-
1
-
-
0030005001
-
After initial setback, IL-12 regaining popularity
-
S. Jenks After initial setback, IL-12 regaining popularity J. Natl. Cancer Inst. 88 1996 576
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 576
-
-
Jenks, S.1
-
2
-
-
0000824394
-
Cancer trial of interleukin-12 halted
-
E. Marshall Cancer trial of interleukin-12 halted Science 268 1995 1555
-
(1995)
Science
, vol.268
, pp. 1555
-
-
Marshall, E.1
-
3
-
-
0030887047
-
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
-
M.B. Atkins, M.J. Robertson, M. Gordon, M.T. Lotze, M. DeCoste, J.S. DuBois, J. Ritz, A.B. Sandler, H.D. Edington, P.D. Garzone, J.W. Mier, C.M. Canning, L. Battiato, H. Tahara, M.L. Sherman Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies Clin. Cancer Res. 3 1997 409
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 409
-
-
Atkins, M.B.1
Robertson, M.J.2
Gordon, M.3
Lotze, M.T.4
Decoste, M.5
Dubois, J.S.6
Ritz, J.7
Sandler, A.B.8
Edington, H.D.9
Garzone, P.D.10
Mier, J.W.11
Canning, C.M.12
Battiato, L.13
Tahara, H.14
Sherman, M.L.15
-
4
-
-
0033017095
-
Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: A direct comparison with systemic IL-12 protein therapy
-
A.L. Rakhmilevich, J.G. Timmins, K. Janssen, E.L. Pohlmann, M.J. Sheehy, N.S. Yang Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity A direct comparison with systemic IL-12 protein therapy J. Immunother. 22 1999 135
-
(1999)
J. Immunother.
, vol.22
, pp. 135
-
-
Rakhmilevich, A.L.1
Timmins, J.G.2
Janssen, K.3
Pohlmann, E.L.4
Sheehy, M.J.5
Yang, N.S.6
-
5
-
-
0033933974
-
Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanism
-
A.L. Rakhmilevich, K. Janssen, Z. Hao, P.M. Sondel, N.S. Yang Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanism Cancer Gene Ther. 7 2000 826
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 826
-
-
Rakhmilevich, A.L.1
Janssen, K.2
Hao, Z.3
Sondel, P.M.4
Yang, N.S.5
-
6
-
-
0036726133
-
Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model
-
F. Shi, A.L. Rakhmilevich, C.P. Heise, K. Oshikawa, P.M. Sondel, N.S. Yang, D.M. Mahvi Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model Mol. Cancer Ther. 1 2002 949
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 949
-
-
Shi, F.1
Rakhmilevich, A.L.2
Heise, C.P.3
Oshikawa, K.4
Sondel, P.M.5
Yang, N.S.6
Mahvi, D.M.7
-
7
-
-
0032943223
-
Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors
-
S.M. Weber, F. Shi, C. Heise, T. Warner, D.M. Mahvi Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors Ann. Surg. Oncol. 6 1999 186
-
(1999)
Ann. Surg. Oncol.
, vol.6
, pp. 186
-
-
Weber, S.M.1
Shi, F.2
Heise, C.3
Warner, T.4
Mahvi, D.M.5
-
8
-
-
0031895957
-
Vaccination with IL-12 gene-modified autologous melanoma cells: Preclinical results and a first clinical phase I study
-
Y. Sun, K. Jurgovsky, P. Moller, S. Alijagic, T. Dorbic, J. Georgieva, B. Wittig, D. Schadendorf Vaccination with IL-12 gene-modified autologous melanoma cells Preclinical results and a first clinical phase I study Gene Ther. 5 1998 481
-
(1998)
Gene Ther.
, vol.5
, pp. 481
-
-
Sun, Y.1
Jurgovsky, K.2
Moller, P.3
Alijagic, S.4
Dorbic, T.5
Georgieva, J.6
Wittig, B.7
Schadendorf, D.8
-
9
-
-
0032528446
-
The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor
-
C.S. Tannenbaum, R. Tubbs, D. Armstrong, J.H. Finke, R.M. Bukowski, T.A. Hamilton The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor J. Immunol. 161 1998 927
-
(1998)
J. Immunol.
, vol.161
, pp. 927
-
-
Tannenbaum, C.S.1
Tubbs, R.2
Armstrong, D.3
Finke, J.H.4
Bukowski, R.M.5
Hamilton, T.A.6
-
10
-
-
0033539579
-
Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNA
-
K. Oshikawa, F. Shi, A.L. Rakhmilevich, P.M. Sondel, D.M. Mahvi, N.S. Yang Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNA Proc. Natl. Acad. Sci. USA 96 1999 13351
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13351
-
-
Oshikawa, K.1
Shi, F.2
Rakhmilevich, A.L.3
Sondel, P.M.4
Mahvi, D.M.5
Yang, N.S.6
-
11
-
-
0035915810
-
Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer
-
K. Oshikawa, A.L. Rakhmilevich, F. Shi, P.M. Sondel, N. Yang, D.M. Mahvi Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer Hum. Gene Ther. 12 2001 149
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 149
-
-
Oshikawa, K.1
Rakhmilevich, A.L.2
Shi, F.3
Sondel, P.M.4
Yang, N.5
Mahvi, D.M.6
-
12
-
-
0033104852
-
Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12
-
L. Yao, C. Sgadari, K. Furuke, E.T. Bloom, J. Teruya-Feldstein, G. Tosato Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12 Blood 93 1999 1612
-
(1999)
Blood
, vol.93
, pp. 1612
-
-
Yao, L.1
Sgadari, C.2
Furuke, K.3
Bloom, E.T.4
Teruya-Feldstein, J.5
Tosato, G.6
-
13
-
-
0029922177
-
Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
-
C. Sgadari, A.L. Angiolillo, G. Tosato Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10 Blood 87 1996 3877
-
(1996)
Blood
, vol.87
, pp. 3877
-
-
Sgadari, C.1
Angiolillo, A.L.2
Tosato, G.3
-
14
-
-
0030475607
-
A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12
-
A.L. Angiolillo, C. Sgadari, G. Tosato A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12 Ann. NY Acad. Sci. 795 1996 158
-
(1996)
Ann. NY Acad. Sci.
