Apparent absence of BRCA2 protein in a proportion of acute myeloid leukemia cell lines [7]

Leukemia

Volumn 18, Issue 11, 2004, Pages 1918-1920

  Chen, F ^a,b   Medhurst, A L ^a   de Winter, J P ^a   Waisfisz, Q ^a   Rooimans, M A ^a   Oostra, A B ^a   Meyer, S ^c   Zhang, K J ^b   Xia, B ^b   Pals, G ^a   Arwert, F ^a   Zwann, C M ^a   Joenje, H ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b WUHAN UNIVERSITY   (China)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; CANCER CELL CULTURE; CANCER RISK; CELL TYPE; FANCONI ANEMIA; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; HUMAN; IMMUNOBLOTTING; LETTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 8844281534     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403473     Document Type: Letter

References (10)

1. Joenje H, Patel KJ. The emerging genetic and molecular basis of Fanconi anaemia. Nat Rev Genet 2001; 2: 446-457.
2. Levitus M, Rooimans MA, Steltenpool J, Cool NF, Oostra AB, Mathew CG et al. Heterogeneity in Fanconi anemia: evidence for two new genetic subtypes. Blood 2003; 103: 2498-2503.
3. Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 2003; 35: 165-170.
4. Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C et al. Biallelic inactivation of BRCA2 in Fanconi anemia. Science 2002; 297: 606-609.
5. Xie Y, de Winter JP, Waisfisz Q, Nieuwint AW, Scheper RJ, Arwert F et al. Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells. Br J Haematol 2000; 111: 1057-1064.
6. Tischkowitz M, Ameziane N, Waisfisz Q, De Winter JP, Harris R, Taniguchi T et al. Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia. Br J Haematol 2003; 123 469-471.
7. Ikeda H, Matsushita M, Waisfisz Q, Kinoshita A, Oostra AB, Nieuwint AW et al. Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2. Cancer Res 2003; 63: 2688-2694.
8. Aunoble B, Bernard-Gallon D, Bignon YJ. Regulation of BRCA1 and BRCA2 transcript in response to cisplatin, adriamycin, taxol and ionising radiation is correlated to p53 functional status in ovarian cancer cell lines. Oncol Rep 2001; 8: 663-668.
9. Su LK, Wang SC, Qi Y, Luo W, Hung MC, Lin SH. Characterization of BRCA2: temperature sensitivity of detection and cell-cycle regulated expression. Oncogene 1998; 17: 2377-2381.
10. Alter BP. Cancer in Fanconi anemia, 1927-2001. Cancer 2003; 97: 425-440.