled anti-CEA monoclonal antibody (mAb) therapy: Phase 1 dose escalation study. Proc Am Soc Clin Oncol 9:185, 1990 (abstr 716)
    • (1990) Proc Am Soc Clin Oncol , vol.9 , pp. 185
    • Weiden, P.1    Fer, M.2    Schroff, R.3
  • 11
    • 0023035090 scopus 로고
    • Monoclonal antibody immunoradiometric assay for an antigenic determinant (CA 72) on a novel pancarcinoma antigen (TAG-72)
    • Klug TL, Sattler MA, Colcher D, et al: Monoclonal antibody immunoradiometric assay for an antigenic determinant (CA 72) on a novel pancarcinoma antigen (TAG-72). Int J Cancer 38:661-669, 1986
    • (1986) Int J Cancer , vol.38 , pp. 661-669
    • Klug, T.L.1    Sattler, M.A.2    Colcher, D.3
  • 12
    • 0025115337 scopus 로고
    • 131I-labeled anti-carcinoembryonic antigen monoclonal antibody
    • 131I-labeled anti-carcinoembryonic antigen monoclonal antibody. Cancer Res 50:1039s-1042s, 1990
    • (1990) Cancer Res , vol.50
    • Siegel, J.A.1    Pawlyk, D.A.2    Lee, R.E.3
  • 13
    • 0027406142 scopus 로고
    • Clinical evaluation of tumor targeting with a high-affinity, anticarcinoembryonic-antigen-specific, murine monoclonal antibody, MN-14
    • Sharkey RM, Goldenberg DM, Murthy S, et al: Clinical evaluation of tumor targeting with a high-affinity, anticarcinoembryonic-antigen-specific, murine monoclonal antibody, MN-14. Cancer 71:2082-2096, 1993
    • (1993) Cancer , vol.71 , pp. 2082-2096
    • Sharkey, R.M.1    Goldenberg, D.M.2    Murthy, S.3
  • 14
    • 0022373482 scopus 로고
    • Definition by monoclonal antibodies of a repertoire of epitopes on carcinoembryonic antigen differentially expressed in human colon carcinomas versus normal adult tissues
    • Muraro R, Wunderlich D, Thor A, et al: Definition by monoclonal antibodies of a repertoire of epitopes on carcinoembryonic antigen differentially expressed in human colon carcinomas versus normal adult tissues. Cancer Res 45:5769-5780, 1985
    • (1985) Cancer Res , vol.45 , pp. 5769-5780
    • Muraro, R.1    Wunderlich, D.2    Thor, A.3
  • 15
    • 0024446545 scopus 로고
    • Serologic mapping and biochemical characterization of the carcinoembryonic antigen epitopes using fourteen distinct monoclonal antibodies
    • Kuroki M, Greiner JW, Simpson JF, et al: Serologic mapping and biochemical characterization of the carcinoembryonic antigen epitopes using fourteen distinct monoclonal antibodies. Int J Cancer 44:208-218, 1989
    • (1989) Int J Cancer , vol.44 , pp. 208-218
    • Kuroki, M.1    Greiner, J.W.2    Simpson, J.F.3
  • 16
    • 0021328611 scopus 로고
    • Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells
    • Dillman RO, Beauregard JC, Sobol RE, et al: Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells. Cancer Res 44:2213-2218, 1984
    • (1984) Cancer Res , vol.44 , pp. 2213-2218
    • Dillman, R.O.1    Beauregard, J.C.2    Sobol, R.E.3
  • 17
    • 0025373376 scopus 로고
    • Murine monoclonal antibodies against carcinoembryonic antigen
    • Sharkey RM, Goldenberg DM, Goldenberg H, et al: Murine monoclonal antibodies against carcinoembryonic antigen. Cancer Res 50:2823-2831, 1990
    • (1990) Cancer Res , vol.50 , pp. 2823-2831
    • Sharkey, R.M.1    Goldenberg, D.M.2    Goldenberg, H.3
  • 18
    • 0023240385 scopus 로고
    • Differential expression of carcinoembryonic antigen in early gastric adenocarcinomas versus benign gastric lesions defined by monoclonal antibodies reactive with restricted antigen epitopes
    • Ohuchi N, Wunderlich D, Fujita J, et al: Differential expression of carcinoembryonic antigen in early gastric adenocarcinomas versus benign gastric lesions defined by monoclonal antibodies reactive with restricted antigen epitopes. Cancer Res 47:3565-3571, 1987
    • (1987) Cancer Res , vol.47 , pp. 3565-3571
    • Ohuchi, N.1    Wunderlich, D.2    Fujita, J.3
  • 19