, vol.795
, pp. 158
-
-
Angiolillo, A.L.1
Sgadari, C.2
Tosato, G.3
-
15
-
-
0027155874
-
In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment
-
L. Cheng, P.R. Ziegelhoffer, N.S. Yang In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment Proc. Natl. Acad. Sci. USA 90 1993 4455
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4455
-
-
Cheng, L.1
Ziegelhoffer, P.R.2
Yang, N.S.3
-
16
-
-
0030879639
-
Cytokine gene therapy of cancer using gene gun technology: Superior antitumor activity of interleukin-12
-
A.L. Rakhmilevich, K. Janssen, J. Turner, J. Culp, N.S. Yang Cytokine gene therapy of cancer using gene gun technology superior antitumor activity of interleukin-12 Hum. Gene Ther. 8 1997 1303
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1303
-
-
Rakhmilevich, A.L.1
Janssen, K.2
Turner, J.3
Culp, J.4
Yang, N.S.5
-
17
-
-
0028987902
-
Role of interferon-gamma in mediating the antitumor efficacy of interleukin-12
-
M.J. Brunda, L. Luistro, J.A. Hendrzak, M. Fountoulakis, G. Garotta, M.K. Gately Role of interferon-gamma in mediating the antitumor efficacy of interleukin-12 J. Immunother. Emphasis Tumor Immunol. 17 1995 71
-
(1995)
J. Immunother. Emphasis Tumor Immunol.
, vol.17
, pp. 71
-
-
Brunda, M.J.1
Luistro, L.2
Hendrzak, J.A.3
Fountoulakis, M.4
Garotta, G.5
Gately, M.K.6
-
18
-
-
0029090220
-
Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes
-
J. Mu, J.P. Zou, N. Yamamoto, T. Tsutsui, X.G. Tai, M. Kobayashi, S. Herrmann, H. Fujiwara, T. Hamaoka Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes Cancer Res. 55 1995 4404
-
(1995)
Cancer Res.
, vol.55
, pp. 4404
-
-
Mu, J.1
Zou, J.P.2
Yamamoto, N.3
Tsutsui, T.4
Tai, X.G.5
Kobayashi, M.6
Herrmann, S.7
Fujiwara, H.8
Hamaoka, T.9
-
19
-
-
0029898839
-
Amount of interleukin 12 available at the tumor site is critical for tumor regression
-
M.P. Colombo, M. Vagliani, F. Spreafico, M. Parenza, C. Chiodoni, C. Melani, A. Stoppacciaro Amount of interleukin 12 available at the tumor site is critical for tumor regression Cancer Res. 56 1996 2531
-
(1996)
Cancer Res.
, vol.56
, pp. 2531
-
-
Colombo, M.P.1
Vagliani, M.2
Spreafico, F.3
Parenza, M.4
Chiodoni, C.5
Melani, C.6
Stoppacciaro, A.7
-
20
-
-
0029947820
-
Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
-
A.L. Rakhmilevich, J. Turner, M.J. Ford, D. McCabe, W.H. Sun, P.M. Sondel, K. Grota, N.S. Yang Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors Proc. Natl. Acad. Sci. USA 93 1996 6291
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6291
-
-
Rakhmilevich, A.L.1
Turner, J.2
Ford, M.J.3
McCabe, D.4
Sun, W.H.5
Sondel, P.M.6
Grota, K.7
Yang, N.S.8
-
21
-
-
0036932417
-
Antitumor effect to IL-12 administration into the portal vein on murine liver metastasis
-
W. Su, T. Kitagawa, T. Ito, T. Oyama, C.M. Lee, Y.K. Kim, H. Matsuda Antitumor effect to IL-12 administration into the portal vein on murine liver metastasis J. Hepatobiliary Pancreat. Surg. 9 2002 503
-
(2002)
J. Hepatobiliary Pancreat. Surg.
, vol.9
, pp. 503
-
-
Su, W.1
Kitagawa, T.2
Ito, T.3
Oyama, T.4
Lee, C.M.5
Kim, Y.K.6
Matsuda, H.7
-
22
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
F. Liu, Y. Song, D. Liu Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA Gene Ther. 6 1999 1258
-
(1999)
Gene Ther.
, vol.6
, pp. 1258
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
23
-
-
0035080761
-
Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth
-
J. Yang, S. Chen, L. Huang, G.K. Michalopoulos, Y. Liu Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth Hepatology 33 2001 848
-
(2001)
Hepatology
, vol.33
, pp. 848
-
-
Yang, J.1
Chen, S.2
Huang, L.3
Michalopoulos, G.K.4
Liu, Y.5
-
24
-
-
0033166561
-
High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
-
G. Zhang, V. Budker, J.A. Wolff High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA Hum. Gene Ther. 10 1999 1735
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1735
-
-
Zhang, G.1
Budker, V.2
Wolff, J.A.3
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