    • 0027380864 scopus 로고
    • Therapeutic efficacy of a high-affinity anticarcinoembryonic antigen monoclonal antibody (COL-1)
    • Siler K, Eggensperger D, Hand PH, et al: Therapeutic efficacy of a high-affinity anticarcinoembryonic antigen monoclonal antibody (COL-1). Biotechnol Ther 4:163-181, 1993
    • (1993) Biotechnol Ther , vol.4 , pp. 163-181
    • Siler, K.1    Eggensperger, D.2    Hand, P.H.3
  • 20
    • 0017874586 scopus 로고
    • Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril
    • Fraker PJ, Depasquale-Jardieu P, Zwickl CM, et al: Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem Biophys Res Commun 80:849-857, 1978
    • (1978) Biochem Biophys Res Commun , vol.80 , pp. 849-857
    • Fraker, P.J.1    Depasquale-Jardieu, P.2    Zwickl, C.M.3
  • 23
    • 0027537029 scopus 로고
    • Bone marrow dosimetry for radioimmunotherapy: Theorectical considerations
    • Sgouros G: Bone marrow dosimetry for radioimmunotherapy: Theorectical considerations. J Nucl Med 34:689-694, 1993
    • (1993) J Nucl Med , vol.34 , pp. 689-694
    • Sgouros, G.1
  • 24
    • 0023846125 scopus 로고
    • "Sandwich"-type immunoassay of carcinoembryonic antigen in patients receiving murine monoclonal antibodies for diagnosis and therapy
    • Primus FJ, Kelley EA, Hansen HJ, et al: "Sandwich"-type immunoassay of carcinoembryonic antigen in patients receiving murine monoclonal antibodies for diagnosis and therapy. Clin Chem 34:261-264, 1988
    • (1988) Clin Chem , vol.34 , pp. 261-264
    • Primus, F.J.1    Kelley, E.A.2    Hansen, H.J.3
  • 25
    • 0025960381 scopus 로고
    • Assay for the detection of anti-idiotypic antibodies to monoclonal antibody B72.3
    • Ferroni P, Milenic DE, Schlom J, et al: Assay for the detection of anti-idiotypic antibodies to monoclonal antibody B72.3. J Clin Lab Anal 4:465-473, 1990
    • (1990) J Clin Lab Anal , vol.4 , pp. 465-473
    • Ferroni, P.1    Milenic, D.E.2    Schlom, J.3
  • 26
    • 0025303384 scopus 로고
    • In vivo fate of monoclonal antibody B72.3 in patients with colorectal cancer
    • Colcher D, Milenic DE, Ferroni P, et al: In vivo fate of monoclonal antibody B72.3 in patients with colorectal cancer. J Nucl Med 31:1133-1142, 1990
    • (1990) J Nucl Med , vol.31 , pp. 1133-1142
    • Colcher, D.1    Milenic, D.E.2    Ferroni, P.3
  • 27
    • 0016662127 scopus 로고
    • Augmentation of thyrotropin responses to thyrotropin releasing hormone following small decreases in serum thyroid hormone concentrations
    • Saberi M, Utiger RD: Augmentation of thyrotropin responses to thyrotropin releasing hormone following small decreases in serum thyroid hormone concentrations. J Clin Endocrinol Metab 40:435-441, 1975
    • (1975) J Clin Endocrinol Metab , vol.40 , pp. 435-441
    • Saberi, M.1    Utiger, R.D.2
  • 28
    • 0023095473 scopus 로고
    • Therapeutic application of radiolabeled monoclonal antibody UJ13A in children with disseminated neuroblastoma
    • Lashford L, Jones D, Pritchard J, et al: Therapeutic application of radiolabeled monoclonal antibody UJ13A in children with disseminated neuroblastoma. NCI Monographs 3:53-57, 1987
    • (1987) NCI Monographs , vol.3 , pp. 53-57
    • Lashford, L.1    Jones, D.2    Pritchard, J.3
  • 32
    • 0001037471 scopus 로고
    • Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinoma by external photoscanning and tomoscintigraphy
    • Mach JP, Buchegger F, Forni M, et al: Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinoma by external photoscanning and tomoscintigraphy. Immunol Today 2:239-249, 1981
    • (1981) Immunol Today , vol.2 , pp. 239-249
    • Mach, J.P.1    Buchegger, F.2    Forni, M.3
  • 33
    • 0020415569 scopus 로고
    • Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: First clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen
    • Berche C, Mach J-P, Lumbroso J, et al: Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: First clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen. Br Med J 285:1447-1451, 1982
    • (1982) Br Med J , vol.285 , pp. 1447-1451
    • Berche, C.1    Mach, J.-P.2    Lumbroso, J.3
  • 34
    • 0020685111 scopus 로고
    • Localisation of metastatic carcinoma by a radiolabelled monoclonal antibody
    • Smedley HM, Finan P, Lennox ES, et al: Localisation of metastatic carcinoma by a radiolabelled monoclonal antibody. Br J Cancer 47:253-259, 1983
    • (1983) Br J Cancer , vol.47 , pp. 253-259
    • Smedley, H.M.1    Finan, P.2    Lennox, E.S.3
  • 36
    • 0006005273 scopus 로고
    • Intraperitoneal versus intravenous injection of radiolabelled monoclonal antibodies in patients with colorectal carcinoma
    • abstr
    • Paganelli G, Riva P, Sarti G, et al: Intraperitoneal versus intravenous injection of radiolabelled monoclonal antibodies in patients with colorectal carcinoma. Br J Cancer 54:542-543, 1986 (abstr)
    • (1986) Br J Cancer , vol.54 , pp. 542-543
    • Paganelli, G.1    Riva, P.2    Sarti, G.3
  • 37
    • 0022883828 scopus 로고
    • Polyclonal and monoclonal anti-CEA antibodies in immunolocalization of colorectal cancer
    • Wahren B, Hammarstrom S, Harmenberg U, et al: Polyclonal and monoclonal anti-CEA antibodies in immunolocalization of colorectal cancer. Tumour Biol 7:361-369, 1986
    • (1986) Tumour Biol , vol.7 , pp. 361-369
    • Wahren, B.1    Hammarstrom, S.2    Harmenberg, U.3
  • 40
    • 0024474818 scopus 로고
    • 111In-labelled monoclonal antibody against carcinoembryonic antigen in colorectal cancer and of some biological factors affecting its uptake
    • 111In-labelled monoclonal antibody against carcinoembryonic antigen in colorectal cancer and of some biological factors affecting its uptake. Int J Colorectal Dis 4:97-108, 1989
    • (1989) Int J Colorectal Dis , vol.4 , pp. 97-108
    • Granowska, M.1    Jass, J.R.2    Britton, K.E.3
  • 41
    • 0025195293 scopus 로고
    • Pharmacokinetics in patients of an anti-carcinoembryonic antigen
    • Hnatowich DJ, Rusckowski M, Brill AB, et al: Pharmacokinetics in patients of an anti-carcinoembryonic antigen. Cancer Res 50:7272-7278, 1990
    • (1990) Cancer Res , vol.50 , pp. 7272-7278
    • Hnatowich, D.J.1    Rusckowski, M.2    Brill, A.B.3
  • 42
    • 0022220810 scopus 로고
    • In vivo kinetics of radiolabeled monoclonal anti-CEA antibodies in animal models
    • Hagan PL, Halpern SE, Chen A, et al: In vivo kinetics of radiolabeled monoclonal anti-CEA antibodies in animal models. J Nucl Med 26:1418-1423, 1985
    • (1985) J Nucl Med , vol.26 , pp. 1418-1423
    • Hagan, P.L.1    Halpern, S.E.2    Chen, A.3
  • 43
    • 0026032159 scopus 로고
    • Initial clinical study of indium-111 -labeled clone 110
    • Griffin TW, Brill AB, Stevens S, et al: Initial clinical study of indium-111 -labeled clone 110. J Clin Oncol 9:631-640, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 631-640
    • Griffin, T.W.1    Brill, A.B.2    Stevens, S.3
  • 44
    • 0026763061 scopus 로고
    • The presence of bulky tumor mass can decrease the uptake and therapeutic efficacy of radiolabeled antibodies in small tumors
    • Boerman OC, Sharkey RM, Blumenthal RD, et al: The presence of bulky tumor mass can decrease the uptake and therapeutic efficacy of radiolabeled antibodies in small tumors. Int J Cancer 51:470-475, 1992
    • (1992) Int J Cancer , vol.51 , pp. 470-475
    • Boerman, O.C.1    Sharkey, R.M.2    Blumenthal, R.D.3
  • 45
    • 0027443153 scopus 로고
    • Pharmacologic-based dosing of carboplatin: A better method
    • Hande KR: Pharmacologic-based dosing of carboplatin: A better method. J Clin Oncol 11:2295-2296, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 2295-2296
    • Hande, K.R.1
  • 46
    • 0022446735 scopus 로고
    • Limitations of radiolableled monoclonal antibodies for localization of human neoplasms
    • Epenetos AA, Snook D, Durbin H, et al: Limitations of radiolableled monoclonal antibodies for localization of human neoplasms. Cancer Res 46:3183-3191, 1986
    • (1986) Cancer Res , vol.46 , pp. 3183-3191
    • Epenetos, A.A.1    Snook, D.2    Durbin, H.3
  • 47
    • 0022654718 scopus 로고
    • Illusions of tumour killing using radiolabeled antibodies
    • Vaughan ATM, Bradwell AR, Dykes PW, et al: Illusions of tumour killing using radiolabeled antibodies. Lancet 1:1492-1493, 1986
    • (1986) Lancet , vol.1 , pp. 1492-1493
    • Vaughan, A.T.M.1    Bradwell, A.R.2    Dykes, P.W.3
  • 48
    • 0027484445 scopus 로고
    • Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support
    • Press OW, Eary JF, Appelbaum FR, et al: Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support. N Engl J Med 329:1219-1224, 1993
    • (1993) N Engl J Med , vol.329 , pp. 1219-1224
    • Press, O.W.1    Eary, J.F.2    Appelbaum, F.R.3
  • 49
    • 0027208577 scopus 로고
    • Radioimmunotherapy of B-cell lymphoma with [131]anti-B1 (anti-CD20) antibody
    • Kaminski MS, Zasadny KR, Francis IR, et al: Radioimmunotherapy of B-cell lymphoma with [131]anti-B1 (anti-CD20) antibody. N Engl J Med 329:459-465, 1993
    • (1993) N Engl J Med , vol.329 , pp. 459-465
    • Kaminski, M.S.1    Zasadny, K.R.2    Francis, I.R.3
  • 50
    • 0025014611 scopus 로고
    • Use of hematopoietic growth factors to control myelosuppression caused by radioimmunotherapy
    • Blumenthal RD, Sharkey RM, Quinn LM, et al: Use of hematopoietic growth factors to control myelosuppression caused by radioimmunotherapy. Cancer Res 50:1003s-1007s, 1990 (suppl)
    • (1990) Cancer Res , vol.50 , Issue.SUPPL.
    • Blumenthal, R.D.1    Sharkey, R.M.2    Quinn, L.M.3
  • 51
    • 0027339201 scopus 로고
    • Biologic properties of a CH2 domain-deleted recombinant immunoglobulin
    • Slavin-Chiorini DC, Horan Hand PH, Kashmiri SV, et al: Biologic properties of a CH2 domain-deleted recombinant immunoglobulin. Int J Cancer 53:97-103, 1993
    • (1993) Int J Cancer , vol.53 , pp. 97-103
    • Slavin-Chiorini, D.C.1    Horan Hand, P.H.2    Kashmiri, S.V.3
  • 52
    • 0025823009 scopus 로고
    • Monoclonal antibody-based therapy of a human tumor xenograft with a 177-lutetium (177Lu) labeled immunoconjugate
    • Schlom J, Siler K, Milenic DE, et al: Monoclonal antibody-based therapy of a human tumor xenograft with a 177-lutetium (177Lu) labeled immunoconjugate. Cancer Res 51:2889-2896, 1991
    • (1991) Cancer Res , vol.51 , pp. 2889-2896
    • Schlom, J.1    Siler, K.2    Milenic, D.E.3
  • 53
    • 84871466895 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann L, Clark M, Waldmann H, et al: Reshaping human antibodies for therapy. Nature 349:293-299, 1988
    • (1988) Nature , vol.349 , pp. 293-299
    • Riechmann, L.1    Clark, M.2    Waldmann, H.3
  • 55
    • 0025924795 scopus 로고
    • 90Y-labeled C110 anti-carcinoembryonic antigen immunotoxin: A therapeutic immunoconjugate for human colon cancer
    • 90Y-labeled C110 anti-carcinoembryonic antigen immunotoxin: A therapeutic immunoconjugate for human colon cancer. Ca Res 51:255-260, 1991
    • (1991) Ca Res , vol.51 , pp. 255-260
    • Ito, T.1    Qui, H.2    Collins, J.A.3
  • 56
    • 0025987026 scopus 로고
    • Anthracycline immunoconjugates prepared by a site-specific linkage via an aminodextran intermediated carrier
    • Shih LS, Goldenberg DM, Xuan H, et al: Anthracycline immunoconjugates prepared by a site-specific linkage via an aminodextran intermediated carrier. Cancer Res 51:4192-4198, 1991
    • (1991) Cancer Res , vol.51 , pp. 4192-4198
    • Shih, L.S.1    Goldenberg, D.M.2    Xuan, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